|
|---|
| CSGID ID |
Priority |
stage |
Screening |
Locus Tag |
NCBI GI |
Gene
Name |
Common Name |
Sequence
Length |
Selection
Phase |
Homolog
PDB ID |
Homolog
Sequence
Identity |
Target Organism |
TIGR Main Role |
TIGR Subrole |
Request Person |
IDP00579
(show subtarget assignments)
|
1 |
cloned |
No |
YPO1122 |
16121422 |
tolR |
colicin uptake protein TolR |
142 |
Phase 2: March 2008 |
2JWK
|
23.9% |
Yersinia pestis |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00580
(show subtarget assignments)
|
1 |
purified |
No |
YPO0059 |
16120412 |
kbl |
2-amino-3-ketobutyrate coenzyme A ligase... |
403 |
Phase 2: March 2008 |
1FC4
|
82.9% |
Yersinia pestis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Biotin |
|
|
|
IDP00581
(show subtarget assignments)
|
1 |
in_pdb
3RDW |
Yes |
YPO3070 |
16123247 |
|
putative arsenate reductase |
118 |
Phase 2: March 2008 |
3RDW
|
100% |
Yersinia pestis |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00582
(show subtarget assignments)
|
1 |
in_pdb
3GSE |
Yes |
YPO2528 |
16122747 |
menF |
menaquinone-specific isochorismate synth... |
455 |
Phase 2: March 2008 |
3GSE
|
100% |
Yersinia pestis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Menaquinone and ubiquinone |
|
|
|
IDP00583
(show subtarget assignments)
|
1 |
expressed |
No |
YPO2752 |
16122956 |
mepA |
penicillin-insensitive murein endopeptid... |
275 |
Phase 2: March 2008 |
1TZP
|
67.6% |
Yersinia pestis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP00584
(show subtarget assignments)
|
1 |
soluble |
No |
YPO0117 |
16120462 |
metF |
5,10-methylenetetrahydrofolate reductase... |
294 |
Phase 2: March 2008 |
1ZP3
|
86.4% |
Yersinia pestis |
Amino acid biosynthesis |
Aspartate family |
|
|
|
IDP00585
(show subtarget assignments)
|
1 |
expressed |
No |
YPO0116 |
16120461 |
metL |
bifunctional aspartate kinase II/homoser... |
811 |
Phase 2: March 2008 |
1EBF
|
15.5% |
Yersinia pestis |
Amino acid biosynthesis |
Aspartate family |
|
|
|
IDP00586
(show subtarget assignments)
|
1 |
purified |
No |
YPO3789 |
16123923 |
metR |
lysR-family transcriptional regulatory p... |
317 |
Phase 2: March 2008 |
1AL3
|
23.7% |
Yersinia pestis |
Amino acid biosynthesis |
Aspartate family |
|
|
|
IDP00587
(show subtarget assignments)
|
1 |
cloned |
No |
YPO1507 |
16121780 |
mglB |
galactose-binding protein |
335 |
Phase 2: March 2008 |
1GCA
|
80.9% |
Yersinia pestis |
Transport and binding proteins |
Carbohydrates, organic alcohols, and acids |
|
|
|
IDP00588
(show subtarget assignments)
|
1 |
purified |
No |
YPO2077 |
16122316 |
minD |
cell division inhibitor MinD |
270 |
Phase 2: March 2008 |
3Q9L
|
87.8% |
Yersinia pestis |
Cellular processes |
Cell division |
|
|
|
IDP00589
(show subtarget assignments)
|
1 |
soluble |
No |
YPO0954 |
161486886 |
mltC |
membrane-bound lytic murein transglycosy... |
358 |
Phase 2: March 2008 |
2Y8P
|
19.3% |
Yersinia pestis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP00590
(show subtarget assignments)
|
1 |
cloned |
No |
YPO1078 |
16121379 |
mltD |
predicted membrane-bound lytic murein tr... |
475 |
Phase 2: March 2008 |
1E0G
|
7.8% |
Yersinia pestis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP00591
(show subtarget assignments)
|
1 |
cloned |
No |
YPO0145 |
161486893 |
mrcA |
penicillin-binding protein |
859 |
Phase 2: March 2008 |
3UDF
|
36.2% |
Yersinia pestis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP00592
(show subtarget assignments)
|
1 |
cloned |
No |
YPO3393 |
16123542 |
mrcB |
penicillin-binding protein 1b |
824 |
Phase 2: March 2008 |
3VMA
|
66.7% |
Yersinia pestis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP00593
(show subtarget assignments)
|
1 |
expressed |
No |
YPO1232 |
16121518 |
msgA |
putative stress response protein |
80 |
Phase 2: March 2008 |
1GHH
|
30.5% |
Yersinia pestis |
Cellular processes |
Pathogenesis |
|
|
|
IDP00594
(show subtarget assignments)
|
0 |
work_stopped |
No |
YPO3569 |
16123713 |
murA |
UDP-N-acetylglucosamine 1-carboxyvinyltr... |
420 |
Phase 2: March 2008 |
1NAW
|
91.7% |
Yersinia pestis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP00595
(show subtarget assignments)
|
1 |
crystallized |
No |
YPO3760 |
16123897 |
murB |
UDP-N-acetylenolpyruvoylglucosamine redu... |
345 |
Phase 2: March 2008 |
1MBB
|
60.9% |
Yersinia pestis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP00596
(show subtarget assignments)
|
1 |
purified |
No |
YPO0555 |
16120883 |
murG |
N-acetylglucosaminyl transferase |
356 |
Phase 2: March 2008 |
1F0K
|
78.4% |
Yersinia pestis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP00597
(show subtarget assignments)
|
1 |
purified |
No |
YPO3909 |
16124041 |
murI |
glutamate racemase |
287 |
Phase 2: March 2008 |
2JFN
|
71.4% |
Yersinia pestis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP00600
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL0532 |
57285557 |
|
hypothetical protein SACOL0532 |
51 |
Phase 2: March 2008 |
|
|
Staphylococcus aureus |
0 |
0 |
|
|
|
IDP00601
(show subtarget assignments)
|
1 |
purified |
No |
SACOL0893 |
57284352 |
|
pathogenicity island protein |
48 |
Phase 2: March 2008 |
|
|
Staphylococcus aureus |
Cellular processes |
Pathogenesis |
|
|
|
IDP00602
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL0903 |
57285779 |
|
pathogenicity island protein |
72 |
Phase 2: March 2008 |
2L8T
|
95.8% |
Staphylococcus aureus |
Cellular processes |
Pathogenesis |
|
|
|
IDP00603
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL0726 |
57285695 |
sarX |
staphylococcal accessory protein X |
141 |
Phase 2: March 2008 |
|
|
Staphylococcus aureus |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00604
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL1610 |
57286132 |
sodA2 |
superoxide dismutase |
199 |
Phase 2: March 2008 |
2RCV
|
71.8% |
Staphylococcus aureus |
Cellular processes |
Detoxification |
|
|
|
IDP00605
(show subtarget assignments)
|
0 |
work_stopped |
No |
SACOL1745 |
57284754 |
pyk |
pyruvate kinase |
585 |
Phase 2: March 2008 |
3T05
|
99.5% |
Staphylococcus aureus |
Energy metabolism |
Glycolysis/gluconeogenesis |
|
|
|
IDP00606
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL1933 |
57286280 |
|
ThiJ/PfpI family protein |
171 |
Phase 2: March 2008 |
1OI4
|
48.8% |
Staphylococcus aureus |
Unknown function |
General |
|
|
|
IDP00607
(show subtarget assignments)
|
1 |
soluble |
No |
SACOL2116 |
57286332 |
murAB |
UDP-N-acetylglucosamine 1-carboxyvinyltr... |
419 |
Phase 2: March 2008 |
3SG1
|
47% |
Staphylococcus aureus |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP00608
(show subtarget assignments)
|
1 |
expressed |
No |
SACOL0127 |
57285334 |
|
phosphonate ABC transporter, ATP-binding... |
257 |
Phase 2: March 2008 |
1F3O
|
35% |
Staphylococcus aureus |
Transport and binding proteins |
Other |
|
|
|
IDP00609
(show subtarget assignments)
|
1 |
expressed |
No |
SACOL0690 |
57285660 |
|
ABC transporter, ATP-binding protein |
247 |
Phase 2: March 2008 |
3D31
|
29.1% |
Staphylococcus aureus |
Transport and binding proteins |
Unknown substrate |
|
|
|
IDP00610
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL1437 |
57286088 |
|
cold shock protein, CSD family |
66 |
Phase 2: March 2008 |
1CSP
|
75.8% |
Staphylococcus aureus |
Cellular processes |
Adaptations to atypical conditions |
|
|
|
IDP00611
(show subtarget assignments)
|
1 |
crystallized |
No |
SACOL1952 |
57286299 |
|
ferritins family protein |
166 |
Phase 2: March 2008 |
2JD6
|
39.2% |
Staphylococcus aureus |
Transport and binding proteins |
Cations and iron carrying compounds |
|
|
|
IDP00612
(show subtarget assignments)
|
1 |
purified |
No |
SACOL0582 |
57285598 |
nusG |
transcription antitermination protein Nu... |
182 |
Phase 2: March 2008 |
2JVV
|
40.7% |
Staphylococcus aureus |
Transcription |
Transcription factors |
|
|
|
IDP00613
(show subtarget assignments)
|
1 |
soluble |
No |
SACOL1377 |
57284532 |
tkt |
transketolase |
662 |
Phase 2: March 2008 |
3HYL
|
61.2% |
Staphylococcus aureus |
Energy metabolism |
Pentose phosphate pathway |
|
|
|
IDP00614
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL2109 |
57286325 |
|
modification methylase, HemK family |
278 |
Phase 2: March 2008 |
1T43
|
32% |
Staphylococcus aureus |
Unknown function |
General |
|
|
|
IDP00615
(show subtarget assignments)
|
1 |
expressed |
No |
SACOL1160 |
57284445 |
sdhB |
succinate dehydrogenase iron-sulfur subu... |
271 |
Phase 2: March 2008 |
1E7P
|
25.1% |
Staphylococcus aureus |
Energy metabolism |
TCA cycle |
|
|
|
IDP00616
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL1586 |
57286108 |
|
hypothetical protein SACOL1586 |
94 |
Phase 2: March 2008 |
|
|
Staphylococcus aureus |
0 |
0 |
|
|
|
IDP00617
(show subtarget assignments)
|
1 |
expressed |
No |
SACOL1880 |
57284800 |
lukD |
leukotoxin LukD |
327 |
Phase 2: March 2008 |
1PVL
|
75.5% |
Staphylococcus aureus |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00618
(show subtarget assignments)
|
1 |
purified |
No |
SACOL2348 |
57285082 |
|
drug transporter, putative |
215 |
Phase 2: March 2008 |
|
|
Staphylococcus aureus |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00619
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL2464 |
57286459 |
|
addiction module toxin, Txe/YoeB family ... |
88 |
Phase 2: March 2008 |
|
|
Staphylococcus aureus |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00620
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL0937 |
57285812 |
dltC |
D-alanine--poly(phosphoribitol) ligase s... |
78 |
Phase 2: March 2008 |
1DV5
|
41% |
Staphylococcus aureus |
Cell envelope |
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
|
|
|
IDP00621
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL2217 |
57284998 |
infA |
translation initiation factor IF-1 |
72 |
Phase 2: March 2008 |
3I4O
|
69.9% |
Staphylococcus aureus |
Protein synthesis |
Translation factors |
|
|
|
IDP00622
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL1878 |
57284798 |
epiA |
lantibiotic epidermin precursor EpiA |
47 |
Phase 2: March 2008 |
|
|
Staphylococcus aureus |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00623
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL2731 |
57285285 |
|
cold shock protein, CSD family |
66 |
Phase 2: March 2008 |
2I5M
|
68.2% |
Staphylococcus aureus |
Cellular processes |
Adaptations to atypical conditions |
|
|
|
IDP00624
(show subtarget assignments)
|
8 |
in_pdb
3T41
3QFH |
No |
SACOL1874 |
57284795 |
epiP |
epidermin leader peptide processing seri... |
457 |
Community Requests |
3QFH
|
94.1% |
Staphylococcus aureus |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00625
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL2404 |
57285135 |
|
addiction module toxin, Txe/YoeB family ... |
88 |
Phase 2: March 2008 |
2A6Q
|
51.1% |
Staphylococcus aureus |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00626
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL2506 |
57285191 |
sarT |
staphylococcal accessory regulator T |
118 |
Phase 2: March 2008 |
2FNP
|
33.1% |
Staphylococcus aureus |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00627
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL0552 |
57285570 |
|
hypothetical protein SACOL0552 |
133 |
Phase 2: March 2008 |
2K4K
|
40.6% |
Staphylococcus aureus |
Cellular processes |
Adaptations to atypical conditions |
|
|
|
IDP00628
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL0369 |
57285482 |
|
prophage L54a, Clp protease, putative |
257 |
Phase 2: March 2008 |
1Y7O
|
22.2% |
Staphylococcus aureus |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP00629
(show subtarget assignments)
|
1 |
in_pdb
3QJG |
No |
SACOL1875 |
57284796 |
epiD |
epidermin biosynthesis protein EpiD |
172 |
Phase 2: March 2008 |
3QJG
|
100% |
Staphylococcus aureus |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00630
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL0861 |
57284322 |
|
cold shock protein, CSD family |
66 |
Phase 2: March 2008 |
2I5M
|
71.2% |
Staphylococcus aureus |
Cellular processes |
Adaptations to atypical conditions |
|
|
|
IDP00631
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL1537 |
57284636 |
scpB |
segregation and condensation protein B |
180 |
Phase 2: March 2008 |
1T6S
|
23.9% |
Staphylococcus aureus |
Cellular processes |
Cell division |
|
|
|
IDP00633
(show subtarget assignments)
|
1 |
soluble |
No |
SACOL0118 |
57286667 |
sodA1 |
superoxide dismutase |
199 |
Phase 2: March 2008 |
1JR9
|
64.5% |
Staphylococcus aureus |
Cellular processes |
Detoxification |
|
|
|
IDP00634
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL1722 |
57284733 |
tig |
trigger factor |
433 |
Phase 2: March 2008 |
1W26
|
31.6% |
Staphylococcus aureus |
Protein fate |
Protein folding and stabilization |
|
|
|
IDP00635
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL2270 |
57286396 |
modC |
molybdenum ABC transporter, ATP-binding ... |
201 |
Phase 2: March 2008 |
2IT1
|
38.8% |
Staphylococcus aureus |
Transport and binding proteins |
Anions |
|
|
|
IDP00636
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL1118 |
57285904 |
typA |
GTP-binding protein TypA |
615 |
Phase 2: March 2008 |
3E3X
|
27.6% |
Staphylococcus aureus |
Unknown function |
General |
|
|
|
IDP00637
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL1727 |
57284738 |
infC |
translation initiation factor IF-3 |
175 |
Phase 2: March 2008 |
1TIG
|
37.7% |
Staphylococcus aureus |
Protein synthesis |
Translation factors |
|
|
|
IDP00638
(show subtarget assignments)
|
1 |
purified |
No |
SACOL2736 |
57285290 |
gidB |
glucose-inhibited division protein B |
239 |
Phase 2: March 2008 |
1XDZ
|
63.2% |
Staphylococcus aureus |
Unknown function |
General |
|
|
|
IDP00639
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL0114 |
57286663 |
|
capsular polysaccharide biosynthesis gly... |
230 |
Phase 2: March 2008 |
|
|
Staphylococcus aureus |
Cell envelope |
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
|
|
|
IDP00640
(show subtarget assignments)
|
1 |
in_pdb
3EME
3MZZ |
No |
SACOL1807 |
57286241 |
|
rhodanese-like domain protein |
103 |
Phase 2: March 2008 |
3EME
|
100% |
Staphylococcus aureus |
Unknown function |
General |
|
|
|
IDP00641
(show subtarget assignments)
|
1 |
purified |
No |
SACOL1866 |
57284787 |
|
serine protease SplD, putative |
239 |
Phase 2: March 2008 |
2VID
|
43.5% |
Staphylococcus aureus |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP00642
(show subtarget assignments)
|
1 |
soluble |
No |
SACOL2384 |
57285116 |
sarZ |
staphylococcal accessory protein Z |
148 |
Phase 2: March 2008 |
3HRM
|
91.9% |
Staphylococcus aureus |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00643
(show subtarget assignments)
|
1 |
purified |
No |
SACOL2638 |
57286542 |
|
precorrin-2 dehydrogenase |
201 |
Phase 2: March 2008 |
3DFZ
|
33.8% |
Staphylococcus aureus |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Heme, porphyrin, and cobalamin |
|
|
|
IDP00644
(show subtarget assignments)
|
1 |
expressed |
No |
SACOL0220 |
57286684 |
|
flavohemoprotein, putative |
381 |
Phase 2: March 2008 |
1CQX
|
36.9% |
Staphylococcus aureus |
Unknown function |
General |
|
|
|
IDP00646
(show subtarget assignments)
|
1 |
selected |
No |
SACOL0887 |
57284346 |
sei |
staphylococcal enterotoxin type I |
242 |
Phase 2: March 2008 |
2G9H
|
55% |
Staphylococcus aureus |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00647
(show subtarget assignments)
|
1 |
selected |
No |
SACOL1657 |
57286179 |
|
enterotoxin type A, putative |
234 |
Phase 2: March 2008 |
1ESF
|
40.2% |
Staphylococcus aureus |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00648
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL2160 |
57286373 |
|
hemolysin III, putative |
227 |
Phase 2: March 2008 |
|
|
Staphylococcus aureus |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP00649
(show subtarget assignments)
|
1 |
in_pdb
3R2U |
No |
SACOL0046 |
57286601 |
|
metallo-beta-lactamase family protein |
442 |
Phase 2: March 2008 |
3R2U
|
100% |
Staphylococcus aureus |
Unknown function |
Enzymes of unknown specificity |
|
|
|
IDP00650
(show subtarget assignments)
|
1 |
soluble |
No |
SACOL0113 |
57286662 |
|
NAD-dependent epimerase/dehydratase fami... |
323 |
Phase 2: March 2008 |
1SB8
|
36.2% |
Staphylococcus aureus |
Cell envelope |
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
|
|
|
IDP00651
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL0143 |
57285346 |
cap5H |
capsular polysaccharide biosynthesis pro... |
208 |
Phase 2: March 2008 |
3EEV
|
33.2% |
Staphylococcus aureus |
Cell envelope |
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
|
|
|
IDP00652
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL0151 |
57285354 |
cap5P |
UDP-N-acetylglucosamine 2-epimerase Cap5... |
391 |
Phase 2: March 2008 |
1O6C
|
56% |
Staphylococcus aureus |
Cell envelope |
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
|
|
|
IDP00653
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL0451 |
57286824 |
ahpF |
alkyl hydroperoxide reductase, subunit F... |
507 |
Phase 2: March 2008 |
1HYU
|
53.8% |
Staphylococcus aureus |
Cellular processes |
Detoxification |
|
|
|
IDP00655
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL0536 |
57285561 |
ksgA |
dimethyladenosine transferase |
297 |
Phase 2: March 2008 |
3GRR
|
33.7% |
Staphylococcus aureus |
Cellular processes |
Toxin production and resistance |
|
|
|
IDP00656
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL0543 |
57284226 |
glmU |
UDP-N-acetylglucosamine pyrophosphorylas... |
450 |
Phase 2: March 2008 |
1G95
|
49.1% |
Staphylococcus aureus |
Cell envelope |
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
|
|
|
IDP00657
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL0761 |
57285726 |
nagA |
N-acetylglucosamine-6-phosphate deacetyl... |
393 |
Phase 2: March 2008 |
2VHL
|
45.8% |
Staphylococcus aureus |
Central intermediary metabolism |
Amino sugars |
|
|
|
IDP00658
(show subtarget assignments)
|
0 |
work_stopped |
No |
SACOL0801 |
57285762 |
murB |
UDP-N-acetylenolpyruvoylglucosamine redu... |
307 |
Phase 2: March 2008 |
1HSK
|
99.3% |
Staphylococcus aureus |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP00659
(show subtarget assignments)
|
1 |
soluble |
No |
SACOL0806 |
57285767 |
pepT |
peptidase T |
408 |
Phase 2: March 2008 |
3IFE
|
55.9% |
Staphylococcus aureus |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP00660
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL0816 |
57284278 |
secA |
preprotein translocase subunit SecA |
843 |
Phase 2: March 2008 |
1TF2
|
60.4% |
Staphylococcus aureus |
Protein fate |
Protein and peptide secretion and trafficking |
|
|
|
IDP00661
(show subtarget assignments)
|
1 |
purified |
No |
SACOL0827 |
57284289 |
|
acetyltransferase, putative |
161 |
Phase 2: March 2008 |
1OCX
|
30.4% |
Staphylococcus aureus |
Unknown function |
Enzymes of unknown specificity |
|
|
|
IDP00662
(show subtarget assignments)
|
1 |
in_pdb
3KZW |
No |
SACOL0945 |
57285819 |
|
cytosol aminopeptidase |
491 |
Phase 2: March 2008 |
3KZW
|
100% |
Staphylococcus aureus |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP00663
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL0979 |
57285852 |
clpB |
ATP-dependent Clp protease, ATP-binding ... |
869 |
Phase 2: March 2008 |
1QVR
|
54.3% |
Staphylococcus aureus |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP00664
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL1028 |
57284400 |
htrA |
serine protease |
769 |
Phase 2: March 2008 |
2ZLE
|
12.7% |
Staphylococcus aureus |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP00665
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL1079 |
57285865 |
purF |
amidophosphoribosyltransferase |
494 |
Phase 2: March 2008 |
1AO0
|
51% |
Staphylococcus aureus |
Purines, pyrimidines, nucleosides, and nucleotides |
Purine ribonucleotide biosynthesis |
|
|
|
IDP00666
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL1096 |
57285882 |
|
TrkA potassium uptake family protein |
220 |
Phase 2: March 2008 |
2HMS
|
36.4% |
Staphylococcus aureus |
Transport and binding proteins |
Cations and iron carrying compounds |
|
|
|
IDP00667
(show subtarget assignments)
|
1 |
purified |
No |
SACOL1134 |
57285920 |
kdtB |
lipopolysaccharide core biosynthesis pro... |
160 |
Phase 2: March 2008 |
3F3M
|
100% |
Staphylococcus aureus |
Cell envelope |
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
|
|
|
IDP00668
(show subtarget assignments)
|
1 |
crystallized |
No |
SACOL1196 |
57284481 |
murD |
UDP-N-acetylmuramoyl-L-alanyl-D-glutamat... |
449 |
Phase 2: March 2008 |
3LK7
|
46.3% |
Staphylococcus aureus |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP00669
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL1199 |
57285942 |
ftsZ |
cell division protein FtsZ |
390 |
Phase 2: March 2008 |
2VAM
|
68.7% |
Staphylococcus aureus |
Cellular processes |
Cell division |
|
|
|
IDP00670
(show subtarget assignments)
|
1 |
purified |
No |
SACOL1212 |
57285955 |
pyrB |
aspartate carbamoyltransferase catalytic... |
293 |
Phase 2: March 2008 |
2AT2
|
55.6% |
Staphylococcus aureus |
Purines, pyrimidines, nucleosides, and nucleotides |
Pyrimidine ribonucleotide biosynthesis |
|
|
|
IDP00671
(show subtarget assignments)
|
1 |
purified |
No |
SACOL1215 |
57285958 |
carB |
carbamoyl phosphate synthase large subun... |
1057 |
Phase 2: March 2008 |
1BXR
|
49.6% |
Staphylococcus aureus |
Purines, pyrimidines, nucleosides, and nucleotides |
Pyrimidine ribonucleotide biosynthesis |
|
|
|
IDP00672
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL1271 |
57286009 |
hslU |
ATP-dependent protease ATP-binding subun... |
467 |
Phase 2: March 2008 |
1G3I
|
47.1% |
Staphylococcus aureus |
Protein fate |
Protein folding and stabilization |
|
|
|
IDP00673
(show subtarget assignments)
|
1 |
expressed |
No |
SACOL1322 |
57286057 |
|
hydrolase, alpha/beta hydrolase fold fam... |
304 |
Phase 2: March 2008 |
3HJU
|
24.7% |
Staphylococcus aureus |
Unknown function |
Enzymes of unknown specificity |
|
|
|
IDP00674
(show subtarget assignments)
|
1 |
crystallized |
No |
SACOL1453 |
57286104 |
murG |
N-acetylglucosaminyl transferase |
356 |
Phase 2: March 2008 |
1F0K
|
25.6% |
Staphylococcus aureus |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP00675
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL1455 |
57284564 |
|
carboxyl-terminal protease |
496 |
Phase 2: March 2008 |
1FC6
|
20% |
Staphylococcus aureus |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP00676
(show subtarget assignments)
|
1 |
expressed |
No |
SACOL1492 |
57284593 |
nth |
endonuclease III |
219 |
Phase 2: March 2008 |
1ORN
|
62.1% |
Staphylococcus aureus |
DNA metabolism |
DNA replication, recombination, and repair |
|
|
|
IDP00677
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL1588 |
57286110 |
|
proline dipeptidase |
353 |
Phase 2: March 2008 |
3Q6D
|
49.4% |
Staphylococcus aureus |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP00678
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL1624 |
57286146 |
era |
GTP-binding protein Era |
299 |
Phase 2: March 2008 |
3IEV
|
45.2% |
Staphylococcus aureus |
Cellular processes |
Cell division |
|
|
|
IDP00679
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL1699 |
57284711 |
obgE |
GTPase ObgE |
430 |
Phase 2: March 2008 |
1LNZ
|
54.2% |
Staphylococcus aureus |
Unknown function |
General |
|
|
|
IDP00680
(show subtarget assignments)
|
1 |
purified |
No |
SACOL1721 |
57284732 |
clpX |
ATP-dependent protease ATP-binding subun... |
420 |
Phase 2: March 2008 |
3HWS
|
52.4% |
Staphylococcus aureus |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP00681
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
SACOL1756 |
57286191 |
pepQ |
proline dipeptidase |
351 |
Phase 2: March 2008 |
1WY2
|
41.3% |
Staphylococcus aureus |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP00682
(show subtarget assignments)
|
1 |
cloned |
No |
SACOL1777 |
57286212 |
|
serine protease HtrA, putative |
424 |
Phase 2: March 2008 |
2ZLE
|
29% |
Staphylococcus aureus |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP00683
(show subtarget assignments)
|
1 |
purified |
No |
SACOL1795 |
57286229 |
pepA1 |
glutamyl aminopeptidase |
358 |
Phase 2: March 2008 |
3KL9
|
38.8% |
Staphylococcus aureus |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
