Target   IDP02630

Stage

expressed  

Locus Tag/Selection DB Lookup

STM2899  

NCBI Protein Lookup

gi: 16766205   accession: NP_461820  

Organism

Salmonella enterica subsp. enterica serovar Typhimurium str. LT2  

Common Name

invasion regulatory protein [Salmonella typhimurium LT2]  

Gene Name

invF  

NCBI Gene Lookup

1254422  

NCBI Annotation

invasion protein InvF (SW:INVF_SALTY); SPI-1 transcription factor; activated by HilA; requires SicA as a co-factor; controls sigD/sopB, sopE and sicAsipBCDA genes  

TIGR Main Role/Annotations

Unclassified  

TIGR Sub Role

Role category not yet assigned  

Comment

 

Selection Phase

Phase 3: June 2008  

Date Approved

Jul 18, 2008  

Justification for Selection

Conserved; Drug target functions  

Justification Codes

 

Priority

1  

Sequence Length

216  

(Subtargets)

 

pI

8.32  

Molecular Weight

24.4 kDa  

Sequence

(Check Homologs)

MSFSESRHNE NCLIQEGALL FCEQAVVAPV SGDLVFRPLK IEVLSKLLAF IDGAGLVDTT YAESDKWVLL SPEFRAIWQD RKRCEYWFLQ QIITPSPAFN KVLALLRKSE SYWLVGYLLA QSTSGNTMRM LGEDYGVSYT HFRRLCSRAL GGKAKSELRN WRMAQSLLNS VEGHENITQL AVNHGYSSPS HFSSEIKELI GVSPRKLSNI IQLADK  

DNA Sequence

ATGTCA TTTTCT GAAAGC CGACAC AATGAA AATTGC CTGATT CAGGAA GGCGCG CTGCTT TTTTGC GAGCAG GCCGTT GTCGCA CCAGTA TCAGGA GACCTG GTTTTT CGACCG TTAAAA ATTGAA GTACTC AGCAAA TTACTG GCATTT ATCGAT GGCGCA GGATTA GTGGAC ACGACA TATGCT GAATCC GATAAA TGGGTT TTGCTG AGTCCT GAGTTT CGCGCT ATTTGG CAAGAT CGTAAA CGCTGC GAGTAC TGGTTT TTGCAG CAAATT ATTACG CCTTCT CCGGCC TTCAAT AAGGTA CTGGCG CTGTTA CGAAAA AGCGAG AGTTAC TGGTTG GTTGGC TATTTA CTCGCT CAGTCA ACCAGC GGCAAC ACGATG AGAATG CTGGGA GAAGAC TATGGC GTTTCT TATACC CATTTT CGTCGT TTGTGC AGCAGA GCGTTG GGCGGA AAAGCG AAGAGT GAATTA CGAAAC TGGCGT ATGGCG CAATCG CTGCTG AATAGT GTAGAA GGCCAC GAGAAC ATCACC CAATTA GCCGTT AATCAT GGTTAC TCATCG CCTTCA CATTTT TCTAGT GAGATC AAAGAG CTGATC GGCGTT TCGCCG CGGAAA TTATCA AATATT ATTCAA TTGGCA GACAAA TGA  

Inserted

Sep 09, 2008