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Targets
Filter Targets:
Selection Phase:
No Filter
Community Interest
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM10+
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
[Clostridium] difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
0
1
6
8
Keyword:
Type Keyword
Stage:
No Filter
cloned
crystallized
crystal_structure
diffraction
expressed
in_crystallization_trials
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Screening
No Filter
Yes
No
Remove Filters
Download data as tab-separated value (TSV) file
(which can be used as a input for Microsoft Office Excel and Open Office Calc)
Jump to Target:
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IDP#
NCBI GI
LOCUS TAG
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Page 6 of 60, showing 100 records out of 5973 total, starting on record 501
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CSGID ID
Priority
stage
Screening
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP90404
(
show subtarget assignments
)
8
cloned
No
CT_654
3329104
hypothetical protein [Chlamydia trachoma...
162
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90277
(
show subtarget assignments
)
8
soluble
No
TGME49_059690
211962827
orotidine-monophosphate-decarboxylase, p...
320
The orotidine monophosphate decarboxylase (TgODCase) is the last step in de novo...
Community Requests
3QW3
39.1%
Toxoplasma gondii
IDP01530
(
show subtarget assignments
)
1
in_pdb
3EFV
3ETF
No
STM1524
16764869
yneI
putative succinate-semialdehyde dehydrog...
462
It is an essential gene in Salmonella which is important in energy metabolism.
Phase 3: June 2008
3EFV
100%
Salmonella enterica
IDP90280
(
show subtarget assignments
)
8
selected
No
TGME49_004420
211965378
oocyst wall protein COWP, putative [Toxo...
499
Unpublished data from a differentiation mutagenesis screen indicate that the ooc...
Community Requests
1N7D
19%
Toxoplasma gondii
IDP01109
(
show subtarget assignments
)
1
soluble
No
GBAA_pXO1_0148
47566460
hypothetical protein GBAA_pXO1_0148
150
Virulence Associated Factor
Phase 2: March 2008
3PMD
100%
Bacillus anthracis
IDP90345
(
show subtarget assignments
)
8
cloned
No
CT157
15604876
phospholipase D endonuclease superfamily...
404
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
1BYR
8.9%
Chlamydia trachomatis
IDP90283
(
show subtarget assignments
)
8
cloned
No
TGME49_075440
211969603
GRA6
granule antigen protein GRA6 [Toxoplasma...
224
GRA6 is a secreted dense granule protein that generates protective immunity, e.g...
Community Requests
Toxoplasma gondii
IDP90342
(
show subtarget assignments
)
8
expressed
No
CT155
15604874
phospholipase D endonuclease superfamily...
313
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP01531
(
show subtarget assignments
)
1
in_pdb
3EFB
No
SF4094
56384059
sorC
probable sor-operon regulator [Shigella ...
315
These targets are similar to actual drug targets and will be used mostly for coc...
Phase 3: June 2008
2W48
86.3%
Shigella flexneri
IDP01540
(
show subtarget assignments
)
1
in_pdb
3EC6
No
GBAA0418
47525694
general stress protein 26 [Bacillus anth...
138
CONSERVED
Phase 3: June 2008
3EC6
100%
Bacillus anthracis
IDP00002
(
show subtarget assignments
)
1
expressed
No
GBAA_pXO1_0079
47566400
-
surface layer protein, (pxo1-54)
404
Drug Target Homolog
Phase 1: October 2007
3PYW
14.4%
Bacillus anthracis
IDP90087
(
show subtarget assignments
)
8
cloned
No
ZZZ_0003
168
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90099
(
show subtarget assignments
)
8
cloned
No
ZZZ_0015
1137
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90536
(
show subtarget assignments
)
8
in_crystallization_trials
No
Cj0187c
15791574
purN
phosphoribosylglycinamide formyltransfer...
188
Predicted Essential
Community Requests
1C2T
38.6%
Campylobacter jejuni
IDP90086
(
show subtarget assignments
)
8
expressed
No
ZZZ_0002
492
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90571
(
show subtarget assignments
)
8
expressed
No
YPO0416
16120749
putative lipopolysaccharide core biosynt...
346
Predicted Essential
Community Requests
3TOV
24.9%
Yersinia pestis
IDP90085
(
show subtarget assignments
)
8
purified
No
ZZZ_0001
158
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90084
(
show subtarget assignments
)
8
soluble
No
ZP_01795673
145640079
hypothetical protein CGSHiII_00674 [Haem...
148
The protein we would like structure analyzed is from Haemophilus influenzae. Pri...
Community Requests
2XM6
28.4%
Haemophilus influenzae
IDP90311
(
show subtarget assignments
)
8
cloned
No
CT_734
3329192
hypothetical protein [Chlamydia trachoma...
221
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90088
(
show subtarget assignments
)
8
soluble
No
ZZZ_0004
140
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90367
(
show subtarget assignments
)
8
expressed
No
CT_144
3328544
hypothetical protein [Chlamydia trachoma...
285
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90091
(
show subtarget assignments
)
8
expressed
No
ZZZ_0007
660
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
2P5Z
15.6%
Escherichia coli
IDP00300
(
show subtarget assignments
)
1
cloned
No
CBU_1153
548
These targets are similar to actual drug targets and will be used mostly for coc...
Phase 2: March 2008
1GXB
10.4%
Coxiella burnetii
IDP01166
(
show subtarget assignments
)
1
cloned
No
GBAA_pXO1_0190
47566502
hypothetical protein GBAA_pXO1_0190
410
Virulence Associated Factor
Phase 2: March 2008
Bacillus anthracis
IDP00301
(
show subtarget assignments
)
1
expressed
No
CBU_0983
291
These targets are similar to actual drug targets and will be used mostly for coc...
Phase 2: March 2008
3NVT
10.7%
Coxiella burnetii
IDP90089
(
show subtarget assignments
)
8
expressed
No
ZZZ_0005
600
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90095
(
show subtarget assignments
)
8
soluble
No
ZZZ_0011
184
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90411
(
show subtarget assignments
)
8
expressed
No
CT_647
3329096
hypothetical protein [Chlamydia trachoma...
192
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90119
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_029
68449103
ankyrin-like protein [Monkeypox virus]
442
similar to VACV-COP-M1L, MPXV-ZAI96-O1L
Community Requests
1N11
16.3%
Monkeypox virus
IDP90092
(
show subtarget assignments
)
8
purified
No
ZZZ_0008
155
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90098
(
show subtarget assignments
)
8
purified
No
ZZZ_0014
196
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
3U66
19.4%
Escherichia coli
IDP90094
(
show subtarget assignments
)
8
cloned
No
ZZZ_0010
358
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90093
(
show subtarget assignments
)
8
expressed
No
ZZZ_0009
99
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP01169
(
show subtarget assignments
)
1
cloned
No
GBAA_pXO1_0146
47566458
atxA
transcriptional activator atxa, (pxo1-11...
475
Virulence Associated Factor
Phase 2: March 2008
3SQN
20.4%
Bacillus anthracis
IDP90420
(
show subtarget assignments
)
8
cloned
No
CT_465
3328899
hypothetical protein [Chlamydia trachoma...
213
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90097
(
show subtarget assignments
)
8
cloned
No
ZZZ_0013
104
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90408
(
show subtarget assignments
)
8
expressed
No
CT_631
3329079
hypothetical protein [Chlamydia trachoma...
84
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90141
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_186
68449257
ser/thr protein kinase-like protein [Mon...
282
similar to VACV-COP-B12R, MPXV-ZAI96-B11R
Community Requests
2KTY
32.4%
Monkeypox virus
IDP90096
(
show subtarget assignments
)
8
expressed
No
ZZZ_0012
476
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90585
(
show subtarget assignments
)
8
purified
No
Cj0949c
15792278
peptidyl-arginine deiminase family prote...
325
Predicted Essential
Community Requests
3HVM
45.8%
Campylobacter jejuni
IDP90587
(
show subtarget assignments
)
8
in_pdb
3LXM
Yes
YPO3588
16123730
pyrB
aspartate carbamoyltransferase catalytic...
311
Predicted Essential
Community Requests
3LXM
100%
Yersinia pestis
IDP90588
(
show subtarget assignments
)
8
cloned
No
Q9KLX5
23821639
RecName: Full=GTP cyclohydrolase 1; AltN...
217
Predicted Essential
Community Requests
1FBX
70.5%
Vibrio cholerae
IDP90292
(
show subtarget assignments
)
8
cloned
No
TGGT1_004130
221483205
histone acetyltransferase GCN5, putative...
1169
The histone acetyltransferase TgGCN-5A acetylates prerentially Histone 3 [K18], ...
Community Requests
1Z4R
8.5%
Toxoplasma gondii
IDP90106
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_011
68449085
secreted epidermal growth factor-like pr...
142
similar to VACV-COP-C11R, MPXV-ZAI96-D3R
Community Requests
1K36
16.2%
Monkeypox virus
IDP90101
(
show subtarget assignments
)
8
in_crystallization_trials
No
STM2287
16765614
sseL
deubiquitinase [Salmonella typhimurium L...
317
SseL, is a ubiquitin isopeptidase that plays a critical role in the virulence an...
Community Requests
Salmonella enterica
IDP90289
(
show subtarget assignments
)
8
purified
No
TGME49_094270
211967870
arginine methyltransferase protein, puta...
660
Epigenetic is an emerging field in Toxoplasma biology that will provide new targ...
Community Requests
2Y1W
24.5%
Toxoplasma gondii
IDP90100
(
show subtarget assignments
)
8
expressed
No
ZZZ_0016
849
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
1QVR
36.8%
Escherichia coli
IDP90415
(
show subtarget assignments
)
8
cloned
No
CT_443
3328874
omcB
60kDa Cysteine-Rich OMP [Chlamydia trach...
553
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90567
(
show subtarget assignments
)
8
in_pdb
3R2E
No
YPO0648
16120973
folB
bifunctional dihydroneopterin aldolase/d...
119
Predicted Essential
Community Requests
3R2E
100%
Yersinia pestis
IDP90118
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_028
68449102
alpha-amanitin target protein [Monkeypox...
177
similar to VACV-COP-N2L, MPXV-ZAI96-P2L
Community Requests
Monkeypox virus
IDP90105
(
show subtarget assignments
)
8
expressed
No
MPXV_ZAI1979_005_008
68449082
unknown [Monkeypox virus]
56
similar to part of CPXV-GRI-C3L
Community Requests
Monkeypox virus
IDP90102
(
show subtarget assignments
)
8
expressed
No
MPXV_ZAI1979_005_002
68449079
TNF-alpha-receptor-like protein [Monkeyp...
348
similar to VACV-COP-C22L/B28R, MPXV-ZAI96-J2L/J2R
Community Requests
3ON9
23.6%
Monkeypox virus
IDP90362
(
show subtarget assignments
)
8
soluble
No
CT_053
3328445
hypothetical protein [Chlamydia trachoma...
148
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90348
(
show subtarget assignments
)
8
expressed
No
CT166
15604885
hypothetical protein CT166 [Chlamydia tr...
639
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3SRZ
15.6%
Chlamydia trachomatis
IDP90104
(
show subtarget assignments
)
8
expressed
No
MPXV_ZAI1979_005_004
68449081
ankyrin-like protein [Monkeypox virus]
437
similar to CPXV-GRI-C1L, MPXV-ZAI96-D1L/N4R
Community Requests
2Y1L
9.6%
Monkeypox virus
IDP90295
(
show subtarget assignments
)
8
cloned
No
TGME49_005290
211965425
dual-specificity phosphatase laforin, pu...
523
Human Lafora disease is one of five major progressive myoclonus epilepsies that ...
Community Requests
Toxoplasma gondii
IDP90291
(
show subtarget assignments
)
8
soluble
No
TGME49_081900
211969063
high mobility group (HMG) box domain-con...
880
The newly described histone lysine methyl-transferase KMTox targets histones H4 ...
Community Requests
Toxoplasma gondii
IDP90103
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_003
68449080
ankyrin-like protein [Monkeypox virus]
587
similar to VACV-COP-B25R/C19L, MPXV-ZAI96-J3L/J1R
Community Requests
Monkeypox virus
IDP90117
(
show subtarget assignments
)
8
in_crystallization_trials
No
MPXV_ZAI1979_005_027
68449101
virokine protein [Monkeypox virus]
117
similar to VACV-COP-N1L, MPXV-ZAI96-P1L
Community Requests
2I39
89.7%
Monkeypox virus
IDP90365
(
show subtarget assignments
)
8
cloned
No
CT_102
3328499
hypothetical protein [Chlamydia trachoma...
153
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90110
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_015
68449089
ankyrin-like protein [Monkeypox virus]
660
similar to CPXV-GRI-C9L,CPXV-BR-V024, MPXV-ZAI96-D7L
Community Requests
1N0Q
4.4%
Monkeypox virus
IDP90363
(
show subtarget assignments
)
8
cloned
No
CT_066
3328460
hypothetical protein [Chlamydia trachoma...
158
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90109
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_014
68449088
interleukin-18-binding protein [Monkeypo...
126
similar to VACWR-C12L,VARV-BSH75_banu-D7L, MPXV-ZAI96-D6L
Community Requests
3F62
79.4%
Monkeypox virus
IDP90107
(
show subtarget assignments
)
8
expressed
No
MPXV_ZAI1979_005_012
68449086
interleukin-1 receptor antagonist-like p...
83
similar to VACV-COP-C10L, MPXV-ZAI96-D4L
Community Requests
Monkeypox virus
IDP90108
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_013
68449087
bifunctional zinc finger-like protein/E3...
242
similar to VARV BEN68-zinc finger-like protein
Community Requests
2ECW
8.3%
Monkeypox virus
IDP90595
(
show subtarget assignments
)
8
expressed
No
YPO2298
16122522
phoA
alkaline phosphatase [Yersinia pestis CO...
481
Predicted Essential
Community Requests
1B8J
70.7%
Yersinia pestis
IDP90293
(
show subtarget assignments
)
8
in_pdb
3OTR
No
TGME49_068860
211963243
enolase 1 [Toxoplasma gondii ME49]
444
Complimentarily to TgENO1, enolase 2 (TgENO2) is expressed specifically in tachy...
Community Requests
3OTR
100%
Toxoplasma gondii
IDP90364
(
show subtarget assignments
)
8
expressed
No
CT_083
3328478
hypothetical protein [Chlamydia trachoma...
160
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90116
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_025
68449099
kelch-like protein [Monkeypox virus]
107
similar to MPXV-ZAI96-D18L, part of VACV-COP-C2L
Community Requests
3HVE
21.5%
Monkeypox virus
IDP90111
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_017
68449091
ankyrin-like protein [Monkeypox virus]
630
similar to VACV-COP-C9L, MPXV-ZAI96-D9L
Community Requests
3NOC
5.1%
Monkeypox virus
IDP90113
(
show subtarget assignments
)
8
expressed
No
MPXV_ZAI1979_005_021
68449095
unknown [Monkeypox virus]
315
similar to VACV-COP-C4L, MPXV-ZAI96-D13L
Community Requests
Monkeypox virus
IDP90112
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_019
68449093
unknown [Monkeypox virus]
153
similar to VACV-COP-C6L, MPXV-ZAI96-D11L
Community Requests
Monkeypox virus
IDP90114
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_023
68449097
kelch-like protein [Monkeypox virus]
105
similar to MPXV-ZAI96-D18L, part of VACV-COP-C2L
Community Requests
Monkeypox virus
IDP90115
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_024
68449098
kelch-like protein [Monkeypox virus]
176
similar to MPXV-ZAI96-D18L, part of VACV-COP-C2L
Community Requests
2XN4
26.1%
Monkeypox virus
IDP90120
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_030
68449104
unknown [Monkeypox virus]
220
similar to VACV-COP-M2L, MPXV-ZAI96-O2L
Community Requests
Monkeypox virus
IDP90298
(
show subtarget assignments
)
8
selected
No
TGME49_120190
211967550
bradyzoite-specific surface protein, put...
398
TgSRS9 is one of the few in the SAG1 family that is expressed only in bradyzoite...
Community Requests
2JKS
37.7%
Toxoplasma gondii
IDP90140
(
show subtarget assignments
)
8
expressed
No
MPXV_ZAI1979_005_184
68449255
6kDa intracellular viral protein [Monkey...
221
similar to VACV-COP-B9R, MPXV-ZAI96-B10R
Community Requests
Monkeypox virus
IDP90368
(
show subtarget assignments
)
8
expressed
No
CT_143
3328543
hypothetical protein [Chlamydia trachoma...
280
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90126
(
show subtarget assignments
)
8
expressed
No
MPXV_ZAI1979_005_044
68449118
unknown [Monkeypox virus]
212
thiol substrate, similar to VACV-COP-F9L, MPXV-ZAI96-C15L
Community Requests
1YPY
21.7%
Monkeypox virus
IDP90132
(
show subtarget assignments
)
8
expressed
No
MPXV_ZAI1979_005_155
68449229
unknown [Monkeypox virus]
176
similar to VACV-COP-A35R, MPXV-ZAI96-A37R
Community Requests
Monkeypox virus
IDP90373
(
show subtarget assignments
)
8
expressed
No
CT_191
3328596
hypothetical protein [Chlamydia trachoma...
116
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90347
(
show subtarget assignments
)
8
soluble
No
CT205
15604925
pfkA_1
diphosphate--fructose-6-phosphate 1-phos...
553
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
1KZH
36.9%
Chlamydia trachomatis
IDP90122
(
show subtarget assignments
)
8
expressed
No
MPXV_ZAI1979_005_032
68449106
serine protease inhibitor-likeprotein SP...
375
similar to VACV-COP-K2L, MPXV-ZAI96-C2L
Community Requests
3LW2
29.2%
Monkeypox virus
IDP90297
(
show subtarget assignments
)
8
purified
No
TGME49_065450
211966338
hexokinase [Toxoplasma gondii ME49]
468
Hexokinase (TgHK) is one of 5 major glycolytic enzymes characterized in Toxoplas...
Community Requests
1CZA
34.7%
Toxoplasma gondii
IDP90121
(
show subtarget assignments
)
8
purified
No
MPXV_ZAI1979_005_031
68449105
ankyrin-like protein [Monkeypox virus]
284
similar to VACV-COP-K1L, MPXV-ZAI96-C1L
Community Requests
3KEA
94.7%
Monkeypox virus
IDP90371
(
show subtarget assignments
)
8
cloned
No
CT_109
3328506
CHLPS hypothetical protein [Chlamydia tr...
262
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90125
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_038
68449112
kelch-like protein [Monkeypox virus]
485
similar to VACV-COP-F3L, MPXV-ZAI96-C9L
Community Requests
1ZGK
13.6%
Monkeypox virus
IDP90124
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_036
68449110
unknown [Monkeypox virus]
219
mitochondrial-associated inhibitor of apoptosis, similar to VACV-COP-F1L, MPXV-Z...
Community Requests
2VTY
69.4%
Monkeypox virus
IDP90123
(
show subtarget assignments
)
8
in_crystallization_trials
No
MPXV_ZAI1979_005_035
68449109
B15R-like protein [Monkeypox virus]
149
similar to VACV-COP-K7R, MPXV-ZAI96-C6R
Community Requests
2K36
94%
Monkeypox virus
IDP90369
(
show subtarget assignments
)
8
cloned
No
CT_181
3328585
hypothetical protein [Chlamydia trachoma...
236
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90301
(
show subtarget assignments
)
8
selected
No
TGME49_025290
211963866
nucleoside-triphosphatase, putative [Tox...
642
The T. gondii nucleoside triphosphate hydrolases (NTPase) are ecto ATPases with ...
Community Requests
3AGR
38.6%
Toxoplasma gondii
IDP90129
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_084
68449158
myristylprotein [Monkeypox virus]
340
similar to VACV-COP-G9R, MPXV-ZAI96-G10R
Community Requests
Monkeypox virus
IDP90302
(
show subtarget assignments
)
0
work_stopped
No
BB_0420
2688313
sensory transduction histidine kinase, p...
1494
Mutational studies suggest that Hk1 is required for the survival of the Lyme dis...
Community Requests
3A0R
5.6%
Borrelia burgdorferi
IDP01168
(
show subtarget assignments
)
1
expressed
No
GBAA_pXO2_0084
47566748
capsule synthesis trans-acting positive ...
483
Virulence Associated Factor
Phase 2: March 2008
3SQN
8.5%
Bacillus anthracis
IDP90127
(
show subtarget assignments
)
8
expressed
No
MPXV_ZAI1979_005_045
68449119
ser/thr kinase [Monkeypox virus]
439
similar to VACV-COP-F10L, MPXV-ZAI96-C16L
Community Requests
Monkeypox virus
IDP90423
(
show subtarget assignments
)
8
cloned
No
CT_444
3328876
omcA
9kDa-Cysteine-Rich Lipoprotein [Chlamydi...
88
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90128
(
show subtarget assignments
)
8
purified
No
MPXV_ZAI1979_005_060
68449134
myristylprotein [Monkeypox virus]
166
has N-myristyltransferase target MGxxxS/T/A, similar to VACV-COP-E7R, MPXV-ZAI96...
Community Requests
Monkeypox virus
IDP90131
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_144
68449218
cowpox A-type inclusion protein [Monkeyp...
67
similar to part of CPXV-GRI-A26L
Community Requests
Monkeypox virus
IDP90802
(
show subtarget assignments
)
8
in_crystallization_trials
No
YPO3769
16123905
3-octaprenyl-4-hydroxybenzoate decarboxy...
498
Predicted Essential
Community Requests
2IDB
88.2%
Yersinia pestis
IDP90801
(
show subtarget assignments
)
8
soluble
No
Cj1597
15792902
hisG
ATP phosphoribosyltransferase [Campyloba...
299
Predicted Essential
Community Requests
1H3D
66.2%
Campylobacter jejuni
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