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Mission: The Center for Structural Genomics of Infectious Diseases is a consortium of laboratories using state-of-the-art structural biology methods to determine the 3-D structures of proteins from major human pathogens (see Overview for more detailed information about our mission).

Latest news:

Protein determined by CSGID featured as the NIAID structure of the month

Laboratories participating in the CSGID are:

Northwestern University

University of Chicago

J. Craig Venter Institute

University College London

University of Toronto

University of Virginia

UT Southwestern Medical Center at Dallas

Washington University School of Medicine

Targets: 6039
Targets requested by the community: 1965
Targets with structures: 329
Structures: 442 (X-ray: 440, NMR: 2)
Structures complexed with ligands: 142
Solved proteins requested by community: 96 (139 structures)
Publications: 21


Target IDP00812     NIAID structure of the month

Title: Crystal Structure of Leukotoxin (LukE) from Staphylococcus aureus subsp. aureus COL.

Authors: Minasov, G., Halavaty, A., Shuvalova, L., Dubrovska, I., Winsor, J., Bagnoli, F., Falugi, F., Bottomley, M., Grandi, G., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP00167    community request

Title: Crystal structure of pre-cleavage form of cysteine protease domain from Vibrio cholerae RtxA toxin

Authors: Shuvalova, L., Minasov, G., Prochazkova, K., Satchell, K.J.F., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP00624    community request

Title: 2.05 Angstrom Resolution Crystal Structure of Epidermin Leader Peptide Processing Serine Protease (EpiP) from Staphylococcus aureus.

Authors: G.Minasov, A.Halavaty, L.Shuvalova, I.Dubrovska, J.Winsor, F.Bagnoli, F.Falugi, M.Bottomley, G.Grandi, W.F.Anderson, Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP00624    community request

Title: 1.95 Angstrom Resolution Crystal Structure of Epidermin Leader Peptide Processing Serine Protease (EpiP) S393A Mutant from Staphylococcus aureus

Authors: G.Minasov, M.Kuhn, J.Ruan, A.Halavaty, L.Shuvalova, I.Dubrovska, J.Winsor, F.Bagnoli, F.Falugi, M.Bottomley, G.Grandi, W.F.Anderson, Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP00770    community request

Title: Crystal Structure of Superantigen-like Protein, Exotoxin SACOL0473 from Staphylococcus aureus subsp. aureus COL

Authors: Filippova, E.V., Minasov, G., Halavaty, A., Shuvalova, L., Winsor, J., Dubrovska, I., Kiryukhina, O., Bagnoli, F., Falugi, F., Bottomley, M., Grandi, G., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP00812    community request

Title: Crystal Structure of Leukotoxin (LukE) from Staphylococcus aureus subsp. aureus COL.

Authors: Minasov, G., Halavaty, A., Shuvalova, L., Dubrovska, I., Winsor, J., Bagnoli, F., Falugi, F., Bottomley, M., Grandi, G., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90163    community request

Title: Crystal Structure of Type I 3-Dehydroquinate Dehydratase (aroD) from Clostridium difficile with Covalent Reaction Intermediate.

Authors: Minasov, G., Light, S.H., Shuvalova, L., Dubrovska, I., Winsor, J., Peterson, S.N., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID).

 
Target IDP90224    community request

Title: Structure of the type III effector/phosphothreonine lyase OspF from Shigella flexneri

Authors: Singer A.U., Skarina T., Nocek B., Gordon R., Lam R., Kagan O., Edwards A.M., Joachimiak A., Chirgadze N.Y., Anderson W.F., Savchenko A., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90225    community request

Title: Structure of a putative YscO homolog CT670 from Chlamydia trachomatis

Authors: Lam, R., Singer, A., Skarina, T., Onopriyenko, O., Bochkarev, A., Brunzelle, J.S., Edwards, A.M., Anderson, W.F., Chirgadze, N.Y., Savchenko, A.

 
Target IDP90246    community request

Title: The Crystal structure of the apo-catalytic domain of DapE protein from V.cholerea

Authors: B.NOCEK,M.MAKOWSKA-GRZYSKA,M.GU,R.JEDRZEJCZAK,W.F.ANDERSON,CSGID

 
Target IDP90246    community request

Title: Crystal structure of the catalytic domain of DapE protein from V.cholerea in the Zn bound form

Authors: B.NOCEK,M.MAKOWSKA-GRZYSKA,M.GU,R.JEDRZEJCZAK,W.F.ANDERSON,A.JOACHIMIAK,CSGID

 
Target IDP90258    community request

Title: 2.35 Angstrom resolution crystal structure of a putative tRNA (guanine-7-)-methyltransferase (trmD) from Staphylococcus aureus subsp. aureus MRSA252

Authors: Halavaty, A.S., Minasov, G., Winsor, J., Dubrovska, I., Shuvalova, L., See, R., Zoraghi, R., Reiner, N., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90271    community request

Title: Crystal Structure of Swine Flu Virus NS1 Effector Domain fromH1N1 Influenza A/California/07/2009.

Authors: D.H. Fremont, Y.Y.L. Yu, C.A. Nelson, Center for Structural Genomics of Infectious Diseases.

 
Target IDP90271    community request

Title: Crystal Structure of Swine Flu Virus NS1 N-Terminal RNA Binding Domain from H1N1 Influenza A/California/07/2009

Authors: Brunzelle, J.S. Wawrzak, Z. Skarina, T. Onopriyenko, O. Savchenko, A. Anderson, W.F. CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES (CSGID)

 
Target IDP90286    community request

Title: 1.85 Angstrom Crystal Structure of Putative Sedoheptulose-1,7 bisphosphatase from Toxoplasma gondii.

Authors: G.Minasov, J.Ruan, Z.Wawrzak, A.Halavaty, L.Shuvalova, O.S.Harb, H.Ngo, W.F.Anderson, Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90293    community request

Title: 2.75 Angstrom Crystal Structure of Enolase 1 from Toxoplasma gondii.

Authors: Minasov G., Ruan J., Shuvalova L., Halavaty A., Tomavo S., Anderson W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90300    community request

Title: 1.8 Angstrom resolution crystal structure of a putative deoxyribose-phosphate aldolase from Toxoplasma gondii ME49

Authors: Halavaty, A.S., Ruan, J., Minasov, G., Shuvalova, L., Ueno, A., Igarashi, M., Ngo, H., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90355    community request

Title: 1.25 ANGSTROM CRYSTAL STRUCTURE OF A PUTATIVE PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN (PEBP) HOMOLOG CT736 FROM CHLAMYDIA TRACHOMATIS D/UW-3/CX

Authors: J.S.BRUNZELLE, Z.WAWRZAK, O.ONOPRIYENKO, A.SAVCHENKO, W.F.ANDERSON, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES (CSGID)

 
Target IDP90506    community request

Title: THE CRYSTAL STRUCTURE OF ASPARTATE ALPHA-DECARBOXYLASE FROM CAMPYLOBACTER JEJUNI SUBSP. JEJUNI NCTC 11168

Authors: TAN,K., GU,M., PETERSON,S., ANDERSON, W.F., JOACHIMIAK, A., CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES (CSGID)

 
Target IDP90513    community request

Title: Crystal Structure of 3-hydroxydecanoyl-(acyl carrier protein) dehydratase from Yersinia pestis

Authors: Zhang, R., Maltseva, N., Kwon, K., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases

 
Target IDP90515    community request

Title: 30S ribosomal protein S15 from Campylobacter jejuni

Authors: Osipiuk, J., Nocek, B., Gu, M., Kwon, K., Anderson, W.F., Joachimiak, A., CSGID

 
Target IDP90517    community request

Title: Crystal structure of a probable undecaprenyl diphosphate synthase (uppS) from Campylobacter jejun

Authors: B.Nocek, M.Gu, S.Grimshaw, W.F.Anderson, A.Joachimiak, Niaid, Center for Structural Genomics of Infectious Diseases (CSGID

 
Target IDP90521    community request

Title: Crystal structure of cytidylyltransferase from Vibrio cholerae

Authors: Hattne, J.; Borek, D.; Grimshaw, S.; Nakka, C.; Rostankowski, R.; Otwinowski, Z.; Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90523    community request

Title: Pantoate-beta-alanine ligase from Yersinia pestis in complex with adenosine monophosphate.

Authors: Osipiuk, J., Maltseva, N., Kwon, K., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90523    community request

Title: Pantoate-beta-alanine ligase from Yersinia pestis in complex with pantoate.

Authors: Osipiuk, J., Maltseva, N., Kwon, K., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90525    community request

Title: 1.77 Angstrom resolution crystal structure of orotidine 5'-phosphate decarboxylase from Vibrio cholerae O1 biovar eltor str. N16961

Authors: Halavaty, A.S. Shuvalova, L. Minasov, G. Dubrovska, I. Winsor, J. Glass, E.M. Peterson, S.N. Anderson, W.F. Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90525    community request

Title: 1.80 Angstrom resolution crystal structure of orotidine 5'-phosphate decarboxylase from Vibrio cholerae O1 biovar eltor str. N16961 in complex with uridine-5'-monophosphate (UMP)

Authors: Halavaty, A.S., Minasov, G., Winsor, J., Shuvalova, L., Kuhn, M., Filippova, E.V., Papazisi, L., Anderson, W.F., Center for Structural Genomics of Infectious Diseases

 
Target IDP90540    community request

Title: Tryptophan synthase subunit alpha from Campylobacter jejuni.

Authors: Osipiuk, J., Gu, M., Kwon, K., Anderson, W.F., Joachimiak, A., CSGID

 
Target IDP90542    community request

Title: Crystal structure of a Nucleoside Diphosphate Kinase from Campylobacter jejuni

Authors: Filippova, E.V., Wawrzak, Z., Onopriyenko, O., Edwards, A., Savchenko, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90544    community request

Title: Crystal Structure of Dihydrofolate Reductase from Yersinia pestis

Authors: Maltseva, N., Kim, Y., Makowska-Grzyska, M., Mulligan, R., Papazisi, L., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90546    community request

Title: 1.8 Angstrom resolution crystal structure of orotidine 5'-phosphate decarboxylase (pyrF) from Campylobacter jejuni subsp. jejuni NCTC 11168

Authors: Halavaty, A.S., Minasov, G., Shuvalova, L., Dubrovska, I., Winsor, J., Papazisi, L., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90549    community request

Title: Phosphopantetheine adenylyltransferase from Yersinia pestis complexed with coenzyme A.

Authors: Osipiuk, J., Maltseva, N., Makowska-Grzyska, M., Kwon, K., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90549    community request

Title: Phosphopantetheine adenylyltransferase from Yersinia pestis.

Authors: Osipiuk, J., Maltseva, N., Makowska-Grzyska, M., Kwon, K., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90555    community request

Title: Crystal Structure of Tryptophanyl-tRNA Synthetase from Campylobacter jejuni

Authors: Kim, Y., Zhou, M., Hasseman, J., Anderson, W.F., Joachimiak, A., CSGID.

 
Target IDP90555    community request

Title: Crystal Structure of Tryptophanyl-tRNA Synthetase from Campylobacter jejuni complexed with ADP and Tryptophane

Authors: Kim, Y., Zhou, M., Grimshaw, S., Anderson, W.F., Joachimiak, A., CSGID

 
Target IDP90557    community request

Title: Crystal structure of putative 3-ketoacyl-(acyl-carrier-protein) reductase from Vibrio cholerae O1 biovar eltor str. N16961 in complex with NADP+

Authors: Hou, J., Chruszcz, M., Onopriyenko, O., Grimshaw, S., Porebski, P., Zheng, H., Savchenko, A., Anderson, W.,Minor, W.

 
Target IDP90557    community request

Title: Crystal structure of 3-ketoacyl-(acyl-carrier-protein)reductase (FabG)from Vibrio cholerae O1

Authors: Hou,J., Chruszcz,M., Cooper,D.R., Grabowski,M., Zheng, H., Shumilin,I., Anderson,W., Minor,W.

 
Target IDP90557    community request

Title: Structure of 3-ketoacyl-(acyl-carrier-protein)reductase (FabG) from Vibrio cholerae O1 complexed with NADP+ (space group P62)

Authors: Hou, J., Chruszcz, M., Cooper, D.R., Grabowski, M., Zheng, H., Shumilin, I., Anderson, W., Minor, W.

 
Target IDP90557    community request

Title: Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (FabG)(Y155F) from Vibrio cholerae

Authors: J.Hou, M.Chruszcz, H.Zheng, M.Grabowski, M.Domagalski, W.F.Anderson, W.Minor, Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90557    community request

Title: Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (FabG)(F187A) from Vibrio cholerae

Authors: J.Hou, M.Chruszcz, H.Zheng, D.R.Cooper, T.Osinski, I.Shumilin, W.F.Anderson, W.Minor, Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90557    community request

Title: Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (FabG) (G92A) from Vibrio cholerae

Authors: Hou, J., Chruszcz, M., Zheng, H., Grabowski, M., Domagalski, M., Anderson, W., Minor, W.

 
Target IDP90557    community request

Title: Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (FabG)(G92D) from Vibrio cholerae

Authors: Hou, J., Chruszcz, M., Zheng, H., Grabowski, M., Fratczak, Z., Anderson, W., Minor, W.

 
Target IDP90564    community request

Title: High resolution crystal structure of transketolase from Campylobacter jejuni subsp. jejuni NCTC 11168

Authors: Nocek B., Makowska-Grzyska M., Maltseva N., Grimshaw S., Anderson,W., Joachimiak, A.

 
Target IDP90564    community request

Title: Crystal structure of transketolase in complex with thiamin diphosphate and calcium ion

Authors: Nocek, B.,Makowska-Grzyska, M., Maltseva, N., Grimshaw, S., Joachimiak, A, Anderson, W., CSGID, NIAID,

 
Target IDP90564    community request

Title: Crystal structure of transketolase in complex with thiamine diphosphate, ribose-5-phosphate and calcium ion

Authors: Nocek, B., Makowska-Grzyska, M., Maltseva, N., Grimshaw, S., Anderson, W., Joachimiak, A., CSGID

 
Target IDP90564    community request

Title: Crystal structure of transketolase in complex with thiamine diphosphate, ribose-5-phosphate (pyranose form) and magnesium ion

Authors: Nocek, B., Makowska-Grzyska, M., Maltseva, N., Grimshaw, S., Anderson, W., Joachimiak, A., CSGID

 
Target IDP90566    community request

Title: Crystal structure of phosphoserine aminotransferase from Yersinia pestis CO92

Authors: Nocek, B., Maltseva, N.,Papazisi, L.,Anderson, W., Joachimiak, A., CSGID

 
Target IDP90567    community request

Title: Dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase from Yersinia pestis.

Authors: Osipiuk, J., Maltseva, N., Makowska-Grzyska, Papazisi, L., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90572    community request

Title: Crystal Structure of Methionyl-tRNA Formyltransferase fromYersinia pestis complexed with L-methionine

Authors: Maltseva, N.,Kim, Y., Hasseman, J., Anderson, W.F., Joachimiak, A., CSGID

 
Target IDP90574    community request

Title: Crystal structure of acetylornithine aminotransferase (argD) from Campylobacter jejuni

Authors: Anderson, S.M., Wawrzak, Z., Onopriyenko, O., Skarina, T., Anderson, W.F., Savchenko, A., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90587    community request

Title: 2.00 Angstrom resolution crystal structure of a catalytic subunit of an aspartate carbamoyltransferase (pyrB) from Yersinia pestis CO92

Authors: Halavaty, A.S. Minasov, G. Dubrovska, I. Winsor, J. Shuvalova, L. Peterson, S. Anderson, W.F. Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90591    community request

Title: Crystal structure of tryptophanyl-tRNA synthetase from Yersinia pestis CO92

Authors: Nocek,B., Maltseva, N., Papazisi, L., Joachimiak, A. Anderson, W., CSGID,NIAID

 
Target IDP90604    community request

Title: Methionyl-tRNA formyltransferase from Vibrio cholerae.

Authors: Osipiuk, J., Gu, M., Papazisi, L., Anderson, W.F., Joachimiak, A., CSGID

 
Target IDP90608    community request

Title: Crystal Structure of Adenylosuccinate Synthetase from Campylobacter jejuni

Authors: Kim, Y. Gu, M., Kwon, K, Anderson, W.F., Joachimiak, A., CSGID

 
Target IDP90611    community request

Title: 1.8 Angstrom resolution crystal structure of a thymidylate kinase (tmk) from Vibrio cholerae O1 biovar eltor str. N16961 in complex with TMP, thymidine-5'-diphosphate and ADP

Authors: Halavaty, A.S. Minasov, G. Dubrovska, I. Winsor, J. Shuvalova, L. Kwon, K. Anderson, W.F. Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90611    community request

Title: 2.25 Angstrom resolution crystal structure of a thymidylate kinase (tmk) from Vibrio cholerae O1 biovar eltor str. N16961 in complex with thymidine

Authors: Halavaty, A.S., Minasov, G., Shuvalova, L., Winsor, J., Dubrovska, I., Peterson, S., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90626    community request

Title: 1.02 Angstrom resolution crystal structure of 3-phosphoshikimate 1- carboxyvinyltransferase from Vibrio cholerae in complex with shikimate-3-phosphate (partially photolyzed) and glyphosate.

Authors: G.Minasov, S.H.Light, A.Halavaty, G.Shuvalova, L.Papazisi, W.F.Anderson, Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90626    community request

Title: 1.90 Angstrom resolution crystal structure of N-terminal domain 3-phosphoshikimate 1-carboxyvinyltransferase from Vibrio cholerae

Authors: S.H.Light, G.Minasov, A.S.Halavaty, L.Shuvalova, L.Papazisi, W.F.Anderson

 
Target IDP90645    community request

Title: 4-hydroxythreonine-4-phosphate dehydrogenase from Campylobacter jejuni.

Authors: Osipiuk, J., Gu, M., Kwon, K., Anderson, W.F., Joachimiak, A., CSGID

 
Target IDP90646    community request

Title: Crystal Structure of Probable Cytoplasmic L-asparaginase fromCampylobacter jejuni

Authors: Kim, Y., Makowska-Grzyska, M., Maltseva, N., Papazisi, L., Anderson, W.F., Joachimiak, A., CSGID

 
Target IDP90669    community request

Title: 2.00 Angstrom resolution crystal structure of a quinolinate phosphoribosyltransferase from Vibrio cholerae O1 biovar eltor str. N16961

Authors: Halavaty, A.S., Minasov, G., Winsor, J., Dubrovska, I., Shuvalova, L., Peterson, S., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90671    community request

Title: Pyridoxal phosphate biosynthetic protein PdxJ from Campylobacter jejuni.

Authors: Osipiuk, J., Zhou, M., Kwon, K., Anderson, W., Joachimiak, A.

 
Target IDP90671    community request

Title: Pyridoxal phosphate biosynthetic protein PdxJ from Campylobacter jejuni in complex with pyridoxine-5'-phosphate.

Authors: Osipiuk, J., Zhou, M., Kwon, K., Anderson, W., Joachimiak, A.

 
Target IDP90682    community request

Title: Crystal structure of serine hydroxymethyltransferase from Campylobacter jejuni

Authors: Anderson, S.M., Wawrzak, Z., Onopriyenko, O., Hasseman, J., Anderson, W.F., Savchenko, A., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90687    community request

Title: 1.85 Angstrom Resolution Crystal Structure of Fructose-bisphosphate Aldolase (Fba) from Campylobacter jejuni

Authors: G.Minasov, Z.Wawrzak, T.Skarina, O.Onopriyenko, L.Papazisi, A.Savchenko, W.F.Anderson, Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90711    community request

Title: Crystal Structure of Dihydrodipicolinate Synthase from Campylobacter jejuni subsp. jejuni NCTC 11168

Authors: Kim, Y., Zhou, M., Hasseman, J., Anderson, W.F., Joachimiak, A. CSGID

 
Target IDP90711    community request

Title: Crystal Structure of Dihydrodipicolinate Synthase from Campylobacter jejuni

Authors: Kim, Y., Zhou, M., Kwon, K., Anderson, W.F., Joachimiak, A., CSGID

 
Target IDP90717    community request

Title: Crystal structure of Phosphoglycerate Kinase from Campylobacter jejuni.

Authors: Filippova, E.V. Wawrzak, Z. Onopriyenko, O. Edwards, A. Savchenko, A. Anderson, W.F. Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90718    community request

Title: Putative RNA methyltransferase from Yersinia pestis.

Authors: Osipiuk, J., Maltseva, N., Peterson, S., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90718    community request

Title: Putative RNA methyltransferase from Yersinia pestis in complex with S-adenosyl-L-homocysteine.

Authors: Osipiuk, J., Maltseva, N., Peterson, S., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90722    community request

Title: Crystal Structure of Biotin Carboxylase-beta-gamma-ATP Complex fromCampylobacter jejuni

Authors: Maltseva, N., Kim, Y., Makowska-Grzyska M., Mulligan, R., Papazisi, L., Anderson, W.F., Joachimiak, A., CSGID

 
Target IDP90722    community request

Title: Crystal Structure of Biotin Carboxylase-ADP Complex from Campylobacter jejuni

Authors: Maltseva, N., Kim, Y., Makowska-Grzyska M., Mulligan, R., Papazisi, L., Anderson, W.F., Joachimiak, A., CSGID

 
Target IDP90735    community request

Title: Phosphopyruvate hydratase from Campylobacter jejuni.

Authors: Osipiuk, J., Gu, M., Kwon, K., Anderson, W.F., Joachimiak, A., CSGID.

 
Target IDP90748    community request

Title: UDP-N-acetylglucosamine acyltransferase from Campylobacter jejuni.

Authors: Osipiuk, J., Zhou, M., Papazisi, L., Anderson, W., Joachimiak, A., CSGID

 
Target IDP90750    community request

Title: 2.4 Angstrom Crystal Structure of Dihydroorotase (pyrC) from Campylobacter jejuni.

Authors: G.Minasov, A.Halavaty, L.Shuvalova, I.Dubrovska, J.Winsor, L.Papazisi, W.F.Anderson, Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90771    community request

Title: 1.65 Angstrom Resolution Crystal Structure of Type II 3-Dehydroquinate Dehydratase (aroQ) from Yersinia pestis.

Authors: Minasov, G. Light, S.H. Shuvalova, L. Dubrovska, I. Winsor, J. Papazisi, L. Anderson, W.F. Center for Structural Genomics of Infectious Diseases (CSGID).

 
Target IDP90784    community request
Target IDP90784    community request

Title: CRYSTAL STRUCTURE OF LIGAND-FREE BIFUNCTIONAL FOLYLPOLYGLUTAMATE SYNTHASE/DIHYDROFOLATE SYNTHASE FROM YERSINIA PESTIS C092

Authors: B NOCEK,N.MALTSEVA,M.MAKOWSKA-GRZYSKA, L.PAPAZISI,W.ANDERSON,A.JOACHIMIAK,NIAID

 
Target IDP90784    community request
Target IDP90784    community request

Title: Crystal structure of bifunctional folylpolyglutamate synthase/dihydrofolate synthase with Mn, AMPPNP and L-Glutamate bound

Authors: Nocek, B. Makowska-Grzyska, M. Maltseva, N. Anderson, W. Joachimiak, A. CSGID

 
Target IDP90785    community request

Title: 2.1 Angstrom resolution crystal structure of an orotate phosphoribosyltransferase (pyrE) from Vibrio cholerae O1 biovar eltor str. N16961

Authors: Halavaty, A.S. Minasov, G. Shuvalova, L. Dubrovska, I. Winsor, J. Kwon, K. Anderson, W.F. Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90790    community request

Title: Isopropylmalate isomerase small subunit from Campylobacter jejuni.

Authors: Osipiuk, J., Gu, M., Papazisi, L., Anderson, W.F., Joachimiak, A., CSGID.

 
Target IDP90792    community request

Title: 1.45 Angstrom Resolution Crystal Structure of Shikimate 5-Dehydrogenase (aroE) from Vibrio cholerae.

Authors: G.Minasov, S.H.Light, L.Shuvalova, L.Papazisi, W.F.Anderson, Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90792    community request

Title: 2.49 Angstrom resolution crystal structure of shikimate 5-dehydrogenase (aroE) from Vibrio cholerae O1 biovar eltor str. N16961 in complex with shikimate

Authors: Halavaty, A.S. Light, S.H. Shuvalova, L. Papazisi, L. Anderson, W.F. Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90792    community request

Title: 2.4 Angstrom resolution crystal structure of shikimate 5-dehydrogenase (aroE) from Vibrio cholerae O1 biovar eltor str. N16961 in complex with shikimate and NADPH

Authors: Halavaty, A.S. Light, S.H. Minasov, G. Shuvalova, L. Papazisi, L. Anderson, W.F. Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90793    community request

Title: THE CRYSTAL STRUCTURE OF GLYCYL-TRNA SYNTHETASE SUBUNIT ALPHA FROM CAMPYLOBACTER JEJUNI SUBSP. JEJUNI NCTC 11168

Authors: TAN,K.,ZHANG,R.,ZHOU,M.,HASSEMAN,J., ANDERSON,W.F., JOACHIMIAK,A., CSGID

 
Target IDP90793    community request

Title: THE CRYSTAL STRUCTURE OF GLYCYL-TRNA SYNTHETASE SUBUNIT ALPHA FROM CAMPYLOBACTER JEJUNI SUBSP. JEJUNI NCTC IN COMPLEX WITH ATP AND GLYCINE

Authors: TAN, K., ZHANG R., ZHOU, M.,KWON, K., ANDERSON,W.F., JOACHIMIAK,A., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90793    community request

Title: The crystal structure of glycyl-tRNA synthetase subunit alpha from Campylobacter jejuni subsp. jejuni NCTC in complex with ATP

Authors: Tan, K., Zhou, M., Kwon, K., Anderson, W.F., Joachimiak, A.Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90797    community request

Title: Crystal Structure of Pantoate-beta-Alanine Ligase from Salmonella typhimurium

Authors: Kim, Y., Makowska-Grzyska, M., Maltseva, N., Kwon, K., Anderson, W.F., Joachimiak, A., CSGID

 
Target IDP90800    community request

Title: Crystal Structure of Pantoate-Beta-alanine Ligase fromCampylobacter jejuni

Authors: Kim, Y., Zhou, M., Papazisi, L., Anderson, W.F., Joachimiak, A., CSGID

 
Target IDP90800    community request

Title: Crystal Structure of Pantoate--Beta-Alanine Ligase from Campylobacter jejuni complexed with AMP and vitamin B5

Authors: Kim, Y., Zhou, M., Kwon, K, Anderson, W.F., Joachimiak, A., CSGID

 
Target IDP90805    community request

Title: Crystal structure of tryptophanyl-tRNA synthetase from Vibrio cholerae with an endogenous tryptophan

Authors: Cooper, D.R., Kudritska, M., Chruszcz, M., Savchenko A., Anderson, W.F., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90810    community request

Title: Crystal Structure of FolD Bifunctional Protein from Campylobacter jejuni

Authors: Kim, Y., Zhang, R., Makowska-Grzyska, M., Papazisi, L., Anderson, W.F., Joachimiak, A., CSGID

 
Target IDP90820    community request

Title: D-Erythronate-4-Phosphate Dehydrogenase complexed with NAD from Salmonella typhimurium LT2

Authors: E.V.Filippova,Z.Wawrzak, O.Onopriyenko, A.Savchenko, A.Edwards, W.F.Anderson, Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90828    community request

Title: Crystal structure of anabolic ornithine carbamoyltransferase from Campylobacter jejuni subsp. jejuni NCTC 11168

Authors: Shabalin, I.G., Onopriyenko, O., Grimshaw, S., Porebski, P.J., Grabowski, M., Savchenko, A., Chruszcz, M., Anderson, W.F., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90832    community request

Title: Thioredoxin-disulfide reductase from Campylobacter jejuni.

Authors: Osipiuk, J., Zhou, M., Kwon, K., Anderson, W., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90843    community request

Title: Structure of NAD Synthetase from Vibrio cholerae

Authors: Anderson, S.M., Wawrzak, Z., Onopriyenko, O., Peterson, S.N., Anderson, W.F., Savchenko, A., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90844    community request

Title: NH3-dependent NAD synthetase from Campylobacter jejuni subsp. jejuni NCTC 11168 in complex with the nitrate ion

Authors: E.V.Filippova, Z.Wawrzak, O.Onopriyenko, T.Skarina, A.Edwards, A.Savchenko, W.F.Anderson, Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90849    community request

Title: Crystal Structure of Phosphoserine Aminotransferase from Campylobacter jejuni

Authors: Kim, Y., Gu, M., Papazisi, L., Anderson, W.F., Joachimiak, A., CSGID

 
Target IDP90862    community request

Title: 2.2 Angstrom Resolution Crystal Structure of Nuclease Domain of Ribonuclase III (rnc) from Campylobacter jejuni.

Authors: G.Minasov, A.Halavaty, L.Shuvalova, I.Dubrovska, J.Winsor, L.Papazisi, W.F.Anderson, Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90862    community request

Title: Structural Flexibility in Region Involved in Dimer Formation of Nuclease Domain of Ribonuclase III (rnc) from Campylobacter jejuni.

Authors: Minasov, G., Halavaty, A., Shuvalova, L., Dubrovska, I., Winsor, J., Papazisi, L., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90886    community request

Title: 1.8 Angstrom Resolution Crystal Structure of Diaminopimelate Decarboxylase (lysA) from Vibrio cholerae.

Authors: Minasov, G., Halavaty, A., Shuvalova, L., Dubrovska, I., Winsor, J., Papazisi, L., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90895    community request

Title: Crystal Structure of Nicotinate Phosphoribosyltransferasefrom Yersinia pestis

Authors: Maltseva, N., Kim, Y., Gu, M., Anderson, W.F., Joachimiak, A., CSGID

 
Target IDP90905    community request

Title: Phosphoribosylformylglycinamidine cyclo-ligase from Vibrio cholerae.

Authors: Osipiuk, J., Zhou, M., Papazisi, L., Anderson, W., Joachimiak, A.

 
Target IDP90915    community request

Title: Crystal structure of 4-hydroxythreonine-4-phosphate dehydrogenase from Yersinia pestis CO92

Authors: B. Nocek, N. Maltseva, K. Kwon, A. Joachimiak, W. Anderson.

 
Target IDP90922    community request

Title: 1.85 Angstrom Crystal Structure of the 3-Dehydroquinate Dehydratase (aroD) from Salmonella typhimurium LT2.

Authors: Minasov, G., Light, S.H., Shuvalova, L., Papazisi, L., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90922    community request

Title: Crystal Structure of the 3-Dehydroquinate Dehydratase (aroD) from Salmonella typhimurium LT2 with Citrate Bound to the Active Site.

Authors: Minasov, G. Light, S.H. Shuvalova, L. Papazisi, L. Anderson, W.F. Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90922    community request

Title: Crystal Structure of Type I 3-Dehydroquinate Dehydratase (aroD) from Salmonella typhimurium LT2 in CovalentComplex with Dehydroquinate.

Authors: Minasov, G. Light, S.H. Shuvalova, L. Papazisi, L. Anderson, W.F. Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90922    community request

Title: Crystal Structure of K170M Mutant of Type I 3-Dehydroquinate Dehydratase (aroD) from Salmonella typhimurium LT2 in Non-Covalent Complex with Dehydroquinate.

Authors: G.Minasov, S.H.Light, L.Shuvalova, L.Papazisi, W.F.Anderson, Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90922    community request

Title: 1.03 Angstrom Crystal Structure of Q236A Mutant Type I Dehydroquinate Dehydratase (aroD) from Salmonella typhimurium

Authors: Light, S.H., Minasov, G., Shuvalova, L., Papazisi, L., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90922    community request

Title: Crystal Structure of Type I 3-Dehydroquinate Dehydratase (aroD) fromSalmonella typhimurium with close loop conformation.

Authors: Minasov, G., Light, S.H., Shuvalova, L., Papazisi, L., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP90922    community request

Title: Crystal Structure of the 3-Dehydroquinate Dehydratase (aroD) from Salmonella enterica typhimurium LT2 with Malonate and Boric Acid at the Active Site

Authors: S.H.Light, G.Minasov, M-E.Duban, A.S.Halavaty, S.N.Krishna, L.Shuvalova, K.Kwon, Anderson W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP91041    community request

Title: Crystal structure of transcriptional regulator VanUg, form I

Authors: Stogios, P.J., Evdokimova, E., Wawrzak, Z., A. Dong, Depardieu, F., Courvalin, P., Shabalin, I., Chruszcz, M., Minor, W., Savchenko, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP91041    community request

Title: Crystal structure of transcriptional regulator VanUg, form II

Authors: Stogios, P.J., Evdokimova, E., Wawrzak, Z., Depardieu, F., Courvalin, P., Shabalin, I., Chruszcz, M., Minor, W., Savchenko, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP91095    community request

Title: 2.3 Angstrom Crystal Structure of 3-deoxy-manno-octulosonate Cytidylyltransferase (kdsB) from Acinetobacter baumannii.

Authors: G.Minasov, A.Halavaty, L.Shuvalova, I.Dubrovska, J.Winsor, L.Papazisi, W.F.Anderson, Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP91101    community request

Title: Crystal Structure of Superantigen-like Protein, Exotoxin from Staphylococcus aureus subsp. aureus NCTC 8325

Authors: E.V.Filippova, G.Minasov, L.Shuvalova, A.Halavaty, J.Winsor, I.Dubrovska, F.Bagnoli, F.Falugi, M.Bottomley, G.Grandi, W.F.Anderson, Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP91106    community request

Title: 2.05 Angstrom Crystal Structure of Putative 5'-Nucleotidase from Staphylococcus aureus in complex with alpha-ketoglutarate

Authors: G.Minasov, Z.Wawrzak, S.N.Krishna, A.Halavaty, L.Shuvalova, I.Dubrovska, J.Winsor, O.Kiryukhina, F.Bagnoli, F.Falugi, M.Bottomley, G.Grandi, W.F.Anderson, Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP91125    community request

Title: 2.4 Angstrom Crystal Structure of Superantigen-like Protein from Staphylococcus aureus.

Authors: G.Minasov, A.Halavaty, L.Shuvalova, E.V.Filippova, I.Dubrovska, J.Winsor, Bagnoli, F., Falugi, F., Bottomley, M., Grandi, G., W.F.Anderson, Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP91135    community request

Title: 2.0 Angstrom Crystal Structure of Ligand Binding Component of ABC-type Import System from Staphylococcus aureus with Zinc bound.

Authors: G.Minasov, Z.Wawrzak, A.Halavaty, L.Shuvalova, I.Dubrovska, J.Winsor, O.Kiryukhina, F.Bagnoli, F.Falugi, M.Bottomley, G.Grandi, W.F.Anderson, Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP91140    community request

Title: 1.5 Angstrom Crystal Structure of the Complex of Ligand Binding Component of ABC-type Import System from Staphylococcus aureus with Nickel and two Histidines.

Authors: Minasov, G., Halavaty, A., Shuvalova, L., Dubrovska, I., Winsor, J., Kiryukhina, O., Falugi, F., Bottomley, M., Bagnoli, F., Grandi, G., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP91143    community request

Title: 2.2 Angstrom Resolution Crystal Structure of Superantigen-like Protein from Staphylococcus aureus subsp. aureus NCTC 8325.

Authors: Minasov, G., Halavaty, A., Shuvalova, L., Dubrovska, I., Winsor, J., Kiryukhina, O., Falugi, F., Bottomley, M., Bagnoli, F., Grandi, G., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP91154    community request

Title: Structure of a putative lipoprotein from Staphylococcus aureus subsp. aureus NCTC 8325

Authors: E.V.Filippova, A.Halavaty, L.Shuvalova, G.Minasov, I.Dubrovska, J.Winsor, O.Kiryukhina, L.Papazisi, F.Bagnoli, F.Falugi, M.Bottomley, G.Grandi, W.F.Anderson, Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP91166    community request

Title: 1.95 Angstrom Crystal Structure of Shikimate 5-dehydrogenase (AroE) from Salmonella enterica subsp. enterica serovar Typhimurium in Complex with NAD.

Authors: Minasov, G., Light, S.H., Halavaty, A., Shuvalova, L., Dubrovska, I., Winsor, J., Papazisi, L., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID).

 
Target IDP91169    community request

Title: 1.45 Angstrom Crystal Structure of Shikimate 5-dehydrogenase from Listeria monocytogenes in Complex with Shikimate and NAD.

Authors: Minasov, G. Light, S.H. Halavaty, A. Shuvalova, L. Papazisi, L. Anderson, W.F. Center for Structural Genomics of Infectious Diseases (CSGID).

 
Target IDP91169    community request

Title: 2.2 Angstrom Crystal Structure of Shikimate 5-dehydrogenase from Listeria monocytogenes in Complex with NAD.

Authors: Minasov, G. Light, S.H. Halavaty, A. Shuvalova, L. Papazisi, L. Anderson, W.F. Center for Structural Genomics of Infectious Diseases (CSGID).

 
Target IDP91183    community request

Title: Structure of an autocleavage-inactive mutant of the cytoplasmic domain of CT091, the YscU homologue of Chlamydia trachomatis

Authors: Singer, A.U. Wawrzak, Z. Skarina, T. Saikali, P. Anderson, W.F. Savchenko, A.

 
Target IDP91187    community request

Title: Crystal structure of aminoglycoside phosphotransferase APH(2")-Ib/APH(2'')-IIa, apo form

Authors: Stogios P.J., Minasov G., Singer A.U., Tan K., Nocek B., Evdokimova E., Egorova O., Di Leo R., Savchenko A., Anderson W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP91187    community request

Title: Crystal structure of aminoglycoside phosphotransferase APH(2")-Ib/APH(2'')-IIa in complex with ADP

Authors: Stogios P.J., Minasov G., Singer A.U., Tan K., Nocek B., Evdokimova E., Egorova O., Di Leo R., Savchenko A., Anderson W.F., Center for Structural Genomics of Infectious Diseases

 
Target IDP91188    community request

Title: Crystal structure of aminoglycoside phosphotransferase APH(4)-Ia

Authors: Stogios, P.J., Shabalin, I.G., Shakya, T., Evdokmova, E., Fan, Y., Chruszcz, M., Minor, W.,Wright, G.D., Savchenko, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP91189    community request

Title: Crystal structure of aminoglycoside phosphotransferase APH(2")-Id/APH(2")-IVa

Authors: Stogios P.J., Minasov G., Tan K., Nocek B., Singer A.U., Evdokimova E., Egorova, O., Di Leo R., Li H., Shakya T., Wright G.D., Savchenko A., Anderson W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP91189    community request

Title: Crystal structure of aminoglycoside phosphotransferase APH(2")-Id/APH(2")-IVa in complex with HEPES

Authors: Stogios P.J, Minasov G., Tan K., Nocek B., Evdokimova E., Egorova O., Di Leo R., Li H., Savchenko A., Anderson W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP91189    community request

Title: Crystal structure of aminoglycoside phosphotransferase APH(2")-Id/APH(2")-IVa in complex with kanamycin

Authors: Stogios P.J., Minasov G., Osipiuk J., Evdokimova E., Egorova O., Di Leo R., Li H., Savchenko A., Anderson W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP91189    community request

Title: Inhibition of an antibiotic resistance enzyme: crystal structure of aminoglycoside phosphotransferase APH(2")-ID/APH(2")-IVA in complex with kanamycin inhibited with quercetin

Authors: Stogios P.J., Minasov G., Dong A., Evdokimova E., Egorova O., Di Leo R., Li H., Shakya T., Wright G.D., Savchenko A., Anderson W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP91191    community request

Title: Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, ATP-bound

Authors: Stogios, P.J., Tan, K., Evdokimova, E., Egorova, E., Di Leo, R., Savchenko, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID), Ontario Centre for Structural Proteomics (OCSP)

 
Target IDP91202    community request

Title: 1.60 Angstrom Resolution Crystal Structure of a 3-Dehydroquinate Dehydratase-like Protein from Bifidobacterium longum

Authors: S.H.Light, G.Minasov, L.Shuvalova, L.Papazisi, A.Lavie, W.F.Anderson, Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP91206    community request

Title: 1.7 Angstrom Resolution Crystal Structure of Shikimate Kinase from Bacteroides thetaiotaomicron.

Authors: Minasov, G. Light, S.H. Halavaty, A. Shuvalova, L. Papazisi, L. Anderson, W.F. Center for Structural Genomics of Infectious Diseases (CSGID).

 
Target IDP91369    community request

Title: 1.95 Angstrom Resolution Crystal Structure of N-acetyl-D-glucosamine kinase from Vibrio vulnificus.

Authors: G.Minasov, Z.Wawrzak, O.Onopriyenko, T.Skarina, L.Papazisi, A.Savchenko, W.F.Anderson, Center for Structural Genomics of Infectious Diseases (CSGID).

 
Target IDP91384    community request

Title: 2.9 Angstrom Crystal Structure of Ornithine Carbamoyltransferase (ArgF) from Vibrio vulnificus.

Authors: Minasov, G. Halavaty, A. Shuvalova, L. Winsor, J. Dubrovska, I. Papazisi, L. Anderson, W.F. Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP91387    community request

Title: 1.80 Angstrom resolution crystal structure of a putative translation initiation inhibitor from Vibrio vulnificus CMCP6

Authors: Halavaty, A.S., Minasov, G. Filippova, E.V., Dubrovska, I., Winsor, J., Shuvalova, L., Papazisi, L., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)

 
Target IDP91417    community request

Title: 1.60 Angstrom resolution crystal structure of an arginine repressor from Vibrio vulnificus CMCP6

Authors: Halavaty, A.S. Minasov, G. Filippova, E. Shuvalova, L. Winsor, J. Dubrovska, I. Peterson, S. Anderson, W.F. Center for Structural Genomics of Infectious Diseases (CSGID)

 

This project has been funded in whole or in part with Federal funds from the National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, under Contract No. HHSN272200700058C.