Target   IDP91571

Stage

in_crystallization_trials  

Locus Tag/Selection DB Lookup

BAB35251  

NCBI Protein Lookup

gi: 13361293   accession: BA000007  

Organism

Escherichia coli O157:H7 str. Sakai  

Common Name

hypothetical protein [Escherichia coli O157:H7 str. Sakai]  

Gene Name

ECs1828  

NCBI Gene Lookup

 

NCBI Annotation

 

TIGR Main Role/Annotations

 

TIGR Sub Role

 

Comment

0  

Selection Phase

Community Requests  

Date Approved

Apr 12, 2011  

Justification for Selection

These targets are similar to actual drug targets and will be used mostly for cocrystallisation with small molecules. The more information we have about the binding sites, the better are the chances to understand how the drug works and what modification can achieve.  

Justification Codes

virulence/pathogenesis  

Priority

8  

Sequence Length

169  

(Subtargets)

 

pI

0.00  

Molecular Weight

19.1 kDa  

Sequence

(Check Homologs)

MDAFIVDPVQ GELYSGLSHT ELADIIRLAD SVENQLNGGN SFLDVFSTYM GQVISEFMHS NDNRIELLQR RLHSCSFLVN IEEMSYIDEA LQCPITLAIP QRGVFLRNAE GSRVCSLYDE MALSRIINDG MHHPLSREPI TLSMLVAREQ CEFDCSIGHF TVRSDCYSV  

DNA Sequence

ATGGAC GCTTTT ATTGTA GATCCT GTTCAA GGGGAA CTATAT TCGGGT TTAAGC CATACA GAACTA GCCGAT ATCATT AGATTG GCTGAT TCTGTT GAAAAT CAATTG AATGGA GGCAAT TCATTT CTTGAT GTATTC AGTACA TATATG GGGCAG GTTATT TCTGAA TTTATG CATAGT AATGAT AACAGA ATTGAA TTGTTA CAGCGG CGATTA CATTCA TGTTCA TTTTTA GTTAAT ATTGAA GAAATG TCTTAC ATAGAT GAAGCA TTACAG TGCCCG ATTACG CTGGCA ATTCCT CAACGA GGTGTT TTTTTA AGAAAT GCTGAA GGTTCC AGAGTA TGTAGT TTATAT GATGAA ATGGCT CTTTCT CGTATA ATTAAT GATGGG ATGCAT CACCCA CTAAGC AGAGAG CCAATA ACATTA TCAATG CTTGTG GCCAGA GAGCAG TGTGAG TTTGAT TGCAGT ATCGGT CACTTT ACGGTG AGGAGT GATTGT TATTCA GTGTAG  

Inserted

Apr 12, 2011