Target   IDP00340

Stage

in_pdb   : 3TBF

Locus Tag/Selection DB Lookup

FTT0388  

NCBI Protein Lookup

gi: 56707537   accession: YP_169433  

Organism

Francisella tularensis subsp. tularensis SCHU S4  

Common Name

Glucosamine--fructose-6-phosphate aminotransferase  

Gene Name

glmS  

NCBI Gene Lookup

3192352  

NCBI Annotation

Similar to AAP96623 Glucosamine--fructose-6-phosphate aminotransferase (isomerizing) from Pseudomonas putida (610 aa). FASTA: opt: 2168 Z-score: 2578.6 E(): 9.7e-136 Smith-Waterman score: 2168; 53.257identity in 614 aa overlap  

TIGR Main Role/Annotations

Central intermediary metabolism  

TIGR Sub Role

Amino sugars  

Comment

 

Selection Phase

Phase 2: March 2008  

Date Approved

Apr 15, 2008  

Justification for Selection

Drug Target Function  

Justification Codes

 

Priority

1  

Sequence Length

612  

(Subtargets)

 

pI

5.78  

Molecular Weight

67.4 kDa  

Sequence

(Check Homologs)

MCGIVGANST RNVTNILIEG LKKLEYRGYD SAGLAIIDDK NNIDICKEVG KVIELEKSVH NLANFKGDIG IAHTRWATHG KPSKNNSHPH ASESFCIVHN GVIENFAELK KVLINDGYKF KSDTDTEVIA HLLQKEWRDN FSIVDNIKYI MAMLKGAYAV AIISQKFSDK IVAVRSGSPL VIGVGIDENF ISSDALSLLP VTNKFSYLDE GDIAIISKDN VEVFDNNGAA KNLEVEEYNY SSSSASKDGY KHYMLKEIYE QPEAVSNTIL ASLADGEISL DSFDKRAKEL FEKTKHICIV ACGTSYNAGM TAKYWIEKYA KVPCSVEIAS EIRYRDNVVV DGSLFVSISQ SGETADTLES LRKSKKQNYV GSMCICNVPN SSLVRESDIA FMTKAGVEIG VASTKAFTTQ LVALAIFTLV IAKLKNSLTD QQIAKYTEEL KNIRALVMGA LKLDTEIDQI SEYFSDKEHT IFLGRGLYYP IAIEGALKLK EISYIHAEAY PSGELKHGPL ALVDKNMPIV AVVPNDELLD KTLSNLQEVH ARGGKLILFV DKAVKERVNF DNSIVLELDA GHDFSAPVVF TIPLQLLSYH VAIIKGTDVD QPRNLAKSVT VE  

DNA Sequence

ATGTGT GGAATA GTAGGT GCTAAC TCTACA AGAAAT GTTACT AATATC TTAATT GAAGGT TTAAAA AAACTA GAGTAC AGAGGT TATGAT TCTGCT GGTTTG GCAATA ATTGAT GATAAA AATAAT ATAGAT ATATGT AAAGAA GTTGGT AAAGTT ATTGAA CTAGAG AAATCT GTACAT AACTTA GCTAAT TTTAAA GGAGAT ATAGGT ATTGCT CATACT AGATGG GCTACT CATGGT AAACCA TCTAAG AATAAT TCTCAC CCTCAT GCTTCG GAAAGC TTTTGT ATAGTC CATAAT GGAGTC ATAGAG AACTTT GCTGAG CTTAAA AAAGTT CTTATT AATGAT GGTTAT AAATTT AAGTCA GATACT GATACT GAGGTT ATCGCA CATTTG CTACAA AAAGAA TGGCGT GATAAT TTTAGC ATAGTT GATAAT ATTAAA TATATT ATGGCT ATGCTT AAGGGA GCATAT GCCGTA GCAATA ATCTCA CAAAAA TTCTCT GATAAA ATTGTT GCGGTG CGTTCA GGTTCG CCACTT GTAATT GGTGTG GGTATA GATGAG AATTTT ATTTCA TCAGAT GCATTA TCATTA TTACCA GTTACA AATAAA TTTTCT TATCTT GATGAA GGTGAC ATTGCA ATTATT TCTAAA GACAAT GTTGAG GTTTTT GATAAT AATGGT GCAGCA AAAAAT CTTGAG GTTGAG GAGTAT AATTAC TCTTCA TCAAGC GCCTCT AAAGAT GGTTAT AAGCAT TATATG CTCAAA GAAATA TATGAG CAGCCA GAGGCA GTTTCA AATACT ATCTTA GCATCA TTAGCT GATGGT GAAATT AGTCTG GATAGT TTTGAT AAAAGA GCTAAA GAATTA TTTGAA AAAACC AAACAT ATTTGT ATAGTT GCATGT GGAACT AGCTAT AATGCT GGGATG ACAGCA AAGTAT TGGATT GAAAAA TATGCA AAAGTT CCATGT AGTGTC GAAATA GCAAGT GAGATT AGGTAT AGAGAT AATGTT GTGGTT GATGGT TCTTTG TTTGTC AGTATT TCTCAA TCTGGT GAAACA GCAGAT ACTCTA GAGTCA CTTAGA AAGAGC AAAAAG CAAAAT TATGTT GGCAGT ATGTGC ATTTGT AATGTG CCAAAT AGTTCG CTTGTG AGAGAA TCTGAT ATTGCT TTTATG ACAAAA GCTGGT GTTGAA ATTGGA GTGGCT TCAACC AAGGCA TTTACA ACACAG TTGGTG GCATTA GCAATA TTTACA TTGGTA ATTGCT AAACTC AAAAAT AGTTTA ACAGAT CAACAG ATAGCT AAATAT ACTGAA GAACTT AAAAAT ATCAGA GCTTTG GTTATG GGAGCC TTAAAA CTAGAT ACTGAA ATAGAT CAGATA AGTGAG TATTTT TCTGAT AAAGAG CATACT ATCTTT TTAGGA AGAGGA TTATAT TATCCT ATAGCT ATTGAA GGGGCC TTAAAA CTTAAA GAGATC TCTTAT ATCCAT GCTGAA GCATAC CCATCA GGAGAG TTAAAG CATGGT CCTCTA GCTCTA GTTGAT AAGAAT ATGCCA ATAGTT GCAGTT GTGCCA AATGAT GAATTA TTAGAT AAAACC TTATCT AACTTA CAGGAA GTACAT GCTCGA GGCGGC AAGCTA ATTCTT TTTGTT GATAAA GCTGTT AAAGAA AGAGTT AACTTT GATAAT AGTATT GTGCTA GAGTTA GATGCA GGACAT GATTTT AGTGCG CCTGTG GTATTT ACGATA CCGCTT CAGCTG TTGTCA TATCAT GTGGCT ATAATC AAAGGA ACGGAT GTTGAT CAACCT AGAAAC TTAGCT AAATCT GTAACC GTTGAG TAA  

Inserted

Apr 23, 2008