Structure of IDP96425

Crystal structure of aminoglycoside resistance enzyme ApmA H135A mutant, complex with tobramycin and coenzyme A

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CSGID target
IDP96425 
PDB Id
7UUO (NCBI MMDB) 
Authors
Stogios, P.J., Evdokimova, E., Michalska, K., Di Leo, R., Bordeleau, E., Wright, G.D., Savchenko, A., Joachimiak, A., Satchell, K.J.F., Center for Structural Genomics of Infectious Diseases (CSGID) 
Responsible person
Peter Stogios 
Responsible lab
University of Calgary 
Deposition Date
Nov 02, 2022 
Release Date
 

Annotation

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Ligands

Ligand code Name Ligand type
TOY tobramycin biological
EDO ethylene diol crystallization
COA Coenzyme A biological

Structure information

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Unit cell parameters

Space Group
P 3  
Unit Cell

a=108.29Å, b=108.29Å, c=87.73Å
α=90.00, β=90.00, γ=120.00 
Solvent content
 
Matthews coefficient
 

Refinement

Data for the highest resolution shell is in parentheses.
Resolution range
29.45-2.65Å (2.72-2.65Å)  
Rall(%)
28.8 
Rwork(%)
28.6 (37.0) 
Rfree(%)
32.8 (41.2) 
Num. observed reflections
34555 (2465) 
Num. Rfree reflections
1693 (122) 
Completeness(%)
97.6 (94.0) 

Model parameters

Num Atoms
6536  
Num Waters
24  
Num Hetatoms
172  
Model mean isotropic B factor
115.200Å2  
RMSD bond length
0.007Å  
RMSD bond angle
1.082°  
RMSD dihedral angle
18.589°
 
Filename uploaded
7uuo.pdb (uploaded on Nov 04, 2022 1:17 PM)  
Inserted
Nov 04, 2022