Structure of IDP92102

Structure of the ornithine aminotransferase from Toxoplasma gondii crystallized in presence of oxidized glutathione reveals partial occupancy of PLP at the protein active site

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CSGID target
IDP92102 
PDB Id
5EQC (NCBI MMDB) 
Authors
E.V.Filippova,G.Minasov,K.Flores,H.V.Le,R.B.Silverman,R.L.Mcleod,W.F.Anderson,Center For Structural Genomics Of Infectious Diseases (Csgid) 
Responsible person
Ekaterina Filippova 
Responsible lab
Northwestern University 
Deposition Date
Nov 12, 2015 
Release Date
Feb 24, 2016 

Annotation

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Ligands

Ligand code Name Ligand type
BGC crystallization
BTB 2-[bis-(2-hydroxy-ethyl)-amino]-2-hydroxymethyl-propane-1,3-diol crystallization
PEG crystallization
PLP pyridoxal-5'-phosphate biological
BME beta mercaptoethanol crystallization
175 3,5-dihydro-5-methylidene-4h-imidazol-4-on

Structure information

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Unit cell parameters

Space Group
P 43  
Unit Cell

a=109.41Å, b=109.41Å, c=109.88Å
α=90.00, β=90.00, γ=90.00 
Solvent content
 
Matthews coefficient
 

Refinement

Data for the highest resolution shell is in parentheses.
Resolution range
109.41-2.20Å (2.26-2.20Å)  
Rall(%)
14.6 
Rwork(%)
14.5 (17.8) 
Rfree(%)
18.1 (22.5) 
Num. observed reflections
65282 (4778) 
Num. Rfree reflections
3198 (203) 
Completeness(%)
100.0 (100.0) 

Model parameters

Num Atoms
6650  
Num Waters
290  
Num Hetatoms
432  
Model mean isotropic B factor
37.350Å2  
RMSD bond length
0.016Å  
RMSD bond angle
1.915°  
Filename uploaded
92102-oxy-con-c_deposit.pdb (uploaded on Nov 12, 2015 4:57 PM)  
Inserted
Nov 12, 2015