Target   IDP91599

Stage

purified  

Locus Tag/Selection DB Lookup

BAB33484  

NCBI Protein Lookup

gi: 13359517   accession: BA000007  

Organism

Escherichia coli O157:H7 str. Sakai  

Common Name

hypothetical protein [Escherichia coli O157:H7 str. Sakai]  

Gene Name

ECs0061  

NCBI Gene Lookup

 

NCBI Annotation

 

TIGR Main Role/Annotations

 

TIGR Sub Role

 

Comment

0  

Selection Phase

Community Requests  

Date Approved

Apr 12, 2011  

Justification for Selection

These targets are similar to actual drug targets and will be used mostly for cocrystallisation with small molecules. The more information we have about the binding sites, the better are the chances to understand how the drug works and what modification can achieve.  

Justification Codes

virulence/pathogenesis  

Priority

8  

Sequence Length

250  

(Subtargets)

 

pI

0.00  

Molecular Weight

28.1 kDa  

Sequence

(Check Homologs)

MKVSVPGMPA TLLNMSNNDI YKMVSGDKMD MKMNIFQRLW ETLRHLFWSD KQTEAYKLLF NFVNKKAGNI NASKYFTGAV NENEKEKFIH SLELFNELKT CAKNPDEMVA KGNMSWVAQT FGDIELSVTF FIENKEICTQ TLQLHKGPGN LGVDLREAYL PGVDMRDCYL GLKTMKGHNK VLYLEPGWNA NLDGATLDGA TLDGATVDGA THLYDEVIII NKITPKKIDT EEVATKQSTA EQITDNAIIE  

DNA Sequence

ATGAAA GTATCA GTTCCA GGCATG CCGGCT ACACTT TTAAAT ATGAGC AATAAC GATATT TATAAG ATGGTG AGCGGG GACAAG ATGGAC ATGAAG ATGAAT ATCTTT CAACGC TTGTGG GAGACG TTACGT CATCTG TTCTGG TCAGAT AAACAG ACTGAG GCTTAT AAACTT CTGTTC AATTTC GTGAAT AAAAAG GCTGGC AACATC AACGCC TCAAAA TACTTT ACTGGG GCTGTC AACGAG AATGAG AAAGAA AAGTTT ATCCAT AGTCTG GAATTA TTCAAT GAACTC AAAACA TGCGCA AAAAAT CCGGAT GAGATG GTCGCA AAGGGC AATATG AGCTGG GTCGCA CAGACC TTCGGT GATATC GAGTTA AGTGTC ACTTTT TTTATT GAAAAT AAGGAG ATATGT ACTCAG ACGTTG CAGCTG CATAAA GGCCCA GGTAAC TTGGGC GTTGAT CTTAGA GAGGCT TACCTT CCCGGC GTTGAC ATGAGG GATTGT TACCTT GGTCTC AAAACA ATGAAA GGTCAC AATAAA GTCCTT TACTTG GAACCT GGGTGG AATGCT AACCTG GACGGT GCTACC CTGGAC GGTGCT ACCCTG GACGGT GCTACC GTGGAC GGTGCT ACCCAC CTATAT GATGAG GTAATT ATTATT AATAAA ATCACC CCCAAA AAAATT GATACT GAAGAA GTTGCT ACTAAA CAAAGT ACTGCT GAACAA ATTACT GACAAC GCAATT ATTGAA TGA  

Inserted

Apr 12, 2011