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Targets
Filter Targets:
Selection Phase:
No Filter
Community Interest
Community Requests
January 2009
Phase 1: October 2007
Phase 2: March 2008
Phase 3: June 2008
Phase 4: April 2009
Phase 5: 2010
Tigr Main Category:
No Filter
0
Actin tail formation
Amino acid biosynthesis
Amino acid biosynthesis: Aromatic amino acid family
Amino acid biosynthesis: Aspartate family
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,
Amino acid biosynthesisBiosynthesis of cofactors, prosthetic groups, and carriers,Purines, pyrimidin
Amino acid biosynthesisCell envelope,
Amino acid biosynthesisCentral intermediary metabolism
Amino acid biosynthesisCentral intermediary metabolism,
Amino acid biosynthesisCentral intermediary metabolism,Purines, pyrimidines, nucleosides, and nucleo
Amino acid biosynthesisEnergy metabolism,
Amino acid biosynthesisFatty acid and phospholipid metabolism
Amino acid biosynthesisFatty acid and phospholipid metabolism,
Amino acid biosynthesisRegulatory functions
Amino acid biosynthesisRegulatory functions,
Amino acid biosynthesis: Serine family
Biosynthesis of cofactors, prosthetic groups, and carriers
Biosynthesis of cofactors, prosthetic groups, and carriersCell envelope,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,
Biosynthesis of cofactors, prosthetic groups, and carriersCentral intermediary metabolism,Protein sy
Biosynthesis of cofactors, prosthetic groups, and carriers: Glutathione and analogs
Biosynthesis of cofactors, prosthetic groups, and carriers: Heme, porphyrin, and cobalamin
Biosynthesis of cofactors, prosthetic groups, and carriers: Menaquinone and ubiquinone
Biosynthesis of cofactors, prosthetic groups, and carriers: Other
Biosynthesis of cofactors, prosthetic groups, and carriersPurines, pyrimidines, nucleosides, and nuc
Biosynthesis of cofactors, prosthetic groups, and carriers: Pyridine nucleotides
Biosynthesis of cofactors, prosthetic groups, and carriersRegulatory functions,
Biosynthesis of cofactors, prosthetic groups, and carriers: Riboflavin, FMN, and FAD
Biosynthesis of cofactors, prosthetic groups, and carriers: Thiamine
Cell envelope
Cell envelope: Biosynthesis and degradation of murein sacculus and peptidoglycan
Cell envelope: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Cell envelopeCellular processes
Cell envelopeCellular processes,
Cell envelopeEnergy metabolism,
Cell envelopeFatty acid and phospholipid metabolism,
Cell envelopeMobile and extrachromosomal element functions
Cell envelopeMobile and extrachromosomal element functions,
Cell envelope: Other
Cell envelopeProtein fate
Cell envelopeProtein fate,
Cell envelopeRegulatory functions,Unknown function
Cell envelopeRegulatory functions,Unknown function,
Cell envelope: Surface structures
Cell envelopeTransport and binding proteins,
Cell envelopeTransport and binding proteins,Cellular processes,
Cell envelopeUnclassified,
Cell envelopeUnknown function
Cell envelopeUnknown function,
Cellular processes
Cellular processes: Adaptations to atypical conditions
Cellular processes: Cell adhesion
Cellular processes: Cell division
Cellular processesCentral intermediary metabolism,Signal transduction,
Cellular processes: Chemotaxis and motility
Cellular processes: Detoxification
Cellular processes: DNA transformation
Cellular processesEnergy metabolism,
Cellular processesEnergy metabolism,Protein fate,
Cellular processes: Other
Cellular processes: Pathogenesis
Cellular processesProtein synthesis
Cellular processesProtein synthesis,
Cellular processesRegulatory functions
Cellular processesRegulatory functions,
Cellular processes: Sporulation and germination
Cellular processes: Toxin production and resistance
Cellular processesTranscription
Cellular processesTranscription,
Cellular processesTransport and binding proteins
Cellular processesTransport and binding proteins,
Central intermediary metabolism
Central intermediary metabolism: Amino sugars
Central intermediary metabolismEnergy metabolism,
Central intermediary metabolismEnergy metabolism,Fatty acid and phospholipid metabolism,
Central intermediary metabolismEnergy metabolism,Unknown function,
Central intermediary metabolism: Nitrogen metabolism
Central intermediary metabolism: Other
Central intermediary metabolismProtein fate,
Central intermediary metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Central intermediary metabolismUnknown function
Central intermediary metabolismUnknown function,
Chr.
conserved hypothetical proteins
Conserved Hypothetical proteins
Disrupted reading frame
DNA metabolism
DNA metabolism: Degradation of DNA
DNA metabolism: DNA replication, recombination, and repair
DNA metabolismMobile and extrachromosomal element functions,
DNA metabolismTranscription,
Energy metabolism
Energy metabolism: ATP-proton motive force interconversion
Energy metabolism: Biosynthesis and degradation of polysaccharides
Energy metabolism: Electron transport
Energy metabolismFatty acid and phospholipid metabolism
Energy metabolismFatty acid and phospholipid metabolism,
Energy metabolism: Fermentation
Energy metabolism: Glycolysis/gluconeogenesis
Energy metabolismPurines, pyrimidines, nucleosides, and nucleotides,
Energy metabolismRegulatory functions,Protein synthesis
Energy metabolismRegulatory functions,Protein synthesis,
Energy metabolism: Sugars
Energy metabolism: TCA cycle
Energy metabolismTransport and binding proteins,
Energy metabolismTransport and binding proteins,Central intermediary metabolism,
Energy metabolismUnknown function,
Entry and Cell-Cell Fusion
Fatty acid and phospholipid metabolism
Fatty acid and phospholipid metabolism: Biosynthesis
Fatty acid and phospholipid metabolism: Degradation
host defense modulator
host-range
host-range, binds EGF receptor
host-range determinant, host defense modulator
host range factor
host range factor, host defense modulator
host range, host defense modulator, prevents syncytia
host-range, possible host defense modulator
host range protein
Hypothetical proteins
Hypothetical proteins: Conserved
Hypothetical proteins: Domain
in virion, inactive
Mobile and extrachromosomal element functions
Mobile and extrachromosomal element functions: Other
Mobile and extrachromosomal element functions: Plasmid functions
Mobile and extrachromosomal element functions: Prophage functions
#N/A
N/A
No Data
Protein fate
Protein fateCellular processes,
Protein fate: Degradation of proteins, peptides, and glycopeptides
Protein fateEnergy metabolism,DNA metabolism,
Protein fate: Protein and peptide secretion and trafficking
Protein fate: Protein folding and stabilization
Protein fate: Protein modification and repair
Protein fateRegulatory functions
Protein fateRegulatory functions,
Protein synthesis
Protein synthesis: Ribosomal proteins: synthesis and modification
Protein synthesis: tRNA aminoacylation
Protein synthesis: tRNA and rRNA base modification
Purines, pyrimidines, nucleosides, and nucleotides
Purines, pyrimidines, nucleosides, and nucleotidesEnergy metabolism,
Purines, pyrimidines, nucleosides, and nucleotides: Nucleotide and nucleoside interconversions
Purines, pyrimidines, nucleosides, and nucleotides: Other
Purines, pyrimidines, nucleosides, and nucleotidesProtein synthesis,
Purines, pyrimidines, nucleosides, and nucleotides: Pyrimidine ribonucleotide biosynthesis
Purines, pyrimidines, nucleosides, and nucleotides: Salvage of nucleosides and nucleotides
Purines, pyrimidines, nucleosides, and nucleotides: Sugar-nucleotide biosynthesis and conversions
Purines, pyrimidines, nucleosides, and nucleotidesTransport and binding proteins,
Regulatory functions
Regulatory functionsAmino acid biosynthesis
Regulatory functionsAmino acid biosynthesis,
Regulatory functions: DNA interactions
Regulatory functionsDNA metabolism,
Regulatory functions: Other
Regulatory functions: RNA interactions
Regulatory functionsSignal transduction
Regulatory functionsSignal transduction,
Regulatory functionsTransport and binding proteins,
Signal transduction
Signal transduction: PTS
S-S bond formation pathway
Transcription
Transcription: Degradation of RNA
TranscriptionUnknown function,
Transport and binding proteins
Transport and binding proteins: Amino acids, peptides and amines
Transport and binding proteins: Anions
Transport and binding proteinsBiosynthesis of cofactors, prosthetic groups, and carriers,
Transport and binding proteins: Carbohydrates, organic alcohols, and acids
Transport and binding proteins: Cations and iron carrying compounds
Transport and binding proteins: Nucleosides, purines and pyrimidines
Transport and binding proteins: Other
Transport and binding proteins: Unknown substrate
Unclassified
Unclassified: Role category not yet assigned
unknown
unknown, conserved protein
Unknown function
Unknown function: Enzymes of unknown specificity
Unknown function: General
Viral functions
Viral functions: General
Organism:
No Filter
Acinetobacter baumannii
Acinetobacter baumannii ATCC 17978
Acinetobacter baumannii SDF
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae serovar 5b str. L20
Agrobacterium tumefaciens str. C58
Aquifex aeolicus VF5
Bacillus anthracis str. Ames
Bacillus anthracis str. 'Ames Ancestor'
Bacillus anthracis str. Sterne
Bacillus subtilis
Bacillus subtilis subsp. subtilis str. 168
Bacteroides thetaiotaomicron VPI-5482
Bifidobacterium longum subsp. infantis ATCC 15697
Bordetella pertussis Tohama I
Borrelia burgdorferi B31
Burkholderia mallei ATCC 23344
Burkholderia pseudomallei K96243
Burkholderia pseudomallei MSHR346
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Cell fusing agent virus
Chlamydia muridarum Nigg
Chlamydia trachomatis
Chlamydia trachomatis D/UW-3/CX
Clostridium difficile 630
Clostridium perfringens ATCC 13124
Cowpox virus
Cowpox virus (Brighton Red)
Coxiella burnetii RSA 493
Coxsackievirus B3 (strain Woodruff)
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecalis V583
Enterococcus faecium
Enterococcus faecium DO
Enterococcus gallinarum
Escherichia coli
Escherichia coli 042
Escherichia coli CFT073
Escherichia coli ETEC H10407
Escherichia coli O103:H2 str. 12009
Escherichia coli O157:H7 str. EDL933
Escherichia coli O157:H7 str. Sakai
Escherichia coli str. K-12 substr. MG1655
Escherichia coli UTI89
Francisella novicida U112
Francisella tularensis subsp. holarctica LVS
Francisella tularensis subsp. tularensis SCHU S4
Haemophilus influenzae PittII
Helicobacter pylori
Helicobacter pylori 26695
Helicobacter pylori J99
Herpesvirus saimiri (strain 488)
Homo sapiens
Human echovirus 7
Human herpesvirus 6
Human herpesvirus 8
Human herpesvirus 8 type M
Influenza A virus (A/Aichi/2/1968(H3N2))
Influenza A virus (A/California/07/2009(H1N1))
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Influenza A virus (A/udorn/1972(H3N2))
Influenza B virus (B/Lee/40)
Japanese encephalitis virus
Legionella pneumophila 130b
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Listeria monocytogenes
Listeria monocytogenes EGD-e
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis str. MC2 155
Mycobacterium tuberculosis H37Rv
Myxoma virus (strain Lausanne)
Neisseria gonorrhoeae
Neisseria gonorrhoeae FA 1090
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas aeruginosa PAO1
Pseudomonas aeruginosa UCBPP-PA14
Pseudomonas fluorescens Pf-5
Pseudomonas putida KT2440
Rickettsia prowazekii str. Madrid E
Rio Bravo virus
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Salmonella enterica subsp. enterica serovar Typhimurium
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
SARS coronavirus
Shigella dysenteriae 1012
Shigella dysenteriae Sd197
Shigella flexneri
Shigella flexneri 2a str. 2457T
Shigella flexneri 2a str. 301
Staphylococcus aureus
Staphylococcus aureus subsp. aureus COL
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcus aureus subsp. aureus Mu3
Staphylococcus aureus subsp. aureus Mu50
Staphylococcus aureus subsp. aureus N315
Staphylococcus aureus subsp. aureus NCTC 8325
Staphylococcus aureus subsp. aureus str. Newman
Staphylococcus aureus subsp. aureus USA300_TCH1516
Staphylococcus epidermidis
Staphylococcus epidermidis RP62A
Staphylococcus haemolyticus
St. Louis encephalitis virus (strain MS1-7)
Streptococcus agalactiae 2603V/R
Streptococcus agalactiae A909
Streptococcus agalactiae NEM316
Streptococcus bovis ATCC 700338
Streptococcus downei F0415
Streptococcus dysgalactiae subsp. equisimilis
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equinus ATCC 9812
Streptococcus equi subsp. zooepidemicus
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus infantarius subsp. infantarius ATCC BAA-102
Streptococcus mutans UA159
Streptococcus parauberis KCTC 11537
Streptococcus pneumoniae
Streptococcus pneumoniae G54
Streptococcus pneumoniae Hungary19A-6
Streptococcus pneumoniae P1031
Streptococcus pneumoniae R6
Streptococcus pneumoniae str. Canada MDR_19A
Streptococcus pneumoniae str. Canada MDR_19F
Streptococcus pneumoniae TCH8431/19A
Streptococcus pneumoniae TIGR4
Streptococcus porcinus str. Jelinkova 176
Streptococcus pyogenes
Streptococcus pyogenes M1 GAS
Streptococcus pyogenes MGAS5005
Streptococcus pyogenes NZ131
Streptococcus pyogenes str. Manfredo
Streptococcus sp. 'group G'
Streptococcus suis P1/7
Streptococcus suis SC84
Streptococcus thermophilus LMD-9
Streptococcus thermophilus LMG 18311
Streptococcus uberis 0140J
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Toxoplasma gondii GT1
Toxoplasma gondii ME49
Treponema pallidum subsp. pallidum str. Nichols
Vaccinia virus
Vaccinia virus Copenhagen
Vaccinia virus L-IPV
Vaccinia virus WR
Vibrio cholerae
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio cholerae O395
Vibrio fischeri ES114
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio parahaemolyticus RIMD 2210633
Vibrio sp. AND4
Vibrio vulnificus CMCP6
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis CO92
Yersinia pestis KIM10+
Yersinia pseudotuberculosis IP 32953
Zaire ebolavirus
Species:
No Filter
Acinetobacter baumannii
Acinetobacter haemolyticus
Acinetobacter sp. ATCC 27244
Actinobacillus pleuropneumoniae
Agrobacterium tumefaciens
Aliivibrio fischeri
Aquifex aeolicus
Bacillus anthracis
Bacillus subtilis
Bacteroides thetaiotaomicron
Bifidobacterium longum
Bordetella pertussis
Borrelia burgdorferi
Burkholderia mallei
Burkholderia pseudomallei
Campylobacter jejuni
Cell fusing agent virus
Chlamydia muridarum
Chlamydia trachomatis
[Clostridium] difficile
Clostridium perfringens
Cowpox virus
Coxiella burnetii
Dengue virus
Ectromelia virus
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Enterococcus gallinarum
Escherichia coli
Francisella novicida
Francisella tularensis
Haemophilus influenzae
Helicobacter pylori
Homo sapiens
Human enterovirus B
Human herpesvirus 6
Human herpesvirus 8
Influenza A virus
Influenza B virus
Japanese encephalitis virus
Legionella pneumophila
Listeria monocytogenes
Modoc virus
Monkeypox virus
Montana myotis leukoencephalitis virus
Murid herpesvirus 4
Murray Valley encephalitis virus
Mus musculus
Mycobacterium smegmatis
Mycobacterium tuberculosis
Myxoma virus
Neisseria gonorrhoeae
Proteus mirabilis
Providencia stuartii
Pseudomonas aeruginosa
Pseudomonas fluorescens
Pseudomonas putida
Rickettsia prowazekii
Rio Bravo virus
Saimiriine herpesvirus 2
Salmonella enterica
Severe acute respiratory syndrome-related coronavirus
Shigella dysenteriae
Shigella flexneri
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
St. Louis encephalitis virus
Streptococcus agalactiae
Streptococcus downei
Streptococcus dysgalactiae
Streptococcus equi
Streptococcus equinus
Streptococcus gallolyticus
Streptococcus infantarius
Streptococcus mutans
Streptococcus parauberis
Streptococcus pneumoniae
Streptococcus porcinus
Streptococcus pyogenes
Streptococcus sp. 'group G'
Streptococcus suis
Streptococcus thermophilus
Streptococcus uberis
Streptomyces fradiae
Streptomyces griseus
Streptomyces toyocaensis
synthetic construct
Toxoplasma gondii
Treponema pallidum
Vaccinia virus
Vibrio cholerae
Vibrio mimicus
Vibrio parahaemolyticus
Vibrio sp. AND4
Vibrio vulnificus
Western equine encephalomyelitis virus
West Nile virus
Yellow fever virus
Yersinia pestis
Yersinia pseudotuberculosis
Zaire ebolavirus
Priority:
No Filter
0
1
6
8
Keyword:
Type Keyword
Stage:
No Filter
cloned
crystallized
crystal_structure
diffraction
expressed
in_crystallization_trials
in_pdb
purified
selected
soluble
work_stopped
Clone Location
No Filter
Argonne National Laboratory
Collaborators of the CSGID
J. Craig Venter Institute
Northwestern University
University of Toronto
University of Texas Southwestern Medical Center
University of Virginia
Washington University
Screening
No Filter
Yes
No
Remove Filters
Download data as tab-separated value (TSV) file
(which can be used as a input for Microsoft Office Excel and Open Office Calc)
Jump to Target:
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IDP#
NCBI GI
LOCUS TAG
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Page 9 of 60, showing 100 records out of 5973 total, starting on record 801
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CSGID ID
Priority
stage
Screening
Locus Tag
NCBI GI
Gene
Name
Common Name
Sequence
Length
Justification
Selection
Phase
Homolog
PDB ID
Homolog
Sequence
Identity
Target Organism
TIGR Main Role
TIGR Subrole
Request Person
IDP00998
(
show subtarget assignments
)
1
in_crystallization_trials
No
STM2369
16765696
usg
hypothetical protein STM2369
337
Conserved Gene / Pathway
Phase 2: March 2008
2QZ9
46.6%
Salmonella enterica
Amino acid biosynthesis
Aspartate family
IDP01512
(
show subtarget assignments
)
1
soluble
No
VC1173
15641186
anthranilate synthase component II
203
Drug Target Function
Phase 2: March 2008
1I1Q
57.1%
Vibrio cholerae
Amino acid biosynthesis
Aromatic amino acid family
IDP04446
(
show subtarget assignments
)
1
cloned
No
YPO0653
115346457
glnE
glutamate-ammonia-ligase adenylyltransfe...
951
conserved gene; putative drug target function;
Phase 4: April 2009
3K7D
38.5%
Yersinia pestis
Amino acid biosynthesis
Glutamate family
IDP04318
(
show subtarget assignments
)
1
soluble
No
YPO0540
115346348
ilvH
acetolactate synthase isozyme III small ...
164
virulence factor; conserved gene; putative drug target function;
Phase 4: April 2009
2F1F
87.2%
Yersinia pestis
Amino acid biosynthesis
Pyruvate family
IDP04319
(
show subtarget assignments
)
1
purified
No
YPO1544
115347296
hisA
phosphoribosylformimino-5-aminoimidazole...
245
virulence factor; conserved gene; putative drug target function;
Phase 4: April 2009
2Y85
35.9%
Yersinia pestis
Amino acid biosynthesis
Histidine family
IDP00985
(
show subtarget assignments
)
1
soluble
No
STM2076
16765406
hisA
1-(5-phosphoribosyl)-5-[(5-phosphoribosy...
245
Conserved Gene / Pathway
Phase 2: March 2008
2Y85
35.1%
Salmonella enterica
Amino acid biosynthesis
Histidine family
IDP00984
(
show subtarget assignments
)
1
in_crystallization_trials
No
STM2073
16765403
hisC
histidinol-phosphate aminotransferase
359
Conserved Gene / Pathway
Phase 2: March 2008
1FG3
88%
Salmonella enterica
Amino acid biosynthesis
Histidine family
IDP04293
(
show subtarget assignments
)
1
in_pdb
3OXP
Yes
YPO2569
218929655
phosphotransferase enzyme II, A componen...
147
conserved gene; putative drug target function;
Phase 4: April 2009
3OXP
100%
Yersinia pestis
Amino acid biosynthesis
Aromatic amino acid family
IDP00519
(
show subtarget assignments
)
1
cloned
No
YPO3446
16123594
argI
ornithine carbamoyltransferase subunit I...
335
Conserved Gene / Pathway
Phase 2: March 2008
1AKM
79.1%
Yersinia pestis
Amino acid biosynthesis
Glutamate family
IDP04232
(
show subtarget assignments
)
1
cloned
No
CPF_0693
110799915
aroE
shikimate 5-dehydrogenase [Clostridium p...
271
conserved gene; putative drug target function;
Phase 4: April 2009
3FBT
46.9%
Clostridium perfringens
Amino acid biosynthesis
Aromatic amino acid family
IDP04231
(
show subtarget assignments
)
1
purified
No
CPF_0690
110800421
aroC
chorismate synthase [Clostridium perfrin...
357
conserved gene; putative drug target function;
Phase 4: April 2009
1UM0
39.8%
Clostridium perfringens
Amino acid biosynthesis
Aromatic amino acid family
IDP02159
(
show subtarget assignments
)
1
cloned
No
CBU_1892
29542449
aroK
shikimate kinase [Coxiella burnetii RSA ...
179
Conserved; Drug target functions
Phase 3: June 2008
3TRF
100%
Coxiella burnetii
Amino acid biosynthesis
Aromatic amino acid family
IDP04173
(
show subtarget assignments
)
1
expressed
No
VC2490
15642486
2-isopropylmalate synthase [Vibrio chole...
516
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
3RMJ
39%
Vibrio cholerae
Amino acid biosynthesis
Pyruvate family
IDP00959
(
show subtarget assignments
)
1
soluble
No
STM1303
16764654
argD
bifunctional succinylornithine transamin...
408
Conserved Gene / Pathway
Phase 2: March 2008
2PB0
60.8%
Salmonella enterica
Amino acid biosynthesis
Glutamate family
IDP04176
(
show subtarget assignments
)
1
in_pdb
3OKF
No
VC2628
15642623
aroB
3-dehydroquinate synthase [Vibrio choler...
366
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
3OKF
100%
Vibrio cholerae
Amino acid biosynthesis
Aromatic amino acid family
IDP00107
(
show subtarget assignments
)
1
in_pdb
3DR3
No
NT01SF4834
30043015
argC
N-acetyl-gamma-glutamylphosphate reducta...
334
These targets are similar to actual drug targets and will be used mostly for coc...
Phase 1: October 2007
3DR3
100%
Shigella flexneri
Amino acid biosynthesis
Glutamate family
IDP04160
(
show subtarget assignments
)
1
in_pdb
3NAV
No
VC1169
9655645
tryptophan synthase, alpha subunit [Vibr...
268
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
3NAV
100%
Vibrio cholerae
Amino acid biosynthesis
Aromatic amino acid family
IDP04161
(
show subtarget assignments
)
1
cloned
No
VC1172
9655648
anthranilate phosphoribosyltransferase [...
353
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
1KGZ
59.5%
Vibrio cholerae
Amino acid biosynthesis
Aromatic amino acid family
IDP00950
(
show subtarget assignments
)
1
soluble
No
STM1119
16764477
wraB
TrpR binding protein WrbA
198
Conserved Gene / Pathway
Phase 2: March 2008
2R96
94.4%
Salmonella enterica
Amino acid biosynthesis
Aromatic amino acid family
IDP04167
(
show subtarget assignments
)
1
cloned
No
VC1977
9656518
aspartate aminotransferase, putative [Vi...
404
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
1XI9
40.8%
Vibrio cholerae
Amino acid biosynthesis
Aspartate family
IDP04155
(
show subtarget assignments
)
1
cloned
No
VC0547
9654975
aspartokinase, alpha and beta subunits [...
395
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
3L76
39.8%
Vibrio cholerae
Amino acid biosynthesis
Aspartate family
IDP04177
(
show subtarget assignments
)
1
crystallized
No
VC2629
9657219
shikimate kinase [Vibrio cholerae O1 bio...
174
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
1KAG
81%
Vibrio cholerae
Amino acid biosynthesis
Aromatic amino acid family
IDP00946
(
show subtarget assignments
)
1
expressed
No
STM0978
16764338
aroA
3-phosphoshikimate 1-carboxyvinyltransfe...
427
Conserved Gene / Pathway
Phase 2: March 2008
1G6S
89.5%
Salmonella enterica
Amino acid biosynthesis
Aromatic amino acid family
IDP00945
(
show subtarget assignments
)
0
work_stopped
No
STM0977
16764337
serC
phosphoserine aminotransferase
362
Conserved Gene / Pathway
Phase 2: March 2008
3QM2
100%
Salmonella enterica
Amino acid biosynthesis
Serine family
IDP04122
(
show subtarget assignments
)
1
in_pdb
3OJC
Yes
YPO2758
115348441
putative aspartate/glutamate racemase [Y...
231
conserved gene; putative drug target function;
Phase 4: April 2009
3OJC
100%
Yersinia pestis
Amino acid biosynthesis
Aspartate family
IDP04136
(
show subtarget assignments
)
1
diffraction
No
GBAA4258
47529551
5-methylthio-3-oxo-1-penten-1,2-diol dio...
170
putative drug target function;
Phase 4: April 2009
1ZRR
31.8%
Bacillus anthracis
Amino acid biosynthesis
Aspartate family
IDP04090
(
show subtarget assignments
)
1
crystallized
No
CPF_0694
110800453
aroK
shikimate kinase [Clostridium perfringen...
167
conserved gene; putative drug target function;
Phase 4: April 2009
2PT5
34.1%
Clostridium perfringens
Amino acid biosynthesis
Aromatic amino acid family
IDP00012
(
show subtarget assignments
)
1
in_crystallization_trials
No
BA_2953
61211623
3-phosphoshikimate 1-carboxyvinyltransfe...
429
Drug Target Homolog
Phase 1: October 2007
3RMT
66.2%
Bacillus anthracis
Amino acid biosynthesis
Aromatic amino acid family
IDP04049
(
show subtarget assignments
)
1
soluble
No
VC1132
15641145
hisG
ATP phosphoribosyltransferase [Vibrio ch...
304
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
1H3D
65.8%
Vibrio cholerae
Amino acid biosynthesis
Histidine family
IDP01143
(
show subtarget assignments
)
1
in_pdb
3R8Y
No
BA_4194
30258698
2,3,4,5-tetrahydropyridine-2-carboxylate...
240
Drug Target Function
Phase 2: March 2008
3R8Y
100%
Bacillus anthracis
Amino acid biosynthesis
Aspartate family
IDP02836
(
show subtarget assignments
)
1
crystallized
No
GBAA4423
47529716
aroQ
3-dehydroquinate dehydratase [Bacillus a...
146
Conserved; Drug target functions
Phase 3: June 2008
1GQO
57.5%
Bacillus anthracis
Amino acid biosynthesis
Aromatic amino acid family
IDP00482
(
show subtarget assignments
)
1
in_crystallization_trials
No
YPO1758
16122014
manX
PTS system, mannose-specific IIAB compon...
324
Virulence Associated Factor
Phase 2: March 2008
2JZH
45.4%
Yersinia pestis
Amino acid biosynthesis
Aromatic amino acid family
IDP00481
(
show subtarget assignments
)
1
expressed
No
YPO3558
16123702
gltD
glutamate synthase subunit beta
472
Virulence Associated Factor
Phase 2: March 2008
2VDC
43.2%
Yersinia pestis
Amino acid biosynthesis
Glutamate family
IDP00901
(
show subtarget assignments
)
1
in_crystallization_trials
No
STM0004
16763394
thrC
threonine synthase
428
Conserved Gene / Pathway
Phase 2: March 2008
1VB3
93.5%
Salmonella enterica
Amino acid biosynthesis
Aspartate family
IDP02138
(
show subtarget assignments
)
1
expressed
No
Cj0580c
15791940
coproporphyrinogen III oxidase [Campylob...
355
Predicted virulence-Iron Scavenging Mechanisms
Phase 3: June 2008
1OLT
22.5%
Campylobacter jejuni
Amino acid biosynthesis
Pyruvate family
IDP00898
(
show subtarget assignments
)
1
purified
No
STM2114
16765444
wcaB
putative colanic acid biosynthesis acety...
162
Drug Target Function
Phase 2: March 2008
3GVD
33.3%
Salmonella enterica
Amino acid biosynthesis
Serine family
IDP00477
(
show subtarget assignments
)
1
purified
No
YPO3845
16123980
dapF
diaminopimelate epimerase
274
Conserved Gene / Pathway
Phase 2: March 2008
1GQZ
75.9%
Yersinia pestis
Amino acid biosynthesis
Aspartate family
IDP01984
(
show subtarget assignments
)
1
expressed
No
CBU_0831
29541425
asnB-1
asparagine synthetase B, glutamine-hydro...
632
Conserved; Drug target functions
Phase 3: June 2008
1CT9
18.8%
Coxiella burnetii
Amino acid biosynthesis
Aspartate family
IDP02815
(
show subtarget assignments
)
1
soluble
No
GBAA4880
47530173
argG
argininosuccinate synthase [Bacillus ant...
401
Conserved; Drug target functions
Phase 3: June 2008
1VL2
46.7%
Bacillus anthracis
Amino acid biosynthesis
Glutamate family
IDP02783
(
show subtarget assignments
)
1
expressed
No
FTT0425c
56707572
asd
aspartate-semialdehyde dehydrogenase [Fr...
364
Conserved; Drug target functions
Phase 3: June 2008
1NWC
50%
Francisella tularensis
Amino acid biosynthesis
Aspartate family
IDP00877
(
show subtarget assignments
)
1
crystallized
No
STM3015
16766317
ygeA
putative racemase
235
Conserved Gene / Pathway
Phase 2: March 2008
3OJC
56.6%
Salmonella enterica
Amino acid biosynthesis
Aspartate family
IDP02833
(
show subtarget assignments
)
1
cloned
No
GBAA4561
47529857
aroE
shikimate 5-dehydrogenase [Bacillus anth...
308
Conserved; Drug target functions
Phase 3: June 2008
2EGG
49.4%
Bacillus anthracis
Amino acid biosynthesis
Aromatic amino acid family
IDP00461
(
show subtarget assignments
)
1
expressed
No
YPO3285
16123440
tyrA
bifunctional chorismate mutase/prephenat...
373
Conserved Gene / Pathway
Phase 2: March 2008
2PV7
47.2%
Yersinia pestis
Amino acid biosynthesis
Aromatic amino acid family
IDP01915
(
show subtarget assignments
)
1
cloned
No
GBAA1421
47777930
leuB
3-isopropylmalate dehydrogenase [Bacillu...
354
Conserved; Involved in sporulation; Drug target functions
Phase 3: June 2008
3U1H
60.3%
Bacillus anthracis
Amino acid biosynthesis
Pyruvate family
IDP00460
(
show subtarget assignments
)
1
in_crystallization_trials
No
YPO0914
16121219
serA
D-3-phosphoglycerate dehydrogenase
413
Virulence Associated Factor
Phase 2: March 2008
1YBA
83.8%
Yersinia pestis
Amino acid biosynthesis
Serine family
IDP02764
(
show subtarget assignments
)
1
expressed
No
CBU_0525
29541128
serC
phosphoserine aminotransferase [Coxiella...
360
Conserved; Drug target functions
Phase 3: June 2008
3QBO
53.6%
Coxiella burnetii
Amino acid biosynthesis
Serine family
IDP01917
(
show subtarget assignments
)
1
soluble
No
GBAA1429
47526701
hisA
1-(5-phosphoribosyl)-5-[(5-phosphoribosy...
239
Conserved; Involved in sporulation; Drug target functions
Phase 3: June 2008
1VZW
36.5%
Bacillus anthracis
Amino acid biosynthesis
Histidine family
IDP01913
(
show subtarget assignments
)
1
cloned
No
GBAA1426
47526698
hisD
histidinol dehydrogenase [Bacillus anthr...
429
Conserved; Drug target functions
Phase 3: June 2008
1K75
39.2%
Bacillus anthracis
Amino acid biosynthesis
Histidine family
IDP02102
(
show subtarget assignments
)
1
cloned
No
CBU_0503
29541108
glnA
glutamine synthetase [Coxiella burnetii ...
359
Conserved; Drug target functions
Phase 3: June 2008
3FKY
49.9%
Coxiella burnetii
Amino acid biosynthesis
Glutamate family
IDP00856
(
show subtarget assignments
)
1
purified
No
STM0388
16763768
aroL
shikimate kinase II
181
Conserved Gene / Pathway
Phase 2: March 2008
1SHK
48.6%
Salmonella enterica
Amino acid biosynthesis
Aromatic amino acid family
IDP02736
(
show subtarget assignments
)
1
cloned
No
GBAA4352
47778283
argD
acetylornithine aminotransferase [Bacill...
386
Conserved; Essential; Drug target functions
Phase 3: June 2008
2E54
44%
Bacillus anthracis
Amino acid biosynthesis
Glutamate family
IDP01731
(
show subtarget assignments
)
1
expressed
No
CBU_1222
29541792
dapA
dihydrodipicolinate synthase [Coxiella b...
289
Conserved; Drug target functions
Phase 3: June 2008
3QZE
55.2%
Coxiella burnetii
Amino acid biosynthesis
Aspartate family
IDP01728
(
show subtarget assignments
)
1
expressed
No
CBU_0840
29541434
asnB-2
asparagine synthetase B, glutamine-hydro...
637
Conserved; Drug target functions
Phase 3: June 2008
1Q15
13%
Coxiella burnetii
Amino acid biosynthesis
Aspartate family
IDP04159
(
show subtarget assignments
)
1
cloned
No
VC1134
15641147
histidinol-phosphate aminotransferase [V...
346
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
1FG3
59.8%
Vibrio cholerae
Amino acid biosynthesis
Histidine family
IDP02718
(
show subtarget assignments
)
1
cloned
No
GBAA3833
47529118
glnA
glutamine synthetase, type I [Bacillus a...
444
Conserved; Involved in sporulation; Drug target functions
Phase 3: June 2008
3QAJ
86.7%
Bacillus anthracis
Amino acid biosynthesis
Glutamate family
IDP00847
(
show subtarget assignments
)
1
expressed
No
SACOL1404
57284558
trpG
anthranilate synthase, glutamine amidotr...
188
Drug Target Function
Phase 2: March 2008
1QDL
34.2%
Staphylococcus aureus
Amino acid biosynthesis
Aromatic amino acid family
IDP02113
(
show subtarget assignments
)
1
in_crystallization_trials
No
STM3901
16767177
ilvG
acetolactate synthase 2 catalytic subuni...
548
Conserved; Drug target functions
Phase 3: June 2008
1YBH
46.7%
Salmonella enterica
Amino acid biosynthesis
Pyruvate family
IDP02676
(
show subtarget assignments
)
1
crystallized
No
GBAA1539
47526813
hisC-1
histidinol-phosphate aminotransferase [B...
370
Conserved; Involved in sporulation; Drug target functions
Phase 3: June 2008
3FFH
46.2%
Bacillus anthracis
Amino acid biosynthesis
Histidine family
IDP01883
(
show subtarget assignments
)
1
expressed
No
STM0116
16763506
ilvI
acetolactate synthase 3 catalytic subuni...
553
Conserved; Drug target functions
Phase 3: June 2008
1JSC
43.7%
Salmonella enterica
Amino acid biosynthesis
Pyruvate family
IDP02669
(
show subtarget assignments
)
1
purified
No
GBAA1568
50196927
aspB
aspartate aminotransferase [Bacillus ant...
395
Essential; Involved in sporulation; Drug target functions
Phase 3: June 2008
1J32
45.8%
Bacillus anthracis
Amino acid biosynthesis
Aspartate family
IDP00444
(
show subtarget assignments
)
1
cloned
No
YPO0342
16120677
putative oxidoreductase Fe-S binding sub...
671
Drug Target Function
Phase 2: March 2008
2VDC
28.8%
Yersinia pestis
Amino acid biosynthesis
Glutamate family
IDP04174
(
show subtarget assignments
)
1
diffraction
No
VC2508
15642504
ornithine carbamoyltransferase [Vibrio c...
334
drug target; conserved gene; putative drug target function;
Phase 4: April 2009
3UPD
82.6%
Vibrio cholerae
Amino acid biosynthesis
Glutamate family
IDP02670
(
show subtarget assignments
)
1
cloned
No
GBAA4353
47529649
argB
acetylglutamate kinase [Bacillus anthrac...
255
Conserved; Drug target functions
Phase 3: June 2008
2BTY
43.1%
Bacillus anthracis
Amino acid biosynthesis
Glutamate family
IDP02667
(
show subtarget assignments
)
1
cloned
No
lmo0565
16802608
hisH
imidazole glycerol phosphate synthase su...
208
Predicted Essential-Modeling; Predicted involvement in glycosyl group metabolism...
Phase 3: June 2008
1OX4
33.5%
Listeria monocytogenes
Amino acid biosynthesis
Histidine family
IDP02649
(
show subtarget assignments
)
1
purified
No
STM1795
16765136
putative glutamic dehyrogenase-like prot...
441
Drug target motif; Conserved; Drug target functions
Phase 3: June 2008
3AOE
58.5%
Salmonella enterica
Amino acid biosynthesis
Glutamate family
IDP00441
(
show subtarget assignments
)
1
expressed
No
YPO2207
16122435
trpG
anthranilate synthase component II
192
Drug Target Function
Phase 2: March 2008
1I7Q
87.5%
Yersinia pestis
Amino acid biosynthesis
Aromatic amino acid family
IDP00440
(
show subtarget assignments
)
1
purified
No
YPO2208
16122436
trpE
anthranilate synthase component I
521
Conserved Gene / Pathway
Phase 2: March 2008
1I7Q
79.7%
Yersinia pestis
Amino acid biosynthesis
Aromatic amino acid family
IDP02652
(
show subtarget assignments
)
1
expressed
No
GBAA1422
47526694
leuC
isopropylmalate isomerase large subunit ...
464
Conserved; Drug target functions
Phase 3: June 2008
2B3X
22%
Bacillus anthracis
Amino acid biosynthesis
Pyruvate family
IDP02625
(
show subtarget assignments
)
1
cloned
No
GBAA4457
47529752
aroK
shikimate kinase [Bacillus anthracis str...
165
Conserved; Drug target functions
Phase 3: June 2008
1ZUH
35.2%
Bacillus anthracis
Amino acid biosynthesis
Aromatic amino acid family
IDP01631
(
show subtarget assignments
)
1
soluble
No
CBU_2024
29542577
cystathionine beta-synthase, putative [C...
316
Conserved; Drug target functions
Phase 3: June 2008
1JBQ
60.9%
Coxiella burnetii
Amino acid biosynthesis
Serine family
IDP00434
(
show subtarget assignments
)
1
cloned
No
YPO0796
16121108
lysA
diaminopimelate decarboxylase
420
Drug Target Function
Phase 2: March 2008
1KNW
76.9%
Yersinia pestis
Amino acid biosynthesis
Aspartate family
IDP00433
(
show subtarget assignments
)
1
purified
No
YPO1545
16121818
hisH
imidazole glycerol phosphate synthase su...
196
Drug Target Function
Phase 2: March 2008
1GPW
35.3%
Yersinia pestis
Amino acid biosynthesis
Histidine family
IDP00804
(
show subtarget assignments
)
1
expressed
No
SACOL1787
57286221
bifunctional 3-deoxy-7-phosphoheptulonat...
363
Drug Target Function
Phase 2: March 2008
3NVT
66.9%
Staphylococcus aureus
Amino acid biosynthesis
Aromatic amino acid family
IDP02612
(
show subtarget assignments
)
0
work_stopped
No
GBAA5170
50196964
dapF
diaminopimelate epimerase [Bacillus anth...
288
Essential; Involved in sporulation; Drug target functions
Phase 3: June 2008
2OTN
100%
Bacillus anthracis
Amino acid biosynthesis
Aspartate family
IDP00799
(
show subtarget assignments
)
1
expressed
No
SACOL1403
57284557
trpE
anthranilate synthase component I
468
Drug Target Function
Phase 2: March 2008
1QDL
33.3%
Staphylococcus aureus
Amino acid biosynthesis
Aromatic amino acid family
IDP02636
(
show subtarget assignments
)
1
expressed
No
YPO3722
16123860
metH
B12-dependent methionine synthase [Yersi...
1231
CD; Drug target functions
Phase 3: June 2008
1K7Y
40.1%
Yersinia pestis
Amino acid biosynthesis
Aspartate family
IDP01627
(
show subtarget assignments
)
1
cloned
No
GBAA0530
50196914
glutamate synthase, large subunit, putat...
1478
Conserved; Drug target functions
Phase 3: June 2008
1EA0
29.7%
Bacillus anthracis
Amino acid biosynthesis
Glutamate family
IDP00088
(
show subtarget assignments
)
8
in_crystallization_trials
No
NT01ST3082
16421025
dapE
N-succinyl-diaminopimelate deacylase
375
Essential
Community Requests
3IC1
61.9%
Salmonella enterica
Amino acid biosynthesis
Aspartate family
IDP01920
(
show subtarget assignments
)
1
expressed
No
CBU_1156
29541728
trpA
tryptophan synthase, alpha subunit [Coxi...
267
Conserved; Drug target functions
Phase 3: June 2008
1V7Y
35.6%
Coxiella burnetii
Amino acid biosynthesis
Aromatic amino acid family
IDP02093
(
show subtarget assignments
)
1
in_crystallization_trials
No
GBAA1970
47527265
thrB
homoserine kinase [Bacillus anthracis st...
297
Conserved; Involved in sporulation; Drug target functions
Phase 3: June 2008
3HUL
46.8%
Bacillus anthracis
Amino acid biosynthesis
Aspartate family
IDP01413
(
show subtarget assignments
)
1
purified
No
VC1174
15641187
anthranilate synthase component I
523
Drug Target Function
Phase 2: March 2008
1I1Q
59.3%
Vibrio cholerae
Amino acid biosynthesis
Aromatic amino acid family
IDP01866
(
show subtarget assignments
)
1
crystallized
No
FTT1772c
56708766
trpA
tryptophan synthase subunit alpha [Franc...
269
Drug Target
Phase 3: June 2008
3NAV
61%
Francisella tularensis
Amino acid biosynthesis
Aromatic amino acid family
IDP02535
(
show subtarget assignments
)
1
expressed
No
GBAA0088
47525343
cysE
serine O-acetyltransferase [Bacillus ant...
221
Essential; Involved in sporulation; Drug target functions
Phase 3: June 2008
3GVD
36.2%
Bacillus anthracis
Amino acid biosynthesis
Serine family
IDP02524
(
show subtarget assignments
)
1
in_crystallization_trials
No
GBAA1852
47527143
ilvC-2
ketol-acid reductoisomerase [Bacillus an...
335
Conserved; Essential; Involved in sporulation; Drug target functions
Phase 3: June 2008
1NP3
56.1%
Bacillus anthracis
Amino acid biosynthesis
Pyruvate family
IDP02541
(
show subtarget assignments
)
1
expressed
No
CBU_1709
29542267
dapB
dihydrodipicolinate reductase [Coxiella ...
239
Conserved; Drug target functions
Phase 3: June 2008
1YL5
42.3%
Coxiella burnetii
Amino acid biosynthesis
Aspartate family
IDP01759
(
show subtarget assignments
)
1
cloned
No
Cj1433c
15792751
hypothetical protein Cj1433c [Campylobac...
368
Known Predicted virulence-capsule biosynthesis anmd transport; PMID:15808749
Phase 3: June 2008
Campylobacter jejuni
Amino acid biosynthesis
Serine family
IDP02525
(
show subtarget assignments
)
1
in_pdb
4EP1
No
GBAA4351
47529646
argF
ornithine carbamoyltransferase [Bacillus...
316
Conserved; Drug target functions
Phase 3: June 2008
4EP1
99.7%
Bacillus anthracis
Amino acid biosynthesis
Glutamate family
IDP01013
(
show subtarget assignments
)
1
purified
No
STM2670
16765985
aroF
phospho-2-dehydro-3-deoxyheptonate aldol...
356
Conserved Gene / Pathway
Phase 2: March 2008
1GG1
51.4%
Salmonella enterica
Amino acid biosynthesis
Aromatic amino acid family
IDP00749
(
show subtarget assignments
)
1
in_pdb
3PGY
No
SACOL2105
57286321
glyA
serine hydroxymethyltransferase
412
Drug Target Function
Phase 2: March 2008
3PGY
99.8%
Staphylococcus aureus
Amino acid biosynthesis
Serine family
IDP01921
(
show subtarget assignments
)
1
expressed
No
CBU_1154
29541726
trpC
indole-3-glycerol phosphate synthase [Co...
257
Conserved; Drug target functions
Phase 3: June 2008
3QJA
37%
Coxiella burnetii
Amino acid biosynthesis
Aromatic amino acid family
IDP02492
(
show subtarget assignments
)
1
crystallized
No
FTT1559c
56708586
proC
pyrroline-5-carboxylate reductase [Franc...
274
Conserved; Drug target functions
Phase 3: June 2008
3TRI
37.6%
Francisella tularensis
Amino acid biosynthesis
Glutamate family
IDP01844
(
show subtarget assignments
)
1
soluble
No
GBAA1428
47526700
hisH
imidazole glycerol phosphate synthase su...
209
Drug target motif; Conserved; Involved in sporulation; Drug target functions
Phase 3: June 2008
1GPW
35.9%
Bacillus anthracis
Amino acid biosynthesis
Histidine family
IDP01842
(
show subtarget assignments
)
1
in_pdb
3SLH
4EGR
3ROI
Yes
CBU_0526
29541129
aroA
3-phosphoshikimate 1-carboxyvinyltransfe...
438
Conserved; Drug target functions
Phase 3: June 2008
3ROI
100%
Coxiella burnetii
Amino acid biosynthesis
Aromatic amino acid family
IDP02497
(
show subtarget assignments
)
1
cloned
No
FTT1287
56708346
cbs
cystathionine beta-synthase (cystein syn...
307
Conserved; Drug target functions
Phase 3: June 2008
4AEC
33.2%
Francisella tularensis
Amino acid biosynthesis
Serine family
IDP02501
(
show subtarget assignments
)
1
cloned
No
GBAA1250
47526516
trpD
anthranilate phosphoribosyltransferase [...
341
Conserved; Involved in sporulation; Drug target functions
Phase 3: June 2008
1VQU
39.6%
Bacillus anthracis
Amino acid biosynthesis
Aromatic amino acid family
IDP01091
(
show subtarget assignments
)
1
in_crystallization_trials
No
STM4578
16767819
serB
phosphoserine phosphatase
322
Conserved Gene / Pathway
Phase 2: March 2008
3N28
47.2%
Salmonella enterica
Amino acid biosynthesis
Serine family
IDP02483
(
show subtarget assignments
)
1
cloned
No
CBU_0517
29541120
aspB
aspartate aminotransferase [Coxiella bur...
394
Conserved; Drug target functions
Phase 3: June 2008
1BJW
43.9%
Coxiella burnetii
Amino acid biosynthesis
Aspartate family
IDP02467
(
show subtarget assignments
)
1
soluble
No
GBAA3937
47529228
asd-2
aspartate-semialdehyde dehydrogenase [Ba...
348
Conserved; Essential; Involved in sporulation; Drug target functions
Phase 3: June 2008
2GYY
60.6%
Bacillus anthracis
Amino acid biosynthesis
Aspartate family
IDP02487
(
show subtarget assignments
)
1
cloned
No
GBAA4218
47529511
metE
5-methyltetrahydropteroyltriglutamate--h...
762
Conserved; Involved in sporulation; Drug target functions
Phase 3: June 2008
2NQ5
51.3%
Bacillus anthracis
Amino acid biosynthesis
Aspartate family
IDP01087
(
show subtarget assignments
)
1
cloned
No
STM4465
16767710
ornithine carbamoyltransferase
334
Conserved Gene / Pathway
Phase 2: March 2008
3UPD
75.7%
Salmonella enterica
Amino acid biosynthesis
Glutamate family
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Target Id
Locus Tag
Priority
Stage
Has Screening
Ncbi Gi
Gene Name
Common Name
Length
Justification
Project
Homolog Pdb Id
Homolog Sequence Identity
Organism
Tigr Main Role
Tigr Sub Role
