|
|---|
| CSGID ID |
Priority |
stage |
Screening |
Locus Tag |
NCBI GI |
Gene
Name |
Common Name |
Sequence
Length |
Selection
Phase |
Homolog
PDB ID |
Homolog
Sequence
Identity |
Target Organism |
TIGR Main Role |
TIGR Subrole |
Request Person |
IDP00580
(show subtarget assignments)
|
1 |
purified |
No |
YPO0059 |
16120412 |
kbl |
2-amino-3-ketobutyrate coenzyme A ligase... |
403 |
Phase 2: March 2008 |
1FC4
|
82.9% |
Yersinia pestis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Biotin |
|
|
|
IDP00581
(show subtarget assignments)
|
1 |
in_pdb
3RDW |
Yes |
YPO3070 |
16123247 |
|
putative arsenate reductase |
118 |
Phase 2: March 2008 |
3RDW
|
100% |
Yersinia pestis |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00582
(show subtarget assignments)
|
1 |
in_pdb
3GSE |
Yes |
YPO2528 |
16122747 |
menF |
menaquinone-specific isochorismate synth... |
455 |
Phase 2: March 2008 |
3GSE
|
100% |
Yersinia pestis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Menaquinone and ubiquinone |
|
|
|
IDP00583
(show subtarget assignments)
|
1 |
expressed |
No |
YPO2752 |
16122956 |
mepA |
penicillin-insensitive murein endopeptid... |
275 |
Phase 2: March 2008 |
1TZP
|
67.6% |
Yersinia pestis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP00584
(show subtarget assignments)
|
1 |
soluble |
No |
YPO0117 |
16120462 |
metF |
5,10-methylenetetrahydrofolate reductase... |
294 |
Phase 2: March 2008 |
1ZP3
|
86.4% |
Yersinia pestis |
Amino acid biosynthesis |
Aspartate family |
|
|
|
IDP00585
(show subtarget assignments)
|
1 |
expressed |
No |
YPO0116 |
16120461 |
metL |
bifunctional aspartate kinase II/homoser... |
811 |
Phase 2: March 2008 |
1EBF
|
15.5% |
Yersinia pestis |
Amino acid biosynthesis |
Aspartate family |
|
|
|
IDP00586
(show subtarget assignments)
|
1 |
purified |
No |
YPO3789 |
16123923 |
metR |
lysR-family transcriptional regulatory p... |
317 |
Phase 2: March 2008 |
1AL3
|
23.7% |
Yersinia pestis |
Amino acid biosynthesis |
Aspartate family |
|
|
|
IDP00587
(show subtarget assignments)
|
1 |
cloned |
No |
YPO1507 |
16121780 |
mglB |
galactose-binding protein |
335 |
Phase 2: March 2008 |
1GCA
|
80.9% |
Yersinia pestis |
Transport and binding proteins |
Carbohydrates, organic alcohols, and acids |
|
|
|
IDP00588
(show subtarget assignments)
|
1 |
purified |
No |
YPO2077 |
16122316 |
minD |
cell division inhibitor MinD |
270 |
Phase 2: March 2008 |
3Q9L
|
87.8% |
Yersinia pestis |
Cellular processes |
Cell division |
|
|
|
IDP00589
(show subtarget assignments)
|
1 |
soluble |
No |
YPO0954 |
161486886 |
mltC |
membrane-bound lytic murein transglycosy... |
358 |
Phase 2: March 2008 |
2Y8P
|
19.3% |
Yersinia pestis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP00337
(show subtarget assignments)
|
1 |
expressed |
No |
FTT0946 |
56708043 |
trpG |
anthranilate synthase component II |
184 |
Phase 2: March 2008 |
1QDL
|
40.7% |
Francisella tularensis |
Amino acid biosynthesis |
Aromatic amino acid family |
|
|
|
IDP00679
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL1699 |
57284711 |
obgE |
GTPase ObgE |
430 |
Phase 2: March 2008 |
1LNZ
|
54.2% |
Staphylococcus aureus |
Unknown function |
General |
|
|
|
IDP00336
(show subtarget assignments)
|
1 |
cloned |
No |
FTT1186 |
56708252 |
smpB |
SsrA-binding protein |
157 |
Phase 2: March 2008 |
1P6V
|
48.4% |
Francisella tularensis |
Protein synthesis |
Other |
|
|
|
IDP00335
(show subtarget assignments)
|
1 |
in_pdb
3OUT |
No |
FTT1197c |
56708260 |
murI |
glutamate racemase |
265 |
Phase 2: March 2008 |
3OUT
|
100% |
Francisella tularensis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP00675
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL1455 |
57284564 |
|
carboxyl-terminal protease |
496 |
Phase 2: March 2008 |
1FC6
|
20% |
Staphylococcus aureus |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP00334
(show subtarget assignments)
|
1 |
in_pdb
3LYL |
No |
FTT1375 |
56708428 |
fabG |
3-oxoacyl-(acyl-carrier-protein) reducta... |
247 |
Phase 2: March 2008 |
3LYL
|
100% |
Francisella tularensis |
Fatty acid and phospholipid metabolism |
Biosynthesis |
|
|
|
IDP00151
(show subtarget assignments)
|
1 |
purified |
No |
VC0403 |
15640430 |
mshM |
MSHA biogenesis protein MshM |
281 |
Phase 1: October 2007 |
|
|
Vibrio cholerae |
Cellular processes |
Pathogenesis |
|
|
|
IDP00150
(show subtarget assignments)
|
1 |
purified |
No |
VC0402 |
15640429 |
mshL |
MSHA biogenesis protein MshL |
559 |
Phase 1: October 2007 |
|
|
Vibrio cholerae |
Cellular processes |
Pathogenesis |
|
|
|
IDP00333
(show subtarget assignments)
|
1 |
crystallized |
No |
FTT1487 |
56708526 |
coaE |
Dephospho-CoA kinase |
204 |
Phase 2: March 2008 |
1JJV
|
31.4% |
Francisella tularensis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Pantothenate and coenzyme A |
|
|
|
IDP00332
(show subtarget assignments)
|
1 |
purified |
No |
FTT1673 |
56708683 |
ribA |
riboflavin biosynthesis protein ribA/GTP... |
403 |
Phase 2: March 2008 |
1G57
|
27% |
Francisella tularensis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Riboflavin, FMN, and FAD |
|
|
|
IDP00149
(show subtarget assignments)
|
1 |
expressed |
No |
VCA0230 |
15600999 |
vctC |
vibriobactin and enterobactin ABC transp... |
254 |
Phase 1: October 2007 |
2D62
|
28% |
Vibrio cholerae |
Transport and binding proteins |
Cations and iron carrying compounds |
|
|
|
IDP00331
(show subtarget assignments)
|
1 |
in_pdb
3RE3 |
Yes |
FTT1128 |
56708205 |
ispF |
2C-methyl-D-erythritol 2,4-cyclodiphosph... |
159 |
Phase 2: March 2008 |
3RE3
|
100% |
Francisella tularensis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Other |
|
|
|
IDP00330
(show subtarget assignments)
|
1 |
purified |
No |
Cj0345 |
15791713 |
trpE |
putative anthranilate synthase component... |
416 |
Phase 2: March 2008 |
1QDL
|
32% |
Campylobacter jejuni |
Amino acid biosynthesis |
Aromatic amino acid family |
|
|
|
IDP00148
(show subtarget assignments)
|
1 |
soluble |
No |
VCA0227 |
15600996 |
vctP |
vibriobactin and enterobactin ABC transp... |
333 |
Phase 1: October 2007 |
3GFV
|
30.3% |
Vibrio cholerae |
Transport and binding proteins |
Cations and iron carrying compounds |
|
|
|
IDP00073
(show subtarget assignments)
|
1 |
crystallized |
No |
NT01ST3324 |
16421221 |
rimM |
16S rRNA processing protein |
182 |
Phase 1: October 2007 |
3H9N
|
63.2% |
Salmonella enterica |
Unclassified |
Role category not yet assigned |
|
|
|
IDP00329
(show subtarget assignments)
|
1 |
cloned |
No |
Cj1724c |
15793027 |
|
7-cyano-7-deazaguanine reductase |
127 |
Phase 2: March 2008 |
|
|
Campylobacter jejuni |
Amino acid biosynthesis |
Pyruvate family |
|
|
|
IDP00328
(show subtarget assignments)
|
1 |
in_pdb
3UHP
3UHF
3UHO |
No |
Cj1652c |
15792957 |
murI |
glutamate racemase |
250 |
Phase 2: March 2008 |
2JFX
|
53.7% |
Campylobacter jejuni |
Energy metabolism |
Pentose phosphate pathway |
|
|
|
IDP00147
(show subtarget assignments)
|
1 |
expressed |
No |
VC0780 |
15640799 |
vibD |
vibriobactin synthase component D |
261 |
Phase 1: October 2007 |
|
|
Vibrio cholerae |
Transport and binding proteins |
Cations and iron carrying compounds |
|
|
|
IDP00661
(show subtarget assignments)
|
1 |
purified |
No |
SACOL0827 |
57284289 |
|
acetyltransferase, putative |
161 |
Phase 2: March 2008 |
1OCX
|
30.4% |
Staphylococcus aureus |
Unknown function |
Enzymes of unknown specificity |
|
|
|
IDP00660
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL0816 |
57284278 |
secA |
preprotein translocase subunit SecA |
843 |
Phase 2: March 2008 |
1TF2
|
60.4% |
Staphylococcus aureus |
Protein fate |
Protein and peptide secretion and trafficking |
|
|
|
IDP00659
(show subtarget assignments)
|
1 |
soluble |
No |
SACOL0806 |
57285767 |
pepT |
peptidase T |
408 |
Phase 2: March 2008 |
3IFE
|
55.9% |
Staphylococcus aureus |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP00146
(show subtarget assignments)
|
1 |
soluble |
No |
VC0778 |
15640797 |
viuG |
vibriobactin and enterobactin ABC transp... |
358 |
Phase 1: October 2007 |
2QI9
|
28.2% |
Vibrio cholerae |
Transport and binding proteins |
Cations and iron carrying compounds |
|
|
|
IDP00072
(show subtarget assignments)
|
1 |
purified |
No |
NT01ST2585 |
16420605 |
hisB |
imidazole glycerol-phosphate dehydratase... |
355 |
Phase 1: October 2007 |
2FPR
|
43.1% |
Salmonella enterica |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00036
(show subtarget assignments)
|
1 |
purified |
No |
BA_1840 |
30256110 |
|
fibronectin-binding protein, putative |
213 |
Phase 1: October 2007 |
2YB5
|
32.9% |
Bacillus anthracis |
Cellular processes |
Pathogenesis |
|
|
|
IDP00009
(show subtarget assignments)
|
1 |
soluble |
No |
BA_1538 |
38372188 |
|
3-dehydroquinate synthase |
363 |
Phase 1: October 2007 |
1XAG
|
38.3% |
Bacillus anthracis |
Amino acid biosynthesis |
Aromatic amino acid family |
|
|
|
IDP00325
(show subtarget assignments)
|
1 |
crystallized |
No |
Cj1530 |
15792838 |
coaE |
dephospho-CoA kinase |
201 |
Phase 2: March 2008 |
2IF2
|
32.8% |
Campylobacter jejuni |
Unclassified |
Unclassified |
|
|
|
IDP00324
(show subtarget assignments)
|
1 |
cloned |
No |
Cj1366c |
15792689 |
glmS |
D-fructose-6-phosphate amidotransferase ... |
598 |
Phase 2: March 2008 |
1JXA
|
41.3% |
Campylobacter jejuni |
Unclassified |
Unclassified |
|
|
|
IDP00145
(show subtarget assignments)
|
1 |
expressed |
No |
VC0777 |
15640796 |
viuD |
vibriobactin and enterobactin ABC transp... |
350 |
Phase 1: October 2007 |
2NQ2
|
30.6% |
Vibrio cholerae |
Transport and binding proteins |
Cations and iron carrying compounds |
|
|
|
IDP00323
(show subtarget assignments)
|
1 |
crystallized |
No |
Cj0858c |
15792196 |
murA |
UDP-N-acetylglucosamine 1-carboxyvinyltr... |
418 |
Phase 2: March 2008 |
1NAW
|
49% |
Campylobacter jejuni |
Hypothetical proteins |
Conserved |
|
|
|
IDP00650
(show subtarget assignments)
|
1 |
soluble |
No |
SACOL0113 |
57286662 |
|
NAD-dependent epimerase/dehydratase fami... |
323 |
Phase 2: March 2008 |
1SB8
|
36.2% |
Staphylococcus aureus |
Cell envelope |
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
|
|
|
IDP00322
(show subtarget assignments)
|
1 |
expressed |
No |
Cj0346 |
15791714 |
trpD |
anthranilate synthase component II |
533 |
Phase 2: March 2008 |
1VQU
|
20.6% |
Campylobacter jejuni |
Amino acid biosynthesis |
Aromatic amino acid family |
|
|
|
IDP00144
(show subtarget assignments)
|
1 |
soluble |
No |
VC0776 |
15640795 |
viuP |
vibriobactin and enterobactin ABC transp... |
325 |
Phase 1: October 2007 |
3R5S
|
91.4% |
Vibrio cholerae |
Transport and binding proteins |
Cations and iron carrying compounds |
|
|
|
IDP00321
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
Cj1105 |
15792430 |
smpB |
SsrA-binding protein |
150 |
Phase 2: March 2008 |
1P6V
|
47.3% |
Campylobacter jejuni |
Purines, pyrimidines, nucleosides, and nucleotides |
Pyrimidine ribonucleotide biosynthesis |
|
|
|
IDP00320
(show subtarget assignments)
|
1 |
expressed |
No |
CBU_0550 |
29653890 |
pbpA |
penicillin-binding protein 2 |
612 |
Phase 2: March 2008 |
1MWR
|
25.3% |
Coxiella burnetii |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP00143
(show subtarget assignments)
|
1 |
soluble |
No |
VC0779 |
15640798 |
viuC |
vibriobactin and enterobactin ABC transp... |
279 |
Phase 1: October 2007 |
1B0U
|
29% |
Vibrio cholerae |
Transport and binding proteins |
Cations and iron carrying compounds |
|
|
|
IDP00319
(show subtarget assignments)
|
1 |
expressed |
No |
CBU_2070 |
29655348 |
|
chorismate mutase, putative |
136 |
Phase 2: March 2008 |
|
|
Coxiella burnetii |
Amino acid biosynthesis |
Aromatic amino acid family |
|
|
|
IDP00641
(show subtarget assignments)
|
1 |
purified |
No |
SACOL1866 |
57284787 |
|
serine protease SplD, putative |
239 |
Phase 2: March 2008 |
2VID
|
43.5% |
Staphylococcus aureus |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP00318
(show subtarget assignments)
|
1 |
cloned |
No |
CBU_1947 |
29655231 |
glmU |
UDP-N-acetylglucosamine pyrophosphorylas... |
455 |
Phase 2: March 2008 |
1HV9
|
51.4% |
Coxiella burnetii |
Cell envelope |
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
|
|
|
IDP00142
(show subtarget assignments)
|
1 |
cloned |
No |
VC1456 |
15641467 |
ctxB |
cholera enterotoxin, B subunit |
124 |
Phase 1: October 2007 |
1EEI
|
81.5% |
Vibrio cholerae |
Cellular processes |
Pathogenesis |
|
|
|
IDP00035
(show subtarget assignments)
|
1 |
soluble |
No |
BA_1589 |
30255889 |
|
macrolide 2-phosphotransferase, putative... |
298 |
Phase 1: October 2007 |
3LZH
|
17.8% |
Bacillus anthracis |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00640
(show subtarget assignments)
|
1 |
in_pdb
3EME
3MZZ |
No |
SACOL1807 |
57286241 |
|
rhodanese-like domain protein |
103 |
Phase 2: March 2008 |
3EME
|
100% |
Staphylococcus aureus |
Unknown function |
General |
|
|
|
IDP00639
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL0114 |
57286663 |
|
capsular polysaccharide biosynthesis gly... |
230 |
Phase 2: March 2008 |
|
|
Staphylococcus aureus |
Cell envelope |
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
|
|
|
IDP00317
(show subtarget assignments)
|
1 |
cloned |
No |
CBU_1887 |
29655172 |
ponA |
penicillin-binding protein 1A |
793 |
Phase 2: March 2008 |
3UDF
|
40.4% |
Coxiella burnetii |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP00638
(show subtarget assignments)
|
1 |
purified |
No |
SACOL2736 |
57285290 |
gidB |
glucose-inhibited division protein B |
239 |
Phase 2: March 2008 |
1XDZ
|
63.2% |
Staphylococcus aureus |
Unknown function |
General |
|
|
|
IDP00637
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL1727 |
57284738 |
infC |
translation initiation factor IF-3 |
175 |
Phase 2: March 2008 |
1TIG
|
37.7% |
Staphylococcus aureus |
Protein synthesis |
Translation factors |
|
|
|
IDP00316
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
CBU_1152 |
29654458 |
trpE |
anthranilate synthase component I |
463 |
Phase 2: March 2008 |
1QDL
|
34.3% |
Coxiella burnetii |
Amino acid biosynthesis |
Aromatic amino acid family |
|
|
|
IDP00141
(show subtarget assignments)
|
1 |
crystallized |
No |
VC0401 |
15640428 |
mshK |
MSHA biogenesis protein MshK |
105 |
Phase 1: October 2007 |
|
|
Vibrio cholerae |
Cellular processes |
Pathogenesis |
|
|
|
IDP00636
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL1118 |
57285904 |
typA |
GTP-binding protein TypA |
615 |
Phase 2: March 2008 |
3E3X
|
27.6% |
Staphylococcus aureus |
Unknown function |
General |
|
|
|
IDP00635
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL2270 |
57286396 |
modC |
molybdenum ABC transporter, ATP-binding ... |
201 |
Phase 2: March 2008 |
2IT1
|
38.8% |
Staphylococcus aureus |
Transport and binding proteins |
Anions |
|
|
|
IDP00642
(show subtarget assignments)
|
1 |
soluble |
No |
SACOL2384 |
57285116 |
sarZ |
staphylococcal accessory protein Z |
148 |
Phase 2: March 2008 |
3HRM
|
91.9% |
Staphylococcus aureus |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00643
(show subtarget assignments)
|
1 |
purified |
No |
SACOL2638 |
57286542 |
|
precorrin-2 dehydrogenase |
201 |
Phase 2: March 2008 |
3DFZ
|
33.8% |
Staphylococcus aureus |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Heme, porphyrin, and cobalamin |
|
|
|
IDP00644
(show subtarget assignments)
|
1 |
expressed |
No |
SACOL0220 |
57286684 |
|
flavohemoprotein, putative |
381 |
Phase 2: March 2008 |
1CQX
|
36.9% |
Staphylococcus aureus |
Unknown function |
General |
|
|
|
IDP00646
(show subtarget assignments)
|
1 |
selected |
No |
SACOL0887 |
57284346 |
sei |
staphylococcal enterotoxin type I |
242 |
Phase 2: March 2008 |
2G9H
|
55% |
Staphylococcus aureus |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00647
(show subtarget assignments)
|
1 |
selected |
No |
SACOL1657 |
57286179 |
|
enterotoxin type A, putative |
234 |
Phase 2: March 2008 |
1ESF
|
40.2% |
Staphylococcus aureus |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00648
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL2160 |
57286373 |
|
hemolysin III, putative |
227 |
Phase 2: March 2008 |
|
|
Staphylococcus aureus |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP00649
(show subtarget assignments)
|
1 |
in_pdb
3R2U |
No |
SACOL0046 |
57286601 |
|
metallo-beta-lactamase family protein |
442 |
Phase 2: March 2008 |
3R2U
|
100% |
Staphylococcus aureus |
Unknown function |
Enzymes of unknown specificity |
|
|
|
IDP00315
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
CBU_0874 |
29654200 |
aroC |
chorismate synthase |
352 |
Phase 2: March 2008 |
1R52
|
44.7% |
Coxiella burnetii |
Amino acid biosynthesis |
Aromatic amino acid family |
|
|
|
IDP00651
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL0143 |
57285346 |
cap5H |
capsular polysaccharide biosynthesis pro... |
208 |
Phase 2: March 2008 |
3EEV
|
33.2% |
Staphylococcus aureus |
Cell envelope |
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
|
|
|
IDP00652
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL0151 |
57285354 |
cap5P |
UDP-N-acetylglucosamine 2-epimerase Cap5... |
391 |
Phase 2: March 2008 |
1O6C
|
56% |
Staphylococcus aureus |
Cell envelope |
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
|
|
|
IDP00653
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL0451 |
57286824 |
ahpF |
alkyl hydroperoxide reductase, subunit F... |
507 |
Phase 2: March 2008 |
1HYU
|
53.8% |
Staphylococcus aureus |
Cellular processes |
Detoxification |
|
|
|
IDP00655
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL0536 |
57285561 |
ksgA |
dimethyladenosine transferase |
297 |
Phase 2: March 2008 |
3GRR
|
33.7% |
Staphylococcus aureus |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00656
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL0543 |
57284226 |
glmU |
UDP-N-acetylglucosamine pyrophosphorylas... |
450 |
Phase 2: March 2008 |
1G95
|
49.1% |
Staphylococcus aureus |
Cell envelope |
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
|
|
|
IDP00657
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL0761 |
57285726 |
nagA |
N-acetylglucosamine-6-phosphate deacetyl... |
393 |
Phase 2: March 2008 |
2VHL
|
45.8% |
Staphylococcus aureus |
Central intermediary metabolism |
Amino sugars |
|
|
|
IDP00634
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL1722 |
57284733 |
tig |
trigger factor |
433 |
Phase 2: March 2008 |
1W26
|
31.6% |
Staphylococcus aureus |
Protein fate |
Protein folding and stabilization |
|
|
|
IDP00633
(show subtarget assignments)
|
1 |
soluble |
No |
SACOL0118 |
57286667 |
sodA1 |
superoxide dismutase |
199 |
Phase 2: March 2008 |
1JR9
|
64.5% |
Staphylococcus aureus |
Cellular processes |
Detoxification |
|
|
|
IDP00314
(show subtarget assignments)
|
1 |
expressed |
No |
CBU_0751 |
29654085 |
murA |
UDP-N-acetylglucosamine 1-carboxyvinyltr... |
434 |
Phase 2: March 2008 |
1EJC
|
57.1% |
Coxiella burnetii |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP00140
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
BA_0197 |
30253704 |
|
pyrroline-5-carboxylate reductase, putat... |
245 |
Phase 1: October 2007 |
3TRI
|
33.7% |
Bacillus anthracis |
Purines, pyrimidines, nucleosides, and nucleotides |
Pyrimidine ribonucleotide biosynthesis |
|
|
|
IDP00662
(show subtarget assignments)
|
1 |
in_pdb
3KZW |
No |
SACOL0945 |
57285819 |
|
cytosol aminopeptidase |
491 |
Phase 2: March 2008 |
3KZW
|
100% |
Staphylococcus aureus |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP00663
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL0979 |
57285852 |
clpB |
ATP-dependent Clp protease, ATP-binding ... |
869 |
Phase 2: March 2008 |
1QVR
|
54.3% |
Staphylococcus aureus |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP00664
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL1028 |
57284400 |
htrA |
serine protease |
769 |
Phase 2: March 2008 |
2ZLE
|
12.7% |
Staphylococcus aureus |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP00665
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL1079 |
57285865 |
purF |
amidophosphoribosyltransferase |
494 |
Phase 2: March 2008 |
1AO0
|
51% |
Staphylococcus aureus |
Purines, pyrimidines, nucleosides, and nucleotides |
Purine ribonucleotide biosynthesis |
|
|
|
IDP00666
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL1096 |
57285882 |
|
TrkA potassium uptake family protein |
220 |
Phase 2: March 2008 |
2HMS
|
36.4% |
Staphylococcus aureus |
Transport and binding proteins |
Cations and iron carrying compounds |
|
|
|
IDP00667
(show subtarget assignments)
|
1 |
purified |
No |
SACOL1134 |
57285920 |
kdtB |
lipopolysaccharide core biosynthesis pro... |
160 |
Phase 2: March 2008 |
3F3M
|
100% |
Staphylococcus aureus |
Cell envelope |
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
|
|
|
IDP00668
(show subtarget assignments)
|
1 |
crystallized |
No |
SACOL1196 |
57284481 |
murD |
UDP-N-acetylmuramoyl-L-alanyl-D-glutamat... |
449 |
Phase 2: March 2008 |
3LK7
|
46.3% |
Staphylococcus aureus |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP00669
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL1199 |
57285942 |
ftsZ |
cell division protein FtsZ |
390 |
Phase 2: March 2008 |
2VAM
|
68.7% |
Staphylococcus aureus |
Cellular processes |
Cell division |
|
|
|
IDP00670
(show subtarget assignments)
|
1 |
purified |
No |
SACOL1212 |
57285955 |
pyrB |
aspartate carbamoyltransferase catalytic... |
293 |
Phase 2: March 2008 |
2AT2
|
55.6% |
Staphylococcus aureus |
Purines, pyrimidines, nucleosides, and nucleotides |
Pyrimidine ribonucleotide biosynthesis |
|
|
|
IDP00671
(show subtarget assignments)
|
1 |
purified |
No |
SACOL1215 |
57285958 |
carB |
carbamoyl phosphate synthase large subun... |
1057 |
Phase 2: March 2008 |
1BXR
|
49.6% |
Staphylococcus aureus |
Purines, pyrimidines, nucleosides, and nucleotides |
Pyrimidine ribonucleotide biosynthesis |
|
|
|
IDP00672
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL1271 |
57286009 |
hslU |
ATP-dependent protease ATP-binding subun... |
467 |
Phase 2: March 2008 |
1G3I
|
47.1% |
Staphylococcus aureus |
Protein fate |
Protein folding and stabilization |
|
|
|
IDP00673
(show subtarget assignments)
|
1 |
expressed |
No |
SACOL1322 |
57286057 |
|
hydrolase, alpha/beta hydrolase fold fam... |
304 |
Phase 2: March 2008 |
3HJU
|
24.7% |
Staphylococcus aureus |
Unknown function |
Enzymes of unknown specificity |
|
|
|
IDP00674
(show subtarget assignments)
|
1 |
crystallized |
No |
SACOL1453 |
57286104 |
murG |
N-acetylglucosaminyl transferase |
356 |
Phase 2: March 2008 |
1F0K
|
25.6% |
Staphylococcus aureus |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP00069
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
NTL01ST0342 |
16418853 |
STM0352 |
putative cation efflux pump |
408 |
Phase 1: October 2007 |
1T5E
|
31.1% |
Salmonella enterica |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00676
(show subtarget assignments)
|
1 |
expressed |
No |
SACOL1492 |
57284593 |
nth |
endonuclease III |
219 |
Phase 2: March 2008 |
1ORN
|
62.1% |
Staphylococcus aureus |
DNA metabolism |
DNA replication, recombination, and repair |
|
|
|
IDP00677
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL1588 |
57286110 |
|
proline dipeptidase |
353 |
Phase 2: March 2008 |
3Q6D
|
49.4% |
Staphylococcus aureus |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP00678
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL1624 |
57286146 |
era |
GTP-binding protein Era |
299 |
Phase 2: March 2008 |
3IEV
|
45.2% |
Staphylococcus aureus |
Cellular processes |
Cell division |
|
|
|
IDP00631
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL1537 |
57284636 |
scpB |
segregation and condensation protein B |
180 |
Phase 2: March 2008 |
1T6S
|
23.9% |
Staphylococcus aureus |
Cellular processes |
Cell division |
|
|
|
IDP00680
(show subtarget assignments)
|
1 |
purified |
No |
SACOL1721 |
57284732 |
clpX |
ATP-dependent protease ATP-binding subun... |
420 |
Phase 2: March 2008 |
3HWS
|
52.4% |
Staphylococcus aureus |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP00681
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL1756 |
57286191 |
pepQ |
proline dipeptidase |
351 |
Phase 2: March 2008 |
1WY2
|
41.3% |
Staphylococcus aureus |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP00682
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL1777 |
57286212 |
|
serine protease HtrA, putative |
424 |
Phase 2: March 2008 |
2ZLE
|
29% |
Staphylococcus aureus |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP00630
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL0861 |
57284322 |
|
cold shock protein, CSD family |
66 |
Phase 2: March 2008 |
2I5M
|
71.2% |
Staphylococcus aureus |
Cellular processes |
Adaptations to atypical conditions |
|
|
|
IDP00313
(show subtarget assignments)
|
1 |
expressed |
No |
CBU_0647 |
29653985 |
ribA |
riboflavin biosynthesis protein RibA |
406 |
Phase 2: March 2008 |
2BZ0
|
27.1% |
Coxiella burnetii |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Riboflavin, FMN, and FAD |
|
|
|
