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Targets
Filter Targets:
Selection Phase:
No Filter
Community Interest
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM10+
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
[Clostridium] difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
0
1
6
8
Keyword:
Type Keyword
Stage:
No Filter
cloned
crystallized
crystal_structure
diffraction
expressed
in_crystallization_trials
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Screening
No Filter
Yes
No
Remove Filters
Download data as tab-separated value (TSV) file
(which can be used as a input for Microsoft Office Excel and Open Office Calc)
Jump to Target:
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IDP#
NCBI GI
LOCUS TAG
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Page 5 of 60, showing 100 records out of 5973 total, starting on record 401
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CSGID ID
Priority
stage
Screening
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP04606
(
show subtarget assignments
)
1
cloned
No
BAS3692
49186691
tRNA (guanine-N(1)-)-methyltransferase [...
244
Proposed to be essential proteins
Phase 4: April 2009
3KY7
62.3%
Bacillus anthracis
IDP04607
(
show subtarget assignments
)
1
cloned
No
BAS3700
49186699
ribonuclease III [Bacillus anthracis str...
245
Proposed to be essential proteins
Phase 4: April 2009
1O0W
40%
Bacillus anthracis
IDP04611
(
show subtarget assignments
)
1
cloned
No
BAS3754
49186753
sporulation sigma factor SigG [Bacillus ...
289
Proposed to be essential proteins
Phase 4: April 2009
1L0O
37%
Bacillus anthracis
IDP04609
(
show subtarget assignments
)
1
soluble
No
BAS3712
49186711
ribosome-associated GTPase [Bacillus ant...
293
Proposed to be essential proteins
Phase 4: April 2009
1T9H
63.4%
Bacillus anthracis
IDP04610
(
show subtarget assignments
)
1
in_pdb
3RFO
No
BAS3717
49186716
methionyl-tRNA formyltransferase [Bacill...
314
Proposed to be essential proteins
Phase 4: April 2009
3RFO
100%
Bacillus anthracis
IDP04624
(
show subtarget assignments
)
1
in_pdb
3B2B
3UWD
No
BAS4988
49187974
phosphoglycerate kinase [Bacillus anthra...
394
Proposed to be essential proteins
Phase 4: April 2009
3B2B
99.7%
Bacillus anthracis
IDP04613
(
show subtarget assignments
)
1
cloned
No
BAS3890
49186888
M20/M25/M40 family peptidase [Bacillus a...
376
Proposed to be essential proteins
Phase 4: April 2009
1YSJ
35.6%
Bacillus anthracis
IDP04614
(
show subtarget assignments
)
1
purified
No
BAS4131
49187128
glycine cleavage system aminomethyltrans...
366
Proposed to be essential proteins
Phase 4: April 2009
1YX2
66.1%
Bacillus anthracis
IDP04617
(
show subtarget assignments
)
1
expressed
No
BAS4342
49187337
50S ribosomal protein L21 [Bacillus anth...
102
Proposed to be essential proteins
Phase 4: April 2009
1VSA
54.9%
Bacillus anthracis
IDP04616
(
show subtarget assignments
)
1
in_crystallization_trials
No
BAS4313
49187308
S-adenosylmethionine:tRNA ribosyltransfe...
350
Proposed to be essential proteins
Phase 4: April 2009
1YY3
71.4%
Bacillus anthracis
IDP04622
(
show subtarget assignments
)
1
soluble
No
BAS4556
49187550
tyrosyl-tRNA synthetase [Bacillus anthra...
418
potential drug target /
Proposed to be essential proteins
Phase 4: April 2009
2TS1
70.6%
Bacillus anthracis
IDP04619
(
show subtarget assignments
)
1
in_pdb
4DIB
No
BAS4478
49187473
glyceraldehyde-3-phosphate dehydrogenase...
342
Proposed to be essential proteins
Phase 4: April 2009
4DIB
100%
Bacillus anthracis
IDP04621
(
show subtarget assignments
)
1
cloned
No
BAS4494
49187489
acetyl-CoA carboxylase carboxyltransfera...
324
Proposed to be essential proteins
Phase 4: April 2009
2F9I
60.2%
Bacillus anthracis
IDP04620
(
show subtarget assignments
)
1
cloned
No
BAS4482
49187477
DNA polymerase I [Bacillus anthracis str...
891
Proposed to be essential proteins
Phase 4: April 2009
3TAN
45%
Bacillus anthracis
IDP04627
(
show subtarget assignments
)
8
cloned
No
BAS5321
49188305
replicative DNA helicase [Bacillus anthr...
453
Proposed to be essential proteins
Community Requests
2VYE
75.3%
Bacillus anthracis
IDP04636
(
show subtarget assignments
)
1
soluble
No
FTT0238
56707395
aroE1
shikimate 5-dehydrogenase [Francisella t...
257
drug target; conserved gene;
Phase 4: April 2009
3O8Q
36.8%
Francisella tularensis
IDP04626
(
show subtarget assignments
)
1
cloned
No
BAS5178
49188164
peptide chain release factor 1 [Bacillus...
358
Proposed to be essential proteins
Phase 4: April 2009
1ZBT
59.2%
Bacillus anthracis
IDP90983
(
show subtarget assignments
)
8
selected
No
y0870
22124781
katG
catalase-peroxidase [Yersinia pestis KIM...
751
virulence/pathogenesis /
stress response protein and antigen in Y pestis
Community Requests
2FXG
59.4%
Yersinia pestis
IDP04633
(
show subtarget assignments
)
1
in_pdb
4EEI
No
FTT0015
56707195
purB
adenylosuccinate lyase [Francisella tula...
432
conserved gene; putative drug target function;
Phase 4: April 2009
4EEI
100%
Francisella tularensis
IDP04628
(
show subtarget assignments
)
1
soluble
No
BAS5322
49188306
50S ribosomal protein L9 [Bacillus anthr...
148
Proposed to be essential proteins
Phase 4: April 2009
1DIV
75%
Bacillus anthracis
IDP04634
(
show subtarget assignments
)
1
in_pdb
3MSU
No
FTT0071c
56707250
gltA
citrate synthase [Francisella tularensis...
424
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
3MSU
100%
Francisella tularensis
IDP04652
(
show subtarget assignments
)
1
in_crystallization_trials
No
FTT1432c
56708477
ppnK
inorganic phosphate/ATP-NAD kinase [Fran...
296
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
2AN1
41.6%
Francisella tularensis
IDP04642
(
show subtarget assignments
)
1
expressed
No
FTT0716
56707835
upp
uracil phosphoribosyltransferase [Franci...
214
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
2EHJ
69.2%
Francisella tularensis
IDP04651
(
show subtarget assignments
)
1
cloned
No
FTT1417
56708464
carbon-nitrogen hydrolase [Francisella t...
261
drug target; conserved gene;
Phase 4: April 2009
2E11
34.3%
Francisella tularensis
IDP04637
(
show subtarget assignments
)
1
cloned
No
FTT0371c
56707522
folC
FolC bifunctional protein [Francisella t...
393
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
1W78
29.8%
Francisella tularensis
IDP04638
(
show subtarget assignments
)
1
expressed
No
FTT0372c
56707523
accD
Acetyl-CoA carboxylase beta subunit [Fra...
302
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
2F9Y
60.3%
Francisella tularensis
IDP04650
(
show subtarget assignments
)
1
expressed
No
FTT1302
56708360
hypothetical protein FTT_1302 [Francisel...
276
drug target; conserved gene;
Phase 4: April 2009
3GBP
88.3%
Francisella tularensis
IDP91143
(
show subtarget assignments
)
8
in_pdb
3R2T
Yes
SAOUHSC_00393
88194188
superantigen-like protein [Staphylococcu...
232
potential drug target /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3R2T
100%
Staphylococcus aureus
IDP04647
(
show subtarget assignments
)
1
purified
No
FTT1127
56604696
Rhodanese-like family protein [Francisel...
252
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
1YT8
18.3%
Francisella tularensis
IDP04646
(
show subtarget assignments
)
1
soluble
No
FTT1085
56708168
hypothetical protein FTT_1085 [Francisel...
332
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
1QXN
9.3%
Francisella tularensis
IDP04730
(
show subtarget assignments
)
1
cloned
No
BAS4284
49187280
alanyl-tRNA synthetase [Bacillus anthrac...
880
Proposed to be essential proteins
Phase 4: April 2009
1RIQ
26.3%
Bacillus anthracis
IDP05672
(
show subtarget assignments
)
1
soluble
No
lmo0778
16802820
-
hypothetical protein lmo0778 [Listeria m...
115
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Listeria monocytogenes
IDP04707
(
show subtarget assignments
)
1
cloned
No
BAS0113
49183147
50S ribosomal protein L2 [Bacillus anthr...
276
Proposed to be essential proteins
Phase 4: April 2009
1VSA
65%
Bacillus anthracis
IDP04654
(
show subtarget assignments
)
1
purified
No
FTT1526c
56708560
idh
isocitrate dehydrogenase [Francisella tu...
747
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
1ITW
62.7%
Francisella tularensis
IDP04706
(
show subtarget assignments
)
1
expressed
No
BAS0105
49183139
30S ribosomal protein S12 [Bacillus anth...
140
Proposed to be essential proteins
Phase 4: April 2009
2F4V
71.4%
Bacillus anthracis
IDP04658
(
show subtarget assignments
)
1
purified
No
FTT1736c
56708739
kdpD
two component sensor protein kdpD [Franc...
893
conserved gene;
Phase 4: April 2009
2R8R
11.4%
Francisella tularensis
IDP05667
(
show subtarget assignments
)
1
expressed
No
lmo0462
16802506
-
hypothetical protein lmo0462 [Listeria m...
161
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Listeria monocytogenes
IDP04663
(
show subtarget assignments
)
1
cloned
No
BAS5325
49188309
30S ribosomal protein S18 [Bacillus anth...
77
Proposed to be essential proteins
Phase 4: April 2009
1P6G
50.6%
Bacillus anthracis
IDP05675
(
show subtarget assignments
)
1
purified
No
lmo0953
16802993
-
hypothetical protein lmo0953 [Listeria m...
75
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Listeria monocytogenes
IDP05774
(
show subtarget assignments
)
1
in_pdb
3OSU
No
SAV1231
15924221
fabG
3-oxoacyl-(acyl-carrier protein) reducta...
246
potential drug target /
Potential drug target
Phase 5: 2010
3OSU
100%
Staphylococcus aureus
IDP04708
(
show subtarget assignments
)
1
purified
No
BAS0114
49183148
30S ribosomal protein S19 [Bacillus anth...
92
Proposed to be essential proteins
Phase 4: April 2009
1FJG
66.3%
Bacillus anthracis
IDP05677
(
show subtarget assignments
)
1
in_pdb
4EAE
No
lmo1068
16803108
-
hypothetical protein lmo1068 [Listeria m...
286
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
4EAE
65.4%
Listeria monocytogenes
IDP04728
(
show subtarget assignments
)
1
selected
No
BAS0102
49183136
DNA-directed RNA polymerase subunit beta...
1177
Proposed to be essential proteins
Phase 4: April 2009
1HQM
49.2%
Bacillus anthracis
IDP90980
(
show subtarget assignments
)
8
cloned
No
y0801
22124714
iron-sulfur cluster insertion protein Er...
119
other biological interest /
protein possibly involved in iron-sulfur cluster synthesis
Community Requests
2APN
75.6%
Yersinia pestis
IDP90979
(
show subtarget assignments
)
8
cloned
No
y0636
22124550
hypothetical protein y0636 [Yersinia pes...
158
other biological interest /
Found by experiment to have a DNA binding function - an unknown DNA binding prot...
Community Requests
2Y75
24.1%
Yersinia pestis
IDP05689
(
show subtarget assignments
)
1
cloned
No
lmo1654
16803694
-
putative cellsurface protein [Listeria m...
164
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Listeria monocytogenes
IDP05003
(
show subtarget assignments
)
1
cloned
No
BA_3309
30257855
hypothetical protein BA_3309 [Bacillus a...
31
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05373
(
show subtarget assignments
)
1
cloned
No
BA_3146
30257723
hypothetical protein BA_3146 [Bacillus a...
47
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05002
(
show subtarget assignments
)
1
cloned
No
lmo0086
16802134
-
hypothetical protein lmo0086 [Listeria m...
1959
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3TUF
2.8%
Listeria monocytogenes
IDP90255
(
show subtarget assignments
)
8
purified
No
SAR1777
49483940
pfkA
6-phosphofructokinase [Staphylococcus au...
322
(From requester) Identified as potential drug target for S. aureus MRSA. Am curr...
Community Requests
3U39
59.3%
Staphylococcus aureus
IDP05272
(
show subtarget assignments
)
1
in_crystallization_trials
No
lmo1649
16803689
-
hypothetical protein lmo1649 [Listeria m...
171
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Listeria monocytogenes
IDP05011
(
show subtarget assignments
)
1
soluble
No
BA_4970
30259463
hypothetical protein BA_4970 [Bacillus a...
139
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05018
(
show subtarget assignments
)
1
purified
No
BA_2679
30257293
hypothetical protein BA_2679 [Bacillus a...
47
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP91187
(
show subtarget assignments
)
1
in_pdb
3UZR
4DCA
Yes
AF207840_1
10130002
aph(2')-Ib
aminoglycoside phosphotransferase [Enter...
299
drug resistance /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3HAM
100%
Enterococcus faecium
IDP05273
(
show subtarget assignments
)
1
soluble
No
lmo1752
16803792
-
hypothetical protein lmo1752 [Listeria m...
251
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Listeria monocytogenes
IDP05278
(
show subtarget assignments
)
1
cloned
No
BA_5456
30259924
hypothetical protein BA_5456 [Bacillus a...
49
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05041
(
show subtarget assignments
)
1
purified
No
BA_2335
30256973
hypothetical protein BA_2335 [Bacillus a...
64
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05721
(
show subtarget assignments
)
1
expressed
No
BA_2686
30257298
hypothetical protein BA_2686 [Bacillus a...
312
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05033
(
show subtarget assignments
)
1
cloned
No
BA_1260
30255209
hypothetical protein BA_1260 [Bacillus a...
34
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05032
(
show subtarget assignments
)
1
cloned
No
BA_1198
30255151
hypothetical protein BA_1198 [Bacillus a...
47
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05036
(
show subtarget assignments
)
1
cloned
No
BA_1663
30255960
hypothetical protein BA_1663 [Bacillus a...
450
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP91191
(
show subtarget assignments
)
1
in_pdb
4EJ7
3R78
No
CAJ77079
90265397
aphA1
Aminoglycoside phosphotransferase [Acine...
271
drug resistance /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3R78
100%
Acinetobacter baumannii
IDP05046
(
show subtarget assignments
)
1
expressed
No
BA_3529
30258064
hypothetical protein BA_3529 [Bacillus a...
117
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05720
(
show subtarget assignments
)
1
expressed
No
BA_2461
30257091
hypothetical protein BA_2461 [Bacillus a...
48
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP90228
(
show subtarget assignments
)
1
in_pdb
3T5P
3S40
No
BAS4713
49187704
-
Transcription regulator [contains diacyl...
300
Transcription regulator [contains diacylglycerol kinase catalytic domain]; Predi...
January 2009
3S40
100%
Bacillus anthracis
IDP91195
(
show subtarget assignments
)
8
cloned
No
BAS4091
49187089
-
Stage III sporulation protein AG
220
essential/virulence/pathogenesis /
Essential proteins
Community Requests
Bacillus anthracis
IDP05365
(
show subtarget assignments
)
1
expressed
No
BA_2909
30257501
hypothetical protein BA_2909 [Bacillus a...
56
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05375
(
show subtarget assignments
)
1
expressed
No
BA_4118
30258624
hypothetical protein BA_4118 [Bacillus a...
57
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05094
(
show subtarget assignments
)
1
purified
No
BA_3160
30257733
hypothetical protein BA_3160 [Bacillus a...
257
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05087
(
show subtarget assignments
)
1
cloned
No
BA_0335
30253873
hypothetical protein BA_0335 [Bacillus a...
184
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05378
(
show subtarget assignments
)
1
soluble
No
BA_4133
30258639
hypothetical protein BA_4133 [Bacillus a...
81
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05388
(
show subtarget assignments
)
1
soluble
No
BA_2383
30257018
hypothetical protein BA_2383 [Bacillus a...
191
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP91302
(
show subtarget assignments
)
8
soluble
No
STM2378
16765705
fabB
3-oxoacyl-(acyl carrier protein) synthas...
404
potential drug target /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
1FJ4
96.8%
Salmonella enterica
IDP05317
(
show subtarget assignments
)
1
cloned
No
lmo0638
16802680
-
hypothetical protein lmo0638 [Listeria m...
209
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Listeria monocytogenes
IDP05389
(
show subtarget assignments
)
1
cloned
No
BA_2660
30257276
hypothetical protein BA_2660 [Bacillus a...
31
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05386
(
show subtarget assignments
)
1
soluble
No
BA_2029
30256682
hypothetical protein BA_2029 [Bacillus a...
168
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05383
(
show subtarget assignments
)
1
purified
No
BA_1433
30255366
hypothetical protein BA_1433 [Bacillus a...
55
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP91305
(
show subtarget assignments
)
8
soluble
No
STM3477
16766765
cysG
siroheme synthase
457
potential drug target /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
1PJQ
99.8%
Salmonella enterica
IDP05374
(
show subtarget assignments
)
1
cloned
No
BA_3570
30258098
hypothetical protein BA_3570 [Bacillus a...
63
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05725
(
show subtarget assignments
)
1
soluble
No
BA_3844
30258362
hypothetical protein BA_3844 [Bacillus a...
81
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP90977
(
show subtarget assignments
)
8
soluble
No
y0320
22124237
oxyR
DNA-binding transcriptional regulator Ox...
305
other biological interest /
important global regulator
Community Requests
1I6A
59.7%
Yersinia pestis
IDP05162
(
show subtarget assignments
)
1
soluble
No
BA_1701
30255991
hypothetical protein BA_1701 [Bacillus a...
225
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05416
(
show subtarget assignments
)
1
purified
No
BA_4778
30259264
hypothetical protein BA_4778 [Bacillus a...
57
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05363
(
show subtarget assignments
)
1
soluble
No
BA_2032
30256684
hypothetical protein BA_2032 [Bacillus a...
148
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05175
(
show subtarget assignments
)
1
expressed
No
lmo1656
16803696
-
hypothetical protein lmo1656 [Listeria m...
143
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Listeria monocytogenes
IDP05400
(
show subtarget assignments
)
1
cloned
No
BA_0243
30253741
hypothetical protein BA_0243 [Bacillus a...
36
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP90257
(
show subtarget assignments
)
8
purified
No
SAR1996
49484145
lig
DNA ligase [Staphylococcus aureus subsp....
667
(From requester) potential drug target for S. aureus
Community Requests
3JSL
46.3%
Staphylococcus aureus
IDP05757
(
show subtarget assignments
)
1
cloned
No
lmo0881
16802922
-
hypothetical protein lmo0881 [Listeria m...
159
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Listeria monocytogenes
IDP91205
(
show subtarget assignments
)
8
soluble
No
BT_3975
29349383
3-dehydroquinate synthase [Bacteroides t...
353
potential drug target /
Shikimate pathway enzyme
Community Requests
3CLH
34.3%
Bacteroides thetaiotaomicron
IDP05396
(
show subtarget assignments
)
1
cloned
No
BA_3329
30257874
hypothetical protein BA_3329 [Bacillus a...
41
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05763
(
show subtarget assignments
)
1
cloned
No
lmo2331
16804370
-
hypothetical protein lmo2331 [Listeria m...
226
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Listeria monocytogenes
IDP05393
(
show subtarget assignments
)
1
expressed
No
BA_3225
30257788
hypothetical protein BA_3225 [Bacillus a...
200
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP91207
(
show subtarget assignments
)
8
soluble
No
BT_2842
29348251
3-dehydroquinate dehydratase [Bacteroide...
140
potential drug target /
Shikimate pathway enzyme
Community Requests
2C4W
49%
Bacteroides thetaiotaomicron
IDP05753
(
show subtarget assignments
)
1
cloned
No
lmo0461
16802505
-
hypothetical protein lmo0461 [Listeria m...
157
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Listeria monocytogenes
IDP05410
(
show subtarget assignments
)
1
soluble
No
BA_2500
30257128
hypothetical protein BA_2500 [Bacillus a...
156
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP05413
(
show subtarget assignments
)
1
cloned
No
BA_3890
30258404
hypothetical protein BA_3890 [Bacillus a...
30
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP90976
(
show subtarget assignments
)
8
cloned
No
y0137
22124057
degQ
protease [Yersinia pestis KIM 10]
463
other biological interest /
bifunctional chaperone / protease
Community Requests
4A8A
67.6%
Yersinia pestis
IDP05221
(
show subtarget assignments
)
1
expressed
No
BA_4349
30258849
hypothetical protein BA_4349 [Bacillus a...
62
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
IDP91325
(
show subtarget assignments
)
8
cloned
No
VV2_0292
27366738
hypothetical protein VV2_0292 [Vibrio vu...
229
essential/virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
Vibrio vulnificus
IDP91324
(
show subtarget assignments
)
8
cloned
No
VV2_0293
27366739
methyl-accepting chemotaxis protein [Vib...
156
essential/virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
Vibrio vulnificus
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