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Targets
Filter Targets:
Selection Phase:
No Filter
Community Interest
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM10+
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
[Clostridium] difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
0
1
6
8
Keyword:
Type Keyword
Stage:
No Filter
cloned
crystallized
crystal_structure
diffraction
expressed
in_crystallization_trials
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Screening
No Filter
Yes
No
Remove Filters
Download data as tab-separated value (TSV) file
(which can be used as a input for Microsoft Office Excel and Open Office Calc)
Jump to Target:
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IDP#
NCBI GI
LOCUS TAG
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Page 8 of 60, showing 100 records out of 5973 total, starting on record 701
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CSGID ID
Priority
stage
Screening
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP05136
(
show subtarget assignments
)
1
in_crystallization_trials
No
CD0886
126698463
putative alpha-amylase [Clostridium diff...
621
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
1IZJ
30%
Clostridium difficile
Energy metabolism: Biosynthesis and degradation of polysaccharides
IDP00512
(
show subtarget assignments
)
1
cloned
No
YPO2244
16122472
electron transport complex protein RnfC ...
620
Conserved Gene / Pathway
Phase 2: March 2008
Yersinia pestis
Unclassified
Role category not yet assigned
IDP00089
(
show subtarget assignments
)
0
work_stopped
No
NT01ST0526
16418927
dxs
1-deoxyxylulose-5-phosphate synthase; fl...
620
Essential
Phase 1: October 2007
2O1S
96.3%
Salmonella enterica
Biosynthesis of cofactors, prosthetic groups, and carriers
Other
IDP04569
(
show subtarget assignments
)
1
cloned
No
CPF_2242
110799545
sensor histidine kinase [Clostridium per...
620
conserved gene; putative drug target function;
Phase 4: April 2009
2C2A
10%
Clostridium perfringens
Signal transduction
Two-component systems
IDP00273
(
show subtarget assignments
)
1
selected
No
AF180817_1476-2094
7329982
N/A
NS3 RNA Helicase
619
Polyprotein processing, RNA replication
Phase 3: June 2008
2WZQ
76.4%
Dengue virus
Transcription
N/A
IDP01432
(
show subtarget assignments
)
1
cloned
No
VC1918
15641920
peptidyl-prolyl cis-trans isomerse D
619
Drug Target Function
Phase 2: March 2008
1M5Y
16%
Vibrio cholerae
Protein fate
Protein folding and stabilization
IDP90880
(
show subtarget assignments
)
8
purified
No
YPO3177
16123339
dxs
1-deoxy-D-xylulose-5-phosphate synthase ...
619
Predicted Essential
Community Requests
2O1S
82.7%
Yersinia pestis
IDP91710
(
show subtarget assignments
)
8
selected
No
NP_006353
15487670
NXF1
nuclear RNA export factor 1 isoform 1 [H...
619
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
1KOO
44.6%
Homo sapiens
IDP90204
(
show subtarget assignments
)
8
cloned
No
AAM13452.1
20152991
CPXV006 CDS
CPXV006 protein
619
ankyrin repeat protein
Community Requests
Cowpox virus
conserved hypothetical proteins
0
IDP02128
(
show subtarget assignments
)
1
cloned
No
Cj1334
15792657
hypothetical protein Cj1334 [Campylobact...
619
Known Predicted virulence-O-linked flagellar glycoslyation; PMID:15738950
Phase 3: June 2008
Campylobacter jejuni
Cell envelope
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
IDP00278
(
show subtarget assignments
)
1
selected
No
AAA99437_1474-2092
323469
N/A
NS3 RNA Helicase
619
Polyprotein processing, RNA replication
Phase 3: June 2008
2VBC
78.9%
Dengue virus
Transcription
N/A
IDP02388
(
show subtarget assignments
)
1
soluble
No
YPO1407
16121687
hypothetical protein YPO1407 [Yersinia p...
618
Conserved; Proteomics evidence (Cytoplasmid or periplasmic); Drug target functio...
Phase 3: June 2008
1A9U
25.6%
Yersinia pestis
Cell envelope
Other
IDP00132
(
show subtarget assignments
)
1
purified
No
VC_0288
9654699
VC0288
Vibrio cholerae O1 biovar eltor str. N16...
618
These targets are similar to actual drug targets and will be used mostly for coc...
Phase 1: October 2007
2GP4
53.9%
Vibrio cholerae
Energy metabolism
Entner-Doudoroff
IDP01924
(
show subtarget assignments
)
1
purified
No
lmo0692
16802734
cheA
two-component sensor histidine kinase Ch...
618
Known virulence-Regulation; PMID:15155625
Phase 3: June 2008
1B3Q
26.5%
Listeria monocytogenes
Cellular processes
Chemotaxis and motility
IDP04691
(
show subtarget assignments
)
1
soluble
No
GBAA5067
47530367
sensory box histidine kinase [Bacillus a...
617
putative drug target function;
Phase 4: April 2009
3A0R
10.7%
Bacillus anthracis
Regulatory functions
Protein interactions
IDP05552
(
show subtarget assignments
)
1
soluble
No
lmo0849
16802890
-
amidase [Listeria monocytogenes EGD-e]
616
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1M21
27.6%
Listeria monocytogenes
Central intermediary metabolism: Other
IDP92096
(
show subtarget assignments
)
8
selected
No
TGME49_056970
237831293
vacuolar ATP synthase catalytic subunit ...
616
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
3M4Y
51.1%
Toxoplasma gondii
IDP01396
(
show subtarget assignments
)
1
purified
No
VC0752
15640771
hscA
chaperone protein HscA
616
Conserved Gene / Pathway
Phase 2: March 2008
2KHO
40.9%
Vibrio cholerae
Protein fate
Protein folding and stabilization
IDP02778
(
show subtarget assignments
)
1
cloned
No
CBU_0056
29540679
outer membrane protein TolC, putative [C...
616
Conserved; Drug target functions
Phase 3: June 2008
2VDD
27.4%
Coxiella burnetii
Transport and binding proteins
Unknown substrate
IDP01010
(
show subtarget assignments
)
1
purified
No
STM2539
16765859
hscA
chaperone protein HscA
616
Conserved Gene / Pathway
Phase 2: March 2008
2KHO
40.9%
Salmonella enterica
Protein fate
Protein folding and stabilization
IDP02681
(
show subtarget assignments
)
1
soluble
No
STM3682
16766967
selB
selenocysteinyl-tRNA-specific translatio...
616
Conserved; Drug target functions
Phase 3: June 2008
1D8T
19%
Salmonella enterica
Protein synthesis
Translation factors
IDP01437
(
show subtarget assignments
)
1
purified
No
VC1983
15641985
peptidase, putative
615
Drug Target Function
Phase 2: March 2008
Vibrio cholerae
Protein fate
Degradation of proteins, peptides, and glycopeptides
IDP02217
(
show subtarget assignments
)
1
purified
No
FTT1018c
56708107
dxs
1-deoxy-D-xylulose-5-phosphate synthase ...
615
Conserved; Drug target functions
Phase 3: June 2008
2O1S
56.3%
Francisella tularensis
Biosynthesis of cofactors, prosthetic groups, and carriers
OtherPyridoxine,Thiamine
IDP91801
(
show subtarget assignments
)
8
purified
No
AAQ16565
33356632
DAHP synthetase [Toxoplasma gondii]
615
potential drug target /
The presence of the shikimate pathway in a large number of pathogenic organisms,...
Community Requests
2B7O
28.6%
Toxoplasma gondii
IDP00636
(
show subtarget assignments
)
1
cloned
No
SACOL1118
57285904
typA
GTP-binding protein TypA
615
Drug Target Function
Phase 2: March 2008
3E3X
27.6%
Staphylococcus aureus
Unknown function
General
IDP02199
(
show subtarget assignments
)
1
expressed
No
CBU_1505
29542064
lepA
GTP-binding protein LepA [Coxiella burne...
614
Conserved; Drug target functions
Phase 3: June 2008
3CB4
69.9%
Coxiella burnetii
Unknown function
General
IDP04278
(
show subtarget assignments
)
1
soluble
No
YPO0504
115346313
conserved hypothetical protein [Yersinia...
614
virulence factor; conserved gene;
Phase 4: April 2009
Yersinia pestis
Hypothetical proteins
Conserved
IDP02439
(
show subtarget assignments
)
1
cloned
No
GBAA3892
47529180
serine protease [Bacillus anthracis str....
613
Drug target motif; Vaccine Target; Drug target functions
Phase 3: June 2008
2OXA
16.1%
Bacillus anthracis
Protein fate
Degradation of proteins, peptides, and glycopeptides
IDP04694
(
show subtarget assignments
)
1
soluble
No
GBAA5714
47531051
yycG
sensory box histidine kinase YycG [Bacil...
613
conserved gene; putative drug target function;
Phase 4: April 2009
3A0R
15.3%
Bacillus anthracis
Regulatory functions
Protein interactions
IDP90601
(
show subtarget assignments
)
0
work_stopped
No
YPO0643
16120968
rpoD
RNA polymerase sigma factor RpoD [Yersin...
612
Predicted Essential
Community Requests
3IYD
92%
Yersinia pestis
IDP00340
(
show subtarget assignments
)
1
in_pdb
3TBF
No
FTT0388
56707537
glmS
Glucosamine--fructose-6-phosphate aminot...
612
Drug Target Function
Phase 2: March 2008
3TBF
60.8%
Francisella tularensis
Central intermediary metabolism
Amino sugars
IDP02221
(
show subtarget assignments
)
1
cloned
No
Cj1421c
15792739
sugar transferase [Campylobacter jejuni ...
612
Known Predicted virulence-capsule biosynthesis anmd transport; PMID:15808749
Phase 3: June 2008
Campylobacter jejuni
Cell envelope
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
IDP00320
(
show subtarget assignments
)
1
expressed
No
CBU_0550
29653890
pbpA
penicillin-binding protein 2
612
Drug Target Function
Phase 2: March 2008
1MWR
25.3%
Coxiella burnetii
Cell envelope
Biosynthesis and degradation of murein sacculus and peptidoglycan
IDP01927
(
show subtarget assignments
)
1
expressed
No
CBU_1787
29542344
glmS
glucosamine--fructose-6-phosphate aminot...
611
Conserved; Drug target functions
Phase 3: June 2008
1JXA
58.3%
Coxiella burnetii
Central intermediary metabolism
Amino sugars
IDP01489
(
show subtarget assignments
)
1
cloned
No
VCA0591
15601350
peptide ABC transporter, periplasmic pep...
611
Conserved Gene / Pathway
Phase 2: March 2008
1ZTY
21.8%
Vibrio cholerae
Transport and binding proteins
Amino acids, peptides and amines
IDP05069
(
show subtarget assignments
)
1
cloned
No
CD2789
126700405
cwp66
cell surface protein [Clostridium diffic...
610
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Clostridium difficile
Cell envelope: Other
IDP91522
(
show subtarget assignments
)
8
selected
No
TGGT1_033230
221484314
conserved hypothetical protein [Toxoplas...
610
potential drug target /
Identified in yeast two-hybrid screen with MORN1 as bait and named MIP1 for MORN...
Community Requests
Toxoplasma gondii
IDP91597
(
show subtarget assignments
)
8
cloned
No
BAA24464
2804528
YfiX [Bacillus subtilis]
610
drug resistance /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Bacillus subtilis
IDP02468
(
show subtarget assignments
)
1
cloned
No
Cj0914c
15792243
invasion antigen B [Campylobacter jejuni...
610
Known Predicted virulence-invasion; PMID:10339609
Phase 3: June 2008
Campylobacter jejuni
Cell envelope
Other
IDP05186
(
show subtarget assignments
)
1
cloned
No
CD0120
126697692
glmS
glucosamine--fructose-6-phosphate aminot...
610
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
1JXA
47.1%
Clostridium difficile
Central intermediary metabolism: Amino sugars
IDP91074
(
show subtarget assignments
)
8
cloned
No
MSMEG_5659
118469658
ABC transporter, ATP-binding protein [My...
610
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
3QF4
32.1%
Mycobacterium smegmatis
IDP91070
(
show subtarget assignments
)
8
cloned
No
RP205
15604078
multidrug resistance transporter ATM1 [R...
609
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
2HYD
32%
Rickettsia prowazekii
IDP91077
(
show subtarget assignments
)
8
cloned
No
FTT_0109
56707283
msbA
Lipid A transport protein, ABC transport...
609
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
3B5W
41.2%
Francisella tularensis
IDP91876
(
show subtarget assignments
)
8
purified
No
HMPREF0023_2561
226953731
ftsI
septum formation, penicillin binding pro...
609
Acinetobacter spp. are increasingly problematic pathogens in United States hospi...
Community Requests
3UE3
89.7%
Acinetobacter sp.
IDP00170
(
show subtarget assignments
)
1
soluble
No
VCA0865
15601620
hap
hemagglutinin/protease
609
Virulence
Phase 1: October 2007
1EZM
31.4%
Vibrio cholerae
Cellular processes
Pathogenesis
IDP02539
(
show subtarget assignments
)
1
cloned
No
YPO3200
16123361
malZ
maltodextrin glucosidase [Yersinia pesti...
609
Conserved; CD; Proteomics evidence (Cytoplasmid or periplasmic); Drug target fun...
Phase 3: June 2008
1EA9
33.5%
Yersinia pestis
Energy metabolism
Biosynthesis and degradation of polysaccharides
IDP91995
(
show subtarget assignments
)
8
selected
No
SpneCM_010100003595
298254684
alpha-glycerophosphate oxidase (Glycerol...
608
Predicted surface-exposed protein on Streptococcus pneumoniae str. MDR Canada 19...
Community Requests
2RGO
62%
Streptococcus pneumoniae
IDP01172
(
show subtarget assignments
)
1
purified
No
BA_1206
30255158
pepF-1
oligoendopeptidase F
608
Drug Target Function
Phase 2: March 2008
2QR4
51%
Bacillus anthracis
Protein fate
Degradation of proteins, peptides, and glycopeptides
IDP01773
(
show subtarget assignments
)
1
soluble
No
Cj1466
15792783
flgK
flagellar hook-associated protein FlgK [...
608
Known Predicted virulence-flagella; Possible Vaccine Candidate; PMID:8478066
Phase 3: June 2008
2D4Y
18.7%
Campylobacter jejuni
Hypothetical proteins
Conserved
IDP90405
(
show subtarget assignments
)
8
cloned
No
CT_651
3329100
hypothetical protein [Chlamydia trachoma...
608
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Chlamydia trachomatis
IDP02245
(
show subtarget assignments
)
1
cloned
No
GBAA1751
47527043
asnO-2
asparagine synthetase, glutamine-hydroly...
607
Conserved; Essential; Involved in sporulation; Drug target functions
Phase 3: June 2008
1CT9
25.9%
Bacillus anthracis
Amino acid biosynthesis
Aspartate family
IDP02190
(
show subtarget assignments
)
1
expressed
No
YPO0360
16120695
frdA
fumarate reductase flavoprotein subunit ...
607
Conserved; CD; Proteomics evidence (Cytoplasmid or periplasmic); Drug target fun...
Phase 3: June 2008
1KF6
85.2%
Yersinia pestis
Energy metabolism
Anaerobic
IDP92024
(
show subtarget assignments
)
8
selected
No
TGME49_010840
237843883
arginyl-tRNA synthetase, putative [Toxop...
607
potential drug target /
TDR Toxoplasma Targets (Phase III)
Community Requests
2ZUE
25.9%
Toxoplasma gondii
IDP04434
(
show subtarget assignments
)
1
cloned
No
YPCD1.52
16082740
yscC
outer membrane secretin precursor [Yersi...
607
virulence factor; conserved gene; putative drug target function;
Phase 4: April 2009
2Y9K
6.9%
Yersinia pestis
Unclassified
Role category not yet assigned
IDP05649
(
show subtarget assignments
)
1
expressed
No
Cj0464
6967934
recG
zinc protease-like protein [Campylobacte...
607
potential drug target /
Known drug target or ortholog of known drug target
Phase 5: 2010
1GM5
28.8%
Campylobacter jejuni
DNA metabolism: DNA replication, recombination, and repair
IDP01697
(
show subtarget assignments
)
6
cloned
No
AAC68008
3328839
lpxB
Lipid A Disaccharide Synthase [Chlamydia...
607
LpxB is responsible for the formation of genus-specific lipolpolysaccharide epit...
Phase 3: June 2008
Chlamydia trachomatis
N/A
N/A
IDP91311
(
show subtarget assignments
)
8
purified
No
VP1659
28898433
hypothetical protein VP1659 [Vibrio para...
607
virulence/pathogenesis /
Targets from Vibrio parahaemolyticus and Vibrio vulnificus 1. Predicted essenti...
Community Requests
1R6F
12.8%
Vibrio parahaemolyticus
IDP02502
(
show subtarget assignments
)
1
expressed
No
Cj1341c
15792664
hypothetical protein Cj1341c [Campylobac...
607
Known Predicted virulence-O-linked flagellar glycoslyation; PMID:15738950
Phase 3: June 2008
Campylobacter jejuni
Unclassified
Role category not yet assigned
IDP02581
(
show subtarget assignments
)
1
purified
No
YPO3372
16123521
cysJ
sulfite reductase subunit alpha [Yersini...
606
Conserved; CD; Involved in virulence; Drug target functions
Phase 3: June 2008
1DDG
47.9%
Yersinia pestis
Central intermediary metabolism
Sulfur metabolism
IDP91593
(
show subtarget assignments
)
8
expressed
No
BSU08430
16077910
yfiX
hypothetical protein BSU08430 [Bacillus ...
606
drug resistance /
These targets are similar to actual drug targets and will be used mostly for coc...
Community Requests
Bacillus subtilis
IDP90712
(
show subtarget assignments
)
8
cloned
No
Cj1638
15792943
dnaG
DNA primase [Campylobacter jejuni subsp....
605
Predicted Essential
Community Requests
2AU3
18.3%
Campylobacter jejuni
IDP02081
(
show subtarget assignments
)
1
cloned
No
Cj1340c
15792663
hypothetical protein Cj1340c [Campylobac...
605
Known Predicted virulence-O-linked flagellar glycoslyation; PMID:15738950
Phase 3: June 2008
Campylobacter jejuni
Hypothetical proteins
Conserved
IDP05114
(
show subtarget assignments
)
1
cloned
No
CD2537
126700154
putative membrane-associated 5'-nucleoti...
605
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
3IVD
25.1%
Clostridium difficile
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
IDP01353
(
show subtarget assignments
)
1
expressed
No
VCA0646
15601404
conserved hypothetical protein/hemolysin...
605
Conserved Gene / Pathway
Phase 2: March 2008
Vibrio cholerae
Cellular processes
Pathogenesis
IDP01918
(
show subtarget assignments
)
1
cloned
No
lmo0514
16802557
hypothetical protein lmo0514 [Listeria m...
605
Predicted virulence-Invasion; Predicted involvement or location on the cell wall...
Phase 3: June 2008
2OMZ
17.7%
Listeria monocytogenes
Cell envelope
Other
IDP01872
(
show subtarget assignments
)
1
cloned
No
GBAA5706
47531042
oligoendopeptidase F, putative [Bacillus...
605
Drug target motif; Involved in sporulation; Drug target functions
Phase 3: June 2008
2QR4
29.3%
Bacillus anthracis
Protein fate
Degradation of proteins, peptides, and glycopeptides
IDP05420
(
show subtarget assignments
)
1
soluble
No
lmo0066
16802114
-
hypothetical protein lmo0066 [Listeria m...
604
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1QS1
15.7%
Listeria monocytogenes
Hypothetical proteins: Conserved
IDP05132
(
show subtarget assignments
)
1
cloned
No
CD0262
126697834
flhB
bifunctional flagellar biosynthesis prot...
604
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
2JLH
7.9%
Clostridium difficile
Cellular processes: Chemotaxis and motility
IDP01873
(
show subtarget assignments
)
1
cloned
No
FTT0917
56708018
maeA
malate dehydrogenase [Francisella tulare...
604
Drug Target
Phase 3: June 2008
2AW5
34.8%
Francisella tularensis
Unknown function
Enzymes of unknown specificity
IDP00800
(
show subtarget assignments
)
1
purified
No
SACOL1419
57286070
oligoendopeptidase F, putative
604
Drug Target Function
Phase 2: March 2008
2QR4
23.8%
Staphylococcus aureus
Protein fate
Degradation of proteins, peptides, and glycopeptides
IDP04672
(
show subtarget assignments
)
1
expressed
No
GBAA1482
47526755
sensor histidine kinase [Bacillus anthra...
603
putative drug target function;
Phase 4: April 2009
3A0R
14.1%
Bacillus anthracis
Regulatory functions
Protein interactions
IDP02198
(
show subtarget assignments
)
1
cloned
No
YPO1273
16121558
putative substrate-binding transport pro...
602
Conserved; Proteomics evidence (Cytoplasmid or periplasmic); Drug target functio...
Phase 3: June 2008
1XOC
21.6%
Yersinia pestis
Transport and binding proteins
Amino acids, peptides and amines
IDP02153
(
show subtarget assignments
)
1
expressed
No
CBU_0884
29541475
bipA
virulence regulator BipA [Coxiella burne...
602
Conserved; Drug target functions
Phase 3: June 2008
3E3X
34.6%
Coxiella burnetii
Cellular processes
Pathogenesis
IDP90668
(
show subtarget assignments
)
8
purified
No
Cj0206
15791593
thrS
threonyl-tRNA synthetase [Campylobacter ...
602
Predicted Essential
Community Requests
1QF6
43%
Campylobacter jejuni
IDP92555
(
show subtarget assignments
)
8
selected
No
VV1_0649
27360224
Long-chain-fatty-acid--CoA ligase [Vibri...
601
potential drug target /
Proteins are in a pathway we are investigating for playing a role in symbiont nu...
Community Requests
3TSY
23.6%
Vibrio vulnificus
IDP00693
(
show subtarget assignments
)
1
in_crystallization_trials
No
SACOL2145
57286359
glmS
D-fructose-6-phosphate amidotransferase ...
601
Drug Target Function
Phase 2: March 2008
1JXA
41.4%
Staphylococcus aureus
Central intermediary metabolism
Amino sugars
IDP90089
(
show subtarget assignments
)
8
expressed
No
ZZZ_0005
600
This protein is a component of a type VI secretion system of enteroaggregative E...
Community Requests
Escherichia coli
IDP01677
(
show subtarget assignments
)
1
soluble
No
GBAA0159
47525416
glmS
D-fructose-6-phosphate amidotransferase ...
600
Drug target motif; Essential; Involved in sporulation; Drug target functions
Phase 3: June 2008
1JXA
41.8%
Bacillus anthracis
Central intermediary metabolism
Amino sugars
IDP00302
(
show subtarget assignments
)
1
expressed
No
CBU_1155
29654460
trpBF
N-(5'phosphoribosyl)anthranilate isomera...
600
Drug Target Function
Phase 2: March 2008
1V8Z
38%
Coxiella burnetii
Amino acid biosynthesis
Aromatic amino acid family
IDP90838
(
show subtarget assignments
)
8
cloned
No
YPO2053
16122292
aspS
aspartyl-tRNA synthetase [Yersinia pesti...
598
Predicted Essential
Community Requests
1EQR
80.8%
Yersinia pestis
IDP91084
(
show subtarget assignments
)
8
cloned
No
BA_2444
30262443
ABC transporter, ATP-binding/permease pr...
598
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
3QF4
44.5%
Bacillus anthracis
IDP01994
(
show subtarget assignments
)
1
cloned
No
lmo1290
16803330
hypothetical protein lmo1290 [Listeria m...
598
Predicted virulence-Invasion; Predicted involvement or location on the cell wall...
Phase 3: June 2008
3BZ5
16.4%
Listeria monocytogenes
Cell envelope
Other
IDP00324
(
show subtarget assignments
)
1
cloned
No
Cj1366c
15792689
glmS
D-fructose-6-phosphate amidotransferase ...
598
Drug Target Function
Phase 2: March 2008
1JXA
41.3%
Campylobacter jejuni
Unclassified
Unclassified
IDP02214
(
show subtarget assignments
)
1
soluble
No
Cj0041
15791440
hypothetical protein Cj0041 [Campylobact...
598
Known Predicted virulence-flagella; Possible Vaccine Candidate; PMID:8478066
Phase 3: June 2008
Campylobacter jejuni
Hypothetical proteins
Conserved
IDP91738
(
show subtarget assignments
)
8
selected
No
Q5YB85_STRSG
0
598
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
1I84
15.1%
Streptococcus sp.
IDP02506
(
show subtarget assignments
)
1
soluble
No
FTT0609
56707734
peptidase, M24 family protein [Francisel...
597
Conserved; Drug target functions; Drug target motif
Phase 3: June 2008
3CTZ
37.4%
Francisella tularensis
Protein fate
Degradation of proteins, peptides, and glycopeptides
IDP05213
(
show subtarget assignments
)
1
soluble
No
CD2769
126700385
capsular polysaccharide biosynthesis pro...
597
essential/virulence/pathogenesis /
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesi...
Phase 5: 2010
2GN4
17.4%
Clostridium difficile
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
IDP01931
(
show subtarget assignments
)
1
soluble
No
CBU_0073
29540696
peptidase, M24 family protein [Coxiella ...
597
Conserved; Drug target functions
Phase 3: June 2008
3CTZ
40.6%
Coxiella burnetii
Protein fate
Degradation of proteins, peptides, and glycopeptides
IDP05475
(
show subtarget assignments
)
1
expressed
No
BA_2860
30257458
hydrolase, CocE/NonD family [Bacillus an...
597
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
1LNS
30.7%
Bacillus anthracis
Unknown function: Enzymes of unknown specificity
IDP91689
(
show subtarget assignments
)
8
selected
No
NP_000706
4502503
C4BPA
C4b-binding protein alpha chain precurso...
597
virulence/pathogenesis /
Selected from a set of pathogenic interactions taken from IRefIndex
Community Requests
2GSX
28.8%
Homo sapiens
IDP02644
(
show subtarget assignments
)
1
purified
No
FTT0074
56707253
sdhA
succinate dehydrogenase, catalytic and N...
597
Conserved; Drug target functions
Phase 3: June 2008
1NEK
61.4%
Francisella tularensis
Energy metabolism
TCA cycle
IDP91081
(
show subtarget assignments
)
8
cloned
No
CD2817
126700433
ABC transporter, ATP-binding/permease pr...
596
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
3QF4
39.4%
Clostridium difficile
IDP91078
(
show subtarget assignments
)
8
cloned
No
CBU_0856
29541449
ABC transporter, ATP-binding/permease pr...
596
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
3B5X
42.3%
Coxiella burnetii
IDP91069
(
show subtarget assignments
)
8
cloned
No
SP_1357
15901211
ABC transporter, ATP-binding/permease pr...
596
drug resistance /
The proteins of interest on the list are multi drug resistance transporters. Mu...
Community Requests
3QF4
37.1%
Streptococcus pneumoniae
IDP02427
(
show subtarget assignments
)
1
purified
No
GBAA3553
47528837
pepF-2
oligoendopeptidase F [Bacillus anthracis...
595
Drug target motif; Involved in sporulation; Drug target functions
Phase 3: June 2008
2QR4
37.6%
Bacillus anthracis
Protein fate
Degradation of proteins, peptides, and glycopeptides
IDP90775
(
show subtarget assignments
)
8
cloned
No
YPO0345
16120680
dipZ
thiol:disulfide interchange protein prec...
595
Predicted Essential
Community Requests
1UC7
12.8%
Yersinia pestis
IDP02252
(
show subtarget assignments
)
1
soluble
No
YPO1229
16121516
tsr2
putative methyl-accepting chemotaxis pro...
595
Conserved; Drug target functions
Phase 3: June 2008
3ZX6
27.4%
Yersinia pestis
Cellular processes
Chemotaxis and motility
IDP05179
(
show subtarget assignments
)
1
soluble
No
BA_3367
30257910
LPXTG-motif cell wall anchor domain prot...
595
associated with virulence and/or pathogenesis; vaccine candidate
Phase 5: 2010
Bacillus anthracis
Cell envelope: Other
IDP04432
(
show subtarget assignments
)
1
in_pdb
3OWA
No
GBAA5246
47530551
acyl-CoA dehydrogenase [Bacillus anthrac...
594
conserved gene; putative drug target function;
Phase 4: April 2009
3OWA
100%
Bacillus anthracis
Fatty acid and phospholipid metabolism
Degradation
IDP00968
(
show subtarget assignments
)
1
in_pdb
3M07
No
STM1560
16764904
putative alpha amylase
594
Essential Gene
Phase 2: March 2008
3M07
100%
Salmonella enterica
Cell envelope
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
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