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Targets
Filter Targets:
Selection Phase:
No Filter
Community Interest
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM10+
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
[Clostridium] difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
0
1
6
8
Keyword:
Type Keyword
Stage:
No Filter
cloned
crystallized
crystal_structure
diffraction
expressed
in_crystallization_trials
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Screening
No Filter
Yes
No
Remove Filters
Download data as tab-separated value (TSV) file
(which can be used as a input for Microsoft Office Excel and Open Office Calc)
Jump to Target:
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IDP#
NCBI GI
LOCUS TAG
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CSGID ID
Priority
stage
Screening
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP90313
(
show subtarget assignments
)
8
cloned
No
CT_713
3329169
ompB
Outer Membrane Protein Analog [Chlamydia...
340
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90310
(
show subtarget assignments
)
8
expressed
No
CT_716
3329172
hypothetical protein [Chlamydia trachoma...
121
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90318
(
show subtarget assignments
)
8
in_crystallization_trials
No
CT_718
3329174
hypothetical protein [Chlamydia trachoma...
174
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90317
(
show subtarget assignments
)
8
cloned
No
CT_724
3329181
hypothetical protein [Chlamydia trachoma...
174
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90314
(
show subtarget assignments
)
8
soluble
No
CT_733
3329191
hypothetical protein [Chlamydia trachoma...
448
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90311
(
show subtarget assignments
)
8
cloned
No
CT_734
3329192
hypothetical protein [Chlamydia trachoma...
221
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90316
(
show subtarget assignments
)
8
cloned
No
CT_743
3329202
hctA
Histone-Like Developmental Protein [Chla...
125
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90315
(
show subtarget assignments
)
8
cloned
No
CT_744
3329204
CHLTR possible phosphoprotein [Chlamydia...
821
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90319
(
show subtarget assignments
)
8
cloned
No
CT_753
3329214
hypothetical protein [Chlamydia trachoma...
74
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90320
(
show subtarget assignments
)
8
cloned
No
CT_779
3329243
hypothetical protein [Chlamydia trachoma...
229
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90321
(
show subtarget assignments
)
8
in_crystallization_trials
No
CT_795
3329261
hypothetical protein [Chlamydia trachoma...
163
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90322
(
show subtarget assignments
)
8
expressed
No
CT_809
3329276
hypothetical protein [Chlamydia trachoma...
103
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90430
(
show subtarget assignments
)
8
cloned
No
CT_812
3329279
pmpD
Putative Outer Membrane Protein D [Chlam...
1531
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90431
(
show subtarget assignments
)
8
in_crystallization_trials
No
CT_845
3329317
hypothetical protein [Chlamydia trachoma...
92
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90427
(
show subtarget assignments
)
8
cloned
No
CT_847
3329319
hypothetical protein [Chlamydia trachoma...
172
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90433
(
show subtarget assignments
)
8
cloned
No
CT_848
3329320
hypothetical protein [Chlamydia trachoma...
168
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90428
(
show subtarget assignments
)
8
cloned
No
CT_849
3329321
hypothetical protein [Chlamydia trachoma...
159
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90429
(
show subtarget assignments
)
8
cloned
No
CT_860
3329334
hypothetical protein [Chlamydia trachoma...
493
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90426
(
show subtarget assignments
)
8
cloned
No
CT_863
3329337
hypothetical protein [Chlamydia trachoma...
482
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90432
(
show subtarget assignments
)
8
in_crystallization_trials
No
CT_865
3329339
hypothetical protein [Chlamydia trachoma...
329
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90437
(
show subtarget assignments
)
8
cloned
No
CT_869
3329344
pmpE
Putative Outer Membrane Protein E [Chlam...
964
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90434
(
show subtarget assignments
)
8
cloned
No
CT_870
3329345
pmpF
Putative Outer Membrane Protein F [Chlam...
1034
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90435
(
show subtarget assignments
)
8
cloned
No
CT_871
3329346
pmpG
Putative Outer Membrane Protein G [Chlam...
1013
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90436
(
show subtarget assignments
)
8
cloned
No
CT_872
3329347
pmpH
Putative Outer Membrane Protein H [Chlam...
1016
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90331
(
show subtarget assignments
)
8
selected
No
CT_874
3329350
pmpI
Putative Outer Membrane Protein I [Chlam...
878
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP91777
(
show subtarget assignments
)
8
purified
No
AAC33914
3513664
sul1
Sul1 dihydropteroate synthase [Escherich...
279
drug resistance /
Dihydropteroate synthase (sulfonamide resistance)
Community Requests
1EYE
35.1%
Escherichia coli
IDP90332
(
show subtarget assignments
)
8
cloned
No
CT_421.1
3522895
hypothetical protein [Chlamydia trachoma...
53
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90334
(
show subtarget assignments
)
8
cloned
No
CT_421.2
3522896
hypothetical protein [Chlamydia trachoma...
53
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90333
(
show subtarget assignments
)
8
soluble
No
CT_606.1
3522903
hypothetical protein [Chlamydia trachoma...
79
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90335
(
show subtarget assignments
)
8
soluble
No
CT_652.1
3522906
hypothetical protein [Chlamydia trachoma...
59
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90336
(
show subtarget assignments
)
8
cloned
No
CT_849.1
3522913
hypothetical protein [Chlamydia trachoma...
62
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP91595
(
show subtarget assignments
)
8
selected
No
AAC64366
3661463
arr-2
ribosylating transferase ARR-2 [Pseudomo...
150
drug resistance /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
2HW2
51.3%
Pseudomonas aeruginosa
IDP91545
(
show subtarget assignments
)
8
expressed
No
AAC78336
3892237
ereA2
erythromycin esterase [Providencia stuar...
408
drug resistance /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Providencia stuartii
IDP91596
(
show subtarget assignments
)
8
selected
No
AAD02118
4104708
vanXst
D-ala-D-ala dipeptidase [Streptomyces to...
208
drug resistance /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
1R44
62%
Streptomyces toyocaensis
IDP00167
(
show subtarget assignments
)
8
in_pdb
3FZY
Yes
VC1451
4455065
rtxA
RTX toxin RtxA
4545
Virulence
Community Requests
3EEB
4.6%
Vibrio cholerae
Cellular processes
Pathogenesis
IDP91692
(
show subtarget assignments
)
8
selected
No
NP_001093
4501891
ACTN1
alpha-actinin-1 isoform b [Homo sapiens]...
892
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
1SJJ
93.3%
Homo sapiens
IDP91693
(
show subtarget assignments
)
8
selected
No
NP_001624
4502067
AMBP
protein AMBP preproprotein [Homo sapiens...
352
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
3QKG
51.7%
Homo sapiens
IDP91689
(
show subtarget assignments
)
8
selected
No
NP_000706
4502503
C4BPA
C4b-binding protein alpha chain precurso...
597
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2GSX
28.8%
Homo sapiens
IDP91703
(
show subtarget assignments
)
8
selected
No
NP_003630
4504631
IKBKG
NF-kappa-B essential modulator isoform a...
419
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
3CL3
29.4%
Homo sapiens
IDP91697
(
show subtarget assignments
)
8
selected
No
NP_002341
4505055
LYN
tyrosine-protein kinase Lyn isoform A [H...
512
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2C0I
66.6%
Homo sapiens
IDP91687
(
show subtarget assignments
)
8
selected
No
NP_000292
4505881
PLG
plasminogen isoform 1 precursor [Homo sa...
810
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
4DUR
97.7%
Homo sapiens
IDP91699
(
show subtarget assignments
)
8
selected
No
NP_002750
4506103
EIF2AK2
interferon-induced, double-stranded RNA-...
551
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2A19
50.6%
Homo sapiens
IDP91700
(
show subtarget assignments
)
8
selected
No
NP_002791
4506205
PSMB9
proteasome subunit beta type-9 proprotei...
219
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
3UNF
82.2%
Homo sapiens
IDP91661
(
show subtarget assignments
)
8
selected
No
NP_002980
4506835
CCL21
C-C motif chemokine 21 precursor [Homo s...
134
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2L4N
82.8%
Homo sapiens
IDP91048
(
show subtarget assignments
)
8
in_crystallization_trials
No
EGA0001
4545123
vanT
serine racemase VanT [Enterococcus galli...
698
drug resistance /
Serine racemase involved in synthesis of D-Ala-D-Ser, a component of vancomycin ...
Community Requests
4ECL
22.3%
Enterococcus gallinarum
IDP91705
(
show subtarget assignments
)
8
selected
No
NP_004879
4757818
ATP6V1G1
V-type proton ATPase subunit G 1 [Homo s...
118
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2K88
27.1%
Homo sapiens
IDP91662
(
show subtarget assignments
)
8
selected
No
NP_004351
4757960
CDH1
cadherin-1 preproprotein [Homo sapiens]
882
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
1Q55
57.5%
Homo sapiens
IDP91704
(
show subtarget assignments
)
8
selected
No
NP_004528
4758756
NAP1L1
nucleosome assembly protein 1-like 1 [Ho...
391
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2AYU
35%
Homo sapiens
IDP91707
(
show subtarget assignments
)
8
selected
No
NP_005447
4885433
MAPK8IP1
C-Jun-amino-terminal kinase-interacting ...
711
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2FPF
9.8%
Homo sapiens
IDP91706
(
show subtarget assignments
)
8
selected
No
NP_005410
4885615
STAT2
signal transducer and activator of trans...
851
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
1YVL
36%
Homo sapiens
IDP91709
(
show subtarget assignments
)
8
selected
No
NP_006107
5174703
TAB1
TGF-beta-activated kinase 1 and MAP3K7-b...
504
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2J4O
79.6%
Homo sapiens
IDP91047
(
show subtarget assignments
)
8
in_crystallization_trials
No
EFA0003
5353563
vanRD
response regulator [Enterococcus faecium...
232
drug resistance /
Component of regulatory system of transcription of vancomycin resistance genes
Community Requests
2GWR
37.1%
Enterococcus faecium
IDP91712
(
show subtarget assignments
)
8
selected
No
NP_006588
5729877
HSPA8
heat shock cognate 71 kDa protein isofor...
646
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
3C7N
85.8%
Homo sapiens
IDP91711
(
show subtarget assignments
)
8
selected
No
NP_006550
5730027
KHDRBS1
KH domain-containing, RNA-binding, signa...
443
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2BL5
14.7%
Homo sapiens
IDP91714
(
show subtarget assignments
)
8
selected
No
NP_006734
5803137
RBM3
putative RNA-binding protein 3 [Homo sap...
157
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
1X5S
41.4%
Homo sapiens
IDP04695
(
show subtarget assignments
)
1
expressed
No
YPCD1.01
5832424
YPCD1.01
putative transposase [Yersinia pestis CO...
340
virulence factor; putative drug target function;
Phase 4: April 2009
Yersinia pestis
Mobile and extrachromosomal element functions
Transposon functions
IDP04061
(
show subtarget assignments
)
1
cloned
No
YPCD1.07
5832430
YPCD1.07
hypothetical protein YPCD1.07 [Yersinia ...
98
virulence factor;
Phase 4: April 2009
Yersinia pestis
Hypothetical proteins
Conserved
IDP04288
(
show subtarget assignments
)
1
expressed
No
YPCD1.08c
5832431
YPCD1.08c
hypothetical protein YPCD1.08c [Yersinia...
99
virulence factor; conserved gene;
Phase 4: April 2009
3KXE
28.3%
Yersinia pestis
IDP04078
(
show subtarget assignments
)
1
expressed
No
YPCD1.09c
5832432
YPCD1.09c
hypothetical protein YPCD1.09c [Yersinia...
91
virulence factor; conserved gene;
Phase 4: April 2009
3KXE
29.7%
Yersinia pestis
Hypothetical proteins
Conserved
IDP04696
(
show subtarget assignments
)
1
cloned
No
YPCD1.15c
5832437
YPCD1.15c
hypothetical protein YPCD1.15c [Yersinia...
152
virulence factor; conserved gene; putative drug target function;
Phase 4: April 2009
Yersinia pestis
Mobile and extrachromosomal element functions
Transposon functions
IDP04041
(
show subtarget assignments
)
1
cloned
No
YPCD1.16c
5832438
YPCD1.16c
hypothetical protein YPCD1.16c [Yersinia...
107
virulence factor; conserved gene; putative drug target function;
Phase 4: April 2009
Yersinia pestis
Mobile and extrachromosomal element functions
Transposon functions
IDP04118
(
show subtarget assignments
)
1
cloned
No
YPCD1.22c
5832443
YPCD1.22c
hypothetical protein YPCD1.22c [Yersinia...
129
virulence factor; conserved gene;
Phase 4: April 2009
Yersinia pestis
Hypothetical proteins
Conserved
IDP04273
(
show subtarget assignments
)
1
cloned
No
YPCD1.23
5832444
YPCD1.23
hypothetical protein YPCD1.23 [Yersinia ...
139
virulence factor; conserved gene;
Phase 4: April 2009
Yersinia pestis
Hypothetical proteins
Conserved
IDP04354
(
show subtarget assignments
)
1
expressed
No
YPCD1.44
5832464
YPCD1.44
putative Yop secretion membrane protein ...
217
virulence factor; conserved gene; putative drug target function;
Phase 4: April 2009
Yersinia pestis
Cell envelope
Surface structures
IDP04098
(
show subtarget assignments
)
1
cloned
No
YPCD1.50
5832470
YPCD1.50
hypothetical protein YPCD1.50 [Yersinia ...
32
virulence factor; conserved gene;
Phase 4: April 2009
Yersinia pestis
IDP04038
(
show subtarget assignments
)
1
expressed
No
YPCD1.65
5832485
YPCD1.65
putative transposase [Yersinia pestis CO...
102
virulence factor; conserved gene;
Phase 4: April 2009
Yersinia pestis
IDP04314
(
show subtarget assignments
)
1
purified
No
YPCD1.73c
5832493
YPCD1.73c
hypothetical protein YPCD1.73c [Yersinia...
149
virulence factor; conserved gene;
Phase 4: April 2009
1JSC
40.7%
Yersinia pestis
IDP04047
(
show subtarget assignments
)
1
cloned
No
YPCD1.92
5832507
YPCD1.92
hypothetical protein YPCD1.92 [Yersinia ...
109
virulence factor; conserved gene;
Phase 4: April 2009
Yersinia pestis
Hypothetical proteins
Conserved
IDP04315
(
show subtarget assignments
)
1
expressed
No
YPCD1.93
5832508
YPCD1.93
putative transposase [Yersinia pestis CO...
88
virulence factor; conserved gene; putative drug target function;
Phase 4: April 2009
Yersinia pestis
Mobile and extrachromosomal element functions
Transposon functions
IDP04353
(
show subtarget assignments
)
1
expressed
No
YPCD1.96c
5832511
YPCD1.96c
putative transposase [Yersinia pestis CO...
143
drug target; virulence factor; conserved gene; putative drug target function;...
Phase 4: April 2009
Yersinia pestis
Mobile and extrachromosomal element functions
Transposon functions
IDP04436
(
show subtarget assignments
)
1
expressed
No
YPCD1.97c
5832512
YPCD1.97c
putative transposase [Yersinia pestis CO...
308
virulence factor; conserved gene;
Phase 4: April 2009
Yersinia pestis
IDP91789
(
show subtarget assignments
)
8
purified
No
TETS_LISMO
6094462
RecName: Full=Tetracycline resistance pr...
641
drug resistance /
Tetracycline resistance
Community Requests
1DAR
27.6%
Listeria monocytogenes
IDP91716
(
show subtarget assignments
)
8
selected
No
NP_009330
6274552
STAT1
signal transducer and activator of trans...
750
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
1YVL
91.1%
Homo sapiens
IDP90337
(
show subtarget assignments
)
8
expressed
No
CT_623
6578109
CHLPN 76kDa Homolog [Chlamydia trachomat...
432
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90340
(
show subtarget assignments
)
8
expressed
No
CT_696
6578111
hypothetical protein [Chlamydia trachoma...
392
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP05748
(
show subtarget assignments
)
1
cloned
No
Cj0435
6967908
fabG
phosphoglycerate mutase [Campylobacter j...
247
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
2P68
48.8%
Campylobacter jejuni
Fatty acid and phospholipid metabolism: Biosynthesis
IDP05649
(
show subtarget assignments
)
1
expressed
No
Cj0464
6967934
recG
zinc protease-like protein [Campylobacte...
607
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
1GM5
28.8%
Campylobacter jejuni
DNA metabolism: DNA replication, recombination, and repair
IDP05542
(
show subtarget assignments
)
1
cloned
No
Cj0508
6967973
pbpA
hypothetical protein Cj0504c [Campylobac...
643
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
3FWL
31.1%
Campylobacter jejuni
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
IDP05650
(
show subtarget assignments
)
1
soluble
No
Cj0543
6968007
proS
hypothetical protein Cj0539 [Campylobact...
569
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
2J3L
42.8%
Campylobacter jejuni
Protein synthesis: tRNA aminoacylation
IDP05073
(
show subtarget assignments
)
1
expressed
No
Cj0562
6968026
dnaB
gamma-glutamyl phosphate reductase [Camp...
439
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
2VYE
37.1%
Campylobacter jejuni
DNA metabolism: DNA replication, recombination, and repair
IDP05749
(
show subtarget assignments
)
1
cloned
No
Cj0775c
6968216
valS
putative periplasmic protein [Campylobac...
870
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
1GAX
38.2%
Campylobacter jejuni
Protein synthesis: tRNA aminoacylation
IDP05336
(
show subtarget assignments
)
1
soluble
No
Cj0799c
6968240
ruvA
hypothetical protein Cj0794 [Campylobact...
183
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
1IXR
32.5%
Campylobacter jejuni
DNA metabolism: DNA replication, recombination, and repair
IDP91080
(
show subtarget assignments
)
8
cloned
No
Cj0803
6968244
msbA
lipid export ABC transport protein
580
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
2HYD
31.6%
Campylobacter jejuni
IDP00066
(
show subtarget assignments
)
1
expressed
No
NTL01CJ00766
6968259
kdsB
3-deoxy-manno-octulosonate cytidylyltran...
239
These targets are similar to actual drug targets and will be used mostly for coc...
Phase 1: October 2007
2Y6P
40.2%
Campylobacter jejuni
Protein synthesis
tRNA aminoacylation
IDP05545
(
show subtarget assignments
)
1
cloned
No
Cj0845c
6968286
gltX
putative fructose-1,6-bisphosphatase [Ca...
431
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
2O5R
33.8%
Campylobacter jejuni
Protein synthesis: tRNA aminoacylation
IDP05220
(
show subtarget assignments
)
1
cloned
No
Cj1101
6968529
-
putative integral membrane protein [Camp...
670
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
1PJR
36.6%
Campylobacter jejuni
DNA metabolism: DNA replication, recombination, and repair
IDP01740
(
show subtarget assignments
)
1
cloned
No
Cj1140
6968568
htrB
putative lipid A biosynthesis lauroyl ac...
295
Known Predicted virulence-LOS-Immune evasion and molecular mimcry; PMID:15578098...
Phase 3: June 2008
Campylobacter jejuni
Cell envelope
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
IDP05651
(
show subtarget assignments
)
1
soluble
No
Cj1183c
6968610
cfa
guanylate kinase [Campylobacter jejuni s...
387
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
1KP9
27.9%
Campylobacter jejuni
Fatty acid and phospholipid metabolism: Biosynthesis
IDP00067
(
show subtarget assignments
)
1
in_pdb
3PFI
No
NT01CJ1369
6968796
ruvB
holliday junction DNA helicase [Campylob...
335
These targets are similar to actual drug targets and will be used mostly for coc...
Phase 1: October 2007
3PFI
100%
Campylobacter jejuni
Biosynthesis of cofactors, prosthetic groups, and carriers
Riboflavin, FMN, and FAD
IDP05544
(
show subtarget assignments
)
1
purified
No
Cj1409
6968828
acpS
putative Ni/Fe-hydrogenase small subunit...
115
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
3HYK
39.5%
Campylobacter jejuni
Fatty acid and phospholipid metabolism: Biosynthesis
IDP02204
(
show subtarget assignments
)
1
cloned
No
Cj1462
6968880
Cj1452
putative integral membrane protein [Camp...
237
Known Predicted virulence-flagella; PMID:8478066
Phase 3: June 2008
Campylobacter jejuni
Cell envelope
Other
IDP91535
(
show subtarget assignments
)
8
selected
No
TC_0052
7190091
ompA
major outer membrane protein, porin [Chl...
387
vaccine candidate /
Vaccine formulation
Community Requests
Chlamydia muridarum
IDP91533
(
show subtarget assignments
)
8
selected
No
TC_0727
7190756
omcB
OmcB [Chlamydia muridarum Nigg]
554
vaccine candidate /
Vaccine formulation
Community Requests
Chlamydia muridarum
IDP91532
(
show subtarget assignments
)
8
selected
No
TC_0728
7190757
omcA
OmcA [Chlamydia muridarum Nigg]
88
vaccine candidate /
Vaccine formulation
Community Requests
Chlamydia muridarum
IDP00274
(
show subtarget assignments
)
1
selected
No
AF180817_2494-3392
7329982
N/A
NS5 methyl transferase and RNA polymeras...
830
RNA-dependent RNA polymerase
Phase 3: June 2008
2J7U
55.5%
Dengue virus
Transcription
N/A
IDP00273
(
show subtarget assignments
)
1
selected
No
AF180817_1476-2094
7329982
N/A
NS3 RNA Helicase
619
Polyprotein processing, RNA replication
Phase 3: June 2008
2WZQ
76.4%
Dengue virus
Transcription
N/A
IDP00272
(
show subtarget assignments
)
1
in_pdb
3EGP
3IRC
No
AF180817_281-775
7329982
N/A
Envelope (E)
495
Contains receptor binding sites and fusogenic domain; also contains 12 Cys resid...
Phase 1: October 2007
3G7T
78.8%
Dengue virus
N/A
IDP00271
(
show subtarget assignments
)
1
expressed
No
AF180817_115-280
7329982
N/A
Premembrane/Membrane protein (prM)
166
Very hydrophilic; 6 Cys residues form intramolecular disulfide bonds
Phase 3: June 2008
3C5X
59.6%
Dengue virus
N/A
IDP00270
(
show subtarget assignments
)
1
cloned
No
AF180817_2245-2493
7329982
N/A
NS4B
249
possibly RNA replication
Phase 3: June 2008
Dengue virus
Transcription
N/A
IDP00269
(
show subtarget assignments
)
1
cloned
No
AF180817_776-1127
7329982
N/A
NS1
352
Secreted from infected cells; stimulates protective immune responses (reason for...
Phase 3: June 2008
Dengue virus
host defense modulator
N/A
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