Target   IDP01791

Stage

in_pdb   : 3UDU, 3UDO

Locus Tag/Selection DB Lookup

Cj1718c  

NCBI Protein Lookup

gi: 15793021   accession: NP_282844  

Organism

Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819  

Common Name

3-isopropylmalate dehydrogenase [Campylobacter jejuni subsp. jejuni NCTC 11168]  

Gene Name

leuB  

NCBI Gene Lookup

905995  

NCBI Annotation

catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis  

TIGR Main Role/Annotations

Hypothetical proteins  

TIGR Sub Role

Conserved  

Comment

 

Selection Phase

Phase 3: June 2008  

Date Approved

Jul 18, 2008  

Justification for Selection

Possible Vaccine Candidate; Predicted Essential-Modeling  

Justification Codes

 

Priority

1  

Sequence Length

358  

(Subtargets)

 

pI

5.03  

Molecular Weight

39.4 kDa  

Sequence

(Check Homologs)

MKTYKVAVLA GDGIGPLVMK EALKILTFIA QKYNFSFEFN EAKIGGASID AYGVALSDET LKLCEQSDAI LFGSVGGPKW DNLPIDQRPE RASLLPLRKH FNLFANLRPC KIYESLTHAS PLKNEIIQKG VDILCVRELT GGIYFGKQDL GKESAYDTEI YTKKEIERIA RIAFESARIR KKKVHLIDKA NVLASSILWR EVVANVAKDY QDINLEYMYV DNAAMQIVKN PSIFDVMLCS NLFGDILSDE LAAINGSLGL LSSASLNDKG FGLYEPAGGS APDIAHLNIA NPIAQILSAA LMLKYSFKEE QAAQDIENAI SLALAQGKMT KDLNAKSYLN TDEMGDCILE ILKENDNG  

DNA Sequence

ATGAAA ACTTAT AAAGTA GCTGTT TTAGCA GGAGAT GGCATA GGGCCT TTGGTG ATGAAA GAGGCT TTAAAA ATTTTA ACTTTT ATCGCA CAAAAA TACAAT TTTAGT TTTGAA TTTAAT GAAGCT AAAATA GGCGGT GCAAGT ATAGAT GCTTAT GGAGTG GCTTTA AGTGAT GAAACT TTAAAG CTTTGT GAGCAA AGTGAT GCGATT TTATTT GGTTCT GTGGGT GGGCCT AAATGG GATAAT TTGCCC ATAGAT CAAAGA CCTGAA AGAGCC TCGCTT TTGCCT TTAAGA AAGCAT TTTAAT TTGTTT GCAAAT TTGCGT CCTTGT AAAATT TATGAA AGTTTA ACCCAT GCTTCA CCTTTA AAAAAT GAGATT ATCCAA AAAGGA GTGGAT ATTTTA TGTGTT AGAGAG CTTACA GGTGGG ATTTAT TTTGGT AAGCAG GATTTA GGTAAA GAAAGT GCGTAT GATACT GAAATT TACACT AAAAAA GAGATA GAAAGG ATAGCT CGTATC GCTTTT GAAAGT GCAAGA ATAAGA AAGAAA AAAGTC CATTTA ATCGAC AAGGCG AATGTT TTAGCA AGTTCT ATTTTG TGGCGA GAAGTG GTGGCA AATGTT GCAAAA GATTAT CAAGAT ATAAAC TTAGAG TACATG TATGTG GATAAT GCTGCG ATGCAG ATTGTA AAAAAT CCTAGC ATTTTT GATGTT ATGCTT TGTTCA AATCTT TTTGGT GATATT TTGAGT GATGAG TTAGCT GCCATT AATGGA TCTTTG GGTTTG TTAAGT TCAGCA AGTTTG AATGAT AAAGGT TTTGGA CTTTAT GAGCCA GCAGGT GGAAGT GCGCCT GATATA GCTCAT TTAAAT ATAGCC AATCCC ATAGCT CAAATT TTAAGT GCGGCT TTGATG TTAAAG TATAGT TTCAAA GAAGAA CAAGCC GCACAG GATATA GAAAAT GCTATA TCTTTG GCATTG GCACAA GGAAAA ATGACT AAGGAT TTAAAT GCTAAG TCGTAT TTAAAT ACCGAT GAAATG GGGGAT TGTATT TTAGAA ATTTTA AAGGAG AATGAC AATGGC TAA  

Inserted

Sep 09, 2008