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Targets
Filter Targets:
Selection Phase:
No Filter
Community Interest
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM10+
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
[Clostridium] difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
0
1
6
8
Keyword:
Type Keyword
Stage:
No Filter
cloned
crystallized
crystal_structure
diffraction
expressed
in_crystallization_trials
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Screening
No Filter
Yes
No
Remove Filters
Download data as tab-separated value (TSV) file
(which can be used as a input for Microsoft Office Excel and Open Office Calc)
Jump to Target:
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IDP#
NCBI GI
LOCUS TAG
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Page 5 of 60, showing 100 records out of 5973 total, starting on record 401
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CSGID ID
Priority
stage
Screening
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP91925
(
show subtarget assignments
)
8
selected
No
SpneCM_010100003175
298254600
prfC
peptide chain release factor 3 [Streptoc...
514
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
3TR5
48.1%
Streptococcus pneumoniae
IDP91926
(
show subtarget assignments
)
8
selected
No
SpneCM_010100003840
298254733
scpB
segregation and condensation protein B [...
189
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
2Z99
29.6%
Streptococcus pneumoniae
IDP91929
(
show subtarget assignments
)
8
selected
No
SpneCM_010100004422
298254845
formate acetyltransferase [Streptococcus...
774
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
1H16
43.6%
Streptococcus pneumoniae
IDP91930
(
show subtarget assignments
)
8
selected
No
SPH_0573
169834046
hypothetical protein SPH_0573 [Streptoco...
128
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
Streptococcus pneumoniae
IDP91933
(
show subtarget assignments
)
8
selected
No
SpneCM_010100001964
298254365
VicX protein [Streptococcus pneumoniae s...
269
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
Streptococcus pneumoniae
IDP91934
(
show subtarget assignments
)
8
selected
No
SpneCM_010100000482
298254075
hypothetical protein SpneCM_00482 [Strep...
92
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
Streptococcus pneumoniae
IDP91938
(
show subtarget assignments
)
8
selected
No
SpneCM_010100009513
298255813
cell division ABC transporter, permease ...
308
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
Streptococcus pneumoniae
IDP91939
(
show subtarget assignments
)
8
selected
No
SpneCM_010100003755
298254716
cation diffusion facilitator transporter...
296
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
2QFI
15.9%
Streptococcus pneumoniae
IDP91941
(
show subtarget assignments
)
8
selected
No
SpneCM_010100000177
298254016
ABC transporter, ATP-binding/permease pr...
588
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
3QF4
38.6%
Streptococcus pneumoniae
IDP91942
(
show subtarget assignments
)
8
selected
No
SpneCM_010100007536
298255438
immunoglobulin A1 protease [Streptococcu...
2004
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
Streptococcus pneumoniae
IDP91945
(
show subtarget assignments
)
8
selected
No
SpneCM_010100006704
298255282
Cps19aC [Streptococcus pneumoniae str. C...
230
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
Streptococcus pneumoniae
IDP91946
(
show subtarget assignments
)
8
selected
No
SpneCM_010100004617
298254882
integral membrane protein [Streptococcus...
317
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
3KMI
12%
Streptococcus pneumoniae
IDP00492
(
show subtarget assignments
)
1
selected
No
YPO1559
16121830
hypothetical protein YPO1559
379
Conserved Gene / Pathway
Phase 2: March 2008
Yersinia pestis
Cellular processes
Toxin production and resistance
IDP91948
(
show subtarget assignments
)
8
selected
No
SpneCM_010100000392
298254057
histidine kinase PnpS [Streptococcus pne...
443
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
3A0R
19.4%
Streptococcus pneumoniae
IDP91969
(
show subtarget assignments
)
8
selected
No
SpneCM_010100009453
298255801
peptidyl-prolyl cis-trans isomerase, cyc...
267
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
2A2N
31.5%
Streptococcus pneumoniae
IDP91973
(
show subtarget assignments
)
8
selected
No
SpneCM_010100000437
298254066
UTP-glucose-1-phosphate uridylyltransfer...
299
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
2UX8
46.2%
Streptococcus pneumoniae
IDP91977
(
show subtarget assignments
)
8
selected
No
SpneCM_010100007810
298255490
D-alanyl-D-alanine carboxypeptidase [Str...
238
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
Streptococcus pneumoniae
IDP91978
(
show subtarget assignments
)
8
selected
No
SpneCM_010100008980
298255708
pneumococcal histidine triad protein D (...
183
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
Streptococcus pneumoniae
IDP91981
(
show subtarget assignments
)
8
selected
No
SpneCM_010100000172
298254015
serine protease [Streptococcus pneumonia...
2143
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
3AFG
5.5%
Streptococcus pneumoniae
IDP91982
(
show subtarget assignments
)
8
selected
No
SpneCM_010100007575
298255445
LysM domain protein [Streptococcus pneum...
195
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
Streptococcus pneumoniae
IDP91984
(
show subtarget assignments
)
8
selected
No
SpneCM_010100008317
298255584
spfh domain/band 7 family protein [Strep...
299
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
3BK6
17.1%
Streptococcus pneumoniae
IDP91990
(
show subtarget assignments
)
8
selected
No
SpneCM_010100004332
298254829
ABC transporter substrate-binding protei...
80
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
1XT8
41.2%
Streptococcus pneumoniae
IDP00502
(
show subtarget assignments
)
1
selected
No
YPO2045
16122284
putative hemolysin
1576
Conserved Gene / Pathway
Phase 2: March 2008
3FY3
5.6%
Yersinia pestis
Cellular processes
Toxin production and resistance
IDP91997
(
show subtarget assignments
)
8
selected
No
SpneCM_010100004547
298254868
cell wall surface anchor family protein,...
415
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
Streptococcus pneumoniae
IDP91999
(
show subtarget assignments
)
8
selected
No
SpneCM_010100004482
298254857
BlpC ABC transporter [Streptococcus pneu...
453
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
Streptococcus pneumoniae
IDP00791
(
show subtarget assignments
)
1
selected
No
SACOL1178
57284463
superantigen-like protein
238
Virulence Associated Factor
Phase 2: March 2008
1M4V
23.9%
Staphylococcus aureus
Cellular processes
Toxin production and resistance
IDP92002
(
show subtarget assignments
)
8
selected
No
SpneCM_010100000145
298254010
competence protein CglD [Streptococcus p...
134
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
Streptococcus pneumoniae
IDP92003
(
show subtarget assignments
)
8
selected
No
SpneCM_010100002775
298254522
sensor histidine kinase [Streptococcus p...
350
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
2C2A
22%
Streptococcus pneumoniae
IDP92006
(
show subtarget assignments
)
8
selected
No
FTN_0818
118497410
lipase/esterase [Francisella novicida U1...
306
virulence/pathogenesis /
We have shown that this protein is involved in Francisella virulence in vivo and...
Community Requests
3AIK
33.3%
Francisella novicida
IDP92007
(
show subtarget assignments
)
8
selected
No
FTT_0941c
56708038
unnamed protein product [Francisella tul...
306
virulence/pathogenesis /
We have shown that this protein is involved in Francisella virulence in vivo and...
Community Requests
3AIK
33%
Francisella tularensis
IDP92012
(
show subtarget assignments
)
8
selected
No
TGME49_037830
237845437
DNA polymerase I, putative [Toxoplasma g...
938
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
2BDP
17.4%
Toxoplasma gondii
IDP00646
(
show subtarget assignments
)
1
selected
No
SACOL0887
57284346
sei
staphylococcal enterotoxin type I
242
Virulence Associated Factor
Phase 2: March 2008
2G9H
55%
Staphylococcus aureus
Cellular processes
Toxin production and resistance
IDP92014
(
show subtarget assignments
)
8
selected
No
TGME49_067100
237838983
protein phosphatase 2C, putative [Toxopl...
909
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
2I0O
10.2%
Toxoplasma gondii
IDP92015
(
show subtarget assignments
)
8
selected
No
TGME49_064780
237838619
UDP-N-acetylhexosamine pyrophosphorylase...
900
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1JVD
19.6%
Toxoplasma gondii
IDP00514
(
show subtarget assignments
)
1
selected
No
YPO3721
16123859
hemolysin
1635
Conserved Gene / Pathway
Phase 2: March 2008
3FY3
9%
Yersinia pestis
Cellular processes
Toxin production and resistance
IDP92018
(
show subtarget assignments
)
8
selected
No
TGME49_100260
237844903
threonyl-tRNA synthetase, putative [Toxo...
844
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1QF6
30.7%
Toxoplasma gondii
IDP92020
(
show subtarget assignments
)
8
selected
No
TGME49_120640
237841247
cyclophilin, putative [Toxoplasma gondii...
764
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
2A2N
15.3%
Toxoplasma gondii
IDP92021
(
show subtarget assignments
)
8
selected
No
TGME49_005720
237837011
adenosine/AMP deaminase domain containin...
366
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1A4L
25.7%
Toxoplasma gondii
IDP92025
(
show subtarget assignments
)
8
selected
No
TGME49_016130
237843251
ubiquitin-conjugating enzyme E2, putativ...
227
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
2AAK
46.3%
Toxoplasma gondii
IDP92026
(
show subtarget assignments
)
8
selected
No
TGME49_016450
237843315
proteasome subunit alpha type 3, putativ...
260
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3UNB
41.2%
Toxoplasma gondii
IDP92028
(
show subtarget assignments
)
8
selected
No
TGME49_017740
237844087
oxoacyl-ACP reductase, putative [Toxopla...
376
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
2C07
35.9%
Toxoplasma gondii
IDP92029
(
show subtarget assignments
)
8
selected
No
TGME49_018920
237842737
proteasome subunit beta type 5, putative...
309
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3NZJ
42.7%
Toxoplasma gondii
IDP92032
(
show subtarget assignments
)
8
selected
No
TGME49_019800
237842869
vacuolar ATP synthase subunit B, putativ...
505
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
2C61
53.9%
Toxoplasma gondii
IDP00647
(
show subtarget assignments
)
1
selected
No
SACOL1657
57286179
enterotoxin type A, putative
234
Virulence Associated Factor
Phase 2: March 2008
1ESF
40.2%
Staphylococcus aureus
Cellular processes
Toxin production and resistance
IDP92034
(
show subtarget assignments
)
8
selected
No
TGME49_024900
237833733
adenylate kinase, putative [Toxoplasma g...
257
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3TLX
55.6%
Toxoplasma gondii
IDP92035
(
show subtarget assignments
)
8
selected
No
ABE76515
92399547
tpi1
triose-phosphate isomerase 1 [Toxoplasma...
252
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1MO0
52.4%
Toxoplasma gondii
IDP92042
(
show subtarget assignments
)
8
selected
No
TGME49_040590
237834761
DNA-directed RNA polymerases I, II, and ...
205
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3H0G
44%
Toxoplasma gondii
IDP92043
(
show subtarget assignments
)
8
selected
No
TGME49_040690
237834781
S-adenosylmethionine synthetase, putativ...
415
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
2P02
60.5%
Toxoplasma gondii
IDP92045
(
show subtarget assignments
)
8
selected
No
TGME49_042730
237834991
guanylate kinase, putative [Toxoplasma g...
346
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1LVG
27.5%
Toxoplasma gondii
IDP92046
(
show subtarget assignments
)
8
selected
No
TGME49_007640
211967232
isoleucine-tRNA synthetase, putative [To...
1103
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1ILE
30.6%
Toxoplasma gondii
IDP92049
(
show subtarget assignments
)
8
selected
No
TGME49_049590
237835989
proteasome subunit alpha type 5, putativ...
258
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3UNB
57.4%
Toxoplasma gondii
IDP92050
(
show subtarget assignments
)
8
selected
No
TGME49_049950
237836059
MAK16 protein, putative [Toxoplasma gond...
333
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
Toxoplasma gondii
IDP92052
(
show subtarget assignments
)
8
selected
No
TGME49_053800
237840277
ribosomal protein L15, putative [Toxopla...
287
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
Toxoplasma gondii
IDP92053
(
show subtarget assignments
)
8
selected
No
TGME49_054900
237840493
proteasome subunit beta type 2, putative...
191
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1IRU
49%
Toxoplasma gondii
IDP92057
(
show subtarget assignments
)
8
selected
No
TGME49_061030
237831917
mitochondrial NADPH:adrenodoxin oxidored...
656
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1CJC
25%
Toxoplasma gondii
IDP92058
(
show subtarget assignments
)
8
selected
No
ACN59873
224590780
prex
plastid replication-repair enzyme [Toxop...
2579
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1D8Y
7.2%
Toxoplasma gondii
IDP92060
(
show subtarget assignments
)
8
selected
No
TGME49_063190
237832243
adenylosuccinate lyase, putative [Toxopl...
500
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
2PTS
43.2%
Toxoplasma gondii
IDP92061
(
show subtarget assignments
)
8
selected
No
TGME49_063490
237832303
ubiquitin-conjugating enzyme E2, putativ...
163
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1JAS
52.8%
Toxoplasma gondii
IDP92064
(
show subtarget assignments
)
8
selected
No
AAT47115
48857019
putative thioredoxin peroxidase TPX1/2 [...
333
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
2P5Q
18.6%
Toxoplasma gondii
IDP92065
(
show subtarget assignments
)
8
selected
No
TGME49_067390
237839019
DNA-directed RNA polymerases I and III s...
346
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3H0G
25.1%
Toxoplasma gondii
IDP92067
(
show subtarget assignments
)
8
selected
No
TGME49_069430
237832673
hexaprenyl pyrophosphate synthetase prot...
536
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3APZ
23.9%
Toxoplasma gondii
IDP92068
(
show subtarget assignments
)
8
selected
No
TGME49_078050
237842421
proteasome subunit alpha type 1, putativ...
247
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3UNB
50.6%
Toxoplasma gondii
IDP92073
(
show subtarget assignments
)
8
selected
No
TGME49_088860
237838049
ruvB-like 2 protein, putative [Toxoplasm...
508
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
2XSZ
49.2%
Toxoplasma gondii
IDP92074
(
show subtarget assignments
)
8
selected
No
TGME49_095350
237844373
nucleoside diphosphate kinase, putative ...
155
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1NDL
66.5%
Toxoplasma gondii
IDP92076
(
show subtarget assignments
)
8
selected
No
TGME49_097060
237843677
phosphoglycerate mutase 1, putative [Tox...
265
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1XQ9
70.2%
Toxoplasma gondii
IDP92077
(
show subtarget assignments
)
8
selected
No
TGME49_097370
237843739
ruvB-like 1, putative [Toxoplasma gondii...
463
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
2C9O
62.9%
Toxoplasma gondii
IDP92080
(
show subtarget assignments
)
8
selected
No
TGME49_105290
237842049
vacuolar ATP synthase subunit E, putativ...
236
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
2DM9
25%
Toxoplasma gondii
IDP92081
(
show subtarget assignments
)
8
selected
No
TGME49_106970
237845145
thymidylate kinase, putative [Toxoplasma...
273
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1E2D
35.2%
Toxoplasma gondii
IDP92083
(
show subtarget assignments
)
8
selected
No
TGME49_109210
237829785
peroxidoxin 2 [Toxoplasma gondii ME49]
224
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1PRX
54%
Toxoplasma gondii
IDP92084
(
show subtarget assignments
)
8
selected
No
TGME49_112250
237830299
DNA-directed RNA polymerase III subunit,...
106
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3QT1
41.3%
Toxoplasma gondii
IDP00255
(
show subtarget assignments
)
1
selected
No
NP_041725:276-677
9627243
CFA
Cell fusing agent virus Envelope protein...
402
Entry and Cell-Cell Fusion: Contains receptor binding sites and fusogenic domain...
Phase 1: October 2007
3C5X
15.2%
Cell fusing
IDP92088
(
show subtarget assignments
)
8
selected
No
TGME49_118230
237840929
phosphoglycerate kinase, putative [Toxop...
417
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1LTK
60.9%
Toxoplasma gondii
IDP92090
(
show subtarget assignments
)
8
selected
No
TGME49_121570
237844801
(3R)-hydroxymyristoyl ACP dehydrase, put...
231
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1Z6B
35.9%
Toxoplasma gondii
IDP92091
(
show subtarget assignments
)
8
selected
No
TGME49_014210
237842913
centromere/microtubule binding protein, ...
505
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3U28
49.9%
Toxoplasma gondii
IDP92094
(
show subtarget assignments
)
8
selected
No
TGME49_038190
237834427
DNA-directed RNA polymerase II, putative...
484
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1I3Q
20.7%
Toxoplasma gondii
IDP92095
(
show subtarget assignments
)
8
selected
No
TGME49_046920
237835543
glutathione reductase, putative [Toxopla...
483
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1GER
46.2%
Toxoplasma gondii
IDP92097
(
show subtarget assignments
)
8
selected
No
TGME49_086210
237839921
serine/threonine protein phosphatase, pu...
338
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
2IE3
57.4%
Toxoplasma gondii
IDP92098
(
show subtarget assignments
)
8
selected
No
TGME49_090670
211966125
cytosol aminopeptidase [Toxoplasma gondi...
563
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3KQX
41.2%
Toxoplasma gondii
IDP02185
(
show subtarget assignments
)
1
selected
No
FTT0408
56707557
gcvH
glycine cleavage system H protein [Franc...
127
Drug Target
Phase 3: June 2008
3A7A
59.8%
Francisella tularensis
Energy metabolism
Amino acids and amines
IDP92104
(
show subtarget assignments
)
8
selected
No
TGME49_026400
237833991
lipoic acid synthase [Toxoplasma gondii ...
543
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
Toxoplasma gondii
IDP92106
(
show subtarget assignments
)
8
selected
No
TGME49_079450
237845375
adenylosuccinate synthetase, putative [T...
460
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1P9B
48.7%
Toxoplasma gondii
IDP92107
(
show subtarget assignments
)
8
selected
No
TGME49_091640
237838437
aspartate carbamoyltransferase [Toxoplas...
423
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1AT1
30.5%
Toxoplasma gondii
IDP92110
(
show subtarget assignments
)
8
selected
No
TGME49_001380
237836313
chorismate synthase, putative [Toxoplasm...
536
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1R52
36.9%
Toxoplasma gondii
IDP92111
(
show subtarget assignments
)
8
selected
No
TGME49_015280
237843099
iron-sulfur subunit of succinate dehydro...
342
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1ZOY
45%
Toxoplasma gondii
IDP00564
(
show subtarget assignments
)
1
selected
No
YPO1403
16121683
mukF
condesin subunit F
440
Conserved Gene / Pathway
Phase 2: March 2008
3EUH
84.8%
Yersinia pestis
Cellular processes
Toxin production and resistance
IDP92113
(
show subtarget assignments
)
8
selected
No
TGME49_118590
237841001
mrp protein, putative [Toxoplasma gondii...
644
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3KB1
14%
Toxoplasma gondii
IDP00265
(
show subtarget assignments
)
1
selected
No
AAA99437_775-1129
323469
N/A
NS1
355
Secreted from infected cells; stimulates protective immune responses (reason for...
Phase 3: June 2008
Dengue virus
host defense modulator
N/A
IDP92117
(
show subtarget assignments
)
8
selected
No
TGME49_073410
237833291
tyrosyl-tRNA synthetase, putative [Toxop...
646
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1TYC
18.7%
Toxoplasma gondii
IDP92119
(
show subtarget assignments
)
8
selected
No
TGME49_112520
237830353
tRNA delta(2)-isopentenylpyrophosphate t...
741
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3EPH
19.2%
Toxoplasma gondii
IDP92120
(
show subtarget assignments
)
8
selected
No
TGME49_073490
237833305
glutamine synthetase, putative [Toxoplas...
579
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3NG0
43.4%
Toxoplasma gondii
IDP92123
(
show subtarget assignments
)
8
selected
No
TGME49_110080
237829913
long-chain-fatty-acid-CoA ligase, putati...
841
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
Toxoplasma gondii
IDP92124
(
show subtarget assignments
)
8
selected
No
TGME49_110150
237829927
long-chain-fatty-acid-CoA ligase, putati...
866
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
Toxoplasma gondii
IDP92126
(
show subtarget assignments
)
8
selected
No
TGME49_068650
237832521
clp ATP-binding chain B1, putative [Toxo...
929
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1QVR
48.9%
Toxoplasma gondii
IDP92127
(
show subtarget assignments
)
8
selected
No
TGME49_021310
237841325
aminopeptidase N, putative [Toxoplasma g...
966
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
2GTQ
33.6%
Toxoplasma gondii
IDP92132
(
show subtarget assignments
)
8
selected
No
TGME49_053290
237840177
valyl-tRNA synthetase, putative [Toxopla...
1042
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1GAX
35.3%
Toxoplasma gondii
IDP92133
(
show subtarget assignments
)
8
selected
No
TGME49_033110
211965834
inosine-5'-monophosphate dehydrogenase, ...
551
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1JCN
53.6%
Toxoplasma gondii
IDP92135
(
show subtarget assignments
)
8
selected
No
TGME49_045670
211964661
pyruvate dehydrogenase, putative [Toxopl...
635
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
1NI4
20.6%
Toxoplasma gondii
IDP92136
(
show subtarget assignments
)
8
selected
No
TGME49_112510
211962137
hypothetical protein TGME49_112510 [Toxo...
1107
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
Toxoplasma gondii
IDP92554
(
show subtarget assignments
)
8
selected
No
VV1_1165
27360700
Glycerol-3-phosphate acyltransferase [Vi...
809
potential drug target /
Proteins are in a pathway we are investigating for playing a role in symbiont nu...
Community Requests
Vibrio vulnificus
IDP92553
(
show subtarget assignments
)
8
selected
No
VV1_2233
27361706
fadR
fatty acid metabolism transcriptional re...
279
potential drug target /
Proteins are in a pathway we are investigating for playing a role in symbiont nu...
Community Requests
1E2X
52%
Vibrio vulnificus
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