Target   IDP00624

Stage

in_pdb   : 3QFH, 3T41

Locus Tag/Selection DB Lookup

SACOL1874  

NCBI Protein Lookup

gi: 57284795   accession: YP_186702  

Organism

Staphylococcus aureus subsp. aureus COL  

Common Name

epidermin leader peptide processing serine protease EpiP  

Gene Name

epiP  

NCBI Gene Lookup

3237868  

NCBI Annotation

identified by similarity to EGAD:8533; match to protein family HMM PF00082  

TIGR Main Role/Annotations

Cellular processes  

TIGR Sub Role

Toxin production and resistance  

Comment

 

Selection Phase

Community Requests  

Date Approved

Apr 15, 2008  

Justification for Selection

Drug Target Function  

Justification Codes

 

Priority

8  

Sequence Length

457  

(Subtargets)

 

pI

9.49  

Molecular Weight

50.7 kDa  

Sequence

(Check Homologs)

MKIIKRAIIS LIILSLLISI TMSNASASEE LYYSVEYKNT ATFNKLVKKK SLNVVYNIPE LHVAQIKMTK MHANALANYK NDIKYINATC STCITSEKTI DRTSNESLFS RQWDMNKITN NGASYDDLPK HANTKIAIID TGVMKNHDDL KNNFSTDSKN LVPLNGFRGT EPEETGDVHD VNDRKGHGTM VSGQTSANGK LIGVAPNNKF TMYRVFGSKK TELLWVSKAI VQAANDGNQV INISVGSYII LDKNDHQTFR KDEKVEYDAL QKAINYAKKK KSIVVAAAGN DGIDVNDKQK LKLQREYQGN GEVKDVPASM DNVVTVGSTD QKSNLSEFSN FGMNYTDIAA PGGSFAYLNQ FGVDKWMNEG YMHKENILTT ANNGRYIYQA GTSLATPKVS GALALIIDKY HLEKHPDKAI ELLYQHGTSK NNKPFSRYGH GELDVYKALN VANQKAS  

DNA Sequence

ATGAAA ATCATA AAGCGC GCTATT ATTAGT TTAATA ATATTG AGTCTT TTAATA TCTATT ACAATG AGTAAT GCATCA GCGTCA GAAGAA CTATAT TACAGT GTTGAA TACAAA AATACA GCAACA TTTAAC AAGTTA GTTAAA AAGAAG TCCTTA AACGTT GTCTAT AATATA CCGGAA TTACAT GTGGCA CAGATT AAAATG ACGAAA ATGCAT GCTAAT GCTTTA GCAAAC TATAAA AATGAT ATTAAA TATATC AATGCC ACATGT TCAACT TGTATT ACTAGC GAGAAA ACAATA GACAGA ACATCA AATGAG TCATTA TTTTCA AGACAA TGGGAT ATGAAT AAAATA ACCAAT AATGGT GCATCG TATGAT GATTTG CCAAAA CATGCT AACACC AAAATA GCAATC ATAGAT ACAGGT GTGATG AAAAAC CATGAC GATTTG AAAAAT AATTTC TCGACT GATTCT AAAAAT TTAGTA CCTTTA AACGGT TTTAGA GGTACT GAACCG GAGGAA ACAGGT GATGTT CACGAT GTCAAT GATAGG AAAGGA CATGGC ACGATG GTGTCG GGTCAA ACGAGT GCTAAT GGTAAG TTAATA GGTGTT GCACCG AATAAC AAATTT ACAATG TATCGC GTGTTT GGTAGT AAAAAA ACAGAA CTGCTT TGGGTA TCAAAA GCGATT GTTCAA GCTGCA AATGAT GGAAAT CAAGTC ATTAAT ATTAGT GTTGGT AGTTAT ATTATT TTGGAC AAAAAT GACCAT CAAACA TTTAGA AAAGAT GAAAAA GTAGAA TACGAT GCGTTA CAGAAA GCAATC AATTAC GCCAAG AAGAAA AAATCT ATCGTT GTTGCT GCAGCT GGTAAT GATGGT ATTGAT GTCAAT GACAAA CAGAAA CTAAAA TTACAG CGTGAA TATCAA GGTAAT GGCGAA GTGAAA GATGTT CCTGCA TCTATG GACAAT GTCGTT ACAGTA GGATCT ACAGAT CAAAAG AGTAAT CTATCT GAGTTT TCCAAT TTTGGT ATGAAT TATACA GATATT GCTGCG CCCGGA GGATCA TTTGCT TATTTA AATCAA TTCGGT GTGGAT AAATGG ATGAAT GAAGGG TATATG CATAAG GAGAAC ATTTTA ACTACT GCCAAT AACGGA AGATAT ATTTAT CAAGCT GGAACT TCATTA GCCACA CCTAAA GTTTCG GGAGCA CTAGCT TTAATC ATTGAT AAATAT CATCTT GAAAAA CATCCA GATAAA GCGATT GAATTG TTATAT CAGCAT GGGACA TCTAAG AATAAT AAACCA TTTAGT AGATAT GGGCAT GGTGAG CTTGAT GTGTAT AAAGCA TTAAAT GTAGCA AATCAA AAAGCA AGTTAA  

Inserted

Apr 23, 2008