(skip to main content)
Home
Target List
Selection
Community Requests
Clones
Screenings
XML files
Diffraction Images
Progress
Homolog Search
Clustering
Statistics
News
Help
Log In
Consortium
Overview
Investigators
Experiments
X-ray Structures
NMR Structures
Electronic Structure Description
Publications
Resources
Clustering
Related Sites
Progress
Collaborators
Basecamp
Contact Us
Log In
Targets
Filter Targets:
Selection Phase:
No Filter
Community Interest
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM10+
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
[Clostridium] difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
0
1
6
8
Keyword:
Type Keyword
Stage:
No Filter
cloned
crystallized
crystal_structure
diffraction
expressed
in_crystallization_trials
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Screening
No Filter
Yes
No
Remove Filters
Download data as tab-separated value (TSV) file
(which can be used as a input for Microsoft Office Excel and Open Office Calc)
Jump to Target:
In
IDP#
NCBI GI
LOCUS TAG
Search
Page 6 of 60, showing 100 records out of 5973 total, starting on record 501
previous
|
1
|
2
|
3
|
4
|
5
|
6
|
7
|
8
|
9
|
10
|
11
|
12
|
13
|
14
|
15
|
16
|
17
|
18
|
19
|
next
CSGID ID
Priority
stage
Screening
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP90418
(
show subtarget assignments
)
8
in_crystallization_trials
No
CT_466
3328900
hypothetical protein [Chlamydia trachoma...
109
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90417
(
show subtarget assignments
)
8
cloned
No
CT_504
3328941
hypothetical protein [Chlamydia trachoma...
288
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90422
(
show subtarget assignments
)
8
cloned
No
CT_471
3328905
hypothetical protein [Chlamydia trachoma...
200
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90421
(
show subtarget assignments
)
8
expressed
No
CT_433
3328864
hypothetical protein [Chlamydia trachoma...
223
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90424
(
show subtarget assignments
)
8
cloned
No
CT_546
3328985
predicted OMP [Chlamydia trachomatis D/U...
289
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90423
(
show subtarget assignments
)
8
cloned
No
CT_444
3328876
omcA
9kDa-Cysteine-Rich Lipoprotein [Chlamydi...
88
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90427
(
show subtarget assignments
)
8
cloned
No
CT_847
3329319
hypothetical protein [Chlamydia trachoma...
172
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90426
(
show subtarget assignments
)
8
cloned
No
CT_863
3329337
hypothetical protein [Chlamydia trachoma...
482
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90428
(
show subtarget assignments
)
8
cloned
No
CT_849
3329321
hypothetical protein [Chlamydia trachoma...
159
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90429
(
show subtarget assignments
)
8
cloned
No
CT_860
3329334
hypothetical protein [Chlamydia trachoma...
493
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP04326
(
show subtarget assignments
)
8
purified
No
CAC05800
12329069
ipaA
IpaA, secreted by the Mxi-Spa machinery,...
633
Shigella effector protein
Community Requests
2FM8
10.7%
Shigella flexneri
IDP90133
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_159
68449233
CD47-like putative membrane protein [Mon...
277
similar to VACV-COP-A38L, MPXV-ZAI96-A40L
Community Requests
2JJS
11.6%
Monkeypox virus
IDP90502
(
show subtarget assignments
)
8
purified
No
Q9KPA4
22653875
RecName: Full=L-aspartate oxidase; Short...
535
Predicted Essential
Community Requests
1CHU
75.3%
Vibrio cholerae
IDP90507
(
show subtarget assignments
)
8
soluble
No
VC2270
15642268
riboflavin synthase subunit alpha [Vibri...
217
Predicted Essential
Community Requests
1KZL
35.5%
Vibrio cholerae
IDP90515
(
show subtarget assignments
)
8
in_pdb
3ULW
No
Cj0884
15792215
rpsO
30S ribosomal protein S15 [Campylobacter...
90
Predicted Essential
Community Requests
3ULW
100%
Campylobacter jejuni
IDP02115
(
show subtarget assignments
)
1
purified
No
FTT0900
56708001
hypothetical protein FTT0900 [Francisell...
123
Drug Target
Community Requests
2GM2
22.8%
Francisella tularensis
Cell envelope
Other
IDP90531
(
show subtarget assignments
)
8
cloned
No
Q9KSF9
20139940
RecName: Full=Asparaginyl-tRNA synthetas...
466
Predicted Essential
Community Requests
1X54
35.2%
Vibrio cholerae
IDP90295
(
show subtarget assignments
)
8
cloned
No
TGME49_005290
211965425
dual-specificity phosphatase laforin, pu...
523
Human Lafora disease is one of five major progressive myoclonus epilepsies that ...
Community Requests
Toxoplasma gondii
IDP04002
(
show subtarget assignments
)
8
selected
No
CAC05806
12329075
ipgA
IpgA, similarities to IpgE, putative cha...
129
Shigella effector protein
Community Requests
Shigella flexneri
IDP04075
(
show subtarget assignments
)
8
selected
No
CAC05807
12329076
icsB
IcsB, function unknown [Shigella flexner...
494
Shigella effector protein
Community Requests
Shigella flexneri
IDP04066
(
show subtarget assignments
)
8
selected
No
CAC05819
12329088
mxiE
MxiE, similarities to transcriptional ac...
210
Shigella effector protein
Community Requests
Shigella flexneri
IDP04060
(
show subtarget assignments
)
8
selected
No
CAC05813
12329082
mxiI
MxiI, component of the Mxi-Spa secretion...
97
Shigella effector protein
Community Requests
Shigella flexneri
IDP90742
(
show subtarget assignments
)
8
crystallized
No
Cj0947c
15792276
hydrolase, carbon-nitrogen family [Campy...
290
Predicted Essential
Community Requests
3IVZ
34.1%
Campylobacter jejuni
IDP04117
(
show subtarget assignments
)
8
selected
No
CAC05825
12329094
spa13
spa13, component of the Mxi-Spa secretio...
112
Shigella effector protein
Community Requests
Shigella flexneri
IDP04222
(
show subtarget assignments
)
8
selected
No
CAC05827
12329096
spa33
Spa33, component of the Mxi-Spa secretio...
293
Shigella effector protein
Community Requests
Shigella flexneri
IDP04223
(
show subtarget assignments
)
8
selected
No
CAC05808
12329077
ipgD
IpgD, secreted by the Mxi-Spa machinery,...
538
Shigella effector protein
Community Requests
Shigella flexneri
IDP04336
(
show subtarget assignments
)
8
in_crystallization_trials
No
CAC05790
12329059
ospC1
OspC1, secreted by the Mxi-Spa secretion...
470
Shigella effector protein
Community Requests
Shigella flexneri
IDP04415
(
show subtarget assignments
)
8
selected
No
CAC05837
12329106
icsA (virG)
IcsA (VirG), outermembrane protein expos...
1102
Shigella effector protein
Community Requests
3ML3
15.2%
Shigella flexneri
IDP04414
(
show subtarget assignments
)
8
selected
No
CAC05786
12329055
sepA
SepA, extracellular serine protease of t...
1364
Shigella effector protein
Community Requests
1WXR
34.9%
Shigella flexneri
IDP04381
(
show subtarget assignments
)
8
selected
No
CAC05791
12329060
unnamed protein product [Shigella flexne...
296
Shigella effector protein
Community Requests
3MKL
8.4%
Shigella flexneri
IDP90746
(
show subtarget assignments
)
8
in_crystallization_trials
No
Cj0582
15791942
lysC
aspartate kinase [Campylobacter jejuni s...
400
Predicted Essential
Community Requests
3AB4
48.9%
Campylobacter jejuni
IDP04442
(
show subtarget assignments
)
8
soluble
No
YPO0494
115346303
b0053
survival protein SurA precursor (peptidy...
434
virulence/pathogenesis /
drug target; conserved gene; putative drug target function;
Community Requests
1M5Y
71%
Yersinia pestis
Protein fate
Protein folding and stabilization
IDP04534
(
show subtarget assignments
)
8
selected
No
CAC05815
12329084
mxiK
MxiK, putative component of the Mxi-Spa ...
175
Shigella effector protein
Community Requests
Shigella flexneri
IDP04535
(
show subtarget assignments
)
8
selected
No
CAC05816
12329085
mxiN
MxiN, putative component of the Mxi-Spa ...
231
Shigella effector protein
Community Requests
Shigella flexneri
IDP04558
(
show subtarget assignments
)
8
selected
No
CAC05811
12329080
mxiG
MxiG, component of the Mxi-Spa secretion...
371
Shigella effector protein
Community Requests
4A4Y
34%
Shigella flexneri
IDP04539
(
show subtarget assignments
)
8
in_crystallization_trials
No
CAC05775
12329044
ospD1
OspD1, secreted by the Mxi-Spa secretion...
225
Shigella effector protein
Community Requests
Shigella flexneri
IDP04627
(
show subtarget assignments
)
8
cloned
No
BAS5321
49188305
replicative DNA helicase [Bacillus anthr...
453
Proposed to be essential proteins
Community Requests
2VYE
75.3%
Bacillus anthracis
IDP04559
(
show subtarget assignments
)
8
selected
No
CAC05871
12329140
ospE1
OspE1, secreted by the Mxi-Spa secretion...
88
Shigella effector protein
Community Requests
Shigella flexneri
IDP90003
(
show subtarget assignments
)
8
crystallized
No
FTT1103
56708183
conserved hypothetical lipoprotein
365
(Community Request)
Community Requests
3GYK
12.3%
Francisella tularensis
IDP90001
(
show subtarget assignments
)
8
cloned
No
FTT0094c
56603762
qseC
sensor histidine kinase
475
Drug Target (Community Request)
Community Requests
3A0R
15.8%
Francisella tularensis
IDP90005
(
show subtarget assignments
)
8
soluble
No
Z4377
12517595
qseB
quorum sensing Escherichia coli regulato...
219
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3Q9S
41.1%
Escherichia coli
IDP90007
(
show subtarget assignments
)
8
cloned
No
Z4378
12517596
qseC
quorum sensing Escherichia coli regulato...
449
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3JZ3
47%
Escherichia coli
IDP00624
(
show subtarget assignments
)
8
in_pdb
3T41
3QFH
No
SACOL1874
57284795
epiP
epidermin leader peptide processing seri...
457
Drug Target Function
Community Requests
3QFH
94.1%
Staphylococcus aureus
Cellular processes
Toxin production and resistance
IDP90088
(
show subtarget assignments
)
8
soluble
No
ZZZ_0004
140
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90087
(
show subtarget assignments
)
8
cloned
No
ZZZ_0003
168
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90086
(
show subtarget assignments
)
8
expressed
No
ZZZ_0002
492
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90090
(
show subtarget assignments
)
8
expressed
No
ZZZ_0006
310
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90089
(
show subtarget assignments
)
8
expressed
No
ZZZ_0005
600
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90092
(
show subtarget assignments
)
8
purified
No
ZZZ_0008
155
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90091
(
show subtarget assignments
)
8
expressed
No
ZZZ_0007
660
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
2P5Z
15.6%
Escherichia coli
IDP90096
(
show subtarget assignments
)
8
expressed
No
ZZZ_0012
476
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90095
(
show subtarget assignments
)
8
soluble
No
ZZZ_0011
184
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90098
(
show subtarget assignments
)
8
purified
No
ZZZ_0014
196
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
3U66
19.4%
Escherichia coli
IDP90097
(
show subtarget assignments
)
8
cloned
No
ZZZ_0013
104
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90101
(
show subtarget assignments
)
8
in_crystallization_trials
No
STM2287
16765614
sseL
deubiquitinase [Salmonella typhimurium L...
317
SseL, is a ubiquitin isopeptidase that plays a critical role in the virulence an...
Community Requests
Salmonella enterica
IDP90100
(
show subtarget assignments
)
8
expressed
No
ZZZ_0016
849
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
1QVR
36.8%
Escherichia coli
IDP90102
(
show subtarget assignments
)
8
expressed
No
MPXV_ZAI1979_005_002
68449079
TNF-alpha-receptor-like protein [Monkeyp...
348
similar to VACV-COP-C22L/B28R, MPXV-ZAI96-J2L/J2R
Community Requests
3ON9
23.6%
Monkeypox virus
IDP90103
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_003
68449080
ankyrin-like protein [Monkeypox virus]
587
similar to VACV-COP-B25R/C19L, MPXV-ZAI96-J3L/J1R
Community Requests
Monkeypox virus
IDP90108
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_013
68449087
bifunctional zinc finger-like protein/E3...
242
similar to VARV BEN68-zinc finger-like protein
Community Requests
2ECW
8.3%
Monkeypox virus
IDP90111
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_017
68449091
ankyrin-like protein [Monkeypox virus]
630
similar to VACV-COP-C9L, MPXV-ZAI96-D9L
Community Requests
3NOC
5.1%
Monkeypox virus
IDP90110
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_015
68449089
ankyrin-like protein [Monkeypox virus]
660
similar to CPXV-GRI-C9L,CPXV-BR-V024, MPXV-ZAI96-D7L
Community Requests
1N0Q
4.4%
Monkeypox virus
IDP90109
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_014
68449088
interleukin-18-binding protein [Monkeypo...
126
similar to VACWR-C12L,VARV-BSH75_banu-D7L, MPXV-ZAI96-D6L
Community Requests
3F62
79.4%
Monkeypox virus
IDP90113
(
show subtarget assignments
)
8
expressed
No
MPXV_ZAI1979_005_021
68449095
unknown [Monkeypox virus]
315
similar to VACV-COP-C4L, MPXV-ZAI96-D13L
Community Requests
Monkeypox virus
IDP90112
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_019
68449093
unknown [Monkeypox virus]
153
similar to VACV-COP-C6L, MPXV-ZAI96-D11L
Community Requests
Monkeypox virus
IDP90114
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_023
68449097
kelch-like protein [Monkeypox virus]
105
similar to MPXV-ZAI96-D18L, part of VACV-COP-C2L
Community Requests
Monkeypox virus
IDP90115
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_024
68449098
kelch-like protein [Monkeypox virus]
176
similar to MPXV-ZAI96-D18L, part of VACV-COP-C2L
Community Requests
2XN4
26.1%
Monkeypox virus
IDP90120
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_030
68449104
unknown [Monkeypox virus]
220
similar to VACV-COP-M2L, MPXV-ZAI96-O2L
Community Requests
Monkeypox virus
IDP90119
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_029
68449103
ankyrin-like protein [Monkeypox virus]
442
similar to VACV-COP-M1L, MPXV-ZAI96-O1L
Community Requests
1N11
16.3%
Monkeypox virus
IDP90122
(
show subtarget assignments
)
8
expressed
No
MPXV_ZAI1979_005_032
68449106
serine protease inhibitor-likeprotein SP...
375
similar to VACV-COP-K2L, MPXV-ZAI96-C2L
Community Requests
3LW2
29.2%
Monkeypox virus
IDP90121
(
show subtarget assignments
)
8
purified
No
MPXV_ZAI1979_005_031
68449105
ankyrin-like protein [Monkeypox virus]
284
similar to VACV-COP-K1L, MPXV-ZAI96-C1L
Community Requests
3KEA
94.7%
Monkeypox virus
IDP90125
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_038
68449112
kelch-like protein [Monkeypox virus]
485
similar to VACV-COP-F3L, MPXV-ZAI96-C9L
Community Requests
1ZGK
13.6%
Monkeypox virus
IDP90124
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_036
68449110
unknown [Monkeypox virus]
219
mitochondrial-associated inhibitor of apoptosis, similar to VACV-COP-F1L, MPXV-Z...
Community Requests
2VTY
69.4%
Monkeypox virus
IDP90126
(
show subtarget assignments
)
8
expressed
No
MPXV_ZAI1979_005_044
68449118
unknown [Monkeypox virus]
212
thiol substrate, similar to VACV-COP-F9L, MPXV-ZAI96-C15L
Community Requests
1YPY
21.7%
Monkeypox virus
IDP90127
(
show subtarget assignments
)
8
expressed
No
MPXV_ZAI1979_005_045
68449119
ser/thr kinase [Monkeypox virus]
439
similar to VACV-COP-F10L, MPXV-ZAI96-C16L
Community Requests
Monkeypox virus
IDP90134
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_166
68449240
Toll/IL1-receptor [TIR]-like protein [Mo...
240
similar to VACV-COP-A46R, MPXV-ZAI96-A47R
Community Requests
Monkeypox virus
IDP90137
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_179
68449250
ankyrin-like protein [Monkeypox virus]
561
similar to VACV-COP-B4R, MPXV-ZAI96-B5R
Community Requests
1N11
11.2%
Monkeypox virus
IDP90136
(
show subtarget assignments
)
8
expressed
No
MPXV_ZAI1979_005_177
68449248
ser/thr kinase [Monkeypox virus]
299
essential for viral DNA replication, similar to VACV-COP-B1R, MPXV-ZAI96-B3R
Community Requests
2V62
40.4%
Monkeypox virus
IDP90135
(
show subtarget assignments
)
8
expressed
No
MPXV_ZAI1979_005_174
68449246
kelch-like protein [Monkeypox virus]
82
similar to part of VACV-COP-A55R, MPXV-ZAI96-B1R
Community Requests
Monkeypox virus
IDP90138
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_181
68449252
ankyrin-like protein [Monkeypox virus]
119
similar to VACV-COP-B6R, MPXV-ZAI96-B7R
Community Requests
Monkeypox virus
IDP90141
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_186
68449257
ser/thr protein kinase-like protein [Mon...
282
similar to VACV-COP-B12R, MPXV-ZAI96-B11R
Community Requests
2KTY
32.4%
Monkeypox virus
IDP90140
(
show subtarget assignments
)
8
expressed
No
MPXV_ZAI1979_005_184
68449255
6kDa intracellular viral protein [Monkey...
221
similar to VACV-COP-B9R, MPXV-ZAI96-B10R
Community Requests
Monkeypox virus
IDP90139
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_182
68449253
bifunctional 21kDa precursor protein of ...
182
virulence, ER resident, similar to VACV-COP-B7R, N-terminal signal peptide, bifu...
Community Requests
Monkeypox virus
IDP90144
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_189.5
68449261
bifunctional IL-1-beta-inhibitor/prevent...
126
contains IG fold, similar to VACV-WR-197, MPXV-ZAR_1979_005-184
Community Requests
1G0Y
27.8%
Monkeypox virus
IDP90143
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_189
68449260
bifunctional IL-1-beta-inhibitor/prevent...
210
contains IG fold, similar to VACV-WR-197, MPXV-ZAR_1979_005-184
Community Requests
3O4O
29.5%
Monkeypox virus
IDP90146
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_193
68449265
ankyrin-like protein [Monkeypox virus]
789
similar to VACV-COP-B20R, MPXV-ZAI96-B17R
Community Requests
1MJ0
5.2%
Monkeypox virus
IDP90145
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_192
68449264
IFN-alpha/beta-receptor-like secreted gl...
352
similar to VACV-COP-B19R, MPXV-ZAI96-B16R
Community Requests
3OQ3
83.2%
Monkeypox virus
IDP90149
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_195.5
68449268
serine protease inhibitor-like SPI-1 pro...
357
similar to part of VACV-COP-C12L, MPXV-ZAI96-B19R
Community Requests
1F0C
42%
Monkeypox virus
IDP90148
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_195
68449267
serine protease inhibitor-like SPI-1 pro...
71
similar to part of VACV-COP-C12L, MPXV-ZAI96-B19R
Community Requests
Monkeypox virus
IDP90150
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_202
68449275
unknown [Monkeypox virus]
176
similar to CPXV-GRI-C2L, MPXV-ZAI96-N3R
Community Requests
Monkeypox virus
IDP90161
(
show subtarget assignments
)
8
purified
No
CD1835
123174273
Chorismate synthase (5-enolpyruvylshikim...
359
Potential drug target. Shikimate pathway enzyme
Community Requests
1UM0
38.7%
Clostridium difficile
IDP90166
(
show subtarget assignments
)
8
soluble
No
CD1837
126699446
aroE
shikimate dehydrogenase [Clostridium dif...
269
Potential drug target. Shikimate pathway enzyme
Community Requests
3FBT
42%
Clostridium difficile
IDP90170
(
show subtarget assignments
)
8
selected
No
AAM13458.1
20152997
CPXV011 CDS
CPXV011 protein
658
ankyrin repeat protein
Community Requests
Cowpox virus
conserved hypothetical proteins
0
IDP90169
(
show subtarget assignments
)
8
expressed
No
AAM13454.1
20152993
CPXV008 CDS
CPXV008 protein
672
Potential drug target. Shikimate pathway enzyme
Community Requests
Cowpox virus
conserved hypothetical proteins
0
IDP90167
(
show subtarget assignments
)
8
purified
No
CD1838
123066836
Shikimate kinase
177
Potential drug target. Shikimate pathway enzyme
Community Requests
2PT5
31.6%
Clostridium difficile
IDP90172
(
show subtarget assignments
)
8
cloned
No
AAM13463.1
20153002
CPXV016 CDS
CPXV016 protein
764
ankyrin repeat protein
Community Requests
Cowpox virus
conserved hypothetical proteins
0
IDP90171
(
show subtarget assignments
)
8
cloned
No
AAM13460.1
20152999
CPXV013 CDS
CPXV013 protein
523
kelch-like protein
Community Requests
3HVE
10.1%
Cowpox virus
conserved hypothetical proteins
0
IDP90173
(
show subtarget assignments
)
8
cloned
No
AAM13464.1
20153003
CPXV017 CDS
CPXV017 protein
435
ankyrin repeat protein
Community Requests
2BKG
9.9%
Cowpox virus
conserved hypothetical proteins
0
IDP90174
(
show subtarget assignments
)
8
cloned
No
AAM13466.1
20153005
CPXV019 CDS
CPXV019 protein
796
ankyrin repeat protein
Community Requests
3HG0
3.8%
Cowpox virus
conserved hypothetical proteins
0
IDP90748
(
show subtarget assignments
)
8
in_pdb
3R0S
Yes
Cj0274
15791645
lpxA
UDP-N-acetylglucosamine acyltransferase ...
263
Predicted Essential
Community Requests
3R0S
100%
Campylobacter jejuni
IDP90747
(
show subtarget assignments
)
8
soluble
No
Cj0001
15791400
dnaA
chromosomal replication initiation prote...
440
Predicted Essential
Community Requests
2Z4R
34.3%
Campylobacter jejuni
previous
|
1
|
2
|
3
|
4
|
5
|
6
|
7
|
8
|
9
|
10
|
11
|
12
|
13
|
14
|
15
|
16
|
17
|
18
|
19
|
next
Filter Columns
Filter Columns:
Target Id
Locus Tag
Priority
Stage
Has Screening
Ncbi Gi
Gene Name
Common Name
Length
Justification
Project
Homolog Pdb Id
Homolog Sequence Identity
Organism
Tigr Main Role
Tigr Sub Role