(skip to main content)
Home
Target List
Selection
Community Requests
Clones
Screenings
XML files
Diffraction Images
Progress
Homolog Search
Clustering
Statistics
News
Help
Log In
Consortium
Overview
Investigators
Experiments
X-ray Structures
NMR Structures
Electronic Structure Description
Publications
Resources
Clustering
Related Sites
Progress
Collaborators
Basecamp
Contact Us
Log In
Targets
Filter Targets:
Selection Phase:
No Filter
Community Interest
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM10+
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
[Clostridium] difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
0
1
6
8
Keyword:
Type Keyword
Stage:
No Filter
cloned
crystallized
crystal_structure
diffraction
expressed
in_crystallization_trials
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Screening
No Filter
Yes
No
Remove Filters
Download data as tab-separated value (TSV) file
(which can be used as a input for Microsoft Office Excel and Open Office Calc)
Jump to Target:
In
IDP#
NCBI GI
LOCUS TAG
Search
Page 3 of 60, showing 100 records out of 5973 total, starting on record 201
previous
|
1
|
2
|
3
|
4
|
5
|
6
|
7
|
8
|
9
|
10
|
11
|
12
|
13
|
14
|
15
|
16
|
17
|
18
|
19
|
next
CSGID ID
Priority
stage
Screening
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP91732
(
show subtarget assignments
)
8
selected
No
O67990_VIBMI
0
628
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2Y3U
16.6%
Vibrio mimicus
IDP91733
(
show subtarget assignments
)
8
selected
No
P88946_HHV8
0
449
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2DLL
6.9%
Human herpesvirus
IDP91736
(
show subtarget assignments
)
8
selected
No
Q51451_PSEAE
0
453
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
1R4T
30.7%
Pseudomonas aeruginosa
IDP00564
(
show subtarget assignments
)
1
selected
No
YPO1403
16121683
mukF
condesin subunit F
440
Conserved Gene / Pathway
Phase 2: March 2008
3EUH
84.8%
Yersinia pestis
Cellular processes
Toxin production and resistance
IDP91738
(
show subtarget assignments
)
8
selected
No
Q5YB85_STRSG
0
598
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
1I84
15.1%
Streptococcus sp.
IDP91739
(
show subtarget assignments
)
8
selected
No
Q6V4K9_STRPY
0
310
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2XNX
17.1%
Streptococcus pyogenes
IDP91744
(
show subtarget assignments
)
8
selected
No
Q76ZW2_VACCW
0
190
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
1OYI
39.5%
Vaccinia virus
IDP91745
(
show subtarget assignments
)
8
selected
No
Q846V4_STAAU
0
660
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2A1D
45.6%
Staphylococcus aureus
IDP91747
(
show subtarget assignments
)
8
selected
No
Q8WLQ7_HUMAN
0
79
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
1D5M
94.9%
Homo sapiens
IDP00502
(
show subtarget assignments
)
1
selected
No
YPO2045
16122284
putative hemolysin
1576
Conserved Gene / Pathway
Phase 2: March 2008
3FY3
5.6%
Yersinia pestis
Cellular processes
Toxin production and resistance
IDP91750
(
show subtarget assignments
)
8
selected
No
SPG2_STRSG
0
593
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2KN4
12.1%
Streptococcus sp.
IDP91751
(
show subtarget assignments
)
8
selected
No
STRP_STREQ
0
440
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
1BML
81.1%
Streptococcus dysgalactiae
IDP91753
(
show subtarget assignments
)
8
selected
No
TSST_STAAU
0
234
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2IJ0
82.5%
Staphylococcus aureus
IDP91754
(
show subtarget assignments
)
8
selected
No
TVB1_HUMAN
0
116
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
3UTP
80.2%
Homo sapiens
IDP91758
(
show subtarget assignments
)
8
selected
No
VWF_HUMAN
0
2813
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
1SQ0
7.5%
Homo sapiens
IDP91759
(
show subtarget assignments
)
8
selected
No
XP_001471691
149251757
LOC100044207
PREDICTED: hypothetical protein [Mus mus...
402
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
3E4C
46.3%
Mus musculus
IDP91790
(
show subtarget assignments
)
8
selected
No
ABSDF1465
169633159
LysR family transcriptional regulator [A...
345
drug resistance /
Putative transcriptional regulator of drug efflux pump
Community Requests
3MZ1
36.2%
Acinetobacter baumannii
IDP91799
(
show subtarget assignments
)
8
selected
No
AAL27442
16612079
vanE
VanE [Enterococcus faecalis]
352
drug resistance /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
1E4E
41.5%
Enterococcus faecalis
IDP91806
(
show subtarget assignments
)
8
selected
No
ZP_04520447
237507732
putative polyketide synthase PksJ (PKS) ...
5053
virulence/pathogenesis /
Emerging evidence suggests that natural products from pathogenic organisms are i...
Community Requests
2VSQ
5.6%
Burkholderia pseudomallei
IDP91808
(
show subtarget assignments
)
8
selected
No
AAB07788
924760
CTCF
CTCF [Homo sapiens]
727
innate immunity /
CTCF (CCCTC-binding factor) is an evolutionarily-conserved transcription factor ...
Community Requests
1X6H
10.2%
Homo sapiens
IDP91833
(
show subtarget assignments
)
8
selected
No
SSUSC84_0046
253750968
DNA-binding protein [Streptococcus suis ...
299
Proteins of the ComR family of Rgg regulators are important for horiz...
Community Requests
Streptococcus suis
IDP91834
(
show subtarget assignments
)
8
selected
No
HMPREF9176_0709
312864359
DNA-binding helix-turn-helix protein [St...
300
Proteins of the ComR family of Rgg regulators are important for horiz...
Community Requests
Streptococcus downei
IDP91839
(
show subtarget assignments
)
8
selected
No
Spy49_0415
209558971
mutR
positive transcriptional regulator [Stre...
288
virulence/pathogenesis /
Rgg proteins are peptide-ligand-responsive transcription factors that control vi...
Community Requests
Streptococcus pyogenes
IDP00646
(
show subtarget assignments
)
1
selected
No
SACOL0887
57284346
sei
staphylococcal enterotoxin type I
242
Virulence Associated Factor
Phase 2: March 2008
2G9H
55%
Staphylococcus aureus
Cellular processes
Toxin production and resistance
IDP91841
(
show subtarget assignments
)
8
selected
No
stu0182
55820280
MutR family transcriptional regulator [S...
238
virulence/pathogenesis /
Rgg proteins are peptide-ligand-responsive transcription factors that control vi...
Community Requests
Streptococcus thermophilus
IDP91843
(
show subtarget assignments
)
8
selected
No
Sez_0050
195977202
positive transcriptional regulator, MutR...
287
virulence/pathogenesis /
Rgg proteins are peptide-ligand-responsive transcription factors that control vi...
Community Requests
Streptococcus equi
IDP91848
(
show subtarget assignments
)
8
selected
No
STER_1530
116628259
XRE family transcriptional regulator [St...
287
virulence/pathogenesis /
Rgg proteins are peptide-ligand-responsive transcription factors that control vi...
Community Requests
Streptococcus thermophilus
IDP91849
(
show subtarget assignments
)
8
selected
No
STER_1358
116628108
XRE family transcriptional regulator [St...
286
virulence/pathogenesis /
Rgg proteins are peptide-ligand-responsive transcription factors that control vi...
Community Requests
Streptococcus thermophilus
IDP91852
(
show subtarget assignments
)
8
selected
No
SZO_12400
225868818
DNA-binding protein [Streptococcus equi ...
289
virulence/pathogenesis /
Rgg proteins are peptide-ligand-responsive transcription factors that control vi...
Community Requests
Streptococcus equi
IDP91853
(
show subtarget assignments
)
8
selected
No
SZO_17730
225869330
transcriptional regulator [Streptococcus...
287
virulence/pathogenesis /
Rgg proteins are peptide-ligand-responsive transcription factors that control vi...
Community Requests
Streptococcus equi
IDP91861
(
show subtarget assignments
)
8
selected
No
SDEG_0056
251781503
transcriptional regulator [Streptococcus...
303
Proteins of the ComR family of Rgg regulators are important for horiz...
Community Requests
Streptococcus dysgalactiae
IDP00647
(
show subtarget assignments
)
1
selected
No
SACOL1657
57286179
enterotoxin type A, putative
234
Virulence Associated Factor
Phase 2: March 2008
1ESF
40.2%
Staphylococcus aureus
Cellular processes
Toxin production and resistance
IDP91863
(
show subtarget assignments
)
8
selected
No
STP_0036
333904285
DNA-binding protein [Streptococcus parau...
305
Proteins of the ComR family of Rgg regulators are important for horiz...
Community Requests
Streptococcus parauberis
IDP00431
(
show subtarget assignments
)
1
selected
No
YPO3720
16123858
shlB
hemolysin activator protein
561
Virulence Associated Factor
Phase 2: March 2008
2QDZ
25%
Yersinia pestis
Cellular processes
Toxin production and resistance
IDP00255
(
show subtarget assignments
)
1
selected
No
NP_041725:276-677
9627243
CFA
Cell fusing agent virus Envelope protein...
402
Entry and Cell-Cell Fusion: Contains receptor binding sites and fusogenic domain...
Phase 1: October 2007
3C5X
15.2%
Cell fusing
IDP91867
(
show subtarget assignments
)
8
selected
No
SUB0057
222152254
DNA-binding protein [Streptococcus uberi...
311
Proteins of the ComR family of Rgg regulators are important for horiz...
Community Requests
Streptococcus uberis
IDP91871
(
show subtarget assignments
)
8
selected
No
AAB05624
1209528
vanYB
D,D-carboxypeptidase [Enterococcus faeca...
268
drug resistance /
confers resistance to vancomycin/teicoplanin by hydrolyzing normal cell wall pre...
Community Requests
Enterococcus faecalis
IDP91872
(
show subtarget assignments
)
8
selected
No
ACM47285
222159812
vanYD
D,D-carboxypeptidase VanYD [Enterococcus...
363
drug resistance /
confers resistance to vancomycin/teicoplanin by hydrolyzing normal cell wall pre...
Community Requests
1ES4
24%
Enterococcus faecium
IDP91891
(
show subtarget assignments
)
8
selected
No
SpneCM_010100007700
298255470
putative glutamine-binding protein precu...
254
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
2V25
41.7%
Streptococcus pneumoniae
IDP91892
(
show subtarget assignments
)
8
selected
No
SpneCM_010100009040
298255720
DNA translocase ftsk [Streptococcus pneu...
741
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
2IUT
33.5%
Streptococcus pneumoniae
IDP91894
(
show subtarget assignments
)
8
selected
No
SpneCM_010100007895
298255505
peptidase, M50 family protein [Streptoco...
362
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
Streptococcus pneumoniae
IDP91895
(
show subtarget assignments
)
8
selected
No
SpneCM_010100000537
298254086
YitT family protein [Streptococcus pneum...
313
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
Streptococcus pneumoniae
IDP00265
(
show subtarget assignments
)
1
selected
No
AAA99437_775-1129
323469
N/A
NS1
355
Secreted from infected cells; stimulates protective immune responses (reason for...
Phase 3: June 2008
Dengue virus
host defense modulator
N/A
IDP00514
(
show subtarget assignments
)
1
selected
No
YPO3721
16123859
hemolysin
1635
Conserved Gene / Pathway
Phase 2: March 2008
3FY3
9%
Yersinia pestis
Cellular processes
Toxin production and resistance
IDP91899
(
show subtarget assignments
)
8
selected
No
SpneCM_010100002520
298254473
ABC transporter, ATP-binding/permease pr...
564
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
3QF4
39.1%
Streptococcus pneumoniae
IDP91900
(
show subtarget assignments
)
8
selected
No
SpneCM_010100003670
298254699
ABC transporter, ATP-binding/permease pr...
581
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
3B5X
32.9%
Streptococcus pneumoniae
IDP91904
(
show subtarget assignments
)
8
selected
No
SpneCM_010100000777
298254134
endo-beta-N-acetylglucosaminidase, parti...
573
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
2WW5
20.9%
Streptococcus pneumoniae
IDP91905
(
show subtarget assignments
)
8
selected
No
SpneCM_010100005473
298255048
hypothetical protein SpneCM_05473 [Strep...
158
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
Streptococcus pneumoniae
IDP91907
(
show subtarget assignments
)
8
selected
No
SpneCM_010100004287
298254820
cell division protein DivIB [Streptococc...
406
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
Streptococcus pneumoniae
IDP91908
(
show subtarget assignments
)
8
selected
No
SpneCM_010100007251
298255381
hypothetical protein SpneCM_07251 [Strep...
234
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
Streptococcus pneumoniae
IDP00273
(
show subtarget assignments
)
1
selected
No
AF180817_1476-2094
7329982
N/A
NS3 RNA Helicase
619
Polyprotein processing, RNA replication
Phase 3: June 2008
2WZQ
76.4%
Dengue virus
Transcription
N/A
IDP00274
(
show subtarget assignments
)
1
selected
No
AF180817_2494-3392
7329982
N/A
NS5 methyl transferase and RNA polymeras...
830
RNA-dependent RNA polymerase
Phase 3: June 2008
2J7U
55.5%
Dengue virus
Transcription
N/A
IDP91912
(
show subtarget assignments
)
8
selected
No
SpneCM_010100007064
298255344
hypothetical protein SpneCM_07064 [Strep...
571
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
2XI9
17.3%
Streptococcus pneumoniae
IDP91913
(
show subtarget assignments
)
8
selected
No
SpneCM_010100006539
298255249
cell wall surface anchor family protein ...
334
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
Streptococcus pneumoniae
IDP01752
(
show subtarget assignments
)
1
selected
No
GBAA5282
47778383
nprB
neutral protease B [Bacillus anthracis s...
547
Drug target motif; Conserved; Vaccine Target; Drug target functions
Phase 3: June 2008
1KEI
31.1%
Bacillus anthracis
Protein fate
Degradation of proteins, peptides, and glycopeptides
IDP00278
(
show subtarget assignments
)
1
selected
No
AAA99437_1474-2092
323469
N/A
NS3 RNA Helicase
619
Polyprotein processing, RNA replication
Phase 3: June 2008
2VBC
78.9%
Dengue virus
Transcription
N/A
IDP00279
(
show subtarget assignments
)
1
selected
No
AAA99437_2243-2483
323469
N/A
NS4B
241
possibly RNA replication
Phase 3: June 2008
Dengue virus
Transcription
N/A
IDP02331
(
show subtarget assignments
)
1
selected
No
GBAA2661
47527952
adP-1
alkaline d-peptidase [Bacillus anthracis...
388
Drug target motif; Drug target functions
Phase 3: June 2008
1CEF
30.7%
Bacillus anthracis
Protein fate
Degradation of proteins, peptides, and glycopeptides
IDP02489
(
show subtarget assignments
)
1
selected
No
GBAA3099
47528392
sipU
Signal peptidase I U [Bacillus anthracis...
183
Drug target motif; Drug target functions
Phase 3: June 2008
1T7D
27.8%
Bacillus anthracis
Protein fate
Protein and peptide secretion and trafficking
IDP02671
(
show subtarget assignments
)
1
selected
No
lmo0997
16803037
clpE
ATP-dependent protease [Listeria monocyt...
724
Known virulence-Invasion; PMID:9987121; Presence of Protease Motifs
Phase 3: June 2008
1QVR
46.3%
Listeria monocytogenes
Transport and binding proteins
Unknown substrate
IDP04002
(
show subtarget assignments
)
8
selected
No
CAC05806
12329075
ipgA
IpgA, similarities to IpgE, putative cha...
129
Shigella effector protein
Community Requests
Shigella flexneri
IDP04060
(
show subtarget assignments
)
8
selected
No
CAC05813
12329082
mxiI
MxiI, component of the Mxi-Spa secretion...
97
Shigella effector protein
Community Requests
Shigella flexneri
IDP04117
(
show subtarget assignments
)
8
selected
No
CAC05825
12329094
spa13
spa13, component of the Mxi-Spa secretio...
112
Shigella effector protein
Community Requests
Shigella flexneri
IDP00492
(
show subtarget assignments
)
1
selected
No
YPO1559
16121830
hypothetical protein YPO1559
379
Conserved Gene / Pathway
Phase 2: March 2008
Yersinia pestis
Cellular processes
Toxin production and resistance
IDP04222
(
show subtarget assignments
)
8
selected
No
CAC05827
12329096
spa33
Spa33, component of the Mxi-Spa secretio...
293
Shigella effector protein
Community Requests
Shigella flexneri
IDP04223
(
show subtarget assignments
)
8
selected
No
CAC05808
12329077
ipgD
IpgD, secreted by the Mxi-Spa machinery,...
538
Shigella effector protein
Community Requests
Shigella flexneri
IDP04296
(
show subtarget assignments
)
1
selected
No
YPO2556
218929642
hexA
LysR-family transcriptional regulatory p...
310
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
3ONM
70.6%
Yersinia pestis
Regulatory functions
Other
IDP04306
(
show subtarget assignments
)
8
selected
No
CAC05809
12329078
ipgE
IpgE, cytoplasmic chaperone for IpgD [Sh...
120
Shigella effector protein
Community Requests
1K3S
27.5%
Shigella flexneri
IDP04381
(
show subtarget assignments
)
8
selected
No
CAC05791
12329060
unnamed protein product [Shigella flexne...
296
Shigella effector protein
Community Requests
3MKL
8.4%
Shigella flexneri
IDP04414
(
show subtarget assignments
)
8
selected
No
CAC05786
12329055
sepA
SepA, extracellular serine protease of t...
1364
Shigella effector protein
Community Requests
1WXR
34.9%
Shigella flexneri
IDP04534
(
show subtarget assignments
)
8
selected
No
CAC05815
12329084
mxiK
MxiK, putative component of the Mxi-Spa ...
175
Shigella effector protein
Community Requests
Shigella flexneri
IDP04535
(
show subtarget assignments
)
8
selected
No
CAC05816
12329085
mxiN
MxiN, putative component of the Mxi-Spa ...
231
Shigella effector protein
Community Requests
Shigella flexneri
IDP04537
(
show subtarget assignments
)
8
selected
No
CAC05780
12329049
virF
VirF, member of the AraC family of trans...
262
Shigella effector protein
Community Requests
3GBG
26.3%
Shigella flexneri
IDP04558
(
show subtarget assignments
)
8
selected
No
CAC05811
12329080
mxiG
MxiG, component of the Mxi-Spa secretion...
371
Shigella effector protein
Community Requests
4A4Y
34%
Shigella flexneri
IDP04710
(
show subtarget assignments
)
1
selected
No
YPO0510
115346319
hypothetical protein [Yersinia pestis CO...
367
virulence factor; conserved gene;
Phase 4: April 2009
2XT2
14.7%
Yersinia pestis
Unknown function
General
IDP04725
(
show subtarget assignments
)
1
selected
No
YPO1467
115347221
conserved hypothetical protein [Yersinia...
450
virulence factor;
Phase 4: April 2009
Yersinia pestis
Hypothetical proteins
Conserved
IDP05285
(
show subtarget assignments
)
1
selected
No
CD0663
126698240
tcdA
toxin A [Clostridium difficile 630]
2710
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3SRZ
20%
Clostridium difficile
Cellular processes: Pathogenesis
IDP05371
(
show subtarget assignments
)
1
selected
No
BA_3601
30258129
conserved repeat domain protein [Bacillu...
2358
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Unknown function: General
IDP05752
(
show subtarget assignments
)
1
selected
No
lmo0435
16802479
-
peptidoglycan binding protein [Listeria ...
2013
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Listeria monocytogenes
Unclassified: Role category not yet assigned
IDP90170
(
show subtarget assignments
)
8
selected
No
AAM13458.1
20152997
CPXV011 CDS
CPXV011 protein
658
ankyrin repeat protein
Community Requests
Cowpox virus
conserved hypothetical proteins
0
IDP90220
(
show subtarget assignments
)
8
selected
No
MYXV_gp153
9633785
m150R
m150R
494
ankyrin-like protein, myxoma nuclear factor
Community Requests
Myxoma virus
host range factor
0
IDP90226
(
show subtarget assignments
)
1
selected
No
VC2428
9657003
conserved hypothetical protein [Vibrio c...
246
Conserved gene clusters with virulence associated genes. Conserved Protein; Pred...
January 2009
2OEZ
74.8%
Vibrio cholerae
IDP90274
(
show subtarget assignments
)
8
selected
No
TGME49_015260
211968509
carbamoyl phosphate synthetase II [Toxop...
1699
Mutation of the rate-limiting enzyme carbamoyl phosphate synthetase II (CPSII) d...
Community Requests
1A9X
27.1%
Toxoplasma gondii
IDP90280
(
show subtarget assignments
)
8
selected
No
TGME49_004420
211965378
oocyst wall protein COWP, putative [Toxo...
499
Unpublished data from a differentiation mutagenesis screen indicate that the ooc...
Community Requests
1N7D
19%
Toxoplasma gondii
IDP90298
(
show subtarget assignments
)
8
selected
No
TGME49_120190
211967550
bradyzoite-specific surface protein, put...
398
TgSRS9 is one of the few in the SAG1 family that is expressed only in bradyzoite...
Community Requests
2JKS
37.7%
Toxoplasma gondii
IDP90299
(
show subtarget assignments
)
8
selected
No
TGME49_007160
211969665
Toxoplasma gondii bradyzoite SAG2 relate...
364
The Toxoplasma gondii surface is dominated by a large class of GPI-anchored prot...
Community Requests
2JKS
14%
Toxoplasma gondii
IDP90616
(
show subtarget assignments
)
8
selected
No
VC1054
15641067
DNA polymerase III subunits gamma and ta...
692
Predicted Essential
Community Requests
1JR3
34.5%
Vibrio cholerae
IDP90627
(
show subtarget assignments
)
8
selected
No
VC1239
15641252
cobU
adenosylcobinamide kinase/adenosylcobina...
179
Predicted Essential
Community Requests
1C9K
41.3%
Vibrio cholerae
IDP90773
(
show subtarget assignments
)
8
selected
No
VC2108
15642108
erythronate-4-phosphate dehydrogenase [V...
387
Predicted Essential
Community Requests
3OET
48.3%
Vibrio cholerae
IDP90803
(
show subtarget assignments
)
8
selected
No
YPO0055
16120408
kdtA
3-deoxy-D-manno-octulosonic-acid transfe...
425
Predicted Essential
Community Requests
2XCI
25.2%
Yersinia pestis
IDP90815
(
show subtarget assignments
)
8
selected
No
S2169
30063443
cobT
nicotinate-nucleotide--dimethylbenzimida...
359
Predicted Essential
Community Requests
1JH8
76%
Shigella flexneri
IDP90825
(
show subtarget assignments
)
8
selected
No
S3674
30064729
rpoC
DNA-directed RNA polymerase subunit beta...
1407
Predicted Essential
Community Requests
3IYD
100%
Shigella flexneri
IDP90837
(
show subtarget assignments
)
8
selected
No
S2226
30063491
rfbD
dTDP-4-dehydrorhamnose reductase [Shigel...
299
Predicted Essential
Community Requests
1KBZ
85.6%
Shigella flexneri
IDP90842
(
show subtarget assignments
)
8
selected
No
S0108
30061675
nadC
quinolinate phosphoribosyltransferase [S...
297
Predicted Essential
Community Requests
1QAP
85.9%
Shigella flexneri
IDP90876
(
show subtarget assignments
)
8
selected
No
VC0320
15640347
pantothenate kinase [Vibrio cholerae O1 ...
375
Predicted Essential
Community Requests
1ESM
53.3%
Vibrio cholerae
IDP90968
(
show subtarget assignments
)
8
selected
No
427
Planet Biotechnology company is currently developing an anthrax anti-toxin with ...
Community Requests
1HZH
62.3%
synthetic construct
IDP00733
(
show subtarget assignments
)
1
selected
No
SACOL2419
57285149
hlgA
gamma-hemolysin, component A
309
Conserved Gene / Pathway
Phase 2: March 2008
2QK7
90.9%
Staphylococcus aureus
Cellular processes
Toxin production and resistance
IDP90973
(
show subtarget assignments
)
8
selected
No
AND4_00045
163803697
RTX toxin RtxA [Vibrio sp. AND4]
525
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Vibrio sp.
IDP91921
(
show subtarget assignments
)
8
selected
No
SpneCM_010100000547
298254088
choline binding protein PcpA, partial [S...
222
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
2V04
44.6%
Streptococcus pneumoniae
IDP91920
(
show subtarget assignments
)
8
selected
No
SpneCM_010100000782
298254135
Spn1 transposase, partial [Streptococcus...
145
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
Streptococcus pneumoniae
previous
|
1
|
2
|
3
|
4
|
5
|
6
|
7
|
8
|
9
|
10
|
11
|
12
|
13
|
14
|
15
|
16
|
17
|
18
|
19
|
next
Filter Columns
Filter Columns:
Target Id
Locus Tag
Priority
Stage
Has Screening
Ncbi Gi
Gene Name
Common Name
Length
Justification
Project
Homolog Pdb Id
Homolog Sequence Identity
Organism
Tigr Main Role
Tigr Sub Role
