|
|---|
| CSGID ID |
Priority |
stage |
Screening |
Locus Tag |
NCBI GI |
Gene
Name |
Common Name |
Sequence
Length |
Selection
Phase |
Homolog
PDB ID |
Homolog
Sequence
Identity |
Target Organism |
TIGR Main Role |
TIGR Subrole |
Request Person |
IDP02329
(show subtarget assignments)
|
1 |
in_pdb
3KQF |
Yes |
GBAA2551 |
47527840 |
|
enoyl-CoA hydratase [Bacillus anthracis ... |
262 |
Phase 3: June 2008 |
3KQF
|
100% |
Bacillus anthracis |
Fatty acid and phospholipid metabolism |
Degradation |
|
|
|
IDP02330
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA1419 |
47526691 |
ilvC-1 |
ketol-acid reductoisomerase [Bacillus an... |
336 |
Phase 3: June 2008 |
1NP3
|
55.7% |
Bacillus anthracis |
Amino acid biosynthesis |
Pyruvate family |
|
|
|
IDP02331
(show subtarget assignments)
|
1 |
selected |
No |
GBAA2661 |
47527952 |
adP-1 |
alkaline d-peptidase [Bacillus anthracis... |
388 |
Phase 3: June 2008 |
1CEF
|
30.7% |
Bacillus anthracis |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP02332
(show subtarget assignments)
|
1 |
purified |
No |
GBAA1462 |
47526735 |
|
UbiE/COQ5 family methlytransferase [Baci... |
258 |
Phase 3: June 2008 |
3UJD
|
22.5% |
Bacillus anthracis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Menaquinone and ubiquinone |
|
|
|
IDP02333
(show subtarget assignments)
|
1 |
soluble |
No |
FTT0625 |
56707750 |
clpX |
ATP-dependent protease ATP-binding subun... |
417 |
Phase 3: June 2008 |
3HWS
|
54.7% |
Francisella tularensis |
Protein fate |
Protein folding and stabilizationDegradation of proteins, peptides, and glycopeptides |
|
|
|
IDP02334
(show subtarget assignments)
|
1 |
soluble |
No |
FTT0391c |
56707540 |
cspC |
cold shock protein [Francisella tularens... |
67 |
Phase 3: June 2008 |
3I2Z
|
61.8% |
Francisella tularensis |
Cellular processes |
Adaptations to atypical conditions |
|
|
|
IDP02335
(show subtarget assignments)
|
1 |
expressed |
No |
GBAA2583 |
47527873 |
|
hypothetical protein GBAA2583 [Bacillus ... |
563 |
Phase 3: June 2008 |
3SKS
|
26.3% |
Bacillus anthracis |
Hypothetical proteins |
Conserved |
|
|
|
IDP02336
(show subtarget assignments)
|
1 |
expressed |
No |
YPO2533 |
16122751 |
edd |
phosphogluconate dehydratase [Yersinia p... |
625 |
Phase 3: June 2008 |
2GP4
|
63.8% |
Yersinia pestis |
Energy metabolism |
Entner-Doudoroff |
|
|
|
IDP02337
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
GBAA1511 |
47526786 |
gdhA |
glutamate dehydrogenase [Bacillus anthra... |
428 |
Phase 3: June 2008 |
3K8Z
|
84.1% |
Bacillus anthracis |
Amino acid biosynthesis |
Glutamate family |
|
|
|
IDP02338
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA1456 |
47526731 |
|
sensor histidine kinase [Bacillus anthra... |
351 |
Phase 3: June 2008 |
3EHH
|
14.2% |
Bacillus anthracis |
Regulatory functions |
Protein interactions |
|
|
|
IDP02339
(show subtarget assignments)
|
1 |
expressed |
No |
YPO2647 |
16122856 |
proV |
glycine betaine/L-proline transport ATP-... |
399 |
Phase 3: June 2008 |
3FVQ
|
25.1% |
Yersinia pestis |
Transport and binding proteins |
Amino acids, peptides and amines |
|
|
|
IDP02340
(show subtarget assignments)
|
1 |
soluble |
No |
GBAA2884 |
47528179 |
|
hypothetical protein GBAA2884 [Bacillus ... |
281 |
Phase 3: June 2008 |
|
|
Bacillus anthracis |
Hypothetical proteins |
Conserved |
|
|
|
IDP02341
(show subtarget assignments)
|
1 |
cloned |
No |
FTT1313c |
56708370 |
greA |
transcriptional elongation factor [Franc... |
160 |
Phase 3: June 2008 |
1GRJ
|
63.1% |
Francisella tularensis |
Regulatory functions |
Other |
|
|
|
IDP02342
(show subtarget assignments)
|
1 |
expressed |
No |
Cj0737 |
15792086 |
|
putative periplasmic protein [Campylobac... |
358 |
Phase 3: June 2008 |
2ODL
|
28.8% |
Campylobacter jejuni |
Transport and binding proteins |
Other |
|
|
|
IDP02343
(show subtarget assignments)
|
1 |
expressed |
No |
STM0345 |
16763725 |
|
putative inner membrane protein [Salmone... |
162 |
Phase 3: June 2008 |
|
|
Salmonella enterica |
Hypothetical proteins |
Conserved |
|
|
|
IDP02344
(show subtarget assignments)
|
1 |
cloned |
No |
FTT0356 |
56707508 |
htpG |
heat shock protein 90 [Francisella tular... |
628 |
Phase 3: June 2008 |
2IOP
|
52.4% |
Francisella tularensis |
Cell envelopeProtein fate |
Surface structuresProtein folding and stabilization |
|
|
|
IDP02345
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
FTT1220 |
56708282 |
|
5-formyltetrahydroformate cycloligase fa... |
182 |
Phase 3: June 2008 |
2JCB
|
28.6% |
Francisella tularensis |
Unclassified |
Role category not yet assigned |
|
|
|
IDP02346
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA2832 |
47528125 |
dapA-1 |
dihydrodipicolinate synthase [Bacillus a... |
298 |
Phase 3: June 2008 |
3NA8
|
34.2% |
Bacillus anthracis |
Amino acid biosynthesis |
Aspartate family |
|
|
|
IDP02347
(show subtarget assignments)
|
1 |
soluble |
No |
YPO1783 |
16122037 |
ftnA |
ferritin [Yersinia pestis CO92] |
169 |
Phase 3: June 2008 |
3QZ3
|
68.6% |
Yersinia pestis |
Transport and binding proteins |
Cations and iron carrying compounds |
|
|
|
IDP02348
(show subtarget assignments)
|
1 |
soluble |
No |
GBAA2803 |
47528096 |
|
S-layer protein, putative [Bacillus anth... |
461 |
Phase 3: June 2008 |
3PYW
|
12.4% |
Bacillus anthracis |
Cell envelope |
Surface structures |
|
|
|
IDP02349
(show subtarget assignments)
|
1 |
purified |
No |
GBAA5069 |
47778360 |
|
LPXTG-site transpeptidase family protein... |
198 |
Phase 3: June 2008 |
2XWG
|
24.7% |
Bacillus anthracis |
Cell envelope |
Other |
|
|
|
IDP02350
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
YPO2977 |
16123158 |
glk |
glucokinase [Yersinia pestis CO92] |
323 |
Phase 3: June 2008 |
1Q18
|
78.6% |
Yersinia pestis |
Energy metabolism |
Glycolysis/gluconeogenesis |
|
|
|
IDP02351
(show subtarget assignments)
|
1 |
cloned |
No |
FTT1112c |
56708190 |
rpoH |
RNA polymerase factor sigma-32 [Francise... |
292 |
Phase 3: June 2008 |
1IW7
|
25% |
Francisella tularensis |
Cellular processesTranscription |
Adaptations to atypical conditionsTranscription factors |
|
|
|
IDP02352
(show subtarget assignments)
|
1 |
cloned |
No |
FTT1334c |
56708390 |
|
hypothetical protein FTT1334c [Francisel... |
169 |
Phase 3: June 2008 |
|
|
Francisella tularensis |
Unclassified |
Role category not yet assigned |
|
|
|
IDP02353
(show subtarget assignments)
|
1 |
soluble |
No |
YPO1374 |
16121654 |
trxB |
thioredoxin reductase [Yersinia pestis C... |
320 |
Phase 3: June 2008 |
1CL0
|
85% |
Yersinia pestis |
Energy metabolism |
Electron transport |
|
|
|
IDP02354
(show subtarget assignments)
|
1 |
cloned |
No |
Cj0887c |
15792217 |
flaD |
flagellar hook-associated protein [Campy... |
750 |
Phase 3: June 2008 |
1UCU
|
13.9% |
Campylobacter jejuni |
Cell envelope |
Other |
|
|
|
IDP02355
(show subtarget assignments)
|
1 |
in_pdb
3JTJ |
Yes |
YPO1400 |
16121680 |
kdsB |
3-deoxy-manno-octulosonate cytidylyltran... |
250 |
Phase 3: June 2008 |
3JTJ
|
100% |
Yersinia pestis |
Cell envelope |
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
|
|
|
IDP02356
(show subtarget assignments)
|
1 |
cloned |
No |
FTT1296 |
56708355 |
ubiE |
menaquinone biosynthesis methyltransfera... |
250 |
Phase 3: June 2008 |
2AVN
|
20% |
Francisella tularensis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Menaquinone and ubiquinone |
|
|
|
IDP02357
(show subtarget assignments)
|
1 |
selected |
No |
GBAA1817 |
47527105 |
|
N-acetylmuramoyl-L-alanine amidase [Baci... |
414 |
Phase 3: June 2008 |
3PYW
|
36.2% |
Bacillus anthracis |
Cell envelope |
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
|
|
|
IDP02358
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
YPO1667 |
16121931 |
cheW |
purine-binding chemotaxis protein [Yersi... |
165 |
Phase 3: June 2008 |
2HO9
|
83% |
Yersinia pestis |
Cellular processes |
Chemotaxis and motility |
|
|
|
IDP02359
(show subtarget assignments)
|
1 |
purified |
No |
Cj0319 |
15791687 |
fliG |
flagellar motor switch protein G [Campyl... |
342 |
Phase 3: June 2008 |
3PKR
|
49.1% |
Campylobacter jejuni |
Cell envelope |
Surface structures |
|
|
|
IDP02360
(show subtarget assignments)
|
1 |
soluble |
No |
FTT1270c |
56708330 |
grpE |
heat shock protein GrpE [Francisella tul... |
195 |
Phase 3: June 2008 |
1DKG
|
36.9% |
Francisella tularensis |
Protein fate |
Protein folding and stabilization |
|
|
|
IDP02361
(show subtarget assignments)
|
1 |
expressed |
No |
CBU_1550 |
29542109 |
ptsP |
phosphoenolpyruvate-protein phosphotrans... |
759 |
Phase 3: June 2008 |
2HRO
|
28.3% |
Coxiella burnetii |
Signal transduction |
PTS |
|
|
|
IDP02362
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA1923 |
47777980 |
ldh |
L-lactate dehydrogenase [Bacillus anthra... |
314 |
Phase 3: June 2008 |
3PQD
|
64.6% |
Bacillus anthracis |
Energy metabolism |
Anaerobic |
|
|
|
IDP02363
(show subtarget assignments)
|
1 |
purified |
No |
FTT1366c |
56708419 |
pyk |
pyruvate kinase [Francisella tularensis ... |
478 |
Phase 3: June 2008 |
1E0U
|
39.5% |
Francisella tularensis |
Energy metabolism |
Glycolysis/gluconeogenesis |
|
|
|
IDP02364
(show subtarget assignments)
|
1 |
cloned |
No |
Cj0365c |
15791732 |
|
putative outer membrane channel protein ... |
492 |
Phase 3: June 2008 |
3PIK
|
24.8% |
Campylobacter jejuni |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP02365
(show subtarget assignments)
|
1 |
purified |
No |
FTT0403 |
56707552 |
def1 |
peptide deformylase [Francisella tularen... |
211 |
Phase 3: June 2008 |
3M6O
|
28.4% |
Francisella tularensis |
Protein fate |
Protein modification and repair |
|
|
|
IDP02366
(show subtarget assignments)
|
1 |
expressed |
No |
YPO2061 |
16122300 |
znuA |
high-affinity zinc transporter periplasm... |
318 |
Phase 3: June 2008 |
2OGW
|
63.5% |
Yersinia pestis |
Transport and binding proteins |
Cations and iron carrying compounds |
|
|
|
IDP02367
(show subtarget assignments)
|
1 |
soluble |
No |
GBAA0213 |
47525471 |
|
1-acyl-sn-glycerol-3-phosphate acyltrans... |
201 |
Phase 3: June 2008 |
|
|
Bacillus anthracis |
Fatty acid and phospholipid metabolism |
Biosynthesis |
|
|
|
IDP02368
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
FTT0422 |
56707569 |
murF |
UDP-N--acetylmuramoylalanyl-D-glutamyl-2... |
452 |
Phase 3: June 2008 |
1GG4
|
33.6% |
Francisella tularensis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP02369
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
GBAA3204 |
47778134 |
|
short chain dehydrogenase [Bacillus anth... |
257 |
Phase 3: June 2008 |
3ICC
|
61.9% |
Bacillus anthracis |
Unknown function |
Enzymes of unknown specificity |
|
|
|
IDP02370
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
GBAA1958 |
47527254 |
fabG |
3-ketoacyl-(acyl-carrier-protein) reduct... |
242 |
Phase 3: June 2008 |
3OEC
|
40.9% |
Bacillus anthracis |
Unknown function |
Enzymes of unknown specificity |
|
|
|
IDP02371
(show subtarget assignments)
|
1 |
expressed |
No |
CBU_1904 |
29542461 |
ftsE |
cell division ABC transporter, ATP-bindi... |
217 |
Phase 3: June 2008 |
1F3O
|
38.1% |
Coxiella burnetii |
Transport and binding proteins |
Unknown substrate |
|
|
|
IDP02372
(show subtarget assignments)
|
1 |
in_pdb
3P7M |
No |
FTT0535c |
56707668 |
mdh |
lactate dehydrogenase [Francisella tular... |
319 |
Phase 3: June 2008 |
3P7M
|
100% |
Francisella tularensis |
Energy metabolism |
TCA cycle |
|
|
|
IDP02373
(show subtarget assignments)
|
1 |
expressed |
No |
FTT0438 |
56707582 |
mpl |
UDP-N-acetylmuramate:L-alanyl-gamma-D-gl... |
456 |
Phase 3: June 2008 |
3HN7
|
41.6% |
Francisella tularensis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP02374
(show subtarget assignments)
|
1 |
purified |
No |
GBAA3116 |
47528407 |
ppsA |
phosphoenolpyruvate synthase [Bacillus a... |
868 |
Phase 3: June 2008 |
2OLS
|
15.7% |
Bacillus anthracis |
Energy metabolism |
Glycolysis/gluconeogenesis |
|
|
|
IDP02375
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
GBAA4701 |
47530000 |
engB |
GTPase EngB [Bacillus anthracis str. 'Am... |
198 |
Phase 3: June 2008 |
1SUL
|
72.2% |
Bacillus anthracis |
Unknown function |
General |
|
|
|
IDP02376
(show subtarget assignments)
|
1 |
cloned |
No |
FTT0451 |
56707593 |
murD |
UDP-N-acetylmuramoylalanine--D-glutamate... |
416 |
Phase 3: June 2008 |
1E0D
|
31.8% |
Francisella tularensis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP02377
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
GBAA1442 |
47526717 |
cysC |
adenylylsulfate kinase [Bacillus anthrac... |
197 |
Phase 3: June 2008 |
3UIE
|
51.3% |
Bacillus anthracis |
Central intermediary metabolism |
Sulfur metabolism |
|
|
|
IDP02378
(show subtarget assignments)
|
1 |
cloned |
No |
CBU_1675 |
29542234 |
kdsA |
2-dehydro-3-deoxyphosphooctonate aldolas... |
280 |
Phase 3: June 2008 |
3T4C
|
62.5% |
Coxiella burnetii |
Cell envelope |
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
|
|
|
IDP02379
(show subtarget assignments)
|
1 |
expressed |
No |
FTT1257 |
56708319 |
emrA1 |
HlyD family secretion protein [Francisel... |
340 |
Phase 3: June 2008 |
4DK0
|
22.1% |
Francisella tularensis |
Cellular processesTransport and binding proteins |
Toxin production and resistanceOther |
|
|
|
IDP02380
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
GBAA1969 |
47527264 |
thrC |
threonine synthase [Bacillus anthracis s... |
352 |
Phase 3: June 2008 |
2ZSJ
|
58% |
Bacillus anthracis |
Amino acid biosynthesis |
Aspartate family |
|
|
|
IDP02381
(show subtarget assignments)
|
1 |
expressed |
No |
GBAA2279 |
47527580 |
proV-1 |
glycine betaine/L-proline ABC transporte... |
315 |
Phase 3: June 2008 |
1Z47
|
36.2% |
Bacillus anthracis |
Transport and binding proteins |
Amino acids, peptides and amines |
|
|
|
IDP02382
(show subtarget assignments)
|
1 |
cloned |
No |
lmo0320 |
16802365 |
|
hypothetical protein lmo0320 [Listeria m... |
399 |
Phase 3: June 2008 |
|
|
Listeria monocytogenes |
Cell envelope |
Other |
|
|
|
IDP02383
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
FTT0489c |
56707631 |
trxB |
thioredoxin reductase [Francisella tular... |
316 |
Phase 3: June 2008 |
1CL0
|
66.8% |
Francisella tularensis |
Energy metabolism |
Electron transport |
|
|
|
IDP02384
(show subtarget assignments)
|
1 |
expressed |
No |
GBAA3202 |
47528494 |
hscC |
chaperone protein hscC [Bacillus anthrac... |
566 |
Phase 3: June 2008 |
2V7Y
|
38% |
Bacillus anthracis |
Protein fate |
Protein folding and stabilization |
|
|
|
IDP02385
(show subtarget assignments)
|
1 |
cloned |
No |
Cj0755 |
15792094 |
cfrA |
putative iron uptake protein [Campylobac... |
696 |
Phase 3: June 2008 |
2HDF
|
29.8% |
Campylobacter jejuni |
Hypothetical proteins |
Conserved |
|
|
|
IDP02386
(show subtarget assignments)
|
1 |
selected |
No |
GBAA3086 |
47528378 |
|
Signal peptidase I [Bacillus anthracis s... |
173 |
Phase 3: June 2008 |
1B12
|
10.4% |
Bacillus anthracis |
Protein fate |
Protein and peptide secretion and trafficking |
|
|
|
IDP02387
(show subtarget assignments)
|
1 |
expressed |
No |
FTT1304c |
56708362 |
murB |
UDP-N-acetylenolpyruvoylglucosamine redu... |
282 |
Phase 3: June 2008 |
3TX1
|
33.7% |
Francisella tularensis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP02388
(show subtarget assignments)
|
1 |
soluble |
No |
YPO1407 |
16121687 |
|
hypothetical protein YPO1407 [Yersinia p... |
618 |
Phase 3: June 2008 |
1A9U
|
25.6% |
Yersinia pestis |
Cell envelope |
Other |
|
|
|
IDP02389
(show subtarget assignments)
|
1 |
cloned |
No |
lmo0232 |
16802278 |
clpC |
endopeptidase Clp ATP-binding chain C [L... |
820 |
Phase 3: June 2008 |
3PXI
|
72.8% |
Listeria monocytogenes |
Energy metabolism |
ATP-proton motive force interconversion |
|
|
|
IDP02390
(show subtarget assignments)
|
1 |
cloned |
No |
CBU_1718 |
29542276 |
groEL |
chaperonin, 60 kDa [Coxiella burnetii RS... |
552 |
Phase 3: June 2008 |
2EU1
|
75.5% |
Coxiella burnetii |
Protein fate |
Protein folding and stabilization |
|
|
|
IDP02391
(show subtarget assignments)
|
1 |
cloned |
No |
FTT0534c |
56707667 |
nrdA |
ribonucleotide-diphosphate reductase sub... |
590 |
Phase 3: June 2008 |
2WGH
|
31.2% |
Francisella tularensis |
Purines, pyrimidines, nucleosides, and nucleotides |
2'-Deoxyribonucleotide metabolism |
|
|
|
IDP02392
(show subtarget assignments)
|
1 |
soluble |
No |
GBAA2294 |
47527593 |
|
hypothetical protein GBAA2294 [Bacillus ... |
436 |
Phase 3: June 2008 |
3I4J
|
38.3% |
Bacillus anthracis |
Unknown function |
Enzymes of unknown specificity |
|
|
|
IDP02393
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
FTT1269c |
56708329 |
dnaK |
heat shock protein DnaK [Francisella tul... |
642 |
Phase 3: June 2008 |
2KHO
|
71.3% |
Francisella tularensis |
Protein fate |
Protein folding and stabilization |
|
|
|
IDP02394
(show subtarget assignments)
|
1 |
cloned |
No |
YPO1633 |
16121901 |
phoQ |
sensor protein PhoQ [Yersinia pestis CO9... |
484 |
Phase 3: June 2008 |
1ID0
|
20.9% |
Yersinia pestis |
Regulatory functions |
Other |
|
|
|
IDP02395
(show subtarget assignments)
|
1 |
expressed |
No |
GBAA3321 |
161611191 |
serC |
phosphoserine aminotransferase [Bacillus... |
324 |
Phase 3: June 2008 |
1W23
|
50% |
Bacillus anthracis |
Amino acid biosynthesis |
Serine family |
|
|
|
IDP02396
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
GBAA3604 |
47528890 |
argH-1 |
argininosuccinate lyase [Bacillus anthra... |
502 |
Phase 3: June 2008 |
2E9F
|
27.5% |
Bacillus anthracis |
Amino acid biosynthesis |
Glutamate family |
|
|
|
IDP02397
(show subtarget assignments)
|
1 |
purified |
No |
FTT1326 |
56708383 |
udp |
uridine phosphorylase [Francisella tular... |
267 |
Phase 3: June 2008 |
3O6V
|
43.1% |
Francisella tularensis |
Unclassified |
Role category not yet assigned |
|
|
|
IDP02398
(show subtarget assignments)
|
1 |
in_pdb
3PEI |
Yes |
FTT1318c |
56708375 |
pepA |
cytosol aminopeptidase [Francisella tula... |
479 |
Phase 3: June 2008 |
3PEI
|
100% |
Francisella tularensis |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP02399
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA2559 |
47527848 |
|
D-alanyl-D-alanine carboxypeptidase fami... |
338 |
Phase 3: June 2008 |
1XP4
|
26.3% |
Bacillus anthracis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP02400
(show subtarget assignments)
|
1 |
purified |
No |
YPO3454 |
16123600 |
nrdD |
anaerobic ribonucleoside triphosphate re... |
712 |
Phase 3: June 2008 |
1H78
|
48.2% |
Yersinia pestis |
Purines, pyrimidines, nucleosides, and nucleotides |
2'-Deoxyribonucleotide metabolism |
|
|
|
IDP02401
(show subtarget assignments)
|
1 |
cloned |
No |
Cj0574 |
15791934 |
ilvI |
acetolactate synthase 3 catalytic subuni... |
566 |
Phase 3: June 2008 |
1JSC
|
40.7% |
Campylobacter jejuni |
Hypothetical proteins |
Conserved |
|
|
|
IDP02402
(show subtarget assignments)
|
1 |
purified |
No |
FTT1778c |
56708771 |
|
hypothetical protein FTT1778c [Francisel... |
130 |
Phase 3: June 2008 |
|
|
Francisella tularensis |
Cell envelope |
Other |
|
|
|
IDP02403
(show subtarget assignments)
|
1 |
expressed |
No |
Cj1024c |
15792351 |
|
sigma-54 dependent DNA-binding response ... |
433 |
Phase 3: June 2008 |
3DZD
|
36% |
Campylobacter jejuni |
Transport and binding proteins |
Amino acids, peptides and amines |
|
|
|
IDP02404
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA2730 |
47528021 |
|
neutral protease [Bacillus anthracis str... |
567 |
Phase 3: June 2008 |
1FJ3
|
25.6% |
Bacillus anthracis |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP02405
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
FTT1803c |
56708789 |
trpR |
trp operon repressor [Francisella tulare... |
95 |
Phase 3: June 2008 |
1CO0
|
30.5% |
Francisella tularensis |
Amino acid biosynthesisRegulatory functions |
Aromatic amino acid familyDNA interactions |
|
|
|
IDP02406
(show subtarget assignments)
|
1 |
crystallized |
No |
GBAA2768 |
47528059 |
|
thioredoxin reductase, putative [Bacillu... |
301 |
Phase 3: June 2008 |
3FBS
|
32.1% |
Bacillus anthracis |
Energy metabolism |
Electron transport |
|
|
|
IDP02407
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA3988 |
47529279 |
acpP |
acyl carrier protein [Bacillus anthracis... |
77 |
Phase 3: June 2008 |
2X2B
|
81.8% |
Bacillus anthracis |
Fatty acid and phospholipid metabolism |
Biosynthesis |
|
|
|
IDP02408
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
YPO1418 |
16121698 |
|
23S rRNA m(2)G2445 methyltransferase [Ye... |
706 |
Phase 3: June 2008 |
3V8V
|
74.8% |
Yersinia pestis |
Unclassified |
Role category not yet assigned |
|
|
|
IDP02409
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
Cj0883c |
15792214 |
|
hypothetical protein Cj0883c [Campylobac... |
136 |
Phase 3: June 2008 |
2Y75
|
28.7% |
Campylobacter jejuni |
Energy metabolism |
Electron transport |
|
|
|
IDP02410
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
Cj1328 |
15792651 |
neuC2 |
putative N-acetylglucosamine-6-phosphate... |
384 |
Phase 3: June 2008 |
3BEO
|
20.9% |
Campylobacter jejuni |
Cell envelope |
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
|
|
|
IDP02411
(show subtarget assignments)
|
1 |
expressed |
No |
YPO3640 |
16123782 |
|
hypothetical protein YPO3640 [Yersinia p... |
448 |
Phase 3: June 2008 |
|
|
Yersinia pestis |
Cell envelope |
Other |
|
|
|
IDP02412
(show subtarget assignments)
|
1 |
soluble |
No |
GBAA4760 |
47530059 |
etfB |
electron transfer flavoprotein, beta sub... |
257 |
Phase 3: June 2008 |
1EFP
|
38.2% |
Bacillus anthracis |
Energy metabolism |
Electron transport |
|
|
|
IDP02413
(show subtarget assignments)
|
1 |
cloned |
No |
YPO3568 |
16123712 |
degS |
serine endoprotease [Yersinia pestis CO9... |
362 |
Phase 3: June 2008 |
1SOT
|
63% |
Yersinia pestis |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP02414
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
FTT1154c |
56708225 |
aroB |
3-dehydroquinate synthase [Francisella t... |
359 |
Phase 3: June 2008 |
3OKF
|
44.3% |
Francisella tularensis |
Amino acid biosynthesis |
Aromatic amino acid family |
|
|
|
IDP02415
(show subtarget assignments)
|
1 |
soluble |
No |
CBU_1761 |
29542318 |
|
sensory box sensor histidine kinase/resp... |
657 |
Phase 3: June 2008 |
2C2A
|
11.6% |
Coxiella burnetii |
Signal transduction |
Two-component systems |
|
|
|
IDP02416
(show subtarget assignments)
|
1 |
purified |
No |
FTT1259 |
56708321 |
nadE |
NH(3)-dependent NAD(+) synthetase [Franc... |
249 |
Phase 3: June 2008 |
3FIU
|
100% |
Francisella tularensis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Pyridine nucleotides |
|
|
|
IDP02417
(show subtarget assignments)
|
1 |
cloned |
No |
FTT0812 |
56707923 |
gcvH1 |
glycine cleavage system protein H [Franc... |
126 |
Phase 3: June 2008 |
1ZKO
|
40.5% |
Francisella tularensis |
Energy metabolism |
Amino acids and amines |
|
|
|
IDP02418
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
Cj1279c |
15792603 |
|
fibronectin domain-containing lipoprotei... |
411 |
Phase 3: June 2008 |
1QR4
|
10.9% |
Campylobacter jejuni |
Transcription |
DNA-dependent RNA polymerase |
|
|
|
IDP02419
(show subtarget assignments)
|
1 |
purified |
No |
FTT1447c |
56708489 |
manB |
phosphomannomutase [Francisella tularens... |
494 |
Phase 3: June 2008 |
2F7L
|
25.7% |
Francisella tularensis |
Unclassified |
Role category not yet assigned |
|
|
|
IDP02420
(show subtarget assignments)
|
1 |
expressed |
No |
YPO1501 |
16121774 |
|
putative esterase [Yersinia pestis CO92]... |
280 |
Phase 3: June 2008 |
3I6Y
|
58.9% |
Yersinia pestis |
Central intermediary metabolism |
Other |
|
|
|
IDP02421
(show subtarget assignments)
|
1 |
purified |
No |
Cj0606 |
15791966 |
|
macrolide-specific efflux protein macA [... |
390 |
Phase 3: June 2008 |
4DK0
|
39.2% |
Campylobacter jejuni |
Transport and binding proteins |
Other |
|
|
|
IDP02422
(show subtarget assignments)
|
1 |
cloned |
No |
YPO1666 |
16121930 |
cheA |
chemotaxis protein CheA [Yersinia pestis... |
723 |
Phase 3: June 2008 |
1B3Q
|
22.7% |
Yersinia pestis |
Cellular processes |
Chemotaxis and motility |
|
|
|
IDP02423
(show subtarget assignments)
|
1 |
cloned |
No |
FTT1138 |
56708213 |
hemH |
ferrochelatase [Francisella tularensis s... |
333 |
Phase 3: June 2008 |
1HRK
|
27.7% |
Francisella tularensis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Heme, porphyrin, and cobalamin |
|
|
|
IDP02424
(show subtarget assignments)
|
1 |
cloned |
No |
FTT1147c |
56708218 |
dfp |
4'-phosphopantothenoylcysteine decarboxy... |
391 |
Phase 3: June 2008 |
1U7U
|
19.4% |
Francisella tularensis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Pantothenate and coenzyme A |
|
|
|
IDP02425
(show subtarget assignments)
|
1 |
soluble |
No |
GBAA2775 |
47528067 |
acoB |
TPP-dependent acetoin dehydrogenase E1 b... |
344 |
Phase 3: June 2008 |
1W85
|
43.9% |
Bacillus anthracis |
Energy metabolism |
Fermentation |
|
|
|
IDP02426
(show subtarget assignments)
|
1 |
cloned |
No |
CBU_1952 |
29542507 |
|
ABC transporter, ATP-binding protein [Co... |
532 |
Phase 3: June 2008 |
2IW3
|
26.4% |
Coxiella burnetii |
Transport and binding proteins |
Unknown substrate |
|
|
|
IDP02427
(show subtarget assignments)
|
1 |
purified |
No |
GBAA3553 |
47528837 |
pepF-2 |
oligoendopeptidase F [Bacillus anthracis... |
595 |
Phase 3: June 2008 |
2QR4
|
37.6% |
Bacillus anthracis |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP02428
(show subtarget assignments)
|
1 |
expressed |
No |
GBAA3580 |
47528865 |
|
O-acetyltransferase, putative [Bacillus ... |
188 |
Phase 3: June 2008 |
3VBI
|
99.5% |
Bacillus anthracis |
Cell envelope |
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
|
|
|
