|
|---|
| CSGID ID |
Priority |
stage |
Screening |
Locus Tag |
NCBI GI |
Gene
Name |
Common Name |
Sequence
Length |
Selection
Phase |
Homolog
PDB ID |
Homolog
Sequence
Identity |
Target Organism |
TIGR Main Role |
TIGR Subrole |
Request Person |
IDP02833
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA4561 |
47529857 |
aroE |
shikimate 5-dehydrogenase [Bacillus anth... |
308 |
Phase 3: June 2008 |
2EGG
|
49.4% |
Bacillus anthracis |
Amino acid biosynthesis |
Aromatic amino acid family |
|
|
|
IDP04660
(show subtarget assignments)
|
1 |
expressed |
No |
GBAA0286 |
47777799 |
|
sensor histidine kinase, putative [Bacil... |
314 |
Phase 4: April 2009 |
2C2A
|
24.2% |
Bacillus anthracis |
Regulatory functions |
Protein interactions |
|
|
|
IDP01719
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
GBAA5560 |
47530880 |
|
ribose-5-phosphate isomerase B [Bacillus... |
147 |
Phase 3: June 2008 |
3HE8
|
55.1% |
Bacillus anthracis |
Energy metabolism |
Sugars |
|
|
|
IDP02762
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA2482 |
47527772 |
|
ABC transporter ATP-binding protein [Bac... |
256 |
Phase 3: June 2008 |
1F3O
|
40.6% |
Bacillus anthracis |
Transport and binding proteins |
Unknown substrate |
|
|
|
IDP02432
(show subtarget assignments)
|
1 |
soluble |
No |
GBAA3687 |
47528971 |
|
acetyl-CoA acetyltransferase [Bacillus a... |
363 |
Phase 3: June 2008 |
4DD5
|
39.6% |
Bacillus anthracis |
Fatty acid and phospholipid metabolism |
Other |
|
|
|
IDP02781
(show subtarget assignments)
|
1 |
in_pdb
3K28 |
No |
GBAA4693 |
47529992 |
hemL-2 |
glutamate-1-semialdehyde aminotransferas... |
429 |
Phase 3: June 2008 |
3K28
|
100% |
Bacillus anthracis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Heme, porphyrin, and cobalamin |
|
|
|
IDP04661
(show subtarget assignments)
|
1 |
expressed |
No |
GBAA0572 |
47777831 |
|
sensor histidine kinase [Bacillus anthra... |
416 |
Phase 4: April 2009 |
2C2A
|
16.6% |
Bacillus anthracis |
Regulatory functions |
Protein interactions |
|
|
|
IDP04675
(show subtarget assignments)
|
1 |
soluble |
No |
GBAA2291 |
47527591 |
|
sensor histidine kinase [Bacillus anthra... |
377 |
Phase 4: April 2009 |
3A0R
|
26.5% |
Bacillus anthracis |
Regulatory functions |
Protein interactions |
|
|
|
IDP02748
(show subtarget assignments)
|
1 |
expressed |
No |
GBAA4408 |
47529702 |
accC |
acetyl-CoA carboxylase biotin carboxylas... |
450 |
Phase 3: June 2008 |
2VPQ
|
66.4% |
Bacillus anthracis |
Fatty acid and phospholipid metabolism |
Biosynthesis |
|
|
|
IDP02237
(show subtarget assignments)
|
1 |
in_pdb
3T4X |
No |
GBAA3440 |
47528725 |
|
short chain dehydrogenase/reductase fami... |
264 |
Phase 3: June 2008 |
3T4X
|
100% |
Bacillus anthracis |
Unknown function |
Enzymes of unknown specificity |
|
|
|
IDP02750
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA5389 |
47530699 |
|
transferase hexapeptide domain-containin... |
170 |
Phase 3: June 2008 |
1KHR
|
28.8% |
Bacillus anthracis |
Central intermediary metabolism |
Other |
|
|
|
IDP02239
(show subtarget assignments)
|
1 |
expressed |
No |
GBAA0299 |
47525562 |
purD |
phosphoribosylamine--glycine ligase [Bac... |
423 |
Phase 3: June 2008 |
2YRW
|
64.5% |
Bacillus anthracis |
Purines, pyrimidines, nucleosides, and nucleotides |
Purine ribonucleotide biosynthesis |
|
|
|
IDP01711
(show subtarget assignments)
|
1 |
expressed |
No |
GBAA5380 |
47530690 |
clpP |
ATP-dependent Clp protease proteolytic s... |
193 |
Phase 3: June 2008 |
3TT7
|
89.1% |
Bacillus anthracis |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP02746
(show subtarget assignments)
|
0 |
work_stopped |
No |
GBAA0157 |
47525415 |
glmM |
phosphoglucosamine mutase [Bacillus anth... |
448 |
Phase 3: June 2008 |
3PDK
|
100% |
Bacillus anthracis |
Cell envelope |
N/A |
|
|
|
IDP02742
(show subtarget assignments)
|
1 |
expressed |
No |
GBAA2122 |
47527416 |
|
hypothetical protein GBAA2122 [Bacillus ... |
296 |
Phase 3: June 2008 |
2R44
|
42.8% |
Bacillus anthracis |
Hypothetical proteins |
Conserved |
|
|
|
IDP02425
(show subtarget assignments)
|
1 |
soluble |
No |
GBAA2775 |
47528067 |
acoB |
TPP-dependent acetoin dehydrogenase E1 b... |
344 |
Phase 3: June 2008 |
1W85
|
43.9% |
Bacillus anthracis |
Energy metabolism |
Fermentation |
|
|
|
IDP02743
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA4383 |
47529678 |
bfmbAb |
3-methyl-2-oxobutanoate dehydrogenase, b... |
327 |
Phase 3: June 2008 |
1UM9
|
52.9% |
Bacillus anthracis |
Energy metabolism |
Amino acids and amines |
|
|
|
IDP01712
(show subtarget assignments)
|
1 |
in_pdb
3EFE |
No |
GBAA2657 |
47551781 |
|
thiJ/pfpI family protein [Bacillus anthr... |
210 |
Phase 3: June 2008 |
3EFE
|
100% |
Bacillus anthracis |
N/A |
N/A |
|
|
|
IDP02036
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA1500 |
47526774 |
|
M23/37 family peptidase [Bacillus anthra... |
204 |
Phase 3: June 2008 |
3SLU
|
23.5% |
Bacillus anthracis |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP02745
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA4384 |
47529679 |
bfmbAa |
3-methyl-2-oxobutanoate dehydrogenase, a... |
333 |
Phase 3: June 2008 |
1UM9
|
41.7% |
Bacillus anthracis |
Energy metabolism |
Amino acids and amines |
|
|
|
IDP02736
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA4352 |
47778283 |
argD |
acetylornithine aminotransferase [Bacill... |
386 |
Phase 3: June 2008 |
2E54
|
44% |
Bacillus anthracis |
Amino acid biosynthesis |
Glutamate family |
|
|
|
IDP02735
(show subtarget assignments)
|
1 |
purified |
No |
GBAA4334 |
47529631 |
ribH |
riboflavin synthase subunit beta [Bacill... |
153 |
Phase 3: June 2008 |
1VSW
|
100% |
Bacillus anthracis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Riboflavin, FMN, and FAD |
|
|
|
IDP02737
(show subtarget assignments)
|
1 |
expressed |
No |
GBAA1974 |
47527269 |
|
putative lipoprotein [Bacillus anthracis... |
415 |
Phase 3: June 2008 |
|
|
Bacillus anthracis |
Cell envelope |
Other |
|
|
|
IDP02005
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA0543 |
47525816 |
|
penicillin-binding domain-containing pro... |
258 |
Phase 3: June 2008 |
2OQO
|
36% |
Bacillus anthracis |
Unknown function |
General |
|
|
|
IDP02740
(show subtarget assignments)
|
1 |
expressed |
No |
GBAA1950 |
47527245 |
|
D-alanyl-D-alanine carboxypeptidase fami... |
285 |
Phase 3: June 2008 |
3HUM
|
28.7% |
Bacillus anthracis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP02412
(show subtarget assignments)
|
1 |
soluble |
No |
GBAA4760 |
47530059 |
etfB |
electron transfer flavoprotein, beta sub... |
257 |
Phase 3: June 2008 |
1EFP
|
38.2% |
Bacillus anthracis |
Energy metabolism |
Electron transport |
|
|
|
IDP02741
(show subtarget assignments)
|
1 |
purified |
No |
GBAA1900 |
47527194 |
|
BNR repeat-containing protein [Bacillus ... |
323 |
Phase 3: June 2008 |
|
|
Bacillus anthracis |
Unknown function |
General |
|
|
|
IDP02753
(show subtarget assignments)
|
1 |
expressed |
No |
GBAA4662 |
47529960 |
nadB |
L-aspartate oxidase [Bacillus anthracis ... |
509 |
Phase 3: June 2008 |
1CHU
|
37.5% |
Bacillus anthracis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Pyridine nucleotides |
|
|
|
IDP01710
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
GBAA0371 |
47525642 |
|
glycosyl hydrolase family protein [Bacil... |
554 |
Phase 3: June 2008 |
2ZE0
|
67% |
Bacillus anthracis |
Energy metabolism |
Sugars |
|
|
|
IDP02734
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA1779 |
47527069 |
|
thioredoxin family protein [Bacillus ant... |
184 |
Phase 3: June 2008 |
1ST9
|
27.7% |
Bacillus anthracis |
Energy metabolism |
Electron transport |
|
|
|
IDP02725
(show subtarget assignments)
|
1 |
crystallized |
No |
GBAA4341 |
47529638 |
bioA |
adenosylmethionine--8-amino-7-oxononanoa... |
462 |
Phase 3: June 2008 |
3DOD
|
57.1% |
Bacillus anthracis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Biotin |
|
|
|
IDP02406
(show subtarget assignments)
|
1 |
crystallized |
No |
GBAA2768 |
47528059 |
|
thioredoxin reductase, putative [Bacillu... |
301 |
Phase 3: June 2008 |
3FBS
|
32.1% |
Bacillus anthracis |
Energy metabolism |
Electron transport |
|
|
|
IDP02404
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA2730 |
47528021 |
|
neutral protease [Bacillus anthracis str... |
567 |
Phase 3: June 2008 |
1FJ3
|
25.6% |
Bacillus anthracis |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP02726
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA4229 |
47529522 |
|
maltosaccharide ABC transporter, maltosa... |
419 |
Phase 3: June 2008 |
2ZYK
|
41.5% |
Bacillus anthracis |
Transport and binding proteins |
Carbohydrates, organic alcohols, and acids |
|
|
|
IDP02407
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA3988 |
47529279 |
acpP |
acyl carrier protein [Bacillus anthracis... |
77 |
Phase 3: June 2008 |
2X2B
|
81.8% |
Bacillus anthracis |
Fatty acid and phospholipid metabolism |
Biosynthesis |
|
|
|
IDP02724
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
GBAA1330 |
47526596 |
fabG |
acetoacetyl-CoA reductase [Bacillus anth... |
247 |
Phase 3: June 2008 |
2UVD
|
46.6% |
Bacillus anthracis |
Fatty acid and phospholipid metabolism |
Biosynthesis |
|
|
|
IDP02727
(show subtarget assignments)
|
1 |
crystallized |
No |
GBAA4249 |
47778264 |
|
3-hydroxybutyrate dehydrogenase [Bacillu... |
258 |
Phase 3: June 2008 |
3V2H
|
42.6% |
Bacillus anthracis |
Unknown function |
Enzymes of unknown specificity |
|
|
|
IDP02427
(show subtarget assignments)
|
1 |
purified |
No |
GBAA3553 |
47528837 |
pepF-2 |
oligoendopeptidase F [Bacillus anthracis... |
595 |
Phase 3: June 2008 |
2QR4
|
37.6% |
Bacillus anthracis |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP02722
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA4026 |
47529319 |
carA |
carbamoyl phosphate synthase small subun... |
365 |
Phase 3: June 2008 |
1BXR
|
46.3% |
Bacillus anthracis |
Purines, pyrimidines, nucleosides, and nucleotides |
Pyrimidine ribonucleotide biosynthesis |
|
|
|
IDP02729
(show subtarget assignments)
|
1 |
in_pdb
3SS6 |
Yes |
GBAA4240 |
47529533 |
|
acetyl-CoA acetyltransferase [Bacillus a... |
391 |
Phase 3: June 2008 |
3SS6
|
99.7% |
Bacillus anthracis |
Fatty acid and phospholipid metabolism |
Other |
|
|
|
IDP01702
(show subtarget assignments)
|
1 |
soluble |
No |
GBAA0261 |
47525520 |
gcP |
O-sialoglycoprotein endopeptidase [Bacil... |
338 |
Phase 3: June 2008 |
2IVN
|
35.2% |
Bacillus anthracis |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP01934
(show subtarget assignments)
|
1 |
soluble |
No |
GBAA0385 |
47525656 |
|
chitinase B [Bacillus anthracis str. 'Am... |
674 |
Phase 3: June 2008 |
1ITX
|
37.4% |
Bacillus anthracis |
Energy metabolism |
Biosynthesis and degradation of polysaccharides |
|
|
|
IDP02395
(show subtarget assignments)
|
1 |
expressed |
No |
GBAA3321 |
161611191 |
serC |
phosphoserine aminotransferase [Bacillus... |
324 |
Phase 3: June 2008 |
1W23
|
50% |
Bacillus anthracis |
Amino acid biosynthesis |
Serine family |
|
|
|
IDP02716
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA0325 |
47525592 |
gabT |
4-aminobutyrate aminotransferase [Bacill... |
454 |
Phase 3: June 2008 |
1SF2
|
45.2% |
Bacillus anthracis |
Central intermediary metabolism |
Other |
|
|
|
IDP02226
(show subtarget assignments)
|
1 |
crystallized |
No |
GBAA0164 |
47525422 |
yqjI |
6-phosphogluconate dehydrogenase [Bacill... |
469 |
Phase 3: June 2008 |
2W8Z
|
72.3% |
Bacillus anthracis |
Energy metabolism |
Pentose phosphate pathway |
|
|
|
IDP02717
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA3854 |
47529142 |
chi36 |
extracellular exochitinase Chi36 [Bacill... |
360 |
Phase 3: June 2008 |
3N11
|
88.6% |
Bacillus anthracis |
Energy metabolism |
Biosynthesis and degradation of polysaccharides |
|
|
|
IDP02718
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA3833 |
47529118 |
glnA |
glutamine synthetase, type I [Bacillus a... |
444 |
Phase 3: June 2008 |
3QAJ
|
86.7% |
Bacillus anthracis |
Amino acid biosynthesis |
Glutamate family |
|
|
|
IDP02040
(show subtarget assignments)
|
1 |
expressed |
No |
GBAA4637 |
47529935 |
relA |
GTP pyrophosphokinase [Bacillus anthraci... |
727 |
Phase 3: June 2008 |
1VJ7
|
31.2% |
Bacillus anthracis |
Cellular processes: Adaptations to atypical conditions |
N/A |
|
|
|
IDP02703
(show subtarget assignments)
|
1 |
crystallized |
No |
GBAA3432 |
47528718 |
tkt-1 |
transketolase [Bacillus anthracis str. '... |
674 |
Phase 3: June 2008 |
3HYL
|
58.1% |
Bacillus anthracis |
Energy metabolism |
Pentose phosphate pathway |
|
|
|
IDP02709
(show subtarget assignments)
|
1 |
purified |
No |
GBAA3964 |
47529254 |
tsf |
elongation factor Ts [Bacillus anthracis... |
295 |
Phase 3: June 2008 |
1EFU
|
47.1% |
Bacillus anthracis |
Protein synthesis |
Translation factors |
|
|
|
IDP01922
(show subtarget assignments)
|
1 |
expressed |
No |
GBAA1441 |
47526716 |
sat |
sulfate adenylyltransferase [Bacillus an... |
378 |
Phase 3: June 2008 |
1V47
|
39.4% |
Bacillus anthracis |
Central intermediary metabolism |
Sulfur metabolism |
|
|
|
IDP02533
(show subtarget assignments)
|
1 |
expressed |
No |
GBAA4184 |
47529480 |
pdhA |
pyruvate dehydrogenase complex E1 compon... |
371 |
Phase 3: June 2008 |
3DUF
|
80.9% |
Bacillus anthracis |
Energy metabolism |
Pyruvate dehydrogenase |
|
|
|
IDP02711
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA5551 |
47530871 |
atpF |
F0F1 ATP synthase subunit B [Bacillus an... |
168 |
Phase 3: June 2008 |
|
|
Bacillus anthracis |
Energy metabolism |
ATP-proton motive force interconversion |
|
|
|
IDP01917
(show subtarget assignments)
|
1 |
soluble |
No |
GBAA1429 |
47526701 |
hisA |
1-(5-phosphoribosyl)-5-[(5-phosphoribosy... |
239 |
Phase 3: June 2008 |
1VZW
|
36.5% |
Bacillus anthracis |
Amino acid biosynthesis |
Histidine family |
|
|
|
IDP02392
(show subtarget assignments)
|
1 |
soluble |
No |
GBAA2294 |
47527593 |
|
hypothetical protein GBAA2294 [Bacillus ... |
436 |
Phase 3: June 2008 |
3I4J
|
38.3% |
Bacillus anthracis |
Unknown function |
Enzymes of unknown specificity |
|
|
|
IDP02712
(show subtarget assignments)
|
1 |
in_pdb
3IFE |
No |
GBAA3872 |
47529163 |
pepT-1 |
peptidase T [Bacillus anthracis str. 'Am... |
410 |
Phase 3: June 2008 |
3IFE
|
100% |
Bacillus anthracis |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP01704
(show subtarget assignments)
|
1 |
expressed |
No |
GBAA5215 |
47530521 |
|
aminotransferase, class V [Bacillus anth... |
406 |
Phase 3: June 2008 |
1T3I
|
51% |
Bacillus anthracis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Other |
|
|
|
IDP02396
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
GBAA3604 |
47528890 |
argH-1 |
argininosuccinate lyase [Bacillus anthra... |
502 |
Phase 3: June 2008 |
2E9F
|
27.5% |
Bacillus anthracis |
Amino acid biosynthesis |
Glutamate family |
|
|
|
IDP02720
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA3950 |
47529240 |
infB |
translation initiation factor IF-2 [Baci... |
686 |
Phase 3: June 2008 |
1ZO1
|
42% |
Bacillus anthracis |
Protein synthesis |
Translation factors |
|
|
|
IDP01913
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA1426 |
47526698 |
hisD |
histidinol dehydrogenase [Bacillus anthr... |
429 |
Phase 3: June 2008 |
1K75
|
39.2% |
Bacillus anthracis |
Amino acid biosynthesis |
Histidine family |
|
|
|
IDP01906
(show subtarget assignments)
|
1 |
soluble |
No |
GBAA0294 |
47525557 |
purL |
phosphoribosylformylglycinamidine syntha... |
739 |
Phase 3: June 2008 |
3AC6
|
46.5% |
Bacillus anthracis |
Purines, pyrimidines, nucleosides, and nucleotides |
Purine ribonucleotide biosynthesis |
|
|
|
IDP01892
(show subtarget assignments)
|
1 |
in_pdb
3HVU
3KB8
3H83 |
No |
GBAA0063 |
47525317 |
hpt-1 |
hypoxanthine-guanine phosphoribosyltrans... |
180 |
Phase 3: June 2008 |
3H83
|
100% |
Bacillus anthracis |
Purines, pyrimidines, nucleosides, and nucleotides |
Salvage of nucleosides and nucleotides |
|
|
|
IDP02386
(show subtarget assignments)
|
1 |
selected |
No |
GBAA3086 |
47528378 |
|
Signal peptidase I [Bacillus anthracis s... |
173 |
Phase 3: June 2008 |
1B12
|
10.4% |
Bacillus anthracis |
Protein fate |
Protein and peptide secretion and trafficking |
|
|
|
IDP01885
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA5639 |
47530965 |
|
D-alanyl-D-alanine carboxypeptidase, put... |
423 |
Phase 3: June 2008 |
1XP4
|
32.2% |
Bacillus anthracis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP00003
(show subtarget assignments)
|
1 |
expressed |
No |
GBAA_pXO1_0158 |
47566470 |
gerXC |
spore germination protein xc, (pxo1-112)... |
317 |
Phase 1: October 2007 |
|
|
Bacillus anthracis |
|
|
|
|
|
IDP01887
(show subtarget assignments)
|
1 |
expressed |
No |
GBAA5729 |
47531065 |
spo0J |
stage 0 sporulation protein J [Bacillus ... |
256 |
Phase 3: June 2008 |
1VZ0
|
36.3% |
Bacillus anthracis |
Cellular processes |
Sporulation and germination |
|
|
|
IDP01888
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA5730 |
47531066 |
soJ |
sporulation initiation inhibitor protein... |
253 |
Phase 3: June 2008 |
1WCV
|
48.6% |
Bacillus anthracis |
Regulatory functions |
Other |
|
|
|
IDP02399
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA2559 |
47527848 |
|
D-alanyl-D-alanine carboxypeptidase fami... |
338 |
Phase 3: June 2008 |
1XP4
|
26.3% |
Bacillus anthracis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP01877
(show subtarget assignments)
|
1 |
crystallized |
No |
GBAA0080 |
47525336 |
|
negative regulator of genetic competence... |
811 |
Phase 3: June 2008 |
3PXI
|
80.1% |
Bacillus anthracis |
Cellular processes |
DNA transformation |
|
|
|
IDP01876
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA0095 |
47525349 |
secE |
preprotein translocase subunit SecE [Bac... |
59 |
Phase 3: June 2008 |
3DIN
|
33.9% |
Bacillus anthracis |
Protein fate |
Protein and peptide secretion and trafficking |
|
|
|
IDP01915
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA1421 |
47777930 |
leuB |
3-isopropylmalate dehydrogenase [Bacillu... |
354 |
Phase 3: June 2008 |
3U1H
|
60.3% |
Bacillus anthracis |
Amino acid biosynthesis |
Pyruvate family |
|
|
|
IDP01874
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA0062 |
47525316 |
|
hypothetical protein GBAA0062 [Bacillus ... |
476 |
Phase 3: June 2008 |
3A2K
|
46.6% |
Bacillus anthracis |
Hypothetical proteins |
Conserved |
|
|
|
IDP01875
(show subtarget assignments)
|
1 |
expressed |
No |
GBAA0069 |
47525323 |
pabA-1 |
para-aminobenzoate/anthranilate synthase... |
195 |
Phase 3: June 2008 |
1QDL
|
45.6% |
Bacillus anthracis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Folic acid |
|
|
|
IDP02244
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA1818 |
47777969 |
|
N-acetylmuramoyl-L-alanine amidase [Baci... |
459 |
Phase 3: June 2008 |
3PYW
|
12.6% |
Bacillus anthracis |
Cell envelope |
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
|
|
|
IDP01881
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA0009 |
47525265 |
dacA |
D-alanyl-D-alanine carboxypeptidase [Bac... |
435 |
Phase 3: June 2008 |
1XP4
|
32.4% |
Bacillus anthracis |
Cell envelope |
Biosynthesis and degradation of murein sacculus and peptidoglycan |
|
|
|
IDP02428
(show subtarget assignments)
|
1 |
expressed |
No |
GBAA3580 |
47528865 |
|
O-acetyltransferase, putative [Bacillus ... |
188 |
Phase 3: June 2008 |
3VBI
|
99.5% |
Bacillus anthracis |
Cell envelope |
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
|
|
|
IDP02721
(show subtarget assignments)
|
1 |
soluble |
No |
GBAA4007 |
47529300 |
coaBC |
bifunctional phosphopantothenoylcysteine... |
401 |
Phase 3: June 2008 |
1U7U
|
23.2% |
Bacillus anthracis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Pantothenate and coenzyme A |
|
|
|
IDP02758
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA_pXO2_0073 |
47566739 |
|
signal peptidase i, (pxo2-59) [Bacillus ... |
183 |
Phase 3: June 2008 |
1B12
|
8.7% |
Bacillus anthracis |
N/A |
N/A |
|
|
|
IDP04659
(show subtarget assignments)
|
1 |
soluble |
No |
GBAA0272 |
47525531 |
|
sensor histidine kinase [Bacillus anthra... |
501 |
Phase 4: April 2009 |
2C2A
|
15.2% |
Bacillus anthracis |
Regulatory functions |
Protein interactions |
|
|
|
IDP01863
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA5548 |
47778410 |
atpG |
F0F1 ATP synthase subunit gamma [Bacillu... |
286 |
Phase 3: June 2008 |
2QE7
|
58.7% |
Bacillus anthracis |
Energy metabolism |
ATP-proton motive force interconversion |
|
|
|
IDP01862
(show subtarget assignments)
|
1 |
soluble |
No |
GBAA5510 |
47530828 |
tagH |
teichoic acids export protein ATP-bindin... |
549 |
Phase 3: June 2008 |
1F3O
|
12.4% |
Bacillus anthracis |
Transport and binding proteins |
Other |
|
|
|
IDP01864
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
GBAA5568 |
47778411 |
|
sua5/yciO/yrdC/ywlC family protein [Baci... |
346 |
Phase 3: June 2008 |
2EQA
|
43.4% |
Bacillus anthracis |
Unknown function |
General |
|
|
|
IDP02375
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
GBAA4701 |
47530000 |
engB |
GTPase EngB [Bacillus anthracis str. 'Am... |
198 |
Phase 3: June 2008 |
1SUL
|
72.2% |
Bacillus anthracis |
Unknown function |
General |
|
|
|
IDP01865
(show subtarget assignments)
|
1 |
in_pdb
3Q94 |
No |
GBAA5580 |
47530901 |
fba-2 |
fructose-bisphosphate aldolase [Bacillus... |
285 |
Phase 3: June 2008 |
3Q94
|
100% |
Bacillus anthracis |
Energy metabolism |
Glycolysis/gluconeogenesis |
|
|
|
IDP02683
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA2008 |
47527306 |
|
ribosome-associated GTPase [Bacillus ant... |
364 |
Phase 3: June 2008 |
1T9H
|
25.8% |
Bacillus anthracis |
Hypothetical proteins |
Conserved |
|
|
|
IDP02374
(show subtarget assignments)
|
1 |
purified |
No |
GBAA3116 |
47528407 |
ppsA |
phosphoenolpyruvate synthase [Bacillus a... |
868 |
Phase 3: June 2008 |
2OLS
|
15.7% |
Bacillus anthracis |
Energy metabolism |
Glycolysis/gluconeogenesis |
|
|
|
IDP01852
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA5449 |
47530763 |
celA-3 |
PTS system, cellobiose-specific IIB comp... |
100 |
Phase 3: June 2008 |
1H9C
|
41% |
Bacillus anthracis |
Transport and binding proteins |
Carbohydrates, organic alcohols, and acids |
|
|
|
IDP02377
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
GBAA1442 |
47526717 |
cysC |
adenylylsulfate kinase [Bacillus anthrac... |
197 |
Phase 3: June 2008 |
3UIE
|
51.3% |
Bacillus anthracis |
Central intermediary metabolism |
Sulfur metabolism |
|
|
|
IDP01851
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA5427 |
47778402 |
|
endopeptidase lytE, putative [Bacillus a... |
436 |
Phase 3: June 2008 |
3H41
|
9.9% |
Bacillus anthracis |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP01870
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA5710 |
47531047 |
|
serine protease [Bacillus anthracis str.... |
391 |
Phase 3: June 2008 |
3GCN
|
31.2% |
Bacillus anthracis |
Protein fate |
Degradation of proteins, peptides, and glycopeptides |
|
|
|
IDP01847
(show subtarget assignments)
|
1 |
soluble |
No |
GBAA5416 |
47530729 |
ftsE |
cell division ABC transporter, ATP-bindi... |
214 |
Phase 3: June 2008 |
3DHW
|
41.1% |
Bacillus anthracis |
Cellular processes |
Cell division |
|
|
|
IDP02370
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
GBAA1958 |
47527254 |
fabG |
3-ketoacyl-(acyl-carrier-protein) reduct... |
242 |
Phase 3: June 2008 |
3OEC
|
40.9% |
Bacillus anthracis |
Unknown function |
Enzymes of unknown specificity |
|
|
|
IDP02674
(show subtarget assignments)
|
1 |
purified |
No |
GBAA1562 |
47777948 |
panB |
3-methyl-2-oxobutanoate hydroxymethyltra... |
279 |
Phase 3: June 2008 |
1M3U
|
43% |
Bacillus anthracis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Pantothenate and coenzyme A |
|
|
|
IDP01844
(show subtarget assignments)
|
1 |
soluble |
No |
GBAA1428 |
47526700 |
hisH |
imidazole glycerol phosphate synthase su... |
209 |
Phase 3: June 2008 |
1GPW
|
35.9% |
Bacillus anthracis |
Amino acid biosynthesis |
Histidine family |
|
|
|
IDP01868
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA5583 |
47530904 |
ctrA |
CTP synthetase [Bacillus anthracis str. ... |
535 |
Phase 3: June 2008 |
1S1M
|
56.1% |
Bacillus anthracis |
Purines, pyrimidines, nucleosides, and nucleotides |
Pyrimidine ribonucleotide biosynthesis |
|
|
|
IDP02676
(show subtarget assignments)
|
1 |
crystallized |
No |
GBAA1539 |
47526813 |
hisC-1 |
histidinol-phosphate aminotransferase [B... |
370 |
Phase 3: June 2008 |
3FFH
|
46.2% |
Bacillus anthracis |
Amino acid biosynthesis |
Histidine family |
|
|
|
IDP02670
(show subtarget assignments)
|
1 |
cloned |
No |
GBAA4353 |
47529649 |
argB |
acetylglutamate kinase [Bacillus anthrac... |
255 |
Phase 3: June 2008 |
2BTY
|
43.1% |
Bacillus anthracis |
Amino acid biosynthesis |
Glutamate family |
|
|
|
IDP01839
(show subtarget assignments)
|
1 |
in_crystallization_trials |
No |
GBAA1563 |
47526836 |
panC |
pantoate--beta-alanine ligase [Bacillus ... |
282 |
Phase 3: June 2008 |
2X3F
|
53.2% |
Bacillus anthracis |
Biosynthesis of cofactors, prosthetic groups, and carriers |
Pantothenate and coenzyme A |
|
|
|
IDP02652
(show subtarget assignments)
|
1 |
expressed |
No |
GBAA1422 |
47526694 |
leuC |
isopropylmalate isomerase large subunit ... |
464 |
Phase 3: June 2008 |
2B3X
|
22% |
Bacillus anthracis |
Amino acid biosynthesis |
Pyruvate family |
|
|
|
IDP01695
(show subtarget assignments)
|
1 |
expressed |
No |
GBAA0228 |
47525485 |
|
ABC transporter ATP-binding protein [Bac... |
626 |
Phase 3: June 2008 |
1YQT
|
20.9% |
Bacillus anthracis |
Transport and binding proteins |
Unknown substrate |
|
|
|
