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Targets
Filter Targets:
Selection Phase:
No Filter
Community Interest
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM10+
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
[Clostridium] difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
0
1
6
8
Keyword:
Type Keyword
Stage:
No Filter
cloned
crystallized
crystal_structure
diffraction
expressed
in_crystallization_trials
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Screening
No Filter
Yes
No
Remove Filters
Download data as tab-separated value (TSV) file
(which can be used as a input for Microsoft Office Excel and Open Office Calc)
Jump to Target:
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IDP#
NCBI GI
LOCUS TAG
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Page 8 of 60, showing 100 records out of 5973 total, starting on record 701
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CSGID ID
Priority
stage
Screening
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP90412
(
show subtarget assignments
)
8
expressed
No
CT_657
3329107
hypothetical protein [Chlamydia trachoma...
105
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90413
(
show subtarget assignments
)
8
cloned
No
CT_622
3329069
CHLPN 76kDa Homolog [Chlamydia trachomat...
647
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90116
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_025
68449099
kelch-like protein [Monkeypox virus]
107
similar to MPXV-ZAI96-D18L, part of VACV-COP-C2L
Community Requests
3HVE
21.5%
Monkeypox virus
IDP90007
(
show subtarget assignments
)
8
cloned
No
Z4378
12517596
qseC
quorum sensing Escherichia coli regulato...
449
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3JZ3
47%
Escherichia coli
IDP90419
(
show subtarget assignments
)
8
cloned
No
CT_446
3328878
euo
CHLPS Euo Protein [Chlamydia trachomatis...
183
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90121
(
show subtarget assignments
)
8
purified
No
MPXV_ZAI1979_005_031
68449105
ankyrin-like protein [Monkeypox virus]
284
similar to VACV-COP-K1L, MPXV-ZAI96-C1L
Community Requests
3KEA
94.7%
Monkeypox virus
IDP90086
(
show subtarget assignments
)
8
expressed
No
ZZZ_0002
492
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90222
(
show subtarget assignments
)
1
in_pdb
3H2Y
No
BAS4233
49187229
YqeH
GTP-binding protein YqeH, possibly invol...
368
YqeH is an essential GTP-binding protein. Depletion of YqeH induces an excess in...
January 2009
3H2Y
100%
Bacillus anthracis
IDP90641
(
show subtarget assignments
)
8
in_crystallization_trials
No
Cj0099
15791487
birA
biotin--protein ligase [Campylobacter je...
217
Predicted Essential
Community Requests
2EAY
27.2%
Campylobacter jejuni
IDP90249
(
show subtarget assignments
)
8
soluble
No
VC2645
15642640
acetylornithine deacetylase [Vibrio chol...
378
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
2F7V
26.8%
Vibrio cholerae
IDP90504
(
show subtarget assignments
)
8
purified
No
VC0006
15640038
rnpA
ribonuclease P [Vibrio cholerae O1 biova...
118
Predicted Essential
Community Requests
2LJP
54.2%
Vibrio cholerae
IDP90420
(
show subtarget assignments
)
8
cloned
No
CT_465
3328899
hypothetical protein [Chlamydia trachoma...
213
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90118
(
show subtarget assignments
)
8
soluble
No
MPXV_ZAI1979_005_028
68449102
alpha-amanitin target protein [Monkeypox...
177
similar to VACV-COP-N2L, MPXV-ZAI96-P2L
Community Requests
Monkeypox virus
IDP90702
(
show subtarget assignments
)
8
expressed
No
Cj0134
15791522
thrB
homoserine kinase [Campylobacter jejuni ...
292
Predicted Essential
Community Requests
3HUL
30.2%
Campylobacter jejuni
IDP90422
(
show subtarget assignments
)
8
cloned
No
CT_471
3328905
hypothetical protein [Chlamydia trachoma...
200
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90776
(
show subtarget assignments
)
8
purified
No
STM2365
16765692
folC
bifunctional folylpolyglutamate synthase...
422
Predicted Essential
Community Requests
1W78
86.7%
Salmonella enterica
IDP90421
(
show subtarget assignments
)
8
expressed
No
CT_433
3328864
hypothetical protein [Chlamydia trachoma...
223
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90619
(
show subtarget assignments
)
8
soluble
No
Cj1701c
15793004
rpsC
30S ribosomal protein S3 [Campylobacter ...
233
Predicted Essential
Community Requests
1VS5
56.7%
Campylobacter jejuni
IDP90005
(
show subtarget assignments
)
8
soluble
No
Z4377
12517595
qseB
quorum sensing Escherichia coli regulato...
219
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3Q9S
41.1%
Escherichia coli
IDP90424
(
show subtarget assignments
)
8
cloned
No
CT_546
3328985
predicted OMP [Chlamydia trachomatis D/U...
289
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90704
(
show subtarget assignments
)
8
in_crystallization_trials
No
Cj0269c
15791640
ilvE
branched-chain amino acid aminotransfera...
304
Predicted Essential
Community Requests
3U0G
55.6%
Campylobacter jejuni
IDP90117
(
show subtarget assignments
)
8
in_crystallization_trials
No
MPXV_ZAI1979_005_027
68449101
virokine protein [Monkeypox virus]
117
similar to VACV-COP-N1L, MPXV-ZAI96-P1L
Community Requests
2I39
89.7%
Monkeypox virus
IDP00183
(
show subtarget assignments
)
1
cloned
No
YPO0613
16120939
-
putative permease protein
293
Virulence
Phase 1: October 2007
2R6G
22.5%
Yersinia pestis
IDP90425
(
show subtarget assignments
)
8
expressed
No
CT_547
3328986
hypothetical protein [Chlamydia trachoma...
318
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3QKY
11.9%
Chlamydia trachomatis
IDP90584
(
show subtarget assignments
)
8
purified
No
VC0095
15640127
chorismate--pyruvate lyase [Vibrio chole...
183
Predicted Essential
Community Requests
1FW9
28.4%
Vibrio cholerae
IDP01109
(
show subtarget assignments
)
1
soluble
No
GBAA_pXO1_0148
47566460
hypothetical protein GBAA_pXO1_0148
150
Virulence Associated Factor
Phase 2: March 2008
3PMD
100%
Bacillus anthracis
IDP90705
(
show subtarget assignments
)
8
soluble
No
Cj1400c
15792718
fabI
enoyl-(acyl carrier protein) reductase [...
274
Predicted Essential
Community Requests
2PD3
67.2%
Campylobacter jejuni
IDP90003
(
show subtarget assignments
)
8
crystallized
No
FTT1103
56708183
conserved hypothetical lipoprotein
365
(Community Request)
Community Requests
3GYK
12.3%
Francisella tularensis
IDP01101
(
show subtarget assignments
)
1
expressed
No
GBAA_pXO1_0119
47566439
hypothetical protein GBAA_pXO1_0119
82
Virulence Associated Factor
Phase 2: March 2008
3SIK
52.4%
Bacillus anthracis
IDP90427
(
show subtarget assignments
)
8
cloned
No
CT_847
3329319
hypothetical protein [Chlamydia trachoma...
172
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90707
(
show subtarget assignments
)
8
purified
No
Cj0233c
15791605
pyrE
orotate phosphoribosyltransferase [Campy...
202
Predicted Essential
Community Requests
2YZK
22.3%
Campylobacter jejuni
IDP90821
(
show subtarget assignments
)
8
soluble
No
VC0120
15640152
hemC
porphobilinogen deaminase [Vibrio choler...
317
Predicted Essential
Community Requests
1AH5
73.5%
Vibrio cholerae
IDP90816
(
show subtarget assignments
)
8
soluble
No
YPO2878
16123070
hisS
histidyl-tRNA synthetase [Yersinia pesti...
424
Predicted Essential
Community Requests
1KMM
82.1%
Yersinia pestis
IDP90937
(
show subtarget assignments
)
8
cloned
No
YPO0110
16120456
priA
primosome assembly protein PriA
732
Predicted Essential
Community Requests
2EYQ
9.4%
Yersinia pestis
IDP90120
(
show subtarget assignments
)
8
cloned
No
MPXV_ZAI1979_005_030
68449104
unknown [Monkeypox virus]
220
similar to VACV-COP-M2L, MPXV-ZAI96-O2L
Community Requests
Monkeypox virus
IDP90225
(
show subtarget assignments
)
8
in_pdb
3K29
No
CT670
3329121
Hypothetical
168
Chlamydia type III secretion associated protein CT670
Community Requests
3K29
100%
Chlamydia trachomatis
IDP90081
(
show subtarget assignments
)
8
cloned
No
ABD79034.1
89892477
M2
matrix protein 2 [Influenza A virus (A/U...
96
Influenza matrix protein 2 (M2) is a validated therapeutic target whose on-marke...
Community Requests
2L0J
42.7%
Influenza A
IDP90085
(
show subtarget assignments
)
8
purified
No
ZZZ_0001
158
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP90248
(
show subtarget assignments
)
8
purified
No
BAS0467
49183495
acetylornithine deacetylase [Bacillus an...
426
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3PFO
27%
Bacillus anthracis
IDP90224
(
show subtarget assignments
)
8
in_pdb
3I0U
No
CP0010
31983551
OspF
Shigella OspF effector
239
Shigella OspF effector
Community Requests
3I0U
90.8%
Shigella flexneri
IDP90223
(
show subtarget assignments
)
1
expressed
No
SA1226
15926974
Asd
Aspartate semialdehyde dehydrogenase Asd...
329
This enzyme participates in glycine, serine and threonine metabolism and lysine ...
January 2009
2YV3
43.4%
Staphylococcus aureus
IDP90429
(
show subtarget assignments
)
8
cloned
No
CT_860
3329334
hypothetical protein [Chlamydia trachoma...
493
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90432
(
show subtarget assignments
)
8
in_crystallization_trials
No
CT_865
3329339
hypothetical protein [Chlamydia trachoma...
329
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90226
(
show subtarget assignments
)
1
selected
No
VC2428
9657003
conserved hypothetical protein [Vibrio c...
246
Conserved gene clusters with virulence associated genes. Conserved Protein; Pred...
January 2009
2OEZ
74.8%
Vibrio cholerae
IDP90503
(
show subtarget assignments
)
8
purified
No
NP_230169
15642769
DNA primase [Vibrio cholerae O1 biovar e...
587
Predicted Essential
Community Requests
1DD9
30.8%
Vibrio cholerae
IDP90615
(
show subtarget assignments
)
8
in_crystallization_trials
No
VC0626
15640646
glutamate-1-semialdehyde aminotransferas...
432
Predicted Essential
Community Requests
4E77
72%
Vibrio cholerae
IDP90227
(
show subtarget assignments
)
0
work_stopped
No
BAS1428
49184445
-
Histidinol-phosphate aminotransferase (E...
370
Histidinol phosphate aminotransferase (EC 2.6.1.9) is a key enzyme on the histid...
January 2009
3FFH
46.2%
Bacillus anthracis
IDP90589
(
show subtarget assignments
)
8
soluble
No
VC0296
15640324
acetyl-CoA carboxylase [Vibrio cholerae ...
196
Predicted Essential
Community Requests
1A6X
37.2%
Vibrio cholerae
IDP90228
(
show subtarget assignments
)
1
in_pdb
3T5P
3S40
No
BAS4713
49187704
-
Transcription regulator [contains diacyl...
300
Transcription regulator [contains diacylglycerol kinase catalytic domain]; Predi...
January 2009
3S40
100%
Bacillus anthracis
IDP90242
(
show subtarget assignments
)
8
expressed
No
SA1814
15927582
succinyl-diaminopimelate desuccinylase [...
407
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3TX8
25.5%
Staphylococcus aureus
IDP01169
(
show subtarget assignments
)
1
cloned
No
GBAA_pXO1_0146
47566458
atxA
transcriptional activator atxa, (pxo1-11...
475
Virulence Associated Factor
Phase 2: March 2008
3SQN
20.4%
Bacillus anthracis
IDP90436
(
show subtarget assignments
)
8
cloned
No
CT_872
3329347
pmpH
Putative Outer Membrane Protein H [Chlam...
1016
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90247
(
show subtarget assignments
)
8
purified
No
YPO3928
115349537
argE
acetylornithine deacetylase [Yersinia pe...
389
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3PFO
26%
Yersinia pestis
IDP90643
(
show subtarget assignments
)
8
soluble
No
VC0638
15640658
dihydropteroate synthase [Vibrio cholera...
278
Predicted Essential
Community Requests
1AJ0
55.8%
Vibrio cholerae
IDP90502
(
show subtarget assignments
)
8
purified
No
Q9KPA4
22653875
RecName: Full=L-aspartate oxidase; Short...
535
Predicted Essential
Community Requests
1CHU
75.3%
Vibrio cholerae
IDP90434
(
show subtarget assignments
)
8
cloned
No
CT_870
3329345
pmpF
Putative Outer Membrane Protein F [Chlam...
1034
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90435
(
show subtarget assignments
)
8
cloned
No
CT_871
3329346
pmpG
Putative Outer Membrane Protein G [Chlam...
1013
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90617
(
show subtarget assignments
)
8
crystallized
No
YPO3927
16124057
argC
N-acetyl-gamma-glutamyl-phosphate reduct...
334
Predicted Essential
Community Requests
2G17
78.1%
Yersinia pestis
IDP90084
(
show subtarget assignments
)
8
soluble
No
ZP_01795673
145640079
hypothetical protein CGSHiII_00674 [Haem...
148
The protein we would like structure analyzed is from Haemophilus influenzae. Pri...
Community Requests
2XM6
28.4%
Haemophilus influenzae
IDP90246
(
show subtarget assignments
)
8
in_pdb
3T68
3T6M
Yes
VC2152
15642151
succinyl-diaminopimelate desuccinylase [...
377
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
3T68
70%
Vibrio cholerae
IDP90616
(
show subtarget assignments
)
8
selected
No
VC1054
15641067
DNA polymerase III subunits gamma and ta...
692
Predicted Essential
Community Requests
1JR3
34.5%
Vibrio cholerae
IDP90083
(
show subtarget assignments
)
8
cloned
No
ZP_01795671
145640077
hypothetical protein CGSHiII_00664 [Haem...
219
The protein we would like structure analyzed is from Haemophilus influenzae. Pri...
Community Requests
2XM6
35.6%
Haemophilus influenzae
IDP90082
(
show subtarget assignments
)
8
purified
No
P03493.2
85681917
RecName: Full=Matrix protein 2; AltName:...
109
Influenza matrix protein 2 (M2) is a validated therapeutic target whose on-marke...
Community Requests
2KJ1
64.2%
Influenza B
IDP90437
(
show subtarget assignments
)
8
cloned
No
CT_869
3329344
pmpE
Putative Outer Membrane Protein E [Chlam...
964
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP90586
(
show subtarget assignments
)
8
cloned
No
YPO2188
16122418
cls
cardiolipin synthetase [Yersinia pestis ...
486
Predicted Essential
Community Requests
Yersinia pestis
IDP90169
(
show subtarget assignments
)
8
expressed
No
AAM13454.1
20152993
CPXV008 CDS
CPXV008 protein
672
Potential drug target. Shikimate pathway enzyme
Community Requests
Cowpox virus
conserved hypothetical proteins
0
IDP00846
(
show subtarget assignments
)
1
cloned
No
SACOL1177
57284462
hypothetical protein SACOL1177
43
Drug Target Function
Phase 2: March 2008
Staphylococcus aureus
0
0
IDP00843
(
show subtarget assignments
)
1
cloned
No
SACOL1859
57284780
hypothetical protein SACOL1859
1016
Drug Target Function
Phase 2: March 2008
Staphylococcus aureus
0
0
IDP90217
(
show subtarget assignments
)
8
soluble
No
MYXV_gp004
9633795
m003.1L
m003.1L, m3.1
151
similar to VACV-Cop:B22R, member of Poxvirus A4/B15 family. This is a family of ...
Community Requests
2VVY
29.8%
Myxoma virus
unknown
0
IDP90218
(
show subtarget assignments
)
8
soluble
No
MYXV_gp151
9633783
m148R
m148R
675
ankyrin motif, similar to VACV-Cop:B4R
Community Requests
2J8S
6.1%
Myxoma virus
host range factor
0
IDP90219
(
show subtarget assignments
)
8
expressed
No
MYXV_gp011
9633802
m008L
m008L, m8
515
contains kelch motifs, similar to MYX-L-m006R
Community Requests
2XN4
11.5%
Myxoma virus
unknown
0
IDP90220
(
show subtarget assignments
)
8
selected
No
MYXV_gp153
9633785
m150R
m150R
494
ankyrin-like protein, myxoma nuclear factor
Community Requests
Myxoma virus
host range factor
0
IDP90221
(
show subtarget assignments
)
8
cloned
No
MYXV_gp157
9633790
m154L
m154L, gp120-like
214
NFkB inhibitor, similar to VACV-Cop:M2L
Community Requests
Myxoma virus
host defense modulator
0
IDP00810
(
show subtarget assignments
)
1
cloned
No
SACOL1870
57284791
hypothetical protein SACOL1870
188
Conserved Gene / Pathway
Phase 2: March 2008
Staphylococcus aureus
0
0
IDP90213
(
show subtarget assignments
)
8
purified
No
MYXV_gp033
9633665
m029L
m029L, m29L
115
IFN resistance, PKR inhibitor
Community Requests
2YT4
19.1%
Myxoma virus
host range factor, host defense modulator
0
IDP90212
(
show subtarget assignments
)
8
cloned
No
MYXV_gp067
9633699
m063R
m063R, m63R
215
CD47-likeĀ
Community Requests
Myxoma virus
host range factor, host defense modulator
0
IDP90210
(
show subtarget assignments
)
8
expressed
No
MYXV_gp140
9633772
m136R
m136R
179
unknown, similar to VACV-Cop:A52R
Community Requests
2VVW
20.1%
Myxoma virus
unknown, conserved protein
0
IDP90211
(
show subtarget assignments
)
8
cloned
No
MYXV_gp132
9633764
m128L
m128L
281
integrin-associated protein homolog similar to VACV-Cop:A38L. Five pass TM prote...
Community Requests
Myxoma virus
host defense modulator
0
IDP90215
(
show subtarget assignments
)
8
expressed
No
MYXV_gp009
9633800
m006L
m006L, m6
509
contains kelch motifs, similar to MYX-L-m006R
Community Requests
1X2J
13.9%
Myxoma virus
unknown
0
IDP90214
(
show subtarget assignments
)
8
expressed
No
MYXV_gp017
9633649
m013L
m013L, M013L
126
interferon inducible protein
Community Requests
Myxoma virus
unknown
0
IDP90206
(
show subtarget assignments
)
8
soluble
No
MYXV_gp149
9633781
m146R
m146R
108
virokine/NFkB inh/Str resemblence to apoptotic reg, similar to VACV-Cop:N1L
Community Requests
2I39
26.9%
Myxoma virus
host defense modulator
0
IDP90208
(
show subtarget assignments
)
8
expressed
No
MYXV_gp143
9633775
m139R
m139R
188
Intracellular TLR and IL-1 signaling inhibitor, similar to VACV-Cop:A52R
Community Requests
2VVW
32.4%
Myxoma virus
host defense modulator
0
IDP90207
(
show subtarget assignments
)
8
soluble
No
MYXV_gp152
9633784
m149R
m149R
490
ankyrin motif, similar to VACV-Cop:B4R
Community Requests
1N11
14.9%
Myxoma virus
host range factor
0
IDP90204
(
show subtarget assignments
)
8
cloned
No
AAM13452.1
20152991
CPXV006 CDS
CPXV006 protein
619
ankyrin repeat protein
Community Requests
Cowpox virus
conserved hypothetical proteins
0
IDP90205
(
show subtarget assignments
)
8
expressed
No
AAM13465.1
20153004
CPXV018 CDS
CPXV018 protein, VO18
171
similar to MPV-Z-N3R
Community Requests
Cowpox virus
host defense modulator
0
IDP90209
(
show subtarget assignments
)
8
expressed
No
MYXV_gp144
9633776
m140R
m140R
553
kelch motif, similar to VACV-Cop:A55R
Community Requests
1U6D
14.3%
Myxoma virus
unknown, conserved protein
0
IDP90203
(
show subtarget assignments
)
8
selected
No
AAM13658.1
20153197
CPXV220 CDS
CPXV220 protein
579
ankyrin-like protein
Community Requests
2FO1
10.4%
Cowpox virus
conserved hypothetical proteins
0
IDP90197
(
show subtarget assignments
)
8
soluble
No
AAM13645.1
20153184
CPXV206 CDS
CPXV206 protein
285
serine-threonine kinase
Community Requests
2KTY
32.1%
Cowpox virus
Unknown function
0
IDP90198
(
show subtarget assignments
)
8
expressed
No
AAM13648.1
20153187
CPXV209
CPXV209 protein
326
soluble secreted IL-1 binding protein
Community Requests
3O4O
28.5%
Cowpox virus
host defense modulator
0
IDP90199
(
show subtarget assignments
)
8
cloned
No
AAM13650.1
20153189
CPXV211 CDS
CPXV211 protein
574
ankyrin-like protein
Community Requests
3F6Q
5.6%
Cowpox virus
conserved hypothetical proteins
0
IDP90200
(
show subtarget assignments
)
8
purified
No
AAM13652.1
20153191
CPXV213 CDS
CPXV213 protein
800
ankyrin-like protein
Community Requests
Cowpox virus
conserved hypothetical proteins
0
IDP90216
(
show subtarget assignments
)
8
expressed
No
MYXV_gp008
9633799
m005L
m005L, m5, M-T5
483
ankyrin motif, similar to VACV-Cop:B4R. Possible apoptosis regulator.
Community Requests
1N0R
8.5%
Myxoma virus
host range factor, host defense modulator
0
IDP90196
(
show subtarget assignments
)
8
cloned
No
AAM13643.1
20153182
CPXV204 CDS
CPXV204 protein
501
kelch-like protein
Community Requests
2VPJ
14%
Cowpox virus
conserved hypothetical proteins
0
IDP90201
(
show subtarget assignments
)
8
cloned
No
AAM13653.1
20153192
CPXV215 CDS
CPXV215 Protein
557
kelch-like protein
Community Requests
2VPJ
12.2%
Cowpox virus
conserved hypothetical proteins
0
IDP90195
(
show subtarget assignments
)
8
soluble
No
AAM13642.1
20153181
CPXV203 CDS
CPXV203 protein
225
ER-localized, MHC-I inhibitor
Community Requests
Cowpox virus
host defense modulator
0
IDP90194
(
show subtarget assignments
)
8
expressed
No
AAM13639.1
20153178
CPXV200 CDS
CPXV200 protein
179
ankyrin-like protein
Community Requests
Cowpox virus
conserved hypothetical proteins
0
IDP90202
(
show subtarget assignments
)
8
cloned
No
AAM13655.1
20153194
CPXV217 CDS
CPXV217 protein
372
serine-protease inhibitor (SPI-1)
Community Requests
1F0C
40.9%
Cowpox virus
host defense modulator
0
IDP90187
(
show subtarget assignments
)
8
cloned
No
AAM13490.1
20153029
CPXV043 CDS
CPXV043 protein
88
IFN resistance, K3L like
Community Requests
1LUZ
90.9%
Cowpox virus
host defense modulator
0
IDP90188
(
show subtarget assignments
)
8
cloned
No
AAM13496.1
20153035
CPXV050 CDS
CPXV050 protein
480
kelch-like protein
Community Requests
3II7
12.3%
Cowpox virus
conserved hypothetical proteins
0
IDP90189
(
show subtarget assignments
)
8
cloned
No
AAM13616.1
20153155
CPXV175 CDS
CPXV175 protein
277
CD47-like putative membrane proteinĀ
Community Requests
2JJS
13%
Cowpox virus
host defense modulator
0
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