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Targets
Filter Targets:
Selection Phase:
No Filter
Community Interest
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM10+
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
[Clostridium] difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
0
1
6
8
Keyword:
Type Keyword
Stage:
No Filter
cloned
crystallized
crystal_structure
diffraction
expressed
in_crystallization_trials
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Screening
No Filter
Yes
No
Remove Filters
Download data as tab-separated value (TSV) file
(which can be used as a input for Microsoft Office Excel and Open Office Calc)
Jump to Target:
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IDP#
NCBI GI
LOCUS TAG
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Page 24 of 60, showing 100 records out of 5973 total, starting on record 2301
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CSGID ID
Priority
stage
Screening
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP05015
(
show subtarget assignments
)
1
cloned
No
CD0247
126697818
fliE
flagellar hook-basal body protein FliE [...
105
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
Clostridium difficile
Cellular processes: Chemotaxis and motility
IDP05498
(
show subtarget assignments
)
1
cloned
No
CD0249
126697820
fliG
flagellar motor switch protein [Clostrid...
356
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
3PKR
28.4%
Clostridium difficile
Cellular processes: Chemotaxis and motility
IDP05161
(
show subtarget assignments
)
1
cloned
No
BA_1671
30255967
putative flagellar hook-associated FliD ...
450
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cellular processes: Chemotaxis and motility
IDP05163
(
show subtarget assignments
)
1
cloned
No
BA_1719
30256005
putative flagellar basal-body rod protei...
257
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cellular processes: Chemotaxis and motility
IDP05500
(
show subtarget assignments
)
1
cloned
No
CD0261
126697833
fliQ
flagellar export protein [Clostridium di...
89
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
Clostridium difficile
Cellular processes: Chemotaxis and motility
IDP05385
(
show subtarget assignments
)
1
in_crystallization_trials
No
BA_1686
30255979
putative flagellar hook protein FlgE [Ba...
437
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3A69
30.9%
Bacillus anthracis
Cellular processes: Chemotaxis and motility
IDP05501
(
show subtarget assignments
)
1
in_crystallization_trials
No
CD0270
126697842
fliM
putative flagellar motor switch protein ...
293
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
2HP7
15.7%
Clostridium difficile
Cellular processes: Chemotaxis and motility
IDP05318
(
show subtarget assignments
)
1
soluble
No
lmo0697
16802739
-
flagellar hook protein FlgE [Listeria mo...
411
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3A69
30.6%
Listeria monocytogenes
Cellular processes: Chemotaxis and motility
IDP05286
(
show subtarget assignments
)
1
cloned
No
CD0232
126697803
flgL
flagellar hook-associated protein [Clost...
310
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
3PWX
17.1%
Clostridium difficile
Cellular processes: Chemotaxis and motility
IDP05287
(
show subtarget assignments
)
1
cloned
No
CD0245
126697816
flgB
flagellar basal-body rod protein [Clostr...
97
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
Clostridium difficile
Cellular processes: Chemotaxis and motility
IDP05288
(
show subtarget assignments
)
1
expressed
No
CD0252
126697823
fliJ
flagellar protein [Clostridium difficile...
148
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
Clostridium difficile
Cellular processes: Chemotaxis and motility
IDP05279
(
show subtarget assignments
)
1
in_crystallization_trials
No
CD0254
126697825
flgD
putative basal-body rod modification pro...
202
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
Clostridium difficile
Cellular processes: Chemotaxis and motility
IDP05282
(
show subtarget assignments
)
1
soluble
No
CD0228
126697799
fliN
flagellar motor switch protein [Clostrid...
104
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
1O6A
23.1%
Clostridium difficile
Cellular processes: Chemotaxis and motility
IDP05262
(
show subtarget assignments
)
1
in_pdb
4EBH
3SRT
No
CD0872
126698449
maa
maltose O-acetyltransferase [Clostridium...
185
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
3SRT
100%
Clostridium difficile
Cellular processes: Detoxification
IDP05198
(
show subtarget assignments
)
1
cloned
No
CD1433
126699037
putative bifunctional protein: peroxired...
709
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
1ITX
17.3%
Clostridium difficile
Cellular processes: Detoxification
IDP05576
(
show subtarget assignments
)
1
cloned
No
BA_0536
30254062
bcP
bacterioferritin comigratory protein [Ba...
151
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3DRN
41.7%
Bacillus anthracis
Cellular processes: Detoxification
IDP05061
(
show subtarget assignments
)
1
cloned
No
CD1631
126699235
sodA
superoxide dismutase (Mn) [Clostridium d...
234
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
2RCV
47%
Clostridium difficile
Cellular processes: Detoxification
IDP05520
(
show subtarget assignments
)
1
soluble
No
CD1822
126699430
bcp
putative thiol peroxidase (bacterioferri...
154
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
3DRN
42.6%
Clostridium difficile
Cellular processes: Detoxification
IDP05490
(
show subtarget assignments
)
1
soluble
No
BA_5139
30259623
sodC
superoxide dismutase, Cu-Zn [Bacillus an...
179
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1XTM
35.2%
Bacillus anthracis
Cellular processes: Detoxification
IDP05464
(
show subtarget assignments
)
1
expressed
No
BA_1489
30255419
superoxide dismutase [Bacillus anthracis...
304
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1P7G
35.5%
Bacillus anthracis
Cellular processes: Detoxification
IDP91254
(
show subtarget assignments
)
8
soluble
No
NT02SA0910
14246689
probable 2-nitropropane dioxygenase [Sta...
355
potential drug target /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3BW2
34.9%
Staphylococcus aureus
Cellular processes: Detoxification
IDP05008
(
show subtarget assignments
)
1
cloned
No
CD1777
126699386
putative arsenate reductase [Clostridium...
120
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
3FZ4
41.7%
Clostridium difficile
Cellular processes: Detoxification
IDP05171
(
show subtarget assignments
)
1
expressed
No
lmo1439
16803479
sod
superoxide dismutase [Listeria monocytog...
202
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2RCV
73.3%
Listeria monocytogenes
Cellular processes: Detoxification
IDP05402
(
show subtarget assignments
)
1
soluble
No
BA_4463
30258957
comGD
comG operon protein 4 [Bacillus anthraci...
151
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cellular processes: DNA transformation
IDP05403
(
show subtarget assignments
)
1
soluble
No
BA_4464
30258958
comGC
comG operon protein 3 [Bacillus anthraci...
99
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cellular processes: DNA transformation
IDP05663
(
show subtarget assignments
)
1
selected
No
lmo0333
16802378
-
hypothetical protein lmo0333 [Listeria m...
1778
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1ZIW
9.1%
Listeria monocytogenes
Cellular processes: Pathogenesis
IDP05666
(
show subtarget assignments
)
1
soluble
No
lmo0433
16802477
inlA
internalin A [Listeria monocytogenes EGD...
800
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1O6S
57.6%
Listeria monocytogenes
Cellular processes: Pathogenesis
IDP05656
(
show subtarget assignments
)
1
cloned
No
lmo0171
16802219
-
hypothetical protein lmo0171 [Listeria m...
832
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2OMX
13.7%
Listeria monocytogenes
Cellular processes: Pathogenesis
IDP05222
(
show subtarget assignments
)
1
soluble
No
lmo0153
16802201
-
hypothetical protein lmo0153 [Listeria m...
313
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2O1E
52.1%
Listeria monocytogenes
Cellular processes: Pathogenesis
IDP05212
(
show subtarget assignments
)
1
cloned
No
CD2696
126700310
putative aminotransferase [Clostridium d...
396
virulence/pathogenesis /
Targets associated with virulence and/or pathogenesis
Phase 5: 2010
4DGT
43.2%
Clostridium difficile
Cellular processes: Pathogenesis
IDP05076
(
show subtarget assignments
)
1
soluble
No
lmo0801
16802843
-
hypothetical protein lmo0801 [Listeria m...
646
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1M9S
22.1%
Listeria monocytogenes
Cellular processes: Pathogenesis
IDP05548
(
show subtarget assignments
)
1
cloned
No
lmo0409
16802454
-
hypothetical protein lmo0409 [Listeria m...
821
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1O6S
23.8%
Listeria monocytogenes
Cellular processes: Pathogenesis
IDP05553
(
show subtarget assignments
)
1
soluble
No
lmo1136
16803176
-
hypothetical protein lmo1136 [Listeria m...
539
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1O6S
23.6%
Listeria monocytogenes
Cellular processes: Pathogenesis
IDP05023
(
show subtarget assignments
)
1
expressed
No
BAS2353
49185362
-
hemolysin II, C-terminal [Bacillus anthr...
240
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3ANZ
27.9%
Bacillus anthracis
Cellular processes: Pathogenesis
IDP05165
(
show subtarget assignments
)
1
soluble
No
BA_1888
30256549
enterotoxin [Bacillus anthracis str. Ame...
402
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
2NRJ
24.6%
Bacillus anthracis
Cellular processes: Pathogenesis
IDP05423
(
show subtarget assignments
)
1
cloned
No
lmo0263
16802309
inlH
internalin H [Listeria monocytogenes EGD...
548
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1H6U
55.7%
Listeria monocytogenes
Cellular processes: Pathogenesis
IDP05340
(
show subtarget assignments
)
1
in_pdb
3UUW
Yes
CD3450
126701073
putative oxidoreductase [Clostridium dif...
305
virulence/pathogenesis /
Targets associated with virulence and/or pathogenesis
Phase 5: 2010
3UUW
100%
Clostridium difficile
Cellular processes: Pathogenesis
IDP05302
(
show subtarget assignments
)
1
in_pdb
4DQ6
4DGT
No
CD2733
126700348
putative aminotransferase [Clostridium d...
388
virulence/pathogenesis /
Targets associated with virulence and/or pathogenesis
Phase 5: 2010
4DGT
100%
Clostridium difficile
Cellular processes: Pathogenesis
IDP05285
(
show subtarget assignments
)
1
selected
No
CD0663
126698240
tcdA
toxin A [Clostridium difficile 630]
2710
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3SRZ
20%
Clostridium difficile
Cellular processes: Pathogenesis
IDP02665
(
show subtarget assignments
)
1
cloned
No
FTT0469
56707611
ksgA
dimethyladenosine transferase [Francisel...
262
Conserved; Drug target functions
Phase 3: June 2008
3TQS
40.8%
Francisella tularensis
Cellular processesProtein synthesis
Toxin production and resistancetRNA and rRNA base modification
IDP02279
(
show subtarget assignments
)
1
crystallized
No
FTT1164c
56708234
era
GTP-binding protein Era [Francisella tul...
297
Drug Target
Phase 3: June 2008
1EGA
48.5%
Francisella tularensis
Cellular processesRegulatory functions
Cell divisionRNA interactions
IDP05626
(
show subtarget assignments
)
1
soluble
No
CD1430
126699034
putative exported polysaccharide deacety...
274
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1NY1
37.2%
Clostridium difficile
Cellular processes: Sporulation and germination
IDP05219
(
show subtarget assignments
)
1
cloned
No
CD3567
126701193
putative cell wall hydrolase [Clostridiu...
516
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
Clostridium difficile
Cellular processes: Sporulation and germination
IDP05616
(
show subtarget assignments
)
1
cloned
No
CD0124
126697696
spoIIC
stage II sporulation protein D [Clostrid...
354
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cellular processes: Sporulation and germination
IDP05604
(
show subtarget assignments
)
1
expressed
No
BA_4769
30259256
putative spore coat protein C [Bacillus ...
110
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cellular processes: Sporulation and germination
IDP05598
(
show subtarget assignments
)
1
cloned
No
BA_3635
30258161
gerSC
spore germination protein [Bacillus anth...
378
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cellular processes: Sporulation and germination
IDP05572
(
show subtarget assignments
)
1
cloned
No
BAS4090
49187088
-
stage III sporulation protein AH [Bacill...
223
essential/virulence/pathogenesis /
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3TUF
32.7%
Bacillus anthracis
Cellular processes: Sporulation and germination
IDP05584
(
show subtarget assignments
)
1
soluble
No
BA_2341
30256978
gerPF2
spore germination protein GerPF [Bacillu...
79
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cellular processes: Sporulation and germination
IDP05185
(
show subtarget assignments
)
1
purified
No
BA_5528
30259987
spoIID
stage II sporulation protein D [Bacillus...
339
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cellular processes: Sporulation and germination
IDP05587
(
show subtarget assignments
)
1
soluble
No
BA_2748
30257353
sleB
spore cortex-lytic enzyme prepeptide [Ba...
253
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3BKH
19.8%
Bacillus anthracis
Cellular processes: Sporulation and germination
IDP05182
(
show subtarget assignments
)
1
soluble
No
BA_4984
30259476
gerHA
spore germination protein GerHA [Bacillu...
747
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3FBY
7.5%
Bacillus anthracis
Cellular processes: Sporulation and germination
IDP05065
(
show subtarget assignments
)
1
soluble
No
CD2469
126700086
spoIIP
putative stage II sporulation protein P ...
339
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cellular processes: Sporulation and germination
IDP05524
(
show subtarget assignments
)
1
cloned
No
CD2402
126700017
putative cell wall hydrolase [Clostridiu...
396
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3H41
20.5%
Clostridium difficile
Cellular processes: Sporulation and germination
IDP05509
(
show subtarget assignments
)
1
expressed
No
BA_5736
30260182
spoIIIJ2
stage III sporulation protein J [Bacillu...
255
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cellular processes: Sporulation and germination
IDP05489
(
show subtarget assignments
)
1
soluble
No
CD0106
126697677
cwlD
germination-specific N-acetylmuramoyl-L-...
250
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
1JWQ
25.6%
Clostridium difficile
Cellular processes: Sporulation and germination
IDP05457
(
show subtarget assignments
)
1
soluble
No
BA_1144
30254865
gerPF1
spore germination protein GerPF [Bacillu...
71
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cellular processes: Sporulation and germination
IDP05463
(
show subtarget assignments
)
1
soluble
No
BA_1288
30255236
spore coat-associated protein [Bacillus ...
195
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cellular processes: Sporulation and germination
IDP05159
(
show subtarget assignments
)
1
cloned
No
BA_1290
30255237
calY
camelysin [Bacillus anthracis str. Ames]...
197
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cellular processes: Sporulation and germination
IDP05380
(
show subtarget assignments
)
1
soluble
No
BA_0633
30254236
gerKC
spore germination protein GerKC [Bacillu...
374
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3N54
22.7%
Bacillus anthracis
Cellular processes: Sporulation and germination
IDP05381
(
show subtarget assignments
)
1
cloned
No
BA_0711
30254309
gerLC
spore germination protein GerLC [Bacillu...
388
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3N54
24.7%
Bacillus anthracis
Cellular processes: Sporulation and germination
IDP05072
(
show subtarget assignments
)
1
cloned
No
CD3564
126701190
spoIIR
stage II sporulation protein [Clostridiu...
198
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cellular processes: Sporulation and germination
IDP05314
(
show subtarget assignments
)
1
soluble
No
BA_4986
30259478
gerHC
spore germination protein GerHC [Bacillu...
359
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3N54
20.1%
Bacillus anthracis
Cellular processes: Sporulation and germination
IDP05257
(
show subtarget assignments
)
1
crystallized
No
CD2748
126700363
putative transferase [Clostridium diffic...
165
virulence/pathogenesis /
Targets associated with virulence and/or pathogenesis
Phase 5: 2010
2EG0
48.2%
Clostridium difficile
Cellular processes: Toxin production and resistance
IDP05733
(
show subtarget assignments
)
1
cloned
No
CD1208
126698804
putative RNA methyltransferase [Clostrid...
270
virulence/pathogenesis /
Targets associated with virulence and/or pathogenesis
Phase 5: 2010
3HP7
50.7%
Clostridium difficile
Cellular processes: Toxin production and resistance
IDP05730
(
show subtarget assignments
)
1
soluble
No
CD0675
126698254
putative acetyltransferase [Clostridium ...
166
virulence/pathogenesis /
Targets associated with virulence and/or pathogenesis
Phase 5: 2010
2GE3
31.3%
Clostridium difficile
Cellular processes: Toxin production and resistance
IDP05108
(
show subtarget assignments
)
1
in_pdb
4DUN
No
CD1761
126699370
hypothetical protein CD1761 [Clostridium...
260
virulence/pathogenesis /
Targets associated with virulence and/or pathogenesis
Phase 5: 2010
4DUN
100%
Clostridium difficile
Cellular processes: Toxin production and resistance
IDP05528
(
show subtarget assignments
)
1
in_pdb
4E1L
No
CD2676
126700290
thlA2
putative acetyl-CoA acetyltransferase [C...
392
virulence/pathogenesis /
Targets associated with virulence and/or pathogenesis
Phase 5: 2010
4E1L
100%
Clostridium difficile
Cellular processes: Toxin production and resistance
IDP05060
(
show subtarget assignments
)
1
in_pdb
4DD5
Yes
CD1059
126698643
thlA1
acetyl-CoA acetyltransferase [Clostridiu...
396
virulence/pathogenesis /
Targets associated with virulence and/or pathogenesis
Phase 5: 2010
4DD5
100%
Clostridium difficile
Cellular processes: Toxin production and resistance
IDP05290
(
show subtarget assignments
)
1
cloned
No
CD0488
126698065
sugE
quaternary ammonium compound-resistance ...
106
virulence/pathogenesis /
Targets associated with virulence and/or pathogenesis
Phase 5: 2010
2I68
30.2%
Clostridium difficile
Cellular processes: Toxin production and resistance
IDP05291
(
show subtarget assignments
)
1
in_crystallization_trials
No
CD1211
126698807
putative acetyltransferase [Clostridium ...
163
virulence/pathogenesis /
Targets associated with virulence and/or pathogenesis
Phase 5: 2010
1YX0
23.9%
Clostridium difficile
Cellular processes: Toxin production and resistance
IDP01879
(
show subtarget assignments
)
1
cloned
No
FTT1804c
56708790
rng
ribonuclease G [Francisella tularensis s...
498
Conserved; Drug target functions
Phase 3: June 2008
2BX2
31.9%
Francisella tularensis
Cellular processesTranscription
Cell divisionRNA processing
IDP02351
(
show subtarget assignments
)
1
cloned
No
FTT1112c
56708190
rpoH
RNA polymerase factor sigma-32 [Francise...
292
Drug Target
Phase 3: June 2008
1IW7
25%
Francisella tularensis
Cellular processesTranscription
Adaptations to atypical conditionsTranscription factors
IDP02379
(
show subtarget assignments
)
1
expressed
No
FTT1257
56708319
emrA1
HlyD family secretion protein [Francisel...
340
Conserved; Drug target functions
Phase 3: June 2008
4DK0
22.1%
Francisella tularensis
Cellular processesTransport and binding proteins
Toxin production and resistanceOther
IDP00125
(
show subtarget assignments
)
0
work_stopped
No
NT01ST1183
16764320
lrp
leucine-responsive transcriptional regul...
164
Phase 1: October 2007
2GQQ
98.8%
Salmonella enterica
Central intermediary metabolism
Other
IDP04004
(
show subtarget assignments
)
1
cloned
No
CPF_1305
110799423
mtnN
5'-methylthioadenosine/S-adenosylhomocys...
266
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
3EEI
34.6%
Clostridium perfringens
Central intermediary metabolism
Other
IDP02765
(
show subtarget assignments
)
1
in_crystallization_trials
No
GBAA2632
47527924
cytochrome P450 family protein [Bacillus...
404
Conserved; Involved in sporulation; Drug target functions
Phase 3: June 2008
2BVJ
34.9%
Bacillus anthracis
Central intermediary metabolism
Other
IDP01086
(
show subtarget assignments
)
1
in_crystallization_trials
No
STM4404
16767650
cysQ
PAPS (adenosine 3'-phosphate 5'-phosphos...
246
Conserved Gene / Pathway
Phase 2: March 2008
3B8B
48.1%
Salmonella enterica
Central intermediary metabolism
Sulfur metabolism
IDP01074
(
show subtarget assignments
)
1
in_pdb
3FPK
Yes
STM4084
16767350
fpr
ferredoxin-NADP reductase
248
Conserved Gene / Pathway
Phase 2: March 2008
3FPK
100%
Salmonella enterica
Central intermediary metabolism
Other
IDP02174
(
show subtarget assignments
)
1
cloned
No
YPO3031
16123208
putative acetyltransferase [Yersinia pes...
141
Conserved; Proteomics evidence (Cytoplasmid or periplasmic); Drug target functio...
Phase 3: June 2008
2PDO
78%
Yersinia pestis
Central intermediary metabolism
Other
IDP02156
(
show subtarget assignments
)
1
soluble
No
YPO0253
16120590
acs
acetyl-CoA synthetase [Yersinia pestis C...
652
Conserved; CD; Proteomics evidence (Cytoplasmid or periplasmic); Involved in vir...
Phase 3: June 2008
2P2F
83.9%
Yersinia pestis
Central intermediary metabolism
Other
IDP01056
(
show subtarget assignments
)
1
in_pdb
3R3R
Yes
STM3399
16766688
yrdA
putative ferripyochelin-binding protein ...
184
Conserved Gene / Pathway
Phase 2: March 2008
3R3R
100%
Salmonella enterica
Central intermediary metabolism
Other
IDP01053
(
show subtarget assignments
)
1
cloned
No
STM3330
16766625
gltB
glutamate synthase subunit alpha
1486
Conserved Gene / Pathway
Phase 2: March 2008
1EA0
45.2%
Salmonella enterica
Central intermediary metabolism
Other
IDP01049
(
show subtarget assignments
)
1
in_crystallization_trials
No
STM3183
16766483
icc
cyclic 3',5'-adenosine monophosphate pho...
275
Conserved Gene / Pathway
Phase 2: March 2008
2HY1
25.1%
Salmonella enterica
Central intermediary metabolism
Other
IDP02750
(
show subtarget assignments
)
1
cloned
No
GBAA5389
47530699
transferase hexapeptide domain-containin...
170
Conserved; Essential; Drug target functions
Phase 3: June 2008
1KHR
28.8%
Bacillus anthracis
Central intermediary metabolism
Other
IDP02121
(
show subtarget assignments
)
1
cloned
No
FTT0360
56707511
Short-chain dehydrogenase/reductase [Fra...
274
Drug Target
Phase 3: June 2008
1FDW
27.7%
Francisella tularensis
Central intermediary metabolism
Other
IDP01045
(
show subtarget assignments
)
1
soluble
No
STM3114
16766415
speC
ornithine decarboxylase isozyme
711
Conserved Gene / Pathway
Phase 2: March 2008
1ORD
53.8%
Salmonella enterica
Central intermediary metabolism
Polyamine biosynthesis
IDP01039
(
show subtarget assignments
)
1
expressed
No
STM2934
16766240
cysN
sulfate adenylyltransferase subunit 1
479
Conserved Gene / Pathway
Phase 2: March 2008
1ZUN
52.4%
Salmonella enterica
Central intermediary metabolism
Sulfur metabolism
IDP01040
(
show subtarget assignments
)
1
expressed
No
STM2935
16766241
cysD
sulfate adenylyltransferase subunit 2
302
Conserved Gene / Pathway
Phase 2: March 2008
1ZUN
75.2%
Salmonella enterica
Central intermediary metabolism
Sulfur metabolism
IDP02080
(
show subtarget assignments
)
1
in_pdb
3KZ2
3IH1
No
GBAA2350
47527645
yqiQ
carboxyvinyl-carboxyphosphonate phosphor...
302
Conserved; Essential; Involved in sporulation; Drug target functions
Phase 3: June 2008
3IH1
100%
Bacillus anthracis
Central intermediary metabolism
Other
IDP01015
(
show subtarget assignments
)
0
work_stopped
No
STM2791
16766102
gabD
succinate-semialdehyde dehydrogenase I
482
Conserved Gene / Pathway
Phase 2: March 2008
3JZ4
90%
Salmonella enterica
Central intermediary metabolism
Other
IDP02062
(
show subtarget assignments
)
1
soluble
No
CBU_1357
29541922
csdB
selenocysteine lyase [Coxiella burnetii ...
405
Conserved; Drug target functions
Phase 3: June 2008
1I29
50.9%
Coxiella burnetii
Central intermediary metabolism
Other
IDP01016
(
show subtarget assignments
)
1
cloned
No
STM2792
16766103
gabT
4-aminobutyrate aminotransferase
427
Conserved Gene / Pathway
Phase 2: March 2008
1SF2
88.3%
Salmonella enterica
Central intermediary metabolism
Other
IDP02049
(
show subtarget assignments
)
1
expressed
No
STM3122
16766422
putative arylsulfatase [Salmonella typhi...
579
Drug target motif; Conserved; Drug target functions
Phase 3: June 2008
1HDH
36.1%
Salmonella enterica
Central intermediary metabolism
Sulfur metabolism
IDP02045
(
show subtarget assignments
)
1
cloned
No
FTT0749c
56707864
hypothetical protein FTT0749c [Francisel...
328
Conserved; Drug target functions; Drug target motif
Phase 3: June 2008
3AIM
25.6%
Francisella tularensis
Central intermediary metabolism
Other
IDP01003
(
show subtarget assignments
)
1
cloned
No
STM2479
16765799
aegA
putative oxidoreductase Fe-S binding sub...
653
Conserved Gene / Pathway
Phase 2: March 2008
2VDC
29.2%
Salmonella enterica
Central intermediary metabolism
Other
IDP02027
(
show subtarget assignments
)
1
soluble
No
CBU_0599
29541200
cysQ-1
3'(2'),5'-bisphosphate nucleotidase [Cox...
271
Conserved; Drug target functions
Phase 3: June 2008
3B8B
39.5%
Coxiella burnetii
Central intermediary metabolism
Sulfur metabolism
IDP02008
(
show subtarget assignments
)
1
in_crystallization_trials
No
STM3595
16766881
putative phosphatase [Salmonella typhimu...
423
Conserved; Drug target functions
Phase 3: June 2008
2A96
12.8%
Salmonella enterica
Central intermediary metabolism
Other
IDP01975
(
show subtarget assignments
)
1
cloned
No
Cj1442c
15792760
hypothetical protein Cj1442c [Campylobac...
544
Known Predicted virulence-capsule biosynthesis anmd transport; PMID:15808749
Phase 3: June 2008
2FFU
10.5%
Campylobacter jejuni
Central intermediary metabolism
Other
IDP00971
(
show subtarget assignments
)
1
in_pdb
3IAH
Yes
STM1717
16765061
yciK
short chain dehydrogenase
253
Conserved Gene / Pathway
Phase 2: March 2008
3IAH
100%
Salmonella enterica
Central intermediary metabolism
Other
IDP00108
(
show subtarget assignments
)
1
purified
No
NT01SF4751
30043076
fdhE
FdhE protein
309
These targets are similar to actual drug targets and will be used mostly for coc...
Phase 1: October 2007
2FIY
39.5%
Shigella flexneri
Central intermediary metabolism
Other
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