Target   IDP01739

Stage

in_pdb   : 3KHY

Locus Tag/Selection DB Lookup

FTT1753  

NCBI Protein Lookup

gi: 56708751   accession: YP_170647  

Organism

Francisella tularensis subsp. tularensis SCHU S4  

Common Name

propionate kinase [Francisella tularensis subsp. tularensis SCHU S4]  

Gene Name

tdcD  

NCBI Gene Lookup

3190747  

NCBI Annotation

Similar to ACKA_CLOTS (Q59331) Acetate kinase (Acetokinase) from Clostridium thermosaccharolyticum (400 aa). FASTA: opt: 1204 Z-score: 1394.5 E(): 8e-70 Smith-Waterman score: 1204; 49.873 identity in 395 aa overlap  

TIGR Main Role/Annotations

Energy metabolism  

TIGR Sub Role

Fermentation  

Comment

 

Selection Phase

Phase 3: June 2008  

Date Approved

Jul 18, 2008  

Justification for Selection

Conserved; Drug target functions  

Justification Codes

 

Priority

1  

Sequence Length

384  

(Subtargets)

 

pI

7.90  

Molecular Weight

42.2 kDa  

Sequence

(Check Homologs)

MSEILVLNCG SSSVKFALIN PHTSQSLVTG LAENIATKNC KVVFKAEHKI VKYLENGSYK DVFEMLKDFL VENKHLEKIV AIGHRVVHGG QYFSKSVLIN ADSLEKIKAC IALAPLHNPA HIEGIRFCQQ IFPELPQVAV FDTAFHQTMP SYIAEYAIPY ELTHKHNIRK YGAHGTSHKY VSEQAAKILT QQKANVIVAH LGNGCSITAV VDGKSIDTSM GLTPLDGLVM GTRSGCIDPS IFAYISDNLG WSVTEITNML NKQSGLLGIC GHNDMREVSQ LAAKGDSLAK LAIEIFSHRV AKFVASYMIY FNKLDALVFT GGIGENAANI RKNIISKLAN LGFMIDHQKN SNSETFINSK NSHNIMVIAT NEELMIAQET QNLI  

DNA Sequence

ATGTCT GAAATA TTAGTA TTAAAT TGCGGT AGTTCT TCAGTT AAGTTT GCACTT ATAAAT CCACAT ACTTCA CAATCT TTAGTT ACAGGT CTTGCA GAAAAC ATTGCT ACTAAA AATTGT AAAGTA GTTTTT AAAGCT GAGCAT AAAATT GTAAAG TACCTT GAGAAT GGTAGT TACAAA GATGTA TTTGAA ATGCTC AAAGAT TTTTTG GTAGAG AATAAA CATCTA GAAAAG ATAGTT GCAATT GGACAT CGGGTA GTTCAT GGAGGT CAGTAT TTTTCT AAATCG GTACTG ATAAAT GCTGAC TCATTA GAAAAA ATAAAA GCGTGT ATTGCA TTAGCG CCATTG CATAAT CCAGCA CATATT GAGGGT ATAAGA TTTTGT CAGCAA ATATTT CCAGAA TTACCT CAGGTA GCTGTG TTTGAT ACAGCA TTTCAT CAGACT ATGCCA AGCTAT ATCGCA GAGTAT GCAATA CCTTAT GAGCTT ACACAC AAGCAT AATATT CGTAAA TATGGC GCACAT GGAACT TCACAT AAATAT GTCTCA GAGCAG GCAGCA AAGATC TTAACT CAACAA AAAGCT AATGTC ATAGTT GCACAT TTAGGT AATGGT TGTAGT ATTACA GCTGTT GTTGAT GGTAAA AGTATC GATACT AGTATG GGGCTT ACTCCT CTAGAT GGACTT GTTATG GGAACA CGCTCA GGCTGT ATTGAC CCTAGT ATTTTT GCATAC ATATCC GATAAC CTTGGT TGGAGT GTCACA GAGATT ACAAAT ATGCTA AACAAG CAAAGT GGTCTA TTAGGT ATTTGC GGACAT AATGAT ATGCGC GAAGTT TCTCAA CTTGCT GCAAAA GGAGAT AGTCTA GCGAAG TTGGCT ATAGAA ATCTTC TCTCAT AGAGTA GCAAAG TTTGTG GCTAGT TATATG ATTTAT TTTAAT AAGTTA GATGCT TTAGTA TTTACA GGAGGT ATTGGT GAGAAT GCTGCT AATATC CGTAAA AATATT ATTTCA AAGCTA GCAAAT CTTGGT TTTATG ATAGAT CATCAA AAAAAC TCTAAT TCAGAG ACATTC ATAAAC AGCAAA AATAGT CATAAT ATAATG GTAATA GCGACT AATGAA GAGCTT ATGATT GCTCAA GAAACA CAAAAT TTAATA TAA  

Inserted

Sep 09, 2008