Target   IDP00021

Stage

in_pdb   : 3SG1

Locus Tag/Selection DB Lookup

BA_5529  

NCBI Protein Lookup

gi: 81714862   accession: Q81K13  

Organism

Bacillus anthracis str. Ames  

Common Name

UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 (Enoylpyruvate transferase 1) (UDP-N-acetylglucosamine enolpyruvyl transferase 1) (EPT 1)  

Gene Name

 

NCBI Gene Lookup

 

NCBI Annotation

 

TIGR Main Role/Annotations

Cell envelope  

TIGR Sub Role

Biosynthesis and degradation of murein sacculus and peptidoglycan  

Comment

 

Selection Phase

Phase 1: October 2007  

Date Approved

Dec 13, 2007  

Justification for Selection

Drug Target Homolog  

Justification Codes

 

Priority

1  

Sequence Length

434  

(Subtargets)

 

pI

5.53  

Molecular Weight

46.8 kDa  

Sequence

(Check Homologs)

MEKIIVRGGK RLNGTVRVEG AKNAVLPIIA AALLASDGKN VLSEVPVLSD VYTINEVLRH LNAEVVFENN QVTIDASKEL NIEAPFEYVR KMRASVQVMG PLLARNGRAR IALPGGCAIG SRPIDQHLKG FEAMGAKVQV GNGFVEAYVE GELKGAKIYL DFPSVGATEN IMSAATLAKG TTILENAAKE PEIVDLANFL NAMGAKVRGA GTGTIRIEGV DKLYGANHSI IPDRIEAGTF MVAAAITGGD ILIENAVPEH LRSITAKMEE MGVKIIEENE GVRVIGPDKL KAVDIKTMPH PGFPTDMQSQ MMALLLQADG TSMITETVFE NRFMHVEEFR RMNADIKIEG RSVIMNGPNS LQGAEVGATD LRAAAALILA GLVSEGYTRV TELKHLDRGY VDFHKKLAAL GATIERVNEK VEEVKEQEVS DLHA  

DNA Sequence

TTGGAA AAGATC ATCGTC CGTGGC GGAAAG CGGTTA AACGGC ACAGTG CGTGTT GAGGGC GCAAAA AATGCT GTATTA CCTATA ATCGCT GCAGCC CTATTA GCGAGT GATGGA AAGAAT GTACTA TCTGAA GTACCA GTTTTG TCTGAT GTATAC ACAATT AATGAG GTATTA CGTCAT TTAAAT GCTGAA GTCGTA TTTGAA AATAAC CAAGTA ACAATC GATGCT TCTAAA GAGCTA AACATT GAAGCA CCATTT GAATAT GTACGT AAAATG CGTGCA TCTGTT CAAGTA ATGGGA CCATTA TTAGCA CGTAAC GGTCGT GCTCGT ATTGCA CTTCCT GGTGGA TGTGCA ATTGGT TCACGT CCAATT GACCAA CATTTA AAAGGC TTCGAA GCAATG GGAGCA AAAGTA CAGGTT GGTAAC GGTTTT GTTGAG GCATAC GTTGAG GGAGAA CTAAAA GGAGCT AAAATT TATTTA GACTTC CCAAGC GTGGGC GCAACA GAAAAT ATTATG TCTGCA GCTACA TTAGCA AAAGGG ACAACA ATCCTT GAAAAC GCAGCG AAAGAA CCAGAA ATCGTT GACTTA GCTAAC TTCTTA AATGCG ATGGGA GCGAAA GTACGC GGAGCT GGAACT GGAACG ATTCGT ATCGAA GGCGTT GATAAA TTATAT GGTGCA AACCAC TCTATT ATTCCT GACCGT ATTGAA GCGGGA ACATTC ATGGTT GCAGCA GCAATT ACTGGT GGAGAC ATCTTA ATTGAA AATGCT GTACCT GAACAT TTACGC TCAATT ACAGCG AAAATG GAAGAA ATGGGT GTTAAA ATTATC GAAGAA AATGAA GGTGTA CGTGTT ATCGGC CCAGAT AAGTTA AAAGCG GTTGAT ATTAAA ACTATG CCTCAC CCAGGT TTCCCA ACAGAC ATGCAA TCACAA ATGATG GCATTA TTACTA CAAGCT GATGGC ACAAGT ATGATT ACAGAA ACGGTA TTTGAA AACCGC TTTATG CACGTT GAAGAA TTCCGT CGTATG AATGCT GATATT AAAATC GAAGGT CGTTCT GTTATT ATGAAC GGTCCA AACAGC TTACAA GGTGCT GAAGTA GGCGCA ACTGAT TTACGT GCTGCA GCTGCA TTAATC TTAGCT GGTTTA GTATCA GAAGGT TACACT CGTGTA ACTGAG TTAAAG CATCTT GACCGT GGTTAT GTAGAT TTCCAT AAGAAA TTAGCT GCATTA GGTGCA ACTATT GAACGT GTAAAC GAAAAA GTAGAA GAAGTG AAAGAA CAAGAA GTTTCT GATCTT CACGCT TAA  

Inserted

Dec 19, 2007